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The map label for this gene is ppnK

Identifier: 87200001

GI number: 87200001

Start: 2104598

End: 2105383

Strand: Direct

Name: ppnK

Synonym: Saro_1984

Alternate gene names: 87200001

Gene position: 2104598-2105383 (Clockwise)

Preceding gene: 87199999

Following gene: 87200002

Centisome position: 59.09

GC content: 63.61

Gene sequence:

>786_bases
ATGACAATGCCGGAATTTGCGCGCCTTGCCCTTCTGGCATCGCCTACGGATCGGGCGCAGGATGCCTGCGAGGCCCTGCG
CAAGGGCCGCGACTGGGTCCCGCTGGAGGAAGCCGATGCCGCCGTGGTGATCGGTGGCGACGGGTTCATGCTCCAGACCT
TGCACACCATGATCGACATCGATCACATCGTGCCGGCCTTCGGCCTGAACCTCGGCACCGTCGGCTTCCTGATGAACAAG
TACCGGTCGGCCAGGTCGATCGAGGAACGGCTCGCCAAGGCGACGAGGATTGCCGTTTCGCCACTGCGCATGACGGCGAC
GACCAACACCGGCGAAATCCAGTCGTTTTGCGCAATCAACGAAGTCTCGATCCTTCGCGAAACGCGCCAGACCGCGAAAC
TGGAAGTCAGCGTGAACGGCAAGGTGCGGATGCCGGAACTCGCCTGCGACGGCGTGCTTGTCGCGACCCCGGCAGGCTCC
ACAGCCTACAACCTGTCGGCGAACGGCCCTATCCTGCCGCTCTCGTCCAACATGCTGGCACTGACCCCGATCAGCCCCTT
CCGACCGCGCCGCTGGCGCGGCGCAATCCTTCCCGAGACGTACGAGATCGTGTTCAAGGCACTCGAATCGGTCAAGCGGC
CGGTCCTCGTGGTGGCCGACCAGAAGGAAGTCCGCGACGTAAGCGAAGTGCGCGTGAAGGCTTGGCCGGAGCATCGCCTG
ACCCTGATGTTCGACCGTGGGCAGAGTCTGGAGGACCGCATCTTCGCCGAACAGTTCATGGTTTGA

Upstream 100 bases:

>100_bases
CGTTCCGCTAATGCGTCCGGCTCTCGCCAGTTGTGCTTTTGTGCATTGCGTCATGGCGTGGCGCTCCATATCTGCCTCTG
TAGGAATTTACCGGGGGCCG

Downstream 100 bases:

>100_bases
AAATTTTTGAAAGCAGGTGCTTGCCAAACCGGAAACGCCTGTTATTAGCGCGCTCCTGCCCCGGGCAACCGGGGCTGCTC
CCTGATAGCTCAGCGGTAGA

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTMPEFARLALLASPTDRAQDACEALRKGRDWVPLEEADAAVVIGGDGFMLQTLHTMIDIDHIVPAFGLNLGTVGFLMNK
YRSARSIEERLAKATRIAVSPLRMTATTNTGEIQSFCAINEVSILRETRQTAKLEVSVNGKVRMPELACDGVLVATPAGS
TAYNLSANGPILPLSSNMLALTPISPFRPRRWRGAILPETYEIVFKALESVKRPVLVVADQKEVRDVSEVRVKAWPEHRL
TLMFDRGQSLEDRIFAEQFMV

Sequences:

>Translated_261_residues
MTMPEFARLALLASPTDRAQDACEALRKGRDWVPLEEADAAVVIGGDGFMLQTLHTMIDIDHIVPAFGLNLGTVGFLMNK
YRSARSIEERLAKATRIAVSPLRMTATTNTGEIQSFCAINEVSILRETRQTAKLEVSVNGKVRMPELACDGVLVATPAGS
TAYNLSANGPILPLSSNMLALTPISPFRPRRWRGAILPETYEIVFKALESVKRPVLVVADQKEVRDVSEVRVKAWPEHRL
TLMFDRGQSLEDRIFAEQFMV
>Mature_260_residues
TMPEFARLALLASPTDRAQDACEALRKGRDWVPLEEADAAVVIGGDGFMLQTLHTMIDIDHIVPAFGLNLGTVGFLMNKY
RSARSIEERLAKATRIAVSPLRMTATTNTGEIQSFCAINEVSILRETRQTAKLEVSVNGKVRMPELACDGVLVATPAGST
AYNLSANGPILPLSSNMLALTPISPFRPRRWRGAILPETYEIVFKALESVKRPVLVVADQKEVRDVSEVRVKAWPEHRLT
LMFDRGQSLEDRIFAEQFMV

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Escherichia coli, GI1788968, Length=155, Percent_Identity=32.9032258064516, Blast_Score=65, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322509, Length=208, Percent_Identity=31.7307692307692, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325068, Length=235, Percent_Identity=26.8085106382979, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 28896; Mature: 28765

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMPEFARLALLASPTDRAQDACEALRKGRDWVPLEEADAAVVIGGDGFMLQTLHTMIDI
CCCCHHHHHHEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHH
DHIVPAFGLNLGTVGFLMNKYRSARSIEERLAKATRIAVSPLRMTATTNTGEIQSFCAIN
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
EVSILRETRQTAKLEVSVNGKVRMPELACDGVLVATPAGSTAYNLSANGPILPLSSNMLA
HHHHHHHHHHHEEEEEEECCEEECCCCCCCCEEEECCCCCCEEEECCCCCEEEECCCEEE
LTPISPFRPRRWRGAILPETYEIVFKALESVKRPVLVVADQKEVRDVSEVRVKAWPEHRL
EECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCE
TLMFDRGQSLEDRIFAEQFMV
EEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TMPEFARLALLASPTDRAQDACEALRKGRDWVPLEEADAAVVIGGDGFMLQTLHTMIDI
CCCHHHHHHEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHH
DHIVPAFGLNLGTVGFLMNKYRSARSIEERLAKATRIAVSPLRMTATTNTGEIQSFCAIN
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
EVSILRETRQTAKLEVSVNGKVRMPELACDGVLVATPAGSTAYNLSANGPILPLSSNMLA
HHHHHHHHHHHEEEEEEECCEEECCCCCCCCEEEECCCCCCEEEECCCCCEEEECCCEEE
LTPISPFRPRRWRGAILPETYEIVFKALESVKRPVLVVADQKEVRDVSEVRVKAWPEHRL
EECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCE
TLMFDRGQSLEDRIFAEQFMV
EEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA