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The map label for this gene is yciR [C]

Identifier: 87199442

GI number: 87199442

Start: 1462057

End: 1464231

Strand: Direct

Name: yciR [C]

Synonym: Saro_1421

Alternate gene names: 87199442

Gene position: 1462057-1464231 (Clockwise)

Preceding gene: 87199439

Following gene: 87199443

Centisome position: 41.05

GC content: 65.7

Gene sequence:

>2175_bases
ATGGTTGTCAGGGGATTGTTCAGGAGCCTTGGGCGCGGCGGAGCCGCAGACGCGGACGGCGGCGAATGTGCCGTCGCAGC
CGATGCGGGTGCGCCCGAGGAATCTTCTGCGCAGGTTGATCCTGCATCTCGGCTAGCCGTTCTCGACGCGTTCGAGCAGG
CTGGGTTCGGCTGGCTTTGGGCGACCGACGCCGAAGGGCGCCTGACCTACGTTTCCCTGTCCGCTCATACCAAGGCAGCC
GGCATGATCGGGCGGCCAATCGCGACCCTGATAGAAACAGACCGCGACGGCCCCGGCGAAAGCGCCGGCAGGCCGTTGAG
CTTCCAGCTGTCGAAGCGGGGACGCATAAACGATCTTGTCGTCCGATTTTCCGGGGACGAGCGCGACGGCAGGTGGTGGT
CTCTTTCCGGGCAGCCCAGCGTTTCGCCGGATGGCAGCTTTGCCGGCTATCGCGGTTTCGCGCGTGACGTGACGCAGGAA
TACACCCGCAAGCGCGAGGATTCGCGGGCGGCAGAATTCGATTCGCTTACCGGGCTCTACAACCGGCACAGGATGACGCG
CAGGCTGGATGCGATCCTGGCCGCGTTCCGCCAGGCCAACAGGTGCTGCGGCCTGATGATGCTCGATCTGGACAAGTTCA
AGCACGTCAACGACACGATGGGCCATCCTGCCGGTGACGAACTGCTTCGGCAGGTCGCCGAGCGCCTGCGCAAGGTCGTG
GGCGAGCGGGGCGAGATCGGCCGGCTGGGCGGCGACGAGTTCCAGATCATCCTGCCTGACATCGACGACCGGGGCCGACT
TGGCGAACTCGCCGCCAAGGTCATCCAGATTGTGTCGCAGCCATACGCCATCGAAGGCAAGCGTGCGGTGATCGGCACTT
CCGTCGGCATCGCGGTGGCGCCGCATGACGGGGAGGACCGCGAGGGTCTCGTTTCTTCCGCCGACCTTGCGCTTTATGCC
GCGAAGCACGGCGGACGCGGGCAGTTCCGTTTCTTCTCGACCGAGTTGAAGGACGAGGCCCAGGAGCGCACGATCCTCAA
TCAGGACCTGCGCGAGGCGTTGGCCCGCGACGAACTGGAACTGCACTACCAGCCGGTGGTGCGGATCGAGGACAACATCG
TCGTCGGCTTCGAGGCGCTGATGCGCTGGAACCATACGGAGCGCGGGCCAATCCCGCCCTCGCTGTTCATTCCGATCGCC
GAGGAGAGCAATCTCATCGTGCCATTGGGCGAATGGGCCCTGCGCAAGGCCTGCGAGGATGCTGCCGCCTGGCCCGACAG
CGTGCGGGTGGCGGTCAACGTCTCGCCCGTCCAGTTCGGCGTTGCGGGCTTCGTGACCTCGGTTGCAACTGCCGTGGCAC
AGAGCGGGATCGACCCCGAAAGGCTGGAGCTTGAGCTGACCGAGACGGTGTTCATGCGCGACAGCGAAGCGGTCGAAGAA
ACGTTCTCTGCGCTCAAGGCGCTTGGCGTGCGATTGGCGCTCGACGATTTCGGGACCGGGTATTCCTCGCTCAGTTATTT
GCGCTCGGCGCCCTTCGACAAGCTCAAGGTCGATCGCAGCTTTGTCGAGACGTGTGCCGCCAAGGACCAGAACAGCGCGA
AGATCATATCGGCCGTCCTCGGGCTGGCCGACGCGCTGGGCATGGAGACGACCGTGGAAGGCGTCGAGGCATTCGACCAG
CTCGAAGTGGTGCGAGAGCGTGGAGCCAAGCTGGTGCAGGGACATATCTTTGCCCATGCGATGCCCCATGCCGAAGTGGC
CGAGCGGCTTGCGGACAGCAATTTGCGCATCGAGCCCAACGGCCCCATGCGGCATCGGCCCGAGCGACGCGCGGTGTTCC
GCCGCGTGGTGGTGGTCCACGAGGATCATCGCTACGAGGCTGTCATGCGCGACCTTTCCCGGACGGGCGCACGGATCGAC
GGCTTGCTGGGGGTGCCGGTGGGCACGAGCCTGGTGATCGACCTCGGCGGAGGGCAACTGGTCGTGTCTATGGTCGTGCG
GTCGGACGAGGCCGTTATCGGCGTCGAGTTCGAGACTCCCCTGACCAGCGACGGAGCGGGTGGCTTGTGCACCCGCCACC
GCGTGCCGCCGTCGACACTGGCTGCCGCGACGGCGACCGCGGCGCCGCAAAGCAAGCCGCGCTTCATCCAGGTTGCGGTT
CCCGGGTCGCGTTGA

Upstream 100 bases:

>100_bases
ATCGCCGTGCAGGATGGGATCGCGTTAGGCCAGAAGTAACCAGAAGCTTTTATGACCTCATCGGGCTTTTACGGGAGAAG
TTCGGCAGGGCCGGCGGTAG

Downstream 100 bases:

>100_bases
AGGTTGCGATCGGCGGCGGACCCTTGCGCTCTTCCGCGCGTTCCCGCACATCGGCACCCGTCACGCAGTCAGCCGAGGAT
CAGTTTCACCCATGCCTTCC

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 724; Mature: 724

Protein sequence:

>724_residues
MVVRGLFRSLGRGGAADADGGECAVAADAGAPEESSAQVDPASRLAVLDAFEQAGFGWLWATDAEGRLTYVSLSAHTKAA
GMIGRPIATLIETDRDGPGESAGRPLSFQLSKRGRINDLVVRFSGDERDGRWWSLSGQPSVSPDGSFAGYRGFARDVTQE
YTRKREDSRAAEFDSLTGLYNRHRMTRRLDAILAAFRQANRCCGLMMLDLDKFKHVNDTMGHPAGDELLRQVAERLRKVV
GERGEIGRLGGDEFQIILPDIDDRGRLGELAAKVIQIVSQPYAIEGKRAVIGTSVGIAVAPHDGEDREGLVSSADLALYA
AKHGGRGQFRFFSTELKDEAQERTILNQDLREALARDELELHYQPVVRIEDNIVVGFEALMRWNHTERGPIPPSLFIPIA
EESNLIVPLGEWALRKACEDAAAWPDSVRVAVNVSPVQFGVAGFVTSVATAVAQSGIDPERLELELTETVFMRDSEAVEE
TFSALKALGVRLALDDFGTGYSSLSYLRSAPFDKLKVDRSFVETCAAKDQNSAKIISAVLGLADALGMETTVEGVEAFDQ
LEVVRERGAKLVQGHIFAHAMPHAEVAERLADSNLRIEPNGPMRHRPERRAVFRRVVVVHEDHRYEAVMRDLSRTGARID
GLLGVPVGTSLVIDLGGGQLVVSMVVRSDEAVIGVEFETPLTSDGAGGLCTRHRVPPSTLAAATATAAPQSKPRFIQVAV
PGSR

Sequences:

>Translated_724_residues
MVVRGLFRSLGRGGAADADGGECAVAADAGAPEESSAQVDPASRLAVLDAFEQAGFGWLWATDAEGRLTYVSLSAHTKAA
GMIGRPIATLIETDRDGPGESAGRPLSFQLSKRGRINDLVVRFSGDERDGRWWSLSGQPSVSPDGSFAGYRGFARDVTQE
YTRKREDSRAAEFDSLTGLYNRHRMTRRLDAILAAFRQANRCCGLMMLDLDKFKHVNDTMGHPAGDELLRQVAERLRKVV
GERGEIGRLGGDEFQIILPDIDDRGRLGELAAKVIQIVSQPYAIEGKRAVIGTSVGIAVAPHDGEDREGLVSSADLALYA
AKHGGRGQFRFFSTELKDEAQERTILNQDLREALARDELELHYQPVVRIEDNIVVGFEALMRWNHTERGPIPPSLFIPIA
EESNLIVPLGEWALRKACEDAAAWPDSVRVAVNVSPVQFGVAGFVTSVATAVAQSGIDPERLELELTETVFMRDSEAVEE
TFSALKALGVRLALDDFGTGYSSLSYLRSAPFDKLKVDRSFVETCAAKDQNSAKIISAVLGLADALGMETTVEGVEAFDQ
LEVVRERGAKLVQGHIFAHAMPHAEVAERLADSNLRIEPNGPMRHRPERRAVFRRVVVVHEDHRYEAVMRDLSRTGARID
GLLGVPVGTSLVIDLGGGQLVVSMVVRSDEAVIGVEFETPLTSDGAGGLCTRHRVPPSTLAAATATAAPQSKPRFIQVAV
PGSR
>Mature_724_residues
MVVRGLFRSLGRGGAADADGGECAVAADAGAPEESSAQVDPASRLAVLDAFEQAGFGWLWATDAEGRLTYVSLSAHTKAA
GMIGRPIATLIETDRDGPGESAGRPLSFQLSKRGRINDLVVRFSGDERDGRWWSLSGQPSVSPDGSFAGYRGFARDVTQE
YTRKREDSRAAEFDSLTGLYNRHRMTRRLDAILAAFRQANRCCGLMMLDLDKFKHVNDTMGHPAGDELLRQVAERLRKVV
GERGEIGRLGGDEFQIILPDIDDRGRLGELAAKVIQIVSQPYAIEGKRAVIGTSVGIAVAPHDGEDREGLVSSADLALYA
AKHGGRGQFRFFSTELKDEAQERTILNQDLREALARDELELHYQPVVRIEDNIVVGFEALMRWNHTERGPIPPSLFIPIA
EESNLIVPLGEWALRKACEDAAAWPDSVRVAVNVSPVQFGVAGFVTSVATAVAQSGIDPERLELELTETVFMRDSEAVEE
TFSALKALGVRLALDDFGTGYSSLSYLRSAPFDKLKVDRSFVETCAAKDQNSAKIISAVLGLADALGMETTVEGVEAFDQ
LEVVRERGAKLVQGHIFAHAMPHAEVAERLADSNLRIEPNGPMRHRPERRAVFRRVVVVHEDHRYEAVMRDLSRTGARID
GLLGVPVGTSLVIDLGGGQLVVSMVVRSDEAVIGVEFETPLTSDGAGGLCTRHRVPPSTLAAATATAAPQSKPRFIQVAV
PGSR

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=431, Percent_Identity=36.8909512761021, Blast_Score=260, Evalue=3e-70,
Organism=Escherichia coli, GI87081921, Length=438, Percent_Identity=30.8219178082192, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI226510982, Length=425, Percent_Identity=27.0588235294118, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1790496, Length=236, Percent_Identity=33.0508474576271, Blast_Score=142, Evalue=1e-34,
Organism=Escherichia coli, GI1786507, Length=251, Percent_Identity=31.8725099601594, Blast_Score=139, Evalue=7e-34,
Organism=Escherichia coli, GI1788502, Length=239, Percent_Identity=33.8912133891213, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI87081980, Length=271, Percent_Identity=32.8413284132841, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI1788381, Length=510, Percent_Identity=26.078431372549, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI87081743, Length=250, Percent_Identity=30.8, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1787055, Length=290, Percent_Identity=30.3448275862069, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI87081845, Length=243, Percent_Identity=33.3333333333333, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788849, Length=268, Percent_Identity=28.3582089552239, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788956, Length=156, Percent_Identity=33.974358974359, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787802, Length=164, Percent_Identity=31.0975609756098, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI87082096, Length=395, Percent_Identity=21.0126582278481, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1787262, Length=174, Percent_Identity=31.6091954022989, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786584, Length=172, Percent_Identity=32.5581395348837, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081977, Length=159, Percent_Identity=33.9622641509434, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI145693134, Length=168, Percent_Identity=34.5238095238095, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081881, Length=254, Percent_Identity=26.7716535433071, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082007, Length=184, Percent_Identity=29.8913043478261, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787056, Length=128, Percent_Identity=38.28125, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081974, Length=93, Percent_Identity=38.7096774193548, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787816, Length=168, Percent_Identity=32.1428571428571, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 78534; Mature: 78534

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVRGLFRSLGRGGAADADGGECAVAADAGAPEESSAQVDPASRLAVLDAFEQAGFGWLW
CCCHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEE
ATDAEGRLTYVSLSAHTKAAGMIGRPIATLIETDRDGPGESAGRPLSFQLSKRGRINDLV
EECCCCEEEEEEEECCCHHHCCCCCHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCEEEE
VRFSGDERDGRWWSLSGQPSVSPDGSFAGYRGFARDVTQEYTRKREDSRAAEFDSLTGLY
EEECCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRHRMTRRLDAILAAFRQANRCCGLMMLDLDKFKHVNDTMGHPAGDELLRQVAERLRKVV
HHHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHH
GERGEIGRLGGDEFQIILPDIDDRGRLGELAAKVIQIVSQPYAIEGKRAVIGTSVGIAVA
CCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEECCCEEEEEECCEEEEC
PHDGEDREGLVSSADLALYAAKHGGRGQFRFFSTELKDEAQERTILNQDLREALARDELE
CCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCHH
LHYQPVVRIEDNIVVGFEALMRWNHTERGPIPPSLFIPIAEESNLIVPLGEWALRKACED
EEECCEEEEECCEEEEHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEECCHHHHHHHHHH
AAAWPDSVRVAVNVSPVQFGVAGFVTSVATAVAQSGIDPERLELELTETVFMRDSEAVEE
HHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEEHHHHHCCHHHHHH
TFSALKALGVRLALDDFGTGYSSLSYLRSAPFDKLKVDRSFVETCAAKDQNSAKIISAVL
HHHHHHHHCCEEEEHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GLADALGMETTVEGVEAFDQLEVVRERGAKLVQGHIFAHAMPHAEVAERLADSNLRIEPN
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCCCEECCC
GPMRHRPERRAVFRRVVVVHEDHRYEAVMRDLSRTGARIDGLLGVPVGTSLVIDLGGGQL
CCCCCCCHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCCCCEEECCCCCEEEEECCCCCE
VVSMVVRSDEAVIGVEFETPLTSDGAGGLCTRHRVPPSTLAAATATAAPQSKPRFIQVAV
EHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEC
PGSR
CCCC
>Mature Secondary Structure
MVVRGLFRSLGRGGAADADGGECAVAADAGAPEESSAQVDPASRLAVLDAFEQAGFGWLW
CCCHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEE
ATDAEGRLTYVSLSAHTKAAGMIGRPIATLIETDRDGPGESAGRPLSFQLSKRGRINDLV
EECCCCEEEEEEEECCCHHHCCCCCHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCEEEE
VRFSGDERDGRWWSLSGQPSVSPDGSFAGYRGFARDVTQEYTRKREDSRAAEFDSLTGLY
EEECCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRHRMTRRLDAILAAFRQANRCCGLMMLDLDKFKHVNDTMGHPAGDELLRQVAERLRKVV
HHHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHH
GERGEIGRLGGDEFQIILPDIDDRGRLGELAAKVIQIVSQPYAIEGKRAVIGTSVGIAVA
CCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEECCCEEEEEECCEEEEC
PHDGEDREGLVSSADLALYAAKHGGRGQFRFFSTELKDEAQERTILNQDLREALARDELE
CCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCHH
LHYQPVVRIEDNIVVGFEALMRWNHTERGPIPPSLFIPIAEESNLIVPLGEWALRKACED
EEECCEEEEECCEEEEHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEECCHHHHHHHHHH
AAAWPDSVRVAVNVSPVQFGVAGFVTSVATAVAQSGIDPERLELELTETVFMRDSEAVEE
HHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEEHHHHHCCHHHHHH
TFSALKALGVRLALDDFGTGYSSLSYLRSAPFDKLKVDRSFVETCAAKDQNSAKIISAVL
HHHHHHHHCCEEEEHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GLADALGMETTVEGVEAFDQLEVVRERGAKLVQGHIFAHAMPHAEVAERLADSNLRIEPN
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCCCEECCC
GPMRHRPERRAVFRRVVVVHEDHRYEAVMRDLSRTGARIDGLLGVPVGTSLVIDLGGGQL
CCCCCCCHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCCCCEEECCCCCEEEEECCCCCE
VVSMVVRSDEAVIGVEFETPLTSDGAGGLCTRHRVPPSTLAAATATAAPQSKPRFIQVAV
EHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEC
PGSR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]