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The map label for this gene is betA [H]

Identifier: 87199561

GI number: 87199561

Start: 1593855

End: 1595447

Strand: Direct

Name: betA [H]

Synonym: Saro_1543

Alternate gene names: 87199561

Gene position: 1593855-1595447 (Clockwise)

Preceding gene: 87199559

Following gene: 87199562

Centisome position: 44.75

GC content: 64.03

Gene sequence:

>1593_bases
GTGCGCAAGCATGAGGCATTCGACTATGTCATCGTTGGTGCCGGTTCGGCCGGTTGCGTCCTCGCAAACCGGCTATCGGC
CGATCCCGACGTGAGTGTCCTGGTACTCGAGGCGGGCGGGCGCGACACCAGTCCGTTCATCCACATGCCGGCGGGCTTCT
TCCAGTTGTTGCAGAGTGGCAGCAATGCCTGGCACTACCAGACGGCGCCGCAGGAGCACCTGAACGGCCGCGTACTTGCC
GACGCCCGAGGCAAGGTGCTGGGCGGCAGCAGTTCCATCAACGGCATGTGCTACAGCCGCGGCAGTCCCGAGATATTCGA
CCACTGGGCGGAACTCGGCAACGATGGCTGGTCATACAAAGACGTGCTGCCCTGGTTCCGCAAGGCCGAGGGCAACCCGG
GCGCCGATCCTTACTTCCACGGCCAGGATGGTCCCTTGTCCGTTACCCATGCTTCGGTCACCAACCCGGCGCAGTTGGCC
TGGCTTCGGGCTGCGCAGGAAGCAGGCTTTCCCTACAGCGACGACCACAACGGTGCCGCCCCGGAGGGCTTCGGGCCGGG
GGAACACACAATCCGCAACGGGCGGAGGATCAGCACGGCTGTCGCGTATCTCAAACCGGCGATGCGACGTCGCAACCTCG
TTGTACGAACTCGCGCGCATGCCACGCGGGTCTTGCTCGAGGGCGCGCGCGCAACAGGAGTGGAATATCGGCAGGGAAGG
GCGCTGCAGAAGGTCCACGCCAGTCGCGAAGTGATCCTTTGTGGTGGCACTTTCCAGTCGCCGCAATTGTTGATGCTGTC
GGGCATCGGAGACGGCGCACATCTTCAGCCGCTCGGTATACGTACGGTGGTCGACCTGAAAGGCGTGGGCCGCAACCTCC
ACGATCACATTGGCACGCAAGTCCAGATGACCTGCCCAGAGCCCGTGTCCGACTTCTCGGTAGCGACGAACCCGTTGCGG
ATGGCGCTGGCGGGCCTTCAGTATCTCGTCGCGCGCAAGGGGCCTCTGGCCCGGAGCGGAACCGACGTCGTTGCCTATCT
GCGCTCGGGCGCGCCCGGGCACGATGAACTCGATCTCAAGTTCTATTTCATCCCGCTGCTGTTCAACGAGGGTGGCGGCA
TTGCACGGCAGCATGGCTTCTCCAACCTGGTTATCCTGACCCGGCCCGAAAGTCGCGGGGAGCTGCGCCTCCGCTCTGCC
AACCCGGTGGATCAGCCGCTGATCGATTCGAATTACCTGGCGGAAGGGCGCGACCGCGATGCGCTGCGCCGCGGGGTTGG
CATTGTTCGCCGGATCTTTGCCCAGCCTGCGTTTGCCCGCTTTCGCGGCGTCGAATGCACGCCGGGCGCCGACATTGCCG
ATGACGTTGCGCTCGATGGCTTCTTCCGCGAGACCTGCAACGTCAATTACGAGGCCGTGGGCACCTGTCGGATGGGTGAT
GACGAACTCGCCGTGGTCGATCCGGGGTTGCGAGTTCGGGGTGTGGAAGGTCTTCGCGTCGTTGACGGGTCGGTAATGCC
CCGCATCACGACCGGGGACCCCAATGCGACGATCGTGATGATCGCGGAAAAGGCCGCACAGATGATCCTCTGA

Upstream 100 bases:

>100_bases
CTTGGGAGAGCGATTGGAATGAAGACCTTGTCACGCCTCGCACGCCGGGATTTCGGCCCGGCCTGCCCCGTCATCGGCGC
GCTCATGAGGGAGGTCAGCC

Downstream 100 bases:

>100_bases
TTAAATGCGGCGGCGCTCCCTGGTGACAGGGGCGCCACTAGCCGCGCGGTGTATGGGCTGGCCAGCCGTCCAGCTTTGCC
GGCGGAAAGTTTTCGTTGCG

Product: glucose-methanol-choline oxidoreductase

Products: NA

Alternate protein names: CDH; CHD [H]

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MRKHEAFDYVIVGAGSAGCVLANRLSADPDVSVLVLEAGGRDTSPFIHMPAGFFQLLQSGSNAWHYQTAPQEHLNGRVLA
DARGKVLGGSSSINGMCYSRGSPEIFDHWAELGNDGWSYKDVLPWFRKAEGNPGADPYFHGQDGPLSVTHASVTNPAQLA
WLRAAQEAGFPYSDDHNGAAPEGFGPGEHTIRNGRRISTAVAYLKPAMRRRNLVVRTRAHATRVLLEGARATGVEYRQGR
ALQKVHASREVILCGGTFQSPQLLMLSGIGDGAHLQPLGIRTVVDLKGVGRNLHDHIGTQVQMTCPEPVSDFSVATNPLR
MALAGLQYLVARKGPLARSGTDVVAYLRSGAPGHDELDLKFYFIPLLFNEGGGIARQHGFSNLVILTRPESRGELRLRSA
NPVDQPLIDSNYLAEGRDRDALRRGVGIVRRIFAQPAFARFRGVECTPGADIADDVALDGFFRETCNVNYEAVGTCRMGD
DELAVVDPGLRVRGVEGLRVVDGSVMPRITTGDPNATIVMIAEKAAQMIL

Sequences:

>Translated_530_residues
MRKHEAFDYVIVGAGSAGCVLANRLSADPDVSVLVLEAGGRDTSPFIHMPAGFFQLLQSGSNAWHYQTAPQEHLNGRVLA
DARGKVLGGSSSINGMCYSRGSPEIFDHWAELGNDGWSYKDVLPWFRKAEGNPGADPYFHGQDGPLSVTHASVTNPAQLA
WLRAAQEAGFPYSDDHNGAAPEGFGPGEHTIRNGRRISTAVAYLKPAMRRRNLVVRTRAHATRVLLEGARATGVEYRQGR
ALQKVHASREVILCGGTFQSPQLLMLSGIGDGAHLQPLGIRTVVDLKGVGRNLHDHIGTQVQMTCPEPVSDFSVATNPLR
MALAGLQYLVARKGPLARSGTDVVAYLRSGAPGHDELDLKFYFIPLLFNEGGGIARQHGFSNLVILTRPESRGELRLRSA
NPVDQPLIDSNYLAEGRDRDALRRGVGIVRRIFAQPAFARFRGVECTPGADIADDVALDGFFRETCNVNYEAVGTCRMGD
DELAVVDPGLRVRGVEGLRVVDGSVMPRITTGDPNATIVMIAEKAAQMIL
>Mature_530_residues
MRKHEAFDYVIVGAGSAGCVLANRLSADPDVSVLVLEAGGRDTSPFIHMPAGFFQLLQSGSNAWHYQTAPQEHLNGRVLA
DARGKVLGGSSSINGMCYSRGSPEIFDHWAELGNDGWSYKDVLPWFRKAEGNPGADPYFHGQDGPLSVTHASVTNPAQLA
WLRAAQEAGFPYSDDHNGAAPEGFGPGEHTIRNGRRISTAVAYLKPAMRRRNLVVRTRAHATRVLLEGARATGVEYRQGR
ALQKVHASREVILCGGTFQSPQLLMLSGIGDGAHLQPLGIRTVVDLKGVGRNLHDHIGTQVQMTCPEPVSDFSVATNPLR
MALAGLQYLVARKGPLARSGTDVVAYLRSGAPGHDELDLKFYFIPLLFNEGGGIARQHGFSNLVILTRPESRGELRLRSA
NPVDQPLIDSNYLAEGRDRDALRRGVGIVRRIFAQPAFARFRGVECTPGADIADDVALDGFFRETCNVNYEAVGTCRMGD
DELAVVDPGLRVRGVEGLRVVDGSVMPRITTGDPNATIVMIAEKAAQMIL

Specific function: Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=535, Percent_Identity=44.8598130841121, Blast_Score=422, Evalue=1e-118,
Organism=Escherichia coli, GI1786503, Length=534, Percent_Identity=42.5093632958801, Blast_Score=390, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17532301, Length=544, Percent_Identity=38.4191176470588, Blast_Score=363, Evalue=1e-100,
Organism=Drosophila melanogaster, GI45549471, Length=567, Percent_Identity=38.4479717813051, Blast_Score=318, Evalue=4e-87,
Organism=Drosophila melanogaster, GI45551458, Length=568, Percent_Identity=38.556338028169, Blast_Score=318, Evalue=6e-87,
Organism=Drosophila melanogaster, GI24642048, Length=572, Percent_Identity=37.0629370629371, Blast_Score=316, Evalue=2e-86,
Organism=Drosophila melanogaster, GI24642042, Length=569, Percent_Identity=35.3251318101933, Blast_Score=306, Evalue=3e-83,
Organism=Drosophila melanogaster, GI24642059, Length=568, Percent_Identity=36.2676056338028, Blast_Score=305, Evalue=4e-83,
Organism=Drosophila melanogaster, GI24642055, Length=577, Percent_Identity=35.528596187175, Blast_Score=298, Evalue=7e-81,
Organism=Drosophila melanogaster, GI24650267, Length=570, Percent_Identity=35.4385964912281, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24642039, Length=569, Percent_Identity=34.2706502636204, Blast_Score=284, Evalue=1e-76,
Organism=Drosophila melanogaster, GI18859995, Length=561, Percent_Identity=34.9376114081996, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24642035, Length=572, Percent_Identity=35.4895104895105, Blast_Score=275, Evalue=5e-74,
Organism=Drosophila melanogaster, GI17137792, Length=551, Percent_Identity=35.02722323049, Blast_Score=275, Evalue=6e-74,
Organism=Drosophila melanogaster, GI24642037, Length=567, Percent_Identity=36.1552028218695, Blast_Score=268, Evalue=7e-72,
Organism=Drosophila melanogaster, GI24642051, Length=574, Percent_Identity=34.4947735191638, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI18859993, Length=580, Percent_Identity=33.6206896551724, Blast_Score=241, Evalue=6e-64,
Organism=Drosophila melanogaster, GI24645930, Length=590, Percent_Identity=31.864406779661, Blast_Score=179, Evalue=5e-45,
Organism=Drosophila melanogaster, GI24642057, Length=585, Percent_Identity=32.1367521367521, Blast_Score=157, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011533
- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.1 [H]

Molecular weight: Translated: 57317; Mature: 57317

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00623 GMC_OXRED_1 ; PS00624 GMC_OXRED_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKHEAFDYVIVGAGSAGCVLANRLSADPDVSVLVLEAGGRDTSPFIHMPAGFFQLLQSG
CCCCCCCCEEEEECCCCCEEEECCCCCCCCCEEEEEECCCCCCCCEEECCHHHHHHHHCC
SNAWHYQTAPQEHLNGRVLADARGKVLGGSSSINGMCYSRGSPEIFDHWAELGNDGWSYK
CCCEEECCCCHHHCCCEEEECCCCCEECCCCCCCCEEECCCCCHHHHHHHHHCCCCCCHH
DVLPWFRKAEGNPGADPYFHGQDGPLSVTHASVTNPAQLAWLRAAQEAGFPYSDDHNGAA
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
PEGFGPGEHTIRNGRRISTAVAYLKPAMRRRNLVVRTRAHATRVLLEGARATGVEYRQGR
CCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHCCCCCCCCHHCCH
ALQKVHASREVILCGGTFQSPQLLMLSGIGDGAHLQPLGIRTVVDLKGVGRNLHDHIGTQ
HHHHHHCCCEEEEECCCCCCCCEEEEECCCCCCEECCCCCEEEEEHHHCCCCHHHHCCCE
VQMTCPEPVSDFSVATNPLRMALAGLQYLVARKGPLARSGTDVVAYLRSGAPGHDELDLK
EEEECCCCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCEEEE
FYFIPLLFNEGGGIARQHGFSNLVILTRPESRGELRLRSANPVDQPLIDSNYLAEGRDRD
EEEEEEEEECCCCCHHHCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHH
ALRRGVGIVRRIFAQPAFARFRGVECTPGADIADDVALDGFFRETCNVNYEAVGTCRMGD
HHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCC
DELAVVDPGLRVRGVEGLRVVDGSVMPRITTGDPNATIVMIAEKAAQMIL
CCEEEECCCCEEECCCCEEEECCCCCCEEECCCCCEEEEEEECHHHHHCC
>Mature Secondary Structure
MRKHEAFDYVIVGAGSAGCVLANRLSADPDVSVLVLEAGGRDTSPFIHMPAGFFQLLQSG
CCCCCCCCEEEEECCCCCEEEECCCCCCCCCEEEEEECCCCCCCCEEECCHHHHHHHHCC
SNAWHYQTAPQEHLNGRVLADARGKVLGGSSSINGMCYSRGSPEIFDHWAELGNDGWSYK
CCCEEECCCCHHHCCCEEEECCCCCEECCCCCCCCEEECCCCCHHHHHHHHHCCCCCCHH
DVLPWFRKAEGNPGADPYFHGQDGPLSVTHASVTNPAQLAWLRAAQEAGFPYSDDHNGAA
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
PEGFGPGEHTIRNGRRISTAVAYLKPAMRRRNLVVRTRAHATRVLLEGARATGVEYRQGR
CCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHCCCCCCCCHHCCH
ALQKVHASREVILCGGTFQSPQLLMLSGIGDGAHLQPLGIRTVVDLKGVGRNLHDHIGTQ
HHHHHHCCCEEEEECCCCCCCCEEEEECCCCCCEECCCCCEEEEEHHHCCCCHHHHCCCE
VQMTCPEPVSDFSVATNPLRMALAGLQYLVARKGPLARSGTDVVAYLRSGAPGHDELDLK
EEEECCCCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCEEEE
FYFIPLLFNEGGGIARQHGFSNLVILTRPESRGELRLRSANPVDQPLIDSNYLAEGRDRD
EEEEEEEEECCCCCHHHCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHH
ALRRGVGIVRRIFAQPAFARFRGVECTPGADIADDVALDGFFRETCNVNYEAVGTCRMGD
HHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCC
DELAVVDPGLRVRGVEGLRVVDGSVMPRITTGDPNATIVMIAEKAAQMIL
CCEEEECCCCEEECCCCEEEECCCCCCEEECCCCCEEEEEEECHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]