| Definition | Novosphingobium aromaticivorans DSM 12444 chromosome, complete genome. |
|---|---|
| Accession | NC_007794 |
| Length | 3,561,584 |
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The map label for this gene is crt [H]
Identifier: 87199438
GI number: 87199438
Start: 1459207
End: 1459983
Strand: Direct
Name: crt [H]
Synonym: Saro_1417
Alternate gene names: 87199438
Gene position: 1459207-1459983 (Clockwise)
Preceding gene: 87199433
Following gene: 87199439
Centisome position: 40.97
GC content: 68.21
Gene sequence:
>777_bases ATGCTTGTGAACCTCGATCGCCACGGCGCCGTTGCCGTGGTCACGCTCAACCGGCCCGAGGCGATGAACGCGCTGTCCGC CGCGCTGCGGGTGGAACTGGCCCGTACGATGTGCGAAGTCGATGCTGACGACGGGGTGCGGGCAGTGGTTCTGACCGGCG CGGGCCAGCGCGCGTTCACCGCCGGGCTCGATCTCAAGGAATTGGGGGCGGATACGTCCAACCTCGGGGCGGCCAATGCG CAGGACGCAGATCGCAATCCGGTGAAGGCGGTGGAGCAGTGCCGCAAGCCGGTGATCGGCGCGATCAACGGCGTCGCAGT CACCGGCGGGTTCGAACTGGCGCTGGCCTGCGATGTGCTGATCGCCAGCGAGAATGCCCGCTTTGCCGACACCCACGCGC GGGTCGGCATCATGCCCGGCTGGGGCCTGTCGCAGAAGCTTTCGCGGATGATCGGCATCTCGCGGGCCAAGGAACTGTCG CTGACGGGAAATTTCATCGGTGCGGAGCAGGCGCATGCCTGGGGGCTCGTCAACCGCGTCGTGCCGGCGGACGAGTTGCT GCCTGCCGCCATCGCCCTGGCGCAAGACATGGCGACGATCGAACCGGACATGGCGAGCACCTACAAGCGGCTGATCGACG AAGGATATGCGCTGCCCATGGGCGAGGCGCTGGCGCTGGAGACGCGCGTTTCGGCCGAACGGAATGGCACGGTGCGGGCC GACGAGGTCGAGGCAAGGCGCCGGGCGGTGATGGATCGCGGTCGCGGGCAGGCGTGA
Upstream 100 bases:
>100_bases CTTAGCGATTCCCGCGTGGAAAGCAAGCGCGAACTTGGCGCTGCGACCCTTGCCAAGCCCGGAGCGCTTGGGTTTAATCG CGCCCTTAAGGGAGAACGCG
Downstream 100 bases:
>100_bases CGGATAGGGGAGGGGAACGGCGATGACTGCAATGGGGCGGCGGCTGGTGCTGCTTGGTGCTGGACTGGTGATGGCAGGAA TGCTGACCGGGTTCGTGTCC
Product: enoyl-CoA hydratase
Products: NA
Alternate protein names: Crotonase [H]
Number of amino acids: Translated: 258; Mature: 258
Protein sequence:
>258_residues MLVNLDRHGAVAVVTLNRPEAMNALSAALRVELARTMCEVDADDGVRAVVLTGAGQRAFTAGLDLKELGADTSNLGAANA QDADRNPVKAVEQCRKPVIGAINGVAVTGGFELALACDVLIASENARFADTHARVGIMPGWGLSQKLSRMIGISRAKELS LTGNFIGAEQAHAWGLVNRVVPADELLPAAIALAQDMATIEPDMASTYKRLIDEGYALPMGEALALETRVSAERNGTVRA DEVEARRRAVMDRGRGQA
Sequences:
>Translated_258_residues MLVNLDRHGAVAVVTLNRPEAMNALSAALRVELARTMCEVDADDGVRAVVLTGAGQRAFTAGLDLKELGADTSNLGAANA QDADRNPVKAVEQCRKPVIGAINGVAVTGGFELALACDVLIASENARFADTHARVGIMPGWGLSQKLSRMIGISRAKELS LTGNFIGAEQAHAWGLVNRVVPADELLPAAIALAQDMATIEPDMASTYKRLIDEGYALPMGEALALETRVSAERNGTVRA DEVEARRRAVMDRGRGQA >Mature_258_residues MLVNLDRHGAVAVVTLNRPEAMNALSAALRVELARTMCEVDADDGVRAVVLTGAGQRAFTAGLDLKELGADTSNLGAANA QDADRNPVKAVEQCRKPVIGAINGVAVTGGFELALACDVLIASENARFADTHARVGIMPGWGLSQKLSRMIGISRAKELS LTGNFIGAEQAHAWGLVNRVVPADELLPAAIALAQDMATIEPDMASTYKRLIDEGYALPMGEALALETRVSAERNGTVRA DEVEARRRAVMDRGRGQA
Specific function: Catalyzes The Reversible Dehydration Of L-Carnitinyl-CoA To Crotobetainyl-CoA. [C]
COG id: COG1024
COG function: function code I; Enoyl-CoA hydratase/carnithine racemase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]
Homologues:
Organism=Homo sapiens, GI194097323, Length=225, Percent_Identity=35.5555555555556, Blast_Score=135, Evalue=2e-32, Organism=Homo sapiens, GI20127408, Length=183, Percent_Identity=34.9726775956284, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI70995211, Length=188, Percent_Identity=32.4468085106383, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI68989263, Length=192, Percent_Identity=31.25, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI31542718, Length=219, Percent_Identity=27.3972602739726, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI4502327, Length=227, Percent_Identity=30.3964757709251, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI116235487, Length=180, Percent_Identity=29.4444444444444, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI62530384, Length=209, Percent_Identity=32.0574162679426, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI37594469, Length=195, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI37594471, Length=195, Percent_Identity=26.6666666666667, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI25453481, Length=226, Percent_Identity=26.1061946902655, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI51538573, Length=226, Percent_Identity=26.1061946902655, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI4757966, Length=226, Percent_Identity=26.1061946902655, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI51538581, Length=226, Percent_Identity=26.1061946902655, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI4757968, Length=177, Percent_Identity=28.8135593220339, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI49355787, Length=177, Percent_Identity=28.8135593220339, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI295842266, Length=207, Percent_Identity=31.8840579710145, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI221142681, Length=226, Percent_Identity=35.8407079646018, Blast_Score=131, Evalue=5e-32, Organism=Escherichia coli, GI1787659, Length=231, Percent_Identity=37.6623376623377, Blast_Score=125, Evalue=2e-30, Organism=Escherichia coli, GI1787660, Length=228, Percent_Identity=36.8421052631579, Blast_Score=105, Evalue=2e-24, Organism=Escherichia coli, GI1788597, Length=198, Percent_Identity=32.8282828282828, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI1788682, Length=188, Percent_Identity=32.9787234042553, Blast_Score=91, Evalue=7e-20, Organism=Escherichia coli, GI87082183, Length=254, Percent_Identity=26.7716535433071, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1790281, Length=191, Percent_Identity=29.3193717277487, Blast_Score=72, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17554946, Length=220, Percent_Identity=39.5454545454545, Blast_Score=157, Evalue=6e-39, Organism=Caenorhabditis elegans, GI25145438, Length=233, Percent_Identity=36.9098712446352, Blast_Score=149, Evalue=2e-36, Organism=Caenorhabditis elegans, GI17540714, Length=223, Percent_Identity=30.9417040358744, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17560910, Length=215, Percent_Identity=31.1627906976744, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17558304, Length=180, Percent_Identity=31.1111111111111, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI25144276, Length=191, Percent_Identity=30.3664921465969, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17508951, Length=191, Percent_Identity=30.3664921465969, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17508953, Length=191, Percent_Identity=30.3664921465969, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17534483, Length=207, Percent_Identity=28.5024154589372, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17536985, Length=211, Percent_Identity=27.0142180094787, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17535521, Length=220, Percent_Identity=28.6363636363636, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17549921, Length=182, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17540306, Length=181, Percent_Identity=28.1767955801105, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI25144160, Length=190, Percent_Identity=30.5263157894737, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI25144157, Length=190, Percent_Identity=30.5263157894737, Blast_Score=70, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6320241, Length=183, Percent_Identity=25.6830601092896, Blast_Score=69, Evalue=6e-13, Organism=Drosophila melanogaster, GI20129971, Length=220, Percent_Identity=38.6363636363636, Blast_Score=158, Evalue=4e-39, Organism=Drosophila melanogaster, GI24653477, Length=220, Percent_Identity=38.6363636363636, Blast_Score=158, Evalue=4e-39, Organism=Drosophila melanogaster, GI24653139, Length=225, Percent_Identity=32.8888888888889, Blast_Score=108, Evalue=5e-24, Organism=Drosophila melanogaster, GI21357171, Length=213, Percent_Identity=32.3943661971831, Blast_Score=100, Evalue=8e-22, Organism=Drosophila melanogaster, GI19920382, Length=213, Percent_Identity=31.4553990610329, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24654903, Length=214, Percent_Identity=28.5046728971963, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI19922422, Length=188, Percent_Identity=29.7872340425532, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI24650670, Length=203, Percent_Identity=33.0049261083744, Blast_Score=88, Evalue=7e-18,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014748 - InterPro: IPR001753 - InterPro: IPR018376 [H]
Pfam domain/function: PF00378 ECH [H]
EC number: =4.2.1.55 [H]
Molecular weight: Translated: 27239; Mature: 27239
Theoretical pI: Translated: 5.18; Mature: 5.18
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 3.5 %Met (Translated Protein) 4.7 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 3.5 %Met (Mature Protein) 4.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLVNLDRHGAVAVVTLNRPEAMNALSAALRVELARTMCEVDADDGVRAVVLTGAGQRAFT CEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEE AGLDLKELGADTSNLGAANAQDADRNPVKAVEQCRKPVIGAINGVAVTGGFELALACDVL CCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCEEEEEEEEEE IASENARFADTHARVGIMPGWGLSQKLSRMIGISRAKELSLTGNFIGAEQAHAWGLVNRV EECCCCCEECCCCEEECCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHC VPADELLPAAIALAQDMATIEPDMASTYKRLIDEGYALPMGEALALETRVSAERNGTVRA CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCEEHHHHHCCCCCCCCCH DEVEARRRAVMDRGRGQA HHHHHHHHHHHHCCCCCC >Mature Secondary Structure MLVNLDRHGAVAVVTLNRPEAMNALSAALRVELARTMCEVDADDGVRAVVLTGAGQRAFT CEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEE AGLDLKELGADTSNLGAANAQDADRNPVKAVEQCRKPVIGAINGVAVTGGFELALACDVL CCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCEEEEEEEEEE IASENARFADTHARVGIMPGWGLSQKLSRMIGISRAKELSLTGNFIGAEQAHAWGLVNRV EECCCCCEECCCCEEECCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHC VPADELLPAAIALAQDMATIEPDMASTYKRLIDEGYALPMGEALALETRVSAERNGTVRA CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCEEHHHHHCCCCCCCCCH DEVEARRRAVMDRGRGQA HHHHHHHHHHHHCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8655474; 11466286 [H]