Click here to switch to the map view.

The map label for this gene is lolC [H]

Identifier: 87199782

GI number: 87199782

Start: 1861258

End: 1862499

Strand: Direct

Name: lolC [H]

Synonym: Saro_1765

Alternate gene names: 87199782

Gene position: 1861258-1862499 (Clockwise)

Preceding gene: 87199781

Following gene: 87199783

Centisome position: 52.26

GC content: 63.29

Gene sequence:

>1242_bases
TTGATCCTGTCTCCGTTCGAATGGACCATCGCCAAGCGCTACATGCTGCCGGGGCGAGGGGAGGCTTTCATCGCACTCGT
CGCCGGTATCAGCCTCGTGGCGGTCATGCTGGGCGTTGCCGCGCTCGTCATCGTGATGAGCGTGATGAACGGCTTCCGCG
CCGAACTGCTCGACAAGATCGTCGGCCTCAACGGCCACGCGATCATCCAGGCCTATGGCGGCCGGCTCGACAACTGGCAG
GACATCCTCAAGCGCGTCCAGCAGACGCCCGACGTGACCCACGCCTCGCCGCTGATCGAGCAGCCGCTGCTCGCCAGCTT
CAACGGCCGAGTCGAGGCGATCCTCGTGCGTGGCAATACGGCGGAGGACATCAAGCGGCTCGAGGACAAGCGCGTCGACG
GTGTCATCGGCTCGCTGCGCCCCGGCTCGGGCAATGTCGCCCTAGGGTCGCGCCTTGCCGAAAACCTTGGCGCGCGCGTG
GGCGACAGCATTACCATCATCAACCCGCAAGGCAGGTCGACCCCGTTCGGCACTGTCCCGCGCGAGATCGCCTATACCGT
TTCAGCGATCTTCGAGGTCGGCGTCTACGACTACGACCAGGCCTATGTCGTCATGCCCATCTCCGATGCGCAGACCCTGC
TGTTGACGGGCGACACTATCGGCATGATCGAGGTGACGACGACCAACGCCGACACGGTGATGGATACCCTGGGGCCGCTC
AAGAAGGAGCTGGAAGGCCAGGCCGTCGTCACGGACTGGAAGACCATCAACGCCAGCCTGTTCGAGGCGCTCGCGGTGGA
ACGCGTGGCGATGTTCATCGTGCTTTCGATCATCGTGCTGGTAGCGGTGTTCAACATCCTGTCATCGCTGATCATGCTGG
TACGCGCCAAGACCCGCGACATCGCGATTCTGCGCACGATGGGGGCGACGCGAAAGAGCCTGCTCAAGATCTTCGTGACC
ATCGGTTTCGTGATCGGGGCGCTGGGCACCCTATCGGGGCTCGCGCTCGGCTTCGTGTTCCTGTTCTTCCGCCAGCCCAT
CGTCAACGCGATCCAGTATCTCACCGGGCAGAACCTGTGGGACCCCTCGATCCGTTTCCTCACCGAACTGCCGAGCCGCT
CCGATCCCGTGGAGATCACCACGATCTGCCTGATGGCGCTGCTGTTCAGCTTCCTTGCGACTCTTTATCCGGCGCTCAAG
GCGGCGAGCACGGACCCCGTTCAGGTGCTGCGTTATGAGTGA

Upstream 100 bases:

>100_bases
ACCCGGATTGACTGTTGCGCCGACGGCCATTGCCGTTTGCGCCGCAGGGCCCTAAATCCGCACGGCCAGATCCGGCCGAA
TACATCCAAAGGGCTGCTTC

Downstream 100 bases:

>100_bases
TCCAGTGGTGCGCCTGCGCGAGCTGCGCCGTTCCTTCAGCCAGGGCGGGGTCACCATCGACGTCCTGCGCGGCGTCAACC
TCGAGATCCGCCCCGGCGAG

Product: LolC/E family lipoprotein releasing system, transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MILSPFEWTIAKRYMLPGRGEAFIALVAGISLVAVMLGVAALVIVMSVMNGFRAELLDKIVGLNGHAIIQAYGGRLDNWQ
DILKRVQQTPDVTHASPLIEQPLLASFNGRVEAILVRGNTAEDIKRLEDKRVDGVIGSLRPGSGNVALGSRLAENLGARV
GDSITIINPQGRSTPFGTVPREIAYTVSAIFEVGVYDYDQAYVVMPISDAQTLLLTGDTIGMIEVTTTNADTVMDTLGPL
KKELEGQAVVTDWKTINASLFEALAVERVAMFIVLSIIVLVAVFNILSSLIMLVRAKTRDIAILRTMGATRKSLLKIFVT
IGFVIGALGTLSGLALGFVFLFFRQPIVNAIQYLTGQNLWDPSIRFLTELPSRSDPVEITTICLMALLFSFLATLYPALK
AASTDPVQVLRYE

Sequences:

>Translated_413_residues
MILSPFEWTIAKRYMLPGRGEAFIALVAGISLVAVMLGVAALVIVMSVMNGFRAELLDKIVGLNGHAIIQAYGGRLDNWQ
DILKRVQQTPDVTHASPLIEQPLLASFNGRVEAILVRGNTAEDIKRLEDKRVDGVIGSLRPGSGNVALGSRLAENLGARV
GDSITIINPQGRSTPFGTVPREIAYTVSAIFEVGVYDYDQAYVVMPISDAQTLLLTGDTIGMIEVTTTNADTVMDTLGPL
KKELEGQAVVTDWKTINASLFEALAVERVAMFIVLSIIVLVAVFNILSSLIMLVRAKTRDIAILRTMGATRKSLLKIFVT
IGFVIGALGTLSGLALGFVFLFFRQPIVNAIQYLTGQNLWDPSIRFLTELPSRSDPVEITTICLMALLFSFLATLYPALK
AASTDPVQVLRYE
>Mature_413_residues
MILSPFEWTIAKRYMLPGRGEAFIALVAGISLVAVMLGVAALVIVMSVMNGFRAELLDKIVGLNGHAIIQAYGGRLDNWQ
DILKRVQQTPDVTHASPLIEQPLLASFNGRVEAILVRGNTAEDIKRLEDKRVDGVIGSLRPGSGNVALGSRLAENLGARV
GDSITIINPQGRSTPFGTVPREIAYTVSAIFEVGVYDYDQAYVVMPISDAQTLLLTGDTIGMIEVTTTNADTVMDTLGPL
KKELEGQAVVTDWKTINASLFEALAVERVAMFIVLSIIVLVAVFNILSSLIMLVRAKTRDIAILRTMGATRKSLLKIFVT
IGFVIGALGTLSGLALGFVFLFFRQPIVNAIQYLTGQNLWDPSIRFLTELPSRSDPVEITTICLMALLFSFLATLYPALK
AASTDPVQVLRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=412, Percent_Identity=29.126213592233, Blast_Score=168, Evalue=7e-43,
Organism=Escherichia coli, GI1787360, Length=417, Percent_Identity=30.2158273381295, Blast_Score=140, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44843; Mature: 44843

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILSPFEWTIAKRYMLPGRGEAFIALVAGISLVAVMLGVAALVIVMSVMNGFRAELLDKI
CCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGLNGHAIIQAYGGRLDNWQDILKRVQQTPDVTHASPLIEQPLLASFNGRVEAILVRGNT
HCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCHHHHCCHHHCCCCCEEEEEEECCC
AEDIKRLEDKRVDGVIGSLRPGSGNVALGSRLAENLGARVGDSITIINPQGRSTPFGTVP
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCHHCCCCEEEECCCCCCCCCCCCH
REIAYTVSAIFEVGVYDYDQAYVVMPISDAQTLLLTGDTIGMIEVTTTNADTVMDTLGPL
HHHHHHHHHHHHHCCEECCCCEEEEEECCCCEEEEECCCEEEEEEECCCHHHHHHHHHHH
KKELEGQAVVTDWKTINASLFEALAVERVAMFIVLSIIVLVAVFNILSSLIMLVRAKTRD
HHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IAILRTMGATRKSLLKIFVTIGFVIGALGTLSGLALGFVFLFFRQPIVNAIQYLTGQNLW
CHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DPSIRFLTELPSRSDPVEITTICLMALLFSFLATLYPALKAASTDPVQVLRYE
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEECC
>Mature Secondary Structure
MILSPFEWTIAKRYMLPGRGEAFIALVAGISLVAVMLGVAALVIVMSVMNGFRAELLDKI
CCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGLNGHAIIQAYGGRLDNWQDILKRVQQTPDVTHASPLIEQPLLASFNGRVEAILVRGNT
HCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCHHHHCCHHHCCCCCEEEEEEECCC
AEDIKRLEDKRVDGVIGSLRPGSGNVALGSRLAENLGARVGDSITIINPQGRSTPFGTVP
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCHHCCCCEEEECCCCCCCCCCCCH
REIAYTVSAIFEVGVYDYDQAYVVMPISDAQTLLLTGDTIGMIEVTTTNADTVMDTLGPL
HHHHHHHHHHHHHCCEECCCCEEEEEECCCCEEEEECCCEEEEEEECCCHHHHHHHHHHH
KKELEGQAVVTDWKTINASLFEALAVERVAMFIVLSIIVLVAVFNILSSLIMLVRAKTRD
HHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IAILRTMGATRKSLLKIFVTIGFVIGALGTLSGLALGFVFLFFRQPIVNAIQYLTGQNLW
CHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DPSIRFLTELPSRSDPVEITTICLMALLFSFLATLYPALKAASTDPVQVLRYE
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]