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The map label for this gene is hfq

Identifier: 87199948

GI number: 87199948

Start: 2045402

End: 2045983

Strand: Direct

Name: hfq

Synonym: Saro_1931

Alternate gene names: 87199948

Gene position: 2045402-2045983 (Clockwise)

Preceding gene: 87199947

Following gene: 87199949

Centisome position: 57.43

GC content: 60.31

Gene sequence:

>582_bases
ATGACCGGCAAGACGCTATCCGCCCGCCCTCGGCCCAAACCCGAACCGGCACCAGTGGCGGAAACTGCGCCGCCCGCACC
CGTCACCGGGCCAAGCGGAGGGAAGGGGCAGAACCTTCAGGACCTGTTCCTCAATCACCTGCGCAAGAACAAGATTCCGG
TCACGATGTTCCTCGTGAAGGGCGTCAAGCTGCAGGGTATCGTCACGTGGTTCGACAACTTTTCGATCCTTCTGCGCCGT
GATGGCCAGTCGCAGCTCGTATACAAGCACGCGATCTCGACAATCATGCCGGGTCAGCAGCTTTCGGTCGCCCATTTCCA
GACCTCCGGTGAGGAGAACGGCAAGAAGGCCCGCCTCCTGCAGGAAGTCTTCCTGTCGAGCGTTCGCGATTCCGGCGTCC
AGGTGACGATGTTCCTCGTCAATGGCGTCATGCTTCAGGGCAAGGTCGCGTCCTATGATCTCTTCTGCATGCTTCTGGAG
CGTGAGGGCTATGTCCAGCTCGCTTACAAGCATGCCGTTTCTACGATTCAGCCTGCCGGCCACGTCGATCTGACCGGGGA
CTGGGATGGCGAGGATTCCTGA

Upstream 100 bases:

>100_bases
ATAAACTCGTCAACGAACCCGGCCAGAGTGGACATCCACGAAGGCCAGATCGCGAAGGCTCCAGAAGGGGCCGAGCCAAT
ACAAAACGGAGTCACGTGAA

Downstream 100 bases:

>100_bases
GTACCTTTGAATTTGGCAACAACACCGGCGAGGTCGCCGGTGAAGTAACCCGTGGCGCGCGCGCCGTGGTCGTCCTCCCC
GATATTCGCCAGCGGGGAGG

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MTGKTLSARPRPKPEPAPVAETAPPAPVTGPSGGKGQNLQDLFLNHLRKNKIPVTMFLVKGVKLQGIVTWFDNFSILLRR
DGQSQLVYKHAISTIMPGQQLSVAHFQTSGEENGKKARLLQEVFLSSVRDSGVQVTMFLVNGVMLQGKVASYDLFCMLLE
REGYVQLAYKHAVSTIQPAGHVDLTGDWDGEDS

Sequences:

>Translated_193_residues
MTGKTLSARPRPKPEPAPVAETAPPAPVTGPSGGKGQNLQDLFLNHLRKNKIPVTMFLVKGVKLQGIVTWFDNFSILLRR
DGQSQLVYKHAISTIMPGQQLSVAHFQTSGEENGKKARLLQEVFLSSVRDSGVQVTMFLVNGVMLQGKVASYDLFCMLLE
REGYVQLAYKHAVSTIQPAGHVDLTGDWDGEDS
>Mature_192_residues
TGKTLSARPRPKPEPAPVAETAPPAPVTGPSGGKGQNLQDLFLNHLRKNKIPVTMFLVKGVKLQGIVTWFDNFSILLRRD
GQSQLVYKHAISTIMPGQQLSVAHFQTSGEENGKKARLLQEVFLSSVRDSGVQVTMFLVNGVMLQGKVASYDLFCMLLER
EGYVQLAYKHAVSTIQPAGHVDLTGDWDGEDS

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=69, Percent_Identity=55.0724637681159, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 21133; Mature: 21001

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGKTLSARPRPKPEPAPVAETAPPAPVTGPSGGKGQNLQDLFLNHLRKNKIPVTMFLVK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
GVKLQGIVTWFDNFSILLRRDGQSQLVYKHAISTIMPGQQLSVAHFQTSGEENGKKARLL
CCEEEEEEEEECCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHH
QEVFLSSVRDSGVQVTMFLVNGVMLQGKVASYDLFCMLLEREGYVQLAYKHAVSTIQPAG
HHHHHHHHCCCCCEEEEEEECCEEEECCCCCCEEEEEEECCCCCEEHHHHHHHHHCCCCC
HVDLTGDWDGEDS
CEEECCCCCCCCC
>Mature Secondary Structure 
TGKTLSARPRPKPEPAPVAETAPPAPVTGPSGGKGQNLQDLFLNHLRKNKIPVTMFLVK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
GVKLQGIVTWFDNFSILLRRDGQSQLVYKHAISTIMPGQQLSVAHFQTSGEENGKKARLL
CCEEEEEEEEECCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHH
QEVFLSSVRDSGVQVTMFLVNGVMLQGKVASYDLFCMLLEREGYVQLAYKHAVSTIQPAG
HHHHHHHHCCCCCEEEEEEECCEEEECCCCCCEEEEEEECCCCCEEHHHHHHHHHCCCCC
HVDLTGDWDGEDS
CEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA