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The map label for this gene is mreB [H]

Identifier: 87200144

GI number: 87200144

Start: 2266590

End: 2267636

Strand: Direct

Name: mreB [H]

Synonym: Saro_2128

Alternate gene names: 87200144

Gene position: 2266590-2267636 (Clockwise)

Preceding gene: 87200141

Following gene: 87200145

Centisome position: 63.64

GC content: 64.18

Gene sequence:

>1047_bases
ATGGCTTCGATCTTTTCCCGATTCTTCAAGTTCGGTTCCCAGAACATCGCGATCGACCTCGGCACGGCCAATACGCTGGT
CTACGTCCAGGATCGCGGCATAGTGCTGAACGAACCTTCCGTCGTCGCCATCGAGACGATCAACGGCATCAAGCGGGTCA
AGGCCGTTGGCGATGATGCGAAGATGATGATGGGCAAGACGCCCGACAACATCGAGGCCATCCGTCCGCTGCGCGACGGC
GTGATCGCCGACATCGAAGTCGCCGAGGAGATGATCAAGCACTTCATCCGCAAGGTCCACGGGTCGAAGAGCCTGCTGCG
CTATCCCGAAATCGTGATCTGCGTGCCCTCGGGCTCGACCAGCGTCGAACGCCGCGCAATCCGCGATGCGGCAAGCAATG
CCGGCGCCAGCCAGGTCTACCTGATCCTCGAACCGATGGCCGCCGCGATCGGCGCCGACATGCCGGTGACCGAACCGGTG
GGCTCGATGGTTGTCGACATCGGCGGCGGCACGACCGAAGTGGCCGTGCTTTCGCTGCGCGGCCTTGCCTATACCACTTC
GGTCCGCGTTGGCGGCGACAAGATGGACGAGGCGATCGTTTCCTACGTGCGTCGCCACCACAACCTGCTGATCGGCGAAT
CCACGGCAGAGCGGATCAAGAAGGACTACGGCATCGCCACGACCCCGGCCGACGGGATCGGCGAAACGATCCACATCAAG
GGCCGCGACCTCGTGAACGGCGTGCCCAAGGAAATCACCATCACGCAGGCCAACGTCGCCGAAGCGCTGTCCGAACCGAT
CGGCGCCATCGTCGAGGGCGTGCGCATCGCGCTTGAGAATACCGCGCCCGAACTGGCCGCCGACATCGTCGACCAGGGCA
TCGTGCTGACCGGTGGCGGCGCGCTGATCCGCGGGCTGGATGAACATCTGCGCGAGGAAACCGGGCTGCCGGTGAGCGTG
GCTGAAGATCCGCTGTCCTGCGTCGCGCTCGGCACCGGCCGCGCGATGGAAGACCCGATCTATCGCGGCGTGCTGATGAC
CGCGTAA

Upstream 100 bases:

>100_bases
GCGGACTTCGCCTGCTAGGAAGCCGCCTTCCCGGGCGCTCATTCTGGAGGGGTCTGGCGCTTGCCCGTGCGTCAAACCGC
AGATTATCACGGATTTCCTG

Downstream 100 bases:

>100_bases
AGACACGGATCTGATCGCATAAGAACGTTGCGGGTTGCAGTGCGGCGCGGAAATCGCGCCGGTTTCAAGGGGTGAACGGA
TGGCGCGGTCGCAGGACCGG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MASIFSRFFKFGSQNIAIDLGTANTLVYVQDRGIVLNEPSVVAIETINGIKRVKAVGDDAKMMMGKTPDNIEAIRPLRDG
VIADIEVAEEMIKHFIRKVHGSKSLLRYPEIVICVPSGSTSVERRAIRDAASNAGASQVYLILEPMAAAIGADMPVTEPV
GSMVVDIGGGTTEVAVLSLRGLAYTTSVRVGGDKMDEAIVSYVRRHHNLLIGESTAERIKKDYGIATTPADGIGETIHIK
GRDLVNGVPKEITITQANVAEALSEPIGAIVEGVRIALENTAPELAADIVDQGIVLTGGGALIRGLDEHLREETGLPVSV
AEDPLSCVALGTGRAMEDPIYRGVLMTA

Sequences:

>Translated_348_residues
MASIFSRFFKFGSQNIAIDLGTANTLVYVQDRGIVLNEPSVVAIETINGIKRVKAVGDDAKMMMGKTPDNIEAIRPLRDG
VIADIEVAEEMIKHFIRKVHGSKSLLRYPEIVICVPSGSTSVERRAIRDAASNAGASQVYLILEPMAAAIGADMPVTEPV
GSMVVDIGGGTTEVAVLSLRGLAYTTSVRVGGDKMDEAIVSYVRRHHNLLIGESTAERIKKDYGIATTPADGIGETIHIK
GRDLVNGVPKEITITQANVAEALSEPIGAIVEGVRIALENTAPELAADIVDQGIVLTGGGALIRGLDEHLREETGLPVSV
AEDPLSCVALGTGRAMEDPIYRGVLMTA
>Mature_347_residues
ASIFSRFFKFGSQNIAIDLGTANTLVYVQDRGIVLNEPSVVAIETINGIKRVKAVGDDAKMMMGKTPDNIEAIRPLRDGV
IADIEVAEEMIKHFIRKVHGSKSLLRYPEIVICVPSGSTSVERRAIRDAASNAGASQVYLILEPMAAAIGADMPVTEPVG
SMVVDIGGGTTEVAVLSLRGLAYTTSVRVGGDKMDEAIVSYVRRHHNLLIGESTAERIKKDYGIATTPADGIGETIHIKG
RDLVNGVPKEITITQANVAEALSEPIGAIVEGVRIALENTAPELAADIVDQGIVLTGGGALIRGLDEHLREETGLPVSVA
EDPLSCVALGTGRAMEDPIYRGVLMTA

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=336, Percent_Identity=58.0357142857143, Blast_Score=384, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36876; Mature: 36745

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIFSRFFKFGSQNIAIDLGTANTLVYVQDRGIVLNEPSVVAIETINGIKRVKAVGDDA
CHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCEEECCCCEEEEEEHHHHHHHHHCCCCH
KMMMGKTPDNIEAIRPLRDGVIADIEVAEEMIKHFIRKVHGSKSLLRYPEIVICVPSGST
HHHCCCCCCCHHHHHHHHCCCEEHHHHHHHHHHHHHHHHCCCCHHCCCCEEEEEECCCCC
SVERRAIRDAASNAGASQVYLILEPMAAAIGADMPVTEPVGSMVVDIGGGTTEVAVLSLR
HHHHHHHHHHHCCCCCCEEEEEEEHHHHHHCCCCCCCCCCCCEEEECCCCCCEEEEEEEC
GLAYTTSVRVGGDKMDEAIVSYVRRHHNLLIGESTAERIKKDYGIATTPADGIGETIHIK
CCEEEEEEEECCCHHHHHHHHHHHHHCCEEEECHHHHHHHHHCCCCCCCCCCCCCEEEEC
GRDLVNGVPKEITITQANVAEALSEPIGAIVEGVRIALENTAPELAADIVDQGIVLTGGG
CCHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCEEEECCH
ALIRGLDEHLREETGLPVSVAEDPLSCVALGTGRAMEDPIYRGVLMTA
HHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCCCCHHHCCEEECC
>Mature Secondary Structure 
ASIFSRFFKFGSQNIAIDLGTANTLVYVQDRGIVLNEPSVVAIETINGIKRVKAVGDDA
HHHHHHHHHCCCCEEEEEECCCCEEEEEECCCEEECCCCEEEEEEHHHHHHHHHCCCCH
KMMMGKTPDNIEAIRPLRDGVIADIEVAEEMIKHFIRKVHGSKSLLRYPEIVICVPSGST
HHHCCCCCCCHHHHHHHHCCCEEHHHHHHHHHHHHHHHHCCCCHHCCCCEEEEEECCCCC
SVERRAIRDAASNAGASQVYLILEPMAAAIGADMPVTEPVGSMVVDIGGGTTEVAVLSLR
HHHHHHHHHHHCCCCCCEEEEEEEHHHHHHCCCCCCCCCCCCEEEECCCCCCEEEEEEEC
GLAYTTSVRVGGDKMDEAIVSYVRRHHNLLIGESTAERIKKDYGIATTPADGIGETIHIK
CCEEEEEEEECCCHHHHHHHHHHHHHCCEEEECHHHHHHHHHCCCCCCCCCCCCCEEEEC
GRDLVNGVPKEITITQANVAEALSEPIGAIVEGVRIALENTAPELAADIVDQGIVLTGGG
CCHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCEEEECCH
ALIRGLDEHLREETGLPVSVAEDPLSCVALGTGRAMEDPIYRGVLMTA
HHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCCCCHHHCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]