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The map label for this gene is btuE [C]

Identifier: 87199786

GI number: 87199786

Start: 1863782

End: 1864270

Strand: Direct

Name: btuE [C]

Synonym: Saro_1769

Alternate gene names: 87199786

Gene position: 1863782-1864270 (Clockwise)

Preceding gene: 87199785

Following gene: 87199787

Centisome position: 52.33

GC content: 60.94

Gene sequence:

>489_bases
ATGAGCGGGCCTCGCACCATTGCCGATTTCAAGGCGCGCAAGCCCAACGGCGAGGAAATCGACCTGGCCGAGAAGAAGGG
CAAGGTCCTGCTCGTGGTGAACACCGCATCCAAGTGCGGGTTCACCCCGCAGTACGATGGCCTTGAGGCCCTTTGGCGCC
AATATGGCGAGCGCGGATTTGAAGTTCTCGCCTTTCCCTGCAACCAGTTCGGCAAGCAGGAACCCGGCACGGCGGATGAG
ATCGAAAGCTTCTGCAAGGTCAACTTCGGCCTCAGCTTTCCGCTCATGGCCAAGATCGAGGTCAATGGCGACAACGCCGA
TCCGCTTTACGACTGGCTGAAGAGCGAGGCTCCGGGCGTGCTCGGCACCAAGTCGATCAAGTGGAACTTCACCAAGTTCC
TGATCGACCGCGAAGGCCGCGTGGTCCGCCGCTATGCCCCCACGGACAAGCCGGAAAGCATCGCCGGGGACATCGAAAGG
CTGCTCTGA

Upstream 100 bases:

>100_bases
TGGATGCAACCCAGCGCGCCCGTCTGGTAATCGACGTTGCTGGCGGCAAGTCGCTGAACGTACCTGAAATACTGGCCCTC
GCGGCGCAAGAGGGCCTGGC

Downstream 100 bases:

>100_bases
CCGTCACCAAGGAGTCTGGTGAAAAAGCAGGCCGCGCCTCTCGCAAGAGCGCGGCCTTTTTCCTACCTTGTACACATGCC
CCATGCCGCCTTCGTCCCGC

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MSGPRTIADFKARKPNGEEIDLAEKKGKVLLVVNTASKCGFTPQYDGLEALWRQYGERGFEVLAFPCNQFGKQEPGTADE
IESFCKVNFGLSFPLMAKIEVNGDNADPLYDWLKSEAPGVLGTKSIKWNFTKFLIDREGRVVRRYAPTDKPESIAGDIER
LL

Sequences:

>Translated_162_residues
MSGPRTIADFKARKPNGEEIDLAEKKGKVLLVVNTASKCGFTPQYDGLEALWRQYGERGFEVLAFPCNQFGKQEPGTADE
IESFCKVNFGLSFPLMAKIEVNGDNADPLYDWLKSEAPGVLGTKSIKWNFTKFLIDREGRVVRRYAPTDKPESIAGDIER
LL
>Mature_161_residues
SGPRTIADFKARKPNGEEIDLAEKKGKVLLVVNTASKCGFTPQYDGLEALWRQYGERGFEVLAFPCNQFGKQEPGTADEI
ESFCKVNFGLSFPLMAKIEVNGDNADPLYDWLKSEAPGVLGTKSIKWNFTKFLIDREGRVVRRYAPTDKPESIAGDIERL
L

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=157, Percent_Identity=45.2229299363057, Blast_Score=136, Evalue=9e-33,
Organism=Homo sapiens, GI90903240, Length=157, Percent_Identity=45.2229299363057, Blast_Score=135, Evalue=1e-32,
Organism=Homo sapiens, GI15618997, Length=155, Percent_Identity=43.2258064516129, Blast_Score=125, Evalue=2e-29,
Organism=Homo sapiens, GI192455698, Length=154, Percent_Identity=40.2597402597403, Blast_Score=120, Evalue=7e-28,
Organism=Homo sapiens, GI90903238, Length=132, Percent_Identity=44.6969696969697, Blast_Score=111, Evalue=3e-25,
Organism=Homo sapiens, GI4557629, Length=173, Percent_Identity=37.5722543352601, Blast_Score=97, Evalue=7e-21,
Organism=Homo sapiens, GI33186887, Length=177, Percent_Identity=37.2881355932203, Blast_Score=93, Evalue=1e-19,
Organism=Homo sapiens, GI41406084, Length=183, Percent_Identity=36.6120218579235, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI6006001, Length=173, Percent_Identity=36.4161849710983, Blast_Score=91, Evalue=6e-19,
Organism=Homo sapiens, GI32967607, Length=182, Percent_Identity=32.967032967033, Blast_Score=85, Evalue=3e-17,
Organism=Escherichia coli, GI1788003, Length=156, Percent_Identity=42.9487179487179, Blast_Score=139, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17506887, Length=158, Percent_Identity=43.6708860759494, Blast_Score=143, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17535473, Length=158, Percent_Identity=44.9367088607595, Blast_Score=141, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71993584, Length=158, Percent_Identity=42.4050632911392, Blast_Score=127, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI193210707, Length=162, Percent_Identity=42.5925925925926, Blast_Score=125, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17550320, Length=181, Percent_Identity=34.2541436464088, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI193209493, Length=181, Percent_Identity=33.7016574585635, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=38.9473684210526, Blast_Score=73, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17507603, Length=107, Percent_Identity=36.4485981308411, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71999642, Length=77, Percent_Identity=37.6623376623377, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319721, Length=157, Percent_Identity=52.2292993630573, Blast_Score=191, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6322228, Length=146, Percent_Identity=54.7945205479452, Blast_Score=185, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6322826, Length=147, Percent_Identity=44.8979591836735, Blast_Score=145, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24656772, Length=163, Percent_Identity=50.3067484662577, Blast_Score=150, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24656767, Length=163, Percent_Identity=50.3067484662577, Blast_Score=150, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24656777, Length=163, Percent_Identity=50.3067484662577, Blast_Score=149, Evalue=7e-37,
Organism=Drosophila melanogaster, GI85726443, Length=159, Percent_Identity=40.8805031446541, Blast_Score=114, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 18122; Mature: 17991

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGPRTIADFKARKPNGEEIDLAEKKGKVLLVVNTASKCGFTPQYDGLEALWRQYGERGF
CCCCCCCHHHHCCCCCCCEECCCCCCCCEEEEEECCHHCCCCCCCCCHHHHHHHHCCCCC
EVLAFPCNQFGKQEPGTADEIESFCKVNFGLSFPLMAKIEVNGDNADPLYDWLKSEAPGV
EEEEECCHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCC
LGTKSIKWNFTKFLIDREGRVVRRYAPTDKPESIAGDIERLL
EECCCCCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SGPRTIADFKARKPNGEEIDLAEKKGKVLLVVNTASKCGFTPQYDGLEALWRQYGERGF
CCCCCCHHHHCCCCCCCEECCCCCCCCEEEEEECCHHCCCCCCCCCHHHHHHHHCCCCC
EVLAFPCNQFGKQEPGTADEIESFCKVNFGLSFPLMAKIEVNGDNADPLYDWLKSEAPGV
EEEEECCHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCC
LGTKSIKWNFTKFLIDREGRVVRRYAPTDKPESIAGDIERLL
EECCCCCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]