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The map label for this gene is htxE [H]

Identifier: 87199568

GI number: 87199568

Start: 1606100

End: 1607053

Strand: Direct

Name: htxE [H]

Synonym: Saro_1551

Alternate gene names: 87199568

Gene position: 1606100-1607053 (Clockwise)

Preceding gene: 87199567

Following gene: 87199569

Centisome position: 45.1

GC content: 65.62

Gene sequence:

>954_bases
ATGACCTCTAGCGCGAACGCCCGCCCCATTTCGCGGCGTCTTGTGGTGATGCTTTCGCTCCTGATCTTTGCTGCGTTCAG
CGCCCCGCGCATGGACCTAGGCCGGATTGTTGCATTCGCGTCGGCAAGTCATCCGGGGGGCGGGGCACAGGCCGGCTTAC
AAGGGTTCAGGCCGCCACAGGTCGAAACGCGCGCTGCAGTGGCGGATCTGCCCGATCGCGATCCCGCCCGGCTTCCACCG
TTCGCCCGTATAGAGACTCAAACTATCCGCGAACGCCAGCTCGACCCTGAAACGCTCCAGCCCGTGGAGCGGGAAGTTCG
GCGCACATGGCTCGTATCCCCGTTTGGCTATCTCGCTGAGGTGGCGTTGCGTATGATCGAGACGATCGAGATCGCCCTGT
GGGGAACGCTGCTCGCGGTGCTGGTCGGGTTTCCGCTCGCCTTGCTGCGCGCTCGCGCCTTTAGCTTGCCCAGGCCGGTG
AGGATGCTGGCGAGGATGGTTTGCGCGGGGCTGCGGGCGCTTCCCGAATTGCTGGTCGCGCTCATTCTGGTGGGCCTGCT
GGGTTTTGGACCGCCAGCCGGTGTCTTCGCGCTGGGCATTCATGCGGCGGGCTTCATCGGGCGCTTCCATGCGGATGCCT
TCGATGACGCAGACCAGCGCCCCGTCGAGGCGCTGCGGGCGTCGGGCGCGGGAAGGTTCGCGGTGTTCCGGATCGCCGTG
CTGCCTCAGGTCCGTGCCAACCTCGCTTCCTCCACGCTCTATATCCTCGATCGCAACGTGCGCATGGCGACCGTGATCGG
GATCGTCGGTGCCGGCGGCATCGGCCAGGAGCTGAAGGGGCGTATCGACATGTACGATTACGGCCATGCCGCCACGATCG
TCCTCGCCATCTTCGCCGTCGTTGCGCTGCTCGACGAATTCGCCGCGCATCTGCGCCGCCGCCAGTCTTCTTGA

Upstream 100 bases:

>100_bases
TGCACCAGCCCGACCTTGCGGCGTCATTCGCCCAAAGGATCATTCATCTTCAGAAGGGCCGCATCGTCTCGGCCGACGGT
TCCGTCGGAAGAGACGCGGC

Downstream 100 bases:

>100_bases
TCCATCGCAGGAGTAGTACCACGATGTCCAACACAAGACGCGATTTCCTGAAATCCGCCGCAATCGGCGGGGTTGCAGGG
ACCCTTCCGGCCAGCATCGC

Product: phosphonate ABC transporter permease

Products: 3-phospho-serine [Cytoplasm]; phosphite [Cytoplasm]; ADP; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MTSSANARPISRRLVVMLSLLIFAAFSAPRMDLGRIVAFASASHPGGGAQAGLQGFRPPQVETRAAVADLPDRDPARLPP
FARIETQTIRERQLDPETLQPVEREVRRTWLVSPFGYLAEVALRMIETIEIALWGTLLAVLVGFPLALLRARAFSLPRPV
RMLARMVCAGLRALPELLVALILVGLLGFGPPAGVFALGIHAAGFIGRFHADAFDDADQRPVEALRASGAGRFAVFRIAV
LPQVRANLASSTLYILDRNVRMATVIGIVGAGGIGQELKGRIDMYDYGHAATIVLAIFAVVALLDEFAAHLRRRQSS

Sequences:

>Translated_317_residues
MTSSANARPISRRLVVMLSLLIFAAFSAPRMDLGRIVAFASASHPGGGAQAGLQGFRPPQVETRAAVADLPDRDPARLPP
FARIETQTIRERQLDPETLQPVEREVRRTWLVSPFGYLAEVALRMIETIEIALWGTLLAVLVGFPLALLRARAFSLPRPV
RMLARMVCAGLRALPELLVALILVGLLGFGPPAGVFALGIHAAGFIGRFHADAFDDADQRPVEALRASGAGRFAVFRIAV
LPQVRANLASSTLYILDRNVRMATVIGIVGAGGIGQELKGRIDMYDYGHAATIVLAIFAVVALLDEFAAHLRRRQSS
>Mature_316_residues
TSSANARPISRRLVVMLSLLIFAAFSAPRMDLGRIVAFASASHPGGGAQAGLQGFRPPQVETRAAVADLPDRDPARLPPF
ARIETQTIRERQLDPETLQPVEREVRRTWLVSPFGYLAEVALRMIETIEIALWGTLLAVLVGFPLALLRARAFSLPRPVR
MLARMVCAGLRALPELLVALILVGLLGFGPPAGVFALGIHAAGFIGRFHADAFDDADQRPVEALRASGAGRFAVFRIAVL
PQVRANLASSTLYILDRNVRMATVIGIVGAGGIGQELKGRIDMYDYGHAATIVLAIFAVVALLDEFAAHLRRRQSS

Specific function: Probably forms part of a binding-protein-dependent hypophosphite transporter [H]

COG id: COG3639

COG function: function code P; ABC-type phosphate/phosphonate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34228; Mature: 34096

Theoretical pI: Translated: 11.38; Mature: 11.38

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSANARPISRRLVVMLSLLIFAAFSAPRMDLGRIVAFASASHPGGGAQAGLQGFRPPQ
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHCCCCCCCCC
VETRAAVADLPDRDPARLPPFARIETQTIRERQLDPETLQPVEREVRRTWLVSPFGYLAE
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHH
VALRMIETIEIALWGTLLAVLVGFPLALLRARAFSLPRPVRMLARMVCAGLRALPELLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LILVGLLGFGPPAGVFALGIHAAGFIGRFHADAFDDADQRPVEALRASGAGRFAVFRIAV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHH
LPQVRANLASSTLYILDRNVRMATVIGIVGAGGIGQELKGRIDMYDYGHAATIVLAIFAV
HHHHHHHHHHCEEEEEECCCHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHH
VALLDEFAAHLRRRQSS
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSSANARPISRRLVVMLSLLIFAAFSAPRMDLGRIVAFASASHPGGGAQAGLQGFRPPQ
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHCCCCCCCCC
VETRAAVADLPDRDPARLPPFARIETQTIRERQLDPETLQPVEREVRRTWLVSPFGYLAE
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHH
VALRMIETIEIALWGTLLAVLVGFPLALLRARAFSLPRPVRMLARMVCAGLRALPELLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LILVGLLGFGPPAGVFALGIHAAGFIGRFHADAFDDADQRPVEALRASGAGRFAVFRIAV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHH
LPQVRANLASSTLYILDRNVRMATVIGIVGAGGIGQELKGRIDMYDYGHAATIVLAIFAV
HHHHHHHHHHCEEEEEECCCHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHH
VALLDEFAAHLRRRQSS
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]