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The map label for this gene is dapE [H]

Identifier: 87199687

GI number: 87199687

Start: 1750798

End: 1752201

Strand: Direct

Name: dapE [H]

Synonym: Saro_1670

Alternate gene names: 87199687

Gene position: 1750798-1752201 (Clockwise)

Preceding gene: 87199686

Following gene: 87199689

Centisome position: 49.16

GC content: 64.03

Gene sequence:

>1404_bases
ATGAAGCTCAAGTCATTGTTCCACTTGTCCATTGTCTCCTCCTTGGCGCTCGTCGGCGCTGCTTCGGCGAAGGACGCCGC
CTATCCTCGGGCAGAGGCGCAGACGCTCGACCTGGCGCAGAAGGCCATCGCAATCCGTTCCGTGCGGGGCGAGGGGAACA
GGACCATCGACGTCGCCAACCTTTTCCGCGACGCACTGCTCAAGGGCGGCTGGCAGGTTGGCGACATCGAGGTGACGCCG
GTCGATGACACTGCCTACATCATCGCCACGTGGAAGGGCTCGGACCCCTCGCTCAAGCCGGTGGTCATCTCCGGCCACAT
GGATGTGGTCGAAGCCAAGCGCGAGGATTGGGAGCGCGATCCTTTCGTGCCGGTCGTCGAGAACGGCATCCTTTACGGTC
GCGGGGCAAGCGACATGAAGTTCGACGGCGCGCTGGCGCTGTCCACGCTGATCGAACTTCGGCGCCAGGGTTTCAAGCCG
AAGCGCACGATCGTCATCGAGTTTTCCGGCGACGAGGAGACCACGATGAAGACCAGCGCGATCATCGCGGAAAAACTCAA
GAACGCGGAACTGGTGATCAACGTCGATGGCGGCGGCGGCACTCTCGACGAGGCGACGGGCAAGCCGCTCTACTGGACCT
GGCAGGGCGCTGAAAAGACTTATGCCGATTACCGGCTGGAGGTGACCAATCCGGGCGGCCACAGCTCCGCCCCGCGCCCG
GACAATGCCATCGTCCAGCTATCGCAGGCGCTGGTGAAGGTGGGGGCCTACAGGTTCAAGGCTGAACAGAACGACATCAC
CAGGGGCTATTTCGAAAAGGCGGCGCCCTTTACCGACAGGCCCGAGATTGCCGCCGCGATGCGCGCCTTCGCCGCCAACC
CGGCGGACGAGAAGGCACTGGCGACCCTGCGGGCCGATCCATCCATGGTCGGCAAGGTCGGGACGACCTGCGTTCCGACC
ATGCTCGGCGGCGGCCATGCCGAGAACGCGCTGCCGCAGCGCGCCTTCGCCAACATCAATTGCCGAATCTTCCCCGGCCA
CACCAAGGAGGCGATCATGGCTGAGCTGGCGCAGGTGGTCGGCGATCCGGCTGTGAAGATCAGCGACGTGACCGAAGGTT
CGGTCGCATCGCCCGCGTCCCCGCTGCGGCCCGACCTGATGAAGGCTGTGACCAGGGCAATGACCAAGGCCTACCCCAAA
GTGCCGTTGATCCCTTCACAGGCATCGGGCGCTTCGGATTCCATGTGGTTCCGCGCGCTCGGCGTGCCGAGCTATGGGCT
CAGCCCCTCGTTCTCGAAGGACAGCGAGGACTTCTCGCACGGCCTCAACGAGCGGACGCGGTTGTCCAATATCCGGCCGG
GGATCACCTACTACCTGACCCTGATCACCGACCTCACGAAATGA

Upstream 100 bases:

>100_bases
AAGGCCCCGGTCGCCCATGCGGCCGGGGCCTTTTGCTTGCGAAAGTGGTTGCCAGCGAACCGCGTCCACGCCAGCTTCGG
CGGATCAGGGAGTCGTGCAT

Downstream 100 bases:

>100_bases
TCGAGGCGAGGAAGCTGCGGGCGATGTCCCGCGCATCCTCGGCCGAGAAGCAGCCCGGCGAGAGGCACAGCTCCAGCCAC
AGTCCGTCGACCAGCGCGGT

Product: hypothetical protein

Products: NA

Alternate protein names: SDAP desuccinylase [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKLKSLFHLSIVSSLALVGAASAKDAAYPRAEAQTLDLAQKAIAIRSVRGEGNRTIDVANLFRDALLKGGWQVGDIEVTP
VDDTAYIIATWKGSDPSLKPVVISGHMDVVEAKREDWERDPFVPVVENGILYGRGASDMKFDGALALSTLIELRRQGFKP
KRTIVIEFSGDEETTMKTSAIIAEKLKNAELVINVDGGGGTLDEATGKPLYWTWQGAEKTYADYRLEVTNPGGHSSAPRP
DNAIVQLSQALVKVGAYRFKAEQNDITRGYFEKAAPFTDRPEIAAAMRAFAANPADEKALATLRADPSMVGKVGTTCVPT
MLGGGHAENALPQRAFANINCRIFPGHTKEAIMAELAQVVGDPAVKISDVTEGSVASPASPLRPDLMKAVTRAMTKAYPK
VPLIPSQASGASDSMWFRALGVPSYGLSPSFSKDSEDFSHGLNERTRLSNIRPGITYYLTLITDLTK

Sequences:

>Translated_467_residues
MKLKSLFHLSIVSSLALVGAASAKDAAYPRAEAQTLDLAQKAIAIRSVRGEGNRTIDVANLFRDALLKGGWQVGDIEVTP
VDDTAYIIATWKGSDPSLKPVVISGHMDVVEAKREDWERDPFVPVVENGILYGRGASDMKFDGALALSTLIELRRQGFKP
KRTIVIEFSGDEETTMKTSAIIAEKLKNAELVINVDGGGGTLDEATGKPLYWTWQGAEKTYADYRLEVTNPGGHSSAPRP
DNAIVQLSQALVKVGAYRFKAEQNDITRGYFEKAAPFTDRPEIAAAMRAFAANPADEKALATLRADPSMVGKVGTTCVPT
MLGGGHAENALPQRAFANINCRIFPGHTKEAIMAELAQVVGDPAVKISDVTEGSVASPASPLRPDLMKAVTRAMTKAYPK
VPLIPSQASGASDSMWFRALGVPSYGLSPSFSKDSEDFSHGLNERTRLSNIRPGITYYLTLITDLTK
>Mature_467_residues
MKLKSLFHLSIVSSLALVGAASAKDAAYPRAEAQTLDLAQKAIAIRSVRGEGNRTIDVANLFRDALLKGGWQVGDIEVTP
VDDTAYIIATWKGSDPSLKPVVISGHMDVVEAKREDWERDPFVPVVENGILYGRGASDMKFDGALALSTLIELRRQGFKP
KRTIVIEFSGDEETTMKTSAIIAEKLKNAELVINVDGGGGTLDEATGKPLYWTWQGAEKTYADYRLEVTNPGGHSSAPRP
DNAIVQLSQALVKVGAYRFKAEQNDITRGYFEKAAPFTDRPEIAAAMRAFAANPADEKALATLRADPSMVGKVGTTCVPT
MLGGGHAENALPQRAFANINCRIFPGHTKEAIMAELAQVVGDPAVKISDVTEGSVASPASPLRPDLMKAVTRAMTKAYPK
VPLIPSQASGASDSMWFRALGVPSYGLSPSFSKDSEDFSHGLNERTRLSNIRPGITYYLTLITDLTK

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Homo sapiens, GI269846968, Length=393, Percent_Identity=27.4809160305344, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4501901, Length=457, Percent_Identity=23.6323851203501, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71982082, Length=424, Percent_Identity=27.8301886792453, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538642, Length=418, Percent_Identity=26.555023923445, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71982085, Length=438, Percent_Identity=27.3972602739726, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17538640, Length=419, Percent_Identity=26.491646778043, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71982710, Length=420, Percent_Identity=26.1904761904762, Blast_Score=76, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322289, Length=273, Percent_Identity=27.1062271062271, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21356353, Length=349, Percent_Identity=25.5014326647564, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24649206, Length=382, Percent_Identity=23.5602094240838, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24649212, Length=393, Percent_Identity=26.2086513994911, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24649208, Length=400, Percent_Identity=25.25, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24649210, Length=394, Percent_Identity=25.3807106598985, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24649202, Length=397, Percent_Identity=24.4332493702771, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24649204, Length=397, Percent_Identity=24.4332493702771, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 50312; Mature: 50312

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKSLFHLSIVSSLALVGAASAKDAAYPRAEAQTLDLAQKAIAIRSVRGEGNRTIDVAN
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHH
LFRDALLKGGWQVGDIEVTPVDDTAYIIATWKGSDPSLKPVVISGHMDVVEAKREDWERD
HHHHHHHHCCCEECCEEEEECCCCEEEEEEEECCCCCCCCEEEECCHHHHHHHHHCCCCC
PFVPVVENGILYGRGASDMKFDGALALSTLIELRRQGFKPKRTIVIEFSGDEETTMKTSA
CCCEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHH
IIAEKLKNAELVINVDGGGGTLDEATGKPLYWTWQGAEKTYADYRLEVTNPGGHSSAPRP
HHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCC
DNAIVQLSQALVKVGAYRFKAEQNDITRGYFEKAAPFTDRPEIAAAMRAFAANPADEKAL
CHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHH
ATLRADPSMVGKVGTTCVPTMLGGGHAENALPQRAFANINCRIFPGHTKEAIMAELAQVV
HHHCCCHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHCCCEEEEECCCCHHHHHHHHHHHH
GDPAVKISDVTEGSVASPASPLRPDLMKAVTRAMTKAYPKVPLIPSQASGASDSMWFRAL
CCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEE
GVPSYGLSPSFSKDSEDFSHGLNERTRLSNIRPGITYYLTLITDLTK
CCCCCCCCCCCCCCCHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKLKSLFHLSIVSSLALVGAASAKDAAYPRAEAQTLDLAQKAIAIRSVRGEGNRTIDVAN
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHH
LFRDALLKGGWQVGDIEVTPVDDTAYIIATWKGSDPSLKPVVISGHMDVVEAKREDWERD
HHHHHHHHCCCEECCEEEEECCCCEEEEEEEECCCCCCCCEEEECCHHHHHHHHHCCCCC
PFVPVVENGILYGRGASDMKFDGALALSTLIELRRQGFKPKRTIVIEFSGDEETTMKTSA
CCCEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHH
IIAEKLKNAELVINVDGGGGTLDEATGKPLYWTWQGAEKTYADYRLEVTNPGGHSSAPRP
HHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCC
DNAIVQLSQALVKVGAYRFKAEQNDITRGYFEKAAPFTDRPEIAAAMRAFAANPADEKAL
CHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHH
ATLRADPSMVGKVGTTCVPTMLGGGHAENALPQRAFANINCRIFPGHTKEAIMAELAQVV
HHHCCCHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHCCCEEEEECCCCHHHHHHHHHHHH
GDPAVKISDVTEGSVASPASPLRPDLMKAVTRAMTKAYPKVPLIPSQASGASDSMWFRAL
CCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEE
GVPSYGLSPSFSKDSEDFSHGLNERTRLSNIRPGITYYLTLITDLTK
CCCCCCCCCCCCCCCHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]