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The map label for this gene is xylR [H]

Identifier: 87199513

GI number: 87199513

Start: 1536757

End: 1538481

Strand: Reverse

Name: xylR [H]

Synonym: Saro_1494

Alternate gene names: 87199513

Gene position: 1538481-1536757 (Counterclockwise)

Preceding gene: 87199515

Following gene: 87199512

Centisome position: 43.2

GC content: 58.43

Gene sequence:

>1725_bases
ATGAGAGAGGATCTGGAAGTGGCAAGAGGGGACGTTCATGACCAGATTCCGCAGGCCCCGGCGTTTGACGACCTGCGCAA
GTCGCTGCATTTCATGCCGGACGAGGCCTCGATCTGGCTAGACGGCCGCCGCATGATCCTTACCGAACATGATGCACAAG
GCATCATGCGCCGCGAACTGATTGTCGCGGTTGGACTTGAACGTGCCCGCGCGATCATGACGCGGCTTGGCTACGAACTT
GGCGCGGTCGAAGCGGAACTGGCAATTCGCCTTCGCAAGGATACGTCGGTGTTCAACGCCTTTTCGGCTGGGCCGCAACT
TCACGCACTCAAGGGCGTGGTCAAGGTCGAGCCGATCATATTCGACGTGGAGCCCGAAAAGGGGCGGTTCTACACCGAGT
ATTATTGGCGCCATTCCGCAGAATGCGAGAGCCACCTCGCCCACATGGGTGTCGGCCATCAACCCGGCGGATGGCAACAG
GTTGGATATGCGTCGGGCTATGCTTCAGCCTTCTTCGGCAGACCATTCGTGTTCCGGGAGATCGAGTGCGTAGCCATGGG
GCACAGCAAGTGCTTCCTGATCGGAAAGCCAGCTGAAGAATGGCACGAGCCTGAACGCGAGCTGCGCTATTTTCGCGCCG
AGAACTATTCCACACGTCCCAATACATCAGAAAAGGCACAAATTGTTCCCGACGGAGATCTGCGCATCGGCGCCCGCTCG
ATCGTCGGCGCATCTGCAGCCTTCAACATCGTCTTCAACCTGATCGACAAGGTCGCGCCCACCAACGCCCCAGTGCTTTT
CCTTGGCGAAAGCGGTGTCGGCAAGGAAGTGTTTGCACGCGAACTGCACAAACGCAGTACGCGCGCCGACAAGCATATGA
TCGCGATCAATTGCGCGGCGATCCCGGAAAACCTTGTCGAGGCCGAACTTTTCGGGGTGGAAAAGGGTGCGTTCACAGGC
GCAGTCGCGACGCGACCAGGCCGCTTTGAACGCGCGAATGGAGGCACGCTGTTTCTCGATGAAATCGGAACCCTGACCCT
GTCCGCACAGGGTAAATTGCTGCGCGTACTTCAGGAAGGCGAATTCGAGCGTGTCGGAGGCCGAGCGCCGCTGACCGCGA
ATGTGCGGATCATTGCCGCCACCAATGCAAATCTGCGGGACGAGATCAAGGCTGGACGCTTCCGCGCCGACCTGTTTCAC
CGGCTAAACGTGTTTCCTGTGCGAATTGCTCCGCTGCGGGAAAGGCGCGCGGATATTCCTCTGCTGATCAACCACTTCCA
GCGCCGGTTTGCGCAGCAACACGGCAAGACGCTGAAGGCCTTTTCGCAGGACGTGTTGCGCGCGTTCATGTCGTATGACT
GGCCAGGCAACGTCCGTGAACTGGAGAACATCGTTGAGCGCGGGGTGATCCTGGCAGACGAGGGCCTGCCGATCGACGTT
CACCACCTCATGACCGAAGCAGACCGCGACGAAGATGGCGAAGGCGGCGATCCATTCCGCGCCTACCTGCTCGACCGACC
TGATCCATCGGCGTCAAATAGCGCACTTGGAGGCAAGATGCTCGAAAGTGGCTTGGGTGCTGATGGCGCAATATCCGCAA
TGATCCGTGAGGCGCTTTTACGAACCAGCGGAAATGTATCAGAGACCGCTCGATTGACCGGCATGACGCGTTCACAAATA
AACTACTGGATAAGGCGCAATCGAAAGGTCGATGTCGAATTTTGA

Upstream 100 bases:

>100_bases
TCTTGACGGCAGCAGCGGAGCAAGGTGTCTTGGCCAGCACAACAAGACGAGGGCCGACGTGCATTGCACCCGGACCAATT
GAACTCCCTCGCGAACCATA

Downstream 100 bases:

>100_bases
ACATTCCGCCCCGAAATGATGTTCATTAACAAACACGCATCGTCCCTCTTGTCGCGGCAGAATTCTTAAAAACGGCGAAA
ATCTGCCAAAAACCGCATTT

Product: Fis family transcriptional regulator

Products: NA

Alternate protein names: 67 kDa protein [H]

Number of amino acids: Translated: 574; Mature: 574

Protein sequence:

>574_residues
MREDLEVARGDVHDQIPQAPAFDDLRKSLHFMPDEASIWLDGRRMILTEHDAQGIMRRELIVAVGLERARAIMTRLGYEL
GAVEAELAIRLRKDTSVFNAFSAGPQLHALKGVVKVEPIIFDVEPEKGRFYTEYYWRHSAECESHLAHMGVGHQPGGWQQ
VGYASGYASAFFGRPFVFREIECVAMGHSKCFLIGKPAEEWHEPERELRYFRAENYSTRPNTSEKAQIVPDGDLRIGARS
IVGASAAFNIVFNLIDKVAPTNAPVLFLGESGVGKEVFARELHKRSTRADKHMIAINCAAIPENLVEAELFGVEKGAFTG
AVATRPGRFERANGGTLFLDEIGTLTLSAQGKLLRVLQEGEFERVGGRAPLTANVRIIAATNANLRDEIKAGRFRADLFH
RLNVFPVRIAPLRERRADIPLLINHFQRRFAQQHGKTLKAFSQDVLRAFMSYDWPGNVRELENIVERGVILADEGLPIDV
HHLMTEADRDEDGEGGDPFRAYLLDRPDPSASNSALGGKMLESGLGADGAISAMIREALLRTSGNVSETARLTGMTRSQI
NYWIRRNRKVDVEF

Sequences:

>Translated_574_residues
MREDLEVARGDVHDQIPQAPAFDDLRKSLHFMPDEASIWLDGRRMILTEHDAQGIMRRELIVAVGLERARAIMTRLGYEL
GAVEAELAIRLRKDTSVFNAFSAGPQLHALKGVVKVEPIIFDVEPEKGRFYTEYYWRHSAECESHLAHMGVGHQPGGWQQ
VGYASGYASAFFGRPFVFREIECVAMGHSKCFLIGKPAEEWHEPERELRYFRAENYSTRPNTSEKAQIVPDGDLRIGARS
IVGASAAFNIVFNLIDKVAPTNAPVLFLGESGVGKEVFARELHKRSTRADKHMIAINCAAIPENLVEAELFGVEKGAFTG
AVATRPGRFERANGGTLFLDEIGTLTLSAQGKLLRVLQEGEFERVGGRAPLTANVRIIAATNANLRDEIKAGRFRADLFH
RLNVFPVRIAPLRERRADIPLLINHFQRRFAQQHGKTLKAFSQDVLRAFMSYDWPGNVRELENIVERGVILADEGLPIDV
HHLMTEADRDEDGEGGDPFRAYLLDRPDPSASNSALGGKMLESGLGADGAISAMIREALLRTSGNVSETARLTGMTRSQI
NYWIRRNRKVDVEF
>Mature_574_residues
MREDLEVARGDVHDQIPQAPAFDDLRKSLHFMPDEASIWLDGRRMILTEHDAQGIMRRELIVAVGLERARAIMTRLGYEL
GAVEAELAIRLRKDTSVFNAFSAGPQLHALKGVVKVEPIIFDVEPEKGRFYTEYYWRHSAECESHLAHMGVGHQPGGWQQ
VGYASGYASAFFGRPFVFREIECVAMGHSKCFLIGKPAEEWHEPERELRYFRAENYSTRPNTSEKAQIVPDGDLRIGARS
IVGASAAFNIVFNLIDKVAPTNAPVLFLGESGVGKEVFARELHKRSTRADKHMIAINCAAIPENLVEAELFGVEKGAFTG
AVATRPGRFERANGGTLFLDEIGTLTLSAQGKLLRVLQEGEFERVGGRAPLTANVRIIAATNANLRDEIKAGRFRADLFH
RLNVFPVRIAPLRERRADIPLLINHFQRRFAQQHGKTLKAFSQDVLRAFMSYDWPGNVRELENIVERGVILADEGLPIDV
HHLMTEADRDEDGEGGDPFRAYLLDRPDPSASNSALGGKMLESGLGADGAISAMIREALLRTSGNVSETARLTGMTRSQI
NYWIRRNRKVDVEF

Specific function: Regulatory protein of the TOL plasmid xyl operons. In the presence of m-xylene or m-methylbenzyl alcohol xylR activates both the xylCMABN operon and the regulatory gene xylS; xylS itself activates the xylXYZLTEGFJQKIH operon. XylR interacts with sigma- 54

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082117, Length=246, Percent_Identity=52.4390243902439, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI1790437, Length=231, Percent_Identity=51.5151515151515, Blast_Score=243, Evalue=3e-65,
Organism=Escherichia coli, GI1789087, Length=232, Percent_Identity=49.1379310344828, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI1790299, Length=328, Percent_Identity=43.2926829268293, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1788550, Length=231, Percent_Identity=49.7835497835498, Blast_Score=231, Evalue=6e-62,
Organism=Escherichia coli, GI87082152, Length=232, Percent_Identity=48.7068965517241, Blast_Score=222, Evalue=6e-59,
Organism=Escherichia coli, GI1789233, Length=240, Percent_Identity=47.0833333333333, Blast_Score=218, Evalue=1e-57,
Organism=Escherichia coli, GI87081872, Length=231, Percent_Identity=47.6190476190476, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1788905, Length=310, Percent_Identity=40, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1786524, Length=251, Percent_Identity=43.4262948207171, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1787583, Length=234, Percent_Identity=41.025641025641, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1789828, Length=244, Percent_Identity=34.8360655737705, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI87081858, Length=241, Percent_Identity=34.8547717842324, Blast_Score=132, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR004096
- InterPro:   IPR010523
- ProDom:   PD485437 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat; PF02830 V4R; PF06505 XylR_N [H]

EC number: NA

Molecular weight: Translated: 64053; Mature: 64053

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREDLEVARGDVHDQIPQAPAFDDLRKSLHFMPDEASIWLDGRRMILTEHDAQGIMRREL
CCCCHHHHCCCHHHHCCCCCCHHHHHHHHCCCCCCCEEEECCCEEEEEECCHHHHHHHHH
IVAVGLERARAIMTRLGYELGAVEAELAIRLRKDTSVFNAFSAGPQLHALKGVVKVEPII
HHHHHHHHHHHHHHHHCHHHCCEEEEEEEEEECCCHHHHHHCCCCCHHHHHCEEEECEEE
FDVEPEKGRFYTEYYWRHSAECESHLAHMGVGHQPGGWQQVGYASGYASAFFGRPFVFRE
EEECCCCCCEEEHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCHHEE
IECVAMGHSKCFLIGKPAEEWHEPERELRYFRAENYSTRPNTSEKAQIVPDGDLRIGARS
EEEEEECCCEEEEECCCHHHHHCCHHHHHHHHCCCCCCCCCCCCCCEECCCCCCEECHHH
IVGASAAFNIVFNLIDKVAPTNAPVLFLGESGVGKEVFARELHKRSTRADKHMIAINCAA
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEECC
IPENLVEAELFGVEKGAFTGAVATRPGRFERANGGTLFLDEIGTLTLSAQGKLLRVLQEG
CCHHHHHHHHHCCCCCCCCCEEECCCCCCEECCCCEEEEECCCEEEEECCCHHHHHHHCC
EFERVGGRAPLTANVRIIAATNANLRDEIKAGRFRADLFHRLNVFPVRIAPLRERRADIP
CHHHCCCCCCEEECEEEEEECCCCHHHHHHHCHHHHHHHHHCCEEEEEEECHHHHCCCCC
LLINHFQRRFAQQHGKTLKAFSQDVLRAFMSYDWPGNVRELENIVERGVILADEGLPIDV
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEECCCCCCHH
HHLMTEADRDEDGEGGDPFRAYLLDRPDPSASNSALGGKMLESGLGADGAISAMIREALL
HHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHH
RTSGNVSETARLTGMTRSQINYWIRRNRKVDVEF
HCCCCHHHHHHHHCCHHHHHHHHHHCCCEEECCC
>Mature Secondary Structure
MREDLEVARGDVHDQIPQAPAFDDLRKSLHFMPDEASIWLDGRRMILTEHDAQGIMRREL
CCCCHHHHCCCHHHHCCCCCCHHHHHHHHCCCCCCCEEEECCCEEEEEECCHHHHHHHHH
IVAVGLERARAIMTRLGYELGAVEAELAIRLRKDTSVFNAFSAGPQLHALKGVVKVEPII
HHHHHHHHHHHHHHHHCHHHCCEEEEEEEEEECCCHHHHHHCCCCCHHHHHCEEEECEEE
FDVEPEKGRFYTEYYWRHSAECESHLAHMGVGHQPGGWQQVGYASGYASAFFGRPFVFRE
EEECCCCCCEEEHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCHHEE
IECVAMGHSKCFLIGKPAEEWHEPERELRYFRAENYSTRPNTSEKAQIVPDGDLRIGARS
EEEEEECCCEEEEECCCHHHHHCCHHHHHHHHCCCCCCCCCCCCCCEECCCCCCEECHHH
IVGASAAFNIVFNLIDKVAPTNAPVLFLGESGVGKEVFARELHKRSTRADKHMIAINCAA
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEECC
IPENLVEAELFGVEKGAFTGAVATRPGRFERANGGTLFLDEIGTLTLSAQGKLLRVLQEG
CCHHHHHHHHHCCCCCCCCCEEECCCCCCEECCCCEEEEECCCEEEEECCCHHHHHHHCC
EFERVGGRAPLTANVRIIAATNANLRDEIKAGRFRADLFHRLNVFPVRIAPLRERRADIP
CHHHCCCCCCEEECEEEEEECCCCHHHHHHHCHHHHHHHHHCCEEEEEEECHHHHCCCCC
LLINHFQRRFAQQHGKTLKAFSQDVLRAFMSYDWPGNVRELENIVERGVILADEGLPIDV
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEECCCCCCHH
HHLMTEADRDEDGEGGDPFRAYLLDRPDPSASNSALGGKMLESGLGADGAISAMIREALL
HHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHH
RTSGNVSETARLTGMTRSQINYWIRRNRKVDVEF
HCCCCHHHHHHHHCCHHHHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3169574; 2993247; 2430049 [H]