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The map label for this gene is nccB [H]

Identifier: 87200163

GI number: 87200163

Start: 2289255

End: 2290436

Strand: Reverse

Name: nccB [H]

Synonym: Saro_2147

Alternate gene names: 87200163

Gene position: 2290436-2289255 (Counterclockwise)

Preceding gene: 87200164

Following gene: 87200162

Centisome position: 64.31

GC content: 67.09

Gene sequence:

>1182_bases
ATGGACTTGGAAACTGGAACGGATCCCAAACGTCTCCTGATCGGAGCGGCAGTGGCAACCCTTATCGTCGGCACTGCGGG
TATCATGCTCGGCCGCACCGTGCTTGCCCCCTCTCCAGCCTCGACAGAGGCGGGGCCATCGGGCGAGGCGGAAGAAGAAG
GCCACGTCGAAGGCCTGGTCGAGATGGACGCCAAGCGTGCTGCATCGGCAGGCATTGTTACCGAGACCGCGCAGGCTGGT
TCCCTCGGTGCCGAAATCCTCGCACAGGGCGTCGTCGCCCCGACGCCGGATGGCGAAGCAATTCTCACTGCCCGCGCCGA
TGGCGCGGTCGTGCGGATCGCCAAGGGTCTCGGCGACGCGGTAGCTGCTGGCGAAACCATTGCCTGGCTGGAGAGCCGGG
ACGCAGCGGCGATTGCCGCTGAGCGGAGTTCCGCCGCAGCGCGTGTTGCGCTCGCCCGATCGACCTTCGAGCGCGAACGG
CGACTCTATGAGGCTAAGGTTACCGCGCGGCAAGATTTCGAAGCCGCCCGCGCCGCGCTGGCTGAGGCGGAAGCCGAGAT
GCGACGCAGCCAGTCGGCGGCGAGCGCGTCGAAAGTGTCCGGCGATGGCCGGACCCTTGCCGTCACCAGTCTGATTGCGG
GGCGGATCACCAAGTCGGATGCGCGGCTCGGCGCCTACGTTTCCGCCGGCACGGAGCTTTTCCGAGTCGCCGATCCTCGC
CGAATCCAGATCAACGCCTCGGTGCTACCCGCCGATGCCCGCCGCGTCTCGCCTGGCGACCGCGCAGTCGTCGAGCTAGT
CGGCGGGGAAACCGTCGGTGCCACAGTTCGCTCGGCAACGCCCAGCCTCGATCCGGAAAGCAAGGTCGCGACCCTCGTCC
TCGTGCCGGACAGCGGCGCTCAACTCACTCCGGGCCAGGGGCTGCGTGTGCGGATCACCCCGCGTAATGCTGTTGCCACT
TCAAGCATCGGCCTGCCGGACGAAGCGGTTCAGTCGGTCGAAGGGCGCGATGTCGTCTTTGTGAAGACCGCCAAGGGCTT
CCAGGCCACGAACGTGACCGTGGGACAACGCAGCGCGGGCCGTGTCGAGATCGTTGCCGGTCTGAAGCCGGGCAGCGTGG
TCGCGACGCGCGGCGCATTTCTTCTGAAGGCCGAACTCGGCAAGGGCGAGGCGGAGCATTGA

Upstream 100 bases:

>100_bases
CGCTCACCGCCACGCGCAAATCCCTGATCGACGCGCGGCTCGACCGCGCCCGCGCGCTGGCCGCGCTGATCCGCGCCAAC
GCGCAGTGAAGGACTTACAC

Downstream 100 bases:

>100_bases
GATGATCGAAAAACTTCTCGATGCGGCCATCCGCTTTCGCTGGGGAGTGATTGTCGTCACTCTCATCGTCGCGGCCTTCG
GCGCCTTTCAGCTGCTCAAG

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MDLETGTDPKRLLIGAAVATLIVGTAGIMLGRTVLAPSPASTEAGPSGEAEEEGHVEGLVEMDAKRAASAGIVTETAQAG
SLGAEILAQGVVAPTPDGEAILTARADGAVVRIAKGLGDAVAAGETIAWLESRDAAAIAAERSSAAARVALARSTFERER
RLYEAKVTARQDFEAARAALAEAEAEMRRSQSAASASKVSGDGRTLAVTSLIAGRITKSDARLGAYVSAGTELFRVADPR
RIQINASVLPADARRVSPGDRAVVELVGGETVGATVRSATPSLDPESKVATLVLVPDSGAQLTPGQGLRVRITPRNAVAT
SSIGLPDEAVQSVEGRDVVFVKTAKGFQATNVTVGQRSAGRVEIVAGLKPGSVVATRGAFLLKAELGKGEAEH

Sequences:

>Translated_393_residues
MDLETGTDPKRLLIGAAVATLIVGTAGIMLGRTVLAPSPASTEAGPSGEAEEEGHVEGLVEMDAKRAASAGIVTETAQAG
SLGAEILAQGVVAPTPDGEAILTARADGAVVRIAKGLGDAVAAGETIAWLESRDAAAIAAERSSAAARVALARSTFERER
RLYEAKVTARQDFEAARAALAEAEAEMRRSQSAASASKVSGDGRTLAVTSLIAGRITKSDARLGAYVSAGTELFRVADPR
RIQINASVLPADARRVSPGDRAVVELVGGETVGATVRSATPSLDPESKVATLVLVPDSGAQLTPGQGLRVRITPRNAVAT
SSIGLPDEAVQSVEGRDVVFVKTAKGFQATNVTVGQRSAGRVEIVAGLKPGSVVATRGAFLLKAELGKGEAEH
>Mature_393_residues
MDLETGTDPKRLLIGAAVATLIVGTAGIMLGRTVLAPSPASTEAGPSGEAEEEGHVEGLVEMDAKRAASAGIVTETAQAG
SLGAEILAQGVVAPTPDGEAILTARADGAVVRIAKGLGDAVAAGETIAWLESRDAAAIAAERSSAAARVALARSTFERER
RLYEAKVTARQDFEAARAALAEAEAEMRRSQSAASASKVSGDGRTLAVTSLIAGRITKSDARLGAYVSAGTELFRVADPR
RIQINASVLPADARRVSPGDRAVVELVGGETVGATVRSATPSLDPESKVATLVLVPDSGAQLTPGQGLRVRITPRNAVAT
SSIGLPDEAVQSVEGRDVVFVKTAKGFQATNVTVGQRSAGRVEIVAGLKPGSVVATRGAFLLKAELGKGEAEH

Specific function: Component of the NCC cation efflux system that confers resistance to nickel, cobalt and cadmium [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40066; Mature: 40066

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLETGTDPKRLLIGAAVATLIVGTAGIMLGRTVLAPSPASTEAGPSGEAEEEGHVEGLV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCCCCHHHHH
EMDAKRAASAGIVTETAQAGSLGAEILAQGVVAPTPDGEAILTARADGAVVRIAKGLGDA
HHHHHHHHCCCCEEECCCCCCCCHHHHHCCCCCCCCCCCEEEEEECCCCEEEEECCCCCH
VAAGETIAWLESRDAAAIAAERSSAAARVALARSTFERERRLYEAKVTARQDFEAARAAL
HHCCCEEEEECCCCCCEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAEAEMRRSQSAASASKVSGDGRTLAVTSLIAGRITKSDARLGAYVSAGTELFRVADPR
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHCCCCCCCHHCEEECCCCEEEEECCCE
RIQINASVLPADARRVSPGDRAVVELVGGETVGATVRSATPSLDPESKVATLVLVPDSGA
EEEEEEEECCCCCCCCCCCCCEEEEEECCCEECCCCCCCCCCCCCCCCEEEEEEECCCCC
QLTPGQGLRVRITPRNAVATSSIGLPDEAVQSVEGRDVVFVKTAKGFQATNVTVGQRSAG
CCCCCCCEEEEECCCCCEEECCCCCCHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCC
RVEIVAGLKPGSVVATRGAFLLKAELGKGEAEH
CEEEEECCCCCCEEEECCEEEEEEECCCCCCCC
>Mature Secondary Structure
MDLETGTDPKRLLIGAAVATLIVGTAGIMLGRTVLAPSPASTEAGPSGEAEEEGHVEGLV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCCCCHHHHH
EMDAKRAASAGIVTETAQAGSLGAEILAQGVVAPTPDGEAILTARADGAVVRIAKGLGDA
HHHHHHHHCCCCEEECCCCCCCCHHHHHCCCCCCCCCCCEEEEEECCCCEEEEECCCCCH
VAAGETIAWLESRDAAAIAAERSSAAARVALARSTFERERRLYEAKVTARQDFEAARAAL
HHCCCEEEEECCCCCCEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAEAEMRRSQSAASASKVSGDGRTLAVTSLIAGRITKSDARLGAYVSAGTELFRVADPR
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHCCCCCCCHHCEEECCCCEEEEECCCE
RIQINASVLPADARRVSPGDRAVVELVGGETVGATVRSATPSLDPESKVATLVLVPDSGA
EEEEEEEECCCCCCCCCCCCCEEEEEECCCEECCCCCCCCCCCCCCCCEEEEEEECCCCC
QLTPGQGLRVRITPRNAVATSSIGLPDEAVQSVEGRDVVFVKTAKGFQATNVTVGQRSAG
CCCCCCCEEEEECCCCCEEECCCCCCHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCC
RVEIVAGLKPGSVVATRGAFLLKAELGKGEAEH
CEEEEECCCCCCEEEECCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961470 [H]