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The map label for this gene is merR [H]

Identifier: 87200138

GI number: 87200138

Start: 2261421

End: 2261816

Strand: Reverse

Name: merR [H]

Synonym: Saro_2122

Alternate gene names: 87200138

Gene position: 2261816-2261421 (Counterclockwise)

Preceding gene: 87200142

Following gene: 87200136

Centisome position: 63.51

GC content: 67.93

Gene sequence:

>396_bases
ATGGCAATGACCATTTCCGAACTGGCCAAGGGGGCGGGCGTCGGGGTCGAGACAGTCCGGTTCTATCAACGCAAGGGGCT
GCTGGACGATCCACGCCCAAGCCGCACGGCGCGGCAAGGGCAGCGGCATTACGGCCCGGAAGACCTCCGCCGCCTGCGCT
TCGTGCGCAGCGCGCAAGCTGCCGGCTTCACGCTGGCGGAAATTTCCGAGCTGCTGGCGCTCGATGCAGGGCATGACCGA
CCGCGCGCGCGGGAAATGGCGCGGGCCAGGCTCCATGCCATCGAACAGGAAATCGCGCGGCTGGAAGCGGCGCGGCAATC
GCTGCGCAAGCTGGCGCGCGAATGCGCCAAAGGCGATGCGGGGCCGTGCCCGATCATCGCGGCATTTGAGGGTTAG

Upstream 100 bases:

>100_bases
CGGGGGTGCGACCTGGGCTCGGAAGCGAGGTGATTCGGGGTCTGTGCGTTTGTCATGCACTGCCCTATAGCTTGCGTACC
ATGGTACGGAGTCAAGCGCG

Downstream 100 bases:

>100_bases
GGCTGGGGGGCAGCGCTGGTCGGCCCCTCCCGTCAGGGGAGGGGCGACCCGGCGGTCAGACGTTGAACTTGAAGTGGAGG
ACGTCGCCGTCCTTCACCAC

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 131; Mature: 130

Protein sequence:

>131_residues
MAMTISELAKGAGVGVETVRFYQRKGLLDDPRPSRTARQGQRHYGPEDLRRLRFVRSAQAAGFTLAEISELLALDAGHDR
PRAREMARARLHAIEQEIARLEAARQSLRKLARECAKGDAGPCPIIAAFEG

Sequences:

>Translated_131_residues
MAMTISELAKGAGVGVETVRFYQRKGLLDDPRPSRTARQGQRHYGPEDLRRLRFVRSAQAAGFTLAEISELLALDAGHDR
PRAREMARARLHAIEQEIARLEAARQSLRKLARECAKGDAGPCPIIAAFEG
>Mature_130_residues
AMTISELAKGAGVGVETVRFYQRKGLLDDPRPSRTARQGQRHYGPEDLRRLRFVRSAQAAGFTLAEISELLALDAGHDRP
RAREMARARLHAIEQEIARLEAARQSLRKLARECAKGDAGPCPIIAAFEG

Specific function: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury merR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a pote

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=131, Percent_Identity=35.1145038167939, Blast_Score=72, Evalue=1e-14,
Organism=Escherichia coli, GI1789687, Length=132, Percent_Identity=34.8484848484849, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR011794
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 14465; Mature: 14334

Theoretical pI: Translated: 10.52; Mature: 10.52

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMTISELAKGAGVGVETVRFYQRKGLLDDPRPSRTARQGQRHYGPEDLRRLRFVRSAQA
CCCCHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
AGFTLAEISELLALDAGHDRPRAREMARARLHAIEQEIARLEAARQSLRKLARECAKGDA
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GPCPIIAAFEG
CCCCEEECCCC
>Mature Secondary Structure 
AMTISELAKGAGVGVETVRFYQRKGLLDDPRPSRTARQGQRHYGPEDLRRLRFVRSAQA
CCCHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
AGFTLAEISELLALDAGHDRPRAREMARARLHAIEQEIARLEAARQSLRKLARECAKGDA
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GPCPIIAAFEG
CCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666393 [H]