Click here to switch to the map view.

The map label for this gene is yjjL [H]

Identifier: 87199553

GI number: 87199553

Start: 1580914

End: 1582263

Strand: Direct

Name: yjjL [H]

Synonym: Saro_1535

Alternate gene names: 87199553

Gene position: 1580914-1582263 (Clockwise)

Preceding gene: 87199551

Following gene: 87199554

Centisome position: 44.39

GC content: 61.11

Gene sequence:

>1350_bases
ATGACCGGCGATACCATGATTGCTCCCACTGAAGTCCCGCCTTCGCGGATGCCTTATGGTGCCCTCTGCCTGTTGATGGT
GGTCTATGCGTTCAACATGCTGGATCGGCAGATAGTGACCATCCTCGTAGAGGCGATAAAGGCTGATCTTGGTCTTGCAG
ACTGGCAGATCGGGATTATCAGCGGCCTCGCCTTTGCGATCTTTTACACCTTGCTTGGCATACCGCTCGCACGGATCGCG
GACCGCGGAAACCGGGTTGGAATGATCGCGGTCTCTTTGACTGTCTGGAGCGGCTTCACTGCGCTGTGCGGGTTCTCGCG
CAATTTTGTCGAGTTGCTTGTCGCACGCGTCGGTGTCGGCGTTGGCGAAGCAGGATGCACTCCTGCTGCGCACAGCCTCA
TCACGGATTATGTCGCACGCGCGCAACGCGGCCGAGCACTCGCCCTTTATTCGTTGGGCGTGCCGATCGGCTCGCTCGCT
GGCCTTGTTCTCGGCGGTATATTGCTGGCCACTCTGGGTTGGCGATCCGCTTTCGTGATTGCCGGTCTGCCCGGGATTAT
CCTGGCGGTGATCGTCTGGTATGCACTTGAAGAGCCGCGCAAACATTTGGTCGCGGCCCGGGAAACGGGGCCTGCGCACA
TACCGCTGGCACAAGCTCTCGCTACTTTGCGTCGATTGCCAAGCTTTTGGTTGGTCTCGCTTGGCACCGCAATGGCTGCC
TTCGGCTACTACGGCCAGTCGTCGTTTTTCGCTTCGCTCTACCTGCGCACGCATGGAGCAGGGATCGATGAAATGGCCAT
GGGTCACGATATGTCGCCAACTGTGTTCCTGGGGCTGAGCCTGGGATTCATCGTCGGAATCGTGGGTATGGCCGGCACCT
TTGTCGGCGGACTTCTGGCGGATCTGGCCGCGCGGGGCGGGGTCAAGGGCTATACGGTAGTTCCGGCGACTTCGCTCATC
CTGGCGGCACCGCTATTTGCGGCTGCGGCGCTTGCCAATACGGTCGCACTGTCCTTCGCGTTTCTCAGCTGTGCAATCTT
CGTCCACGCGCTCAACTACGGTTCGGTCTTTGCTTCTGTGCAGACCCTTGTTCCCGCAAGGTTGCGCGCGATGGCGGCCG
CGCTGCAGTTGTTCGTGACAAACGCGATTGGCCTCGCGCTTGGCCCGCTGTTCGTGGGCCTTGCTAGTGACCTGCTGGGC
TCCATGCTCGGCAAGGAGCAGGGCTTGCGTGTCGCGATGGCGCTAGTCGTGCTACCGCTGGCGGTCGGGGCCGCATTTTT
CTGGGCTGCGAGCCGCCGGATCGATGCCGACGAGGCTCTAGGTGCGCGTCTGGGGGCCGCCCTCCCTTAA

Upstream 100 bases:

>100_bases
ATTGTTGCTCCGCTTCGGATGCCTCCGCCTGCAAATCACGGCCGGACGCCTAGGTTGCCGCCTCGCATGTAAGGGCAACA
AGCCCGTCACGGAGAGGCTG

Downstream 100 bases:

>100_bases
TTTGAAAAGTGGCCGCATGCATCTCCGCTTCCCGTTCGTGGCCCGGCGGGAAGGATTTTCTGCTTGAGCAGGGCGCGCTT
GAAGCTCGGGTGCTGCAGGG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MTGDTMIAPTEVPPSRMPYGALCLLMVVYAFNMLDRQIVTILVEAIKADLGLADWQIGIISGLAFAIFYTLLGIPLARIA
DRGNRVGMIAVSLTVWSGFTALCGFSRNFVELLVARVGVGVGEAGCTPAAHSLITDYVARAQRGRALALYSLGVPIGSLA
GLVLGGILLATLGWRSAFVIAGLPGIILAVIVWYALEEPRKHLVAARETGPAHIPLAQALATLRRLPSFWLVSLGTAMAA
FGYYGQSSFFASLYLRTHGAGIDEMAMGHDMSPTVFLGLSLGFIVGIVGMAGTFVGGLLADLAARGGVKGYTVVPATSLI
LAAPLFAAAALANTVALSFAFLSCAIFVHALNYGSVFASVQTLVPARLRAMAAALQLFVTNAIGLALGPLFVGLASDLLG
SMLGKEQGLRVAMALVVLPLAVGAAFFWAASRRIDADEALGARLGAALP

Sequences:

>Translated_449_residues
MTGDTMIAPTEVPPSRMPYGALCLLMVVYAFNMLDRQIVTILVEAIKADLGLADWQIGIISGLAFAIFYTLLGIPLARIA
DRGNRVGMIAVSLTVWSGFTALCGFSRNFVELLVARVGVGVGEAGCTPAAHSLITDYVARAQRGRALALYSLGVPIGSLA
GLVLGGILLATLGWRSAFVIAGLPGIILAVIVWYALEEPRKHLVAARETGPAHIPLAQALATLRRLPSFWLVSLGTAMAA
FGYYGQSSFFASLYLRTHGAGIDEMAMGHDMSPTVFLGLSLGFIVGIVGMAGTFVGGLLADLAARGGVKGYTVVPATSLI
LAAPLFAAAALANTVALSFAFLSCAIFVHALNYGSVFASVQTLVPARLRAMAAALQLFVTNAIGLALGPLFVGLASDLLG
SMLGKEQGLRVAMALVVLPLAVGAAFFWAASRRIDADEALGARLGAALP
>Mature_448_residues
TGDTMIAPTEVPPSRMPYGALCLLMVVYAFNMLDRQIVTILVEAIKADLGLADWQIGIISGLAFAIFYTLLGIPLARIAD
RGNRVGMIAVSLTVWSGFTALCGFSRNFVELLVARVGVGVGEAGCTPAAHSLITDYVARAQRGRALALYSLGVPIGSLAG
LVLGGILLATLGWRSAFVIAGLPGIILAVIVWYALEEPRKHLVAARETGPAHIPLAQALATLRRLPSFWLVSLGTAMAAF
GYYGQSSFFASLYLRTHGAGIDEMAMGHDMSPTVFLGLSLGFIVGIVGMAGTFVGGLLADLAARGGVKGYTVVPATSLIL
AAPLFAAAALANTVALSFAFLSCAIFVHALNYGSVFASVQTLVPARLRAMAAALQLFVTNAIGLALGPLFVGLASDLLGS
MLGKEQGLRVAMALVVLPLAVGAAFFWAASRRIDADEALGARLGAALP

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI215490096, Length=432, Percent_Identity=26.3888888888889, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI14042968, Length=432, Percent_Identity=26.3888888888889, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI215490100, Length=420, Percent_Identity=26.4285714285714, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI194239645, Length=461, Percent_Identity=25.1626898047722, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI185136021, Length=432, Percent_Identity=24.3055555555556, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI2367379, Length=403, Percent_Identity=25.5583126550869, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI87082320, Length=189, Percent_Identity=26.4550264550265, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789152, Length=190, Percent_Identity=26.8421052631579, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71992409, Length=447, Percent_Identity=25.2796420581655, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17557872, Length=392, Percent_Identity=21.9387755102041, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193209775, Length=421, Percent_Identity=22.5653206650831, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17539092, Length=419, Percent_Identity=21.9570405727924, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24654039, Length=420, Percent_Identity=24.7619047619048, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17864456, Length=420, Percent_Identity=24.7619047619048, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24654041, Length=417, Percent_Identity=25.1798561151079, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24654037, Length=417, Percent_Identity=25.1798561151079, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24640209, Length=356, Percent_Identity=25.8426966292135, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24654044, Length=274, Percent_Identity=24.8175182481752, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46620; Mature: 46489

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGDTMIAPTEVPPSRMPYGALCLLMVVYAFNMLDRQIVTILVEAIKADLGLADWQIGII
CCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SGLAFAIFYTLLGIPLARIADRGNRVGMIAVSLTVWSGFTALCGFSRNFVELLVARVGVG
HHHHHHHHHHHHHCHHHHHHCCCCCEEEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHCCC
VGEAGCTPAAHSLITDYVARAQRGRALALYSLGVPIGSLAGLVLGGILLATLGWRSAFVI
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AGLPGIILAVIVWYALEEPRKHLVAARETGPAHIPLAQALATLRRLPSFWLVSLGTAMAA
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
FGYYGQSSFFASLYLRTHGAGIDEMAMGHDMSPTVFLGLSLGFIVGIVGMAGTFVGGLLA
HHHCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLAARGGVKGYTVVPATSLILAAPLFAAAALANTVALSFAFLSCAIFVHALNYGSVFASV
HHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTLVPARLRAMAAALQLFVTNAIGLALGPLFVGLASDLLGSMLGKEQGLRVAMALVVLPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
AVGAAFFWAASRRIDADEALGARLGAALP
HHHHHHHHHHHCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
TGDTMIAPTEVPPSRMPYGALCLLMVVYAFNMLDRQIVTILVEAIKADLGLADWQIGII
CCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SGLAFAIFYTLLGIPLARIADRGNRVGMIAVSLTVWSGFTALCGFSRNFVELLVARVGVG
HHHHHHHHHHHHHCHHHHHHCCCCCEEEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHCCC
VGEAGCTPAAHSLITDYVARAQRGRALALYSLGVPIGSLAGLVLGGILLATLGWRSAFVI
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AGLPGIILAVIVWYALEEPRKHLVAARETGPAHIPLAQALATLRRLPSFWLVSLGTAMAA
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
FGYYGQSSFFASLYLRTHGAGIDEMAMGHDMSPTVFLGLSLGFIVGIVGMAGTFVGGLLA
HHHCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLAARGGVKGYTVVPATSLILAAPLFAAAALANTVALSFAFLSCAIFVHALNYGSVFASV
HHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTLVPARLRAMAAALQLFVTNAIGLALGPLFVGLASDLLGSMLGKEQGLRVAMALVVLPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
AVGAAFFWAASRRIDADEALGARLGAALP
HHHHHHHHHHHCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]