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The map label for this gene is 87200020

Identifier: 87200020

GI number: 87200020

Start: 2139107

End: 2139586

Strand: Direct

Name: 87200020

Synonym: Saro_2004

Alternate gene names: NA

Gene position: 2139107-2139586 (Clockwise)

Preceding gene: 87200011

Following gene: 87200025

Centisome position: 60.06

GC content: 64.38

Gene sequence:

>480_bases
ATGACAATCGCTGTTGGTGACAAGCTGCCCGACGTGAAGATCGTCAAGGCAACTGCCGAAGGTCCGGAAGCGGTCCAGTC
GGCCGAATACTTCAAGGGCAAGAAGGTCGCCCTGTTCTCCGTCCCCGGCGCGTTCACCCCGACCTGCTCGGCCAAGCACC
TGCCGGGCTACGTCGAGAAGGCCGCGGATCTCAAGGCCAAGGGCATCGACGAAGTGGCGTGCACCGCCGTCAACGACCCG
TTCGTGATGAAGGCTTGGGGCGCCGCCAACGGCTCGTCCGATGTGACCATGCTGGCCGACGGCAACGGCGACCTCGCCGA
AGCGCTCGGCCTTACGATGGACGGCTCGGGATTCGGCCTCGGCAAGCGCGGCCAGCGCTTCTCGATGGTCGTGAACGATG
GCGTCGTCGAGCAGCTCTTCGTCGAAGCTCCGGGCGACTTCAAGGTCAGCTCGGCCGAGCACATGCTCGAAAACCTCTGA

Upstream 100 bases:

>100_bases
TTTGCAGCGAAAGTGCCGCCCCCCGGTTGCACGCGCCCGCGCGCCGCCTATATCCTCACCGCCAGACAAGCCCTCGCGGC
ACAACGAAAGGAATTTGGGG

Downstream 100 bases:

>100_bases
CCGGTTCCGGCCCCCGCACCCGCGGGGGCCGTTCCAATCCCGTCAGAATGAAAGCCTGACCCTGCCGACCACGCGGTCGC
CCGCATGCTTGAGGTCGGCA

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MTIAVGDKLPDVKIVKATAEGPEAVQSAEYFKGKKVALFSVPGAFTPTCSAKHLPGYVEKAADLKAKGIDEVACTAVNDP
FVMKAWGAANGSSDVTMLADGNGDLAEALGLTMDGSGFGLGKRGQRFSMVVNDGVVEQLFVEAPGDFKVSSAEHMLENL

Sequences:

>Translated_159_residues
MTIAVGDKLPDVKIVKATAEGPEAVQSAEYFKGKKVALFSVPGAFTPTCSAKHLPGYVEKAADLKAKGIDEVACTAVNDP
FVMKAWGAANGSSDVTMLADGNGDLAEALGLTMDGSGFGLGKRGQRFSMVVNDGVVEQLFVEAPGDFKVSSAEHMLENL
>Mature_158_residues
TIAVGDKLPDVKIVKATAEGPEAVQSAEYFKGKKVALFSVPGAFTPTCSAKHLPGYVEKAADLKAKGIDEVACTAVNDPF
VMKAWGAANGSSDVTMLADGNGDLAEALGLTMDGSGFGLGKRGQRFSMVVNDGVVEQLFVEAPGDFKVSSAEHMLENL

Specific function: Unknown

COG id: COG0678

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI6912238, Length=161, Percent_Identity=45.9627329192547, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6323138, Length=153, Percent_Identity=33.9869281045752, Blast_Score=74, Evalue=8e-15,
Organism=Drosophila melanogaster, GI78706776, Length=145, Percent_Identity=46.2068965517241, Blast_Score=124, Evalue=3e-29,
Organism=Drosophila melanogaster, GI78709078, Length=145, Percent_Identity=46.2068965517241, Blast_Score=124, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR011906
- InterPro:   IPR014025
- InterPro:   IPR013740
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin; PF08534 Redoxin [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 16540; Mature: 16409

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAVGDKLPDVKIVKATAEGPEAVQSAEYFKGKKVALFSVPGAFTPTCSAKHLPGYVEK
CEEECCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHH
AADLKAKGIDEVACTAVNDPFVMKAWGAANGSSDVTMLADGNGDLAEALGLTMDGSGFGL
HHCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCEEEEECCCCCHHHHHCCEECCCCCCC
GKRGQRFSMVVNDGVVEQLFVEAPGDFKVSSAEHMLENL
CCCCCEEEEEECCCCHHHHEEECCCCEEECHHHHHHHCC
>Mature Secondary Structure 
TIAVGDKLPDVKIVKATAEGPEAVQSAEYFKGKKVALFSVPGAFTPTCSAKHLPGYVEK
EEECCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHH
AADLKAKGIDEVACTAVNDPFVMKAWGAANGSSDVTMLADGNGDLAEALGLTMDGSGFGL
HHCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCEEEEECCCCCHHHHHCCEECCCCCCC
GKRGQRFSMVVNDGVVEQLFVEAPGDFKVSSAEHMLENL
CCCCCEEEEEECCCCHHHHEEECCCCEEECHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]