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The map label for this gene is yleA [C]

Identifier: 87199422

GI number: 87199422

Start: 1443487

End: 1444683

Strand: Reverse

Name: yleA [C]

Synonym: Saro_1401

Alternate gene names: 87199422

Gene position: 1444683-1443487 (Counterclockwise)

Preceding gene: 87199423

Following gene: 87199421

Centisome position: 40.56

GC content: 65.58

Gene sequence:

>1197_bases
ATGAGCGTCGAGGTCATATCCCTCGGCTGCCGCCTCAACATCGCCGAAAGCGAGGCGATACGGGGACTTATCGCGGACGG
GCCGCCCACCGTCGTCGTCAATTCCTGCGCCGTCACGGCAGAGGCGGTGCGCCAGTCGCGCCGCGCGGTACGCCGTCTCC
GCCGCGAAAATCCGGAGGCCCGCCTCGTCGTGACCGGCTGCGCGGCGACGATCGAGCGCGACGCATTCGCCGGAATGGTC
GAGGTCGATGCGGTGGTGCCCAACGCGGCCAAGCTGGAACCGTCCAGTTGGAATGCTCCAACCGGCGCGCGCCCCCTGCC
CCGGCGGGCGCATACCCGCGCTTTCATTCCTGTCCAGAATGGCTGCGATCATAGTTGCACCTTCTGCATCATCCCCCAAG
GGCGCGGAAAAAGCGTTTCCCTTCCAGTGGTTGATGTGATTTCAGCGGTCGAAAGGGCGATTTTTGCGCTGCGACCCGAA
CGGCACCTAACCGTACACGAGGTGGTCCTGACCGGCGTCGACGTGACCTCGTGGGGCGCCGACCTGCCATCAGGACCGGC
CTTGGGAAACCTGATCGCGGCGATCCTCGATGCATTTCCGGAATTGCCGCGCCTGCGGCTCTCCTCGCTCGACGGCGTGG
AGATCGACCCCCTCCTTTTCGACCTCATAACCGGCGAGCCGCGCGTCATGCCGCACGTCCATCTCTCGCTCCAGTCGGGC
GATGACATGGTGCTCAAGCGGATGAAGCGGCGCCACAGCAGGCGCGATGCCATCGAACTCGTCCAGCGCATGAAAGCACG
CCGTCCGGACATTGCCGTGGGTGCCGACCTGATCGCCGGCTTTCCGACAGAAACCCCTGAAATGCATCGGAACAATCTTT
CGATCGTGCGGGAATGCGGCATCGTCCACGGCCACGTCTTCCCCTACTCTCCCCGCCCCGGCACCCCCGCCGCGCTGATG
CCCCAGGTCGAACCGGCAGTGGTTCGGGAGCGTGCGGCGGAATTGCGGGCAGCGGTGGCCACGGAACGCGCCCGCTGGCT
CGCCTCGCTCGTCGGCAAACCAGCGCAGGTGCTTGCCGAGCGCGACGGAACCGGCCATGCGGGCCACTTTGCGACCTATC
GCGTAACGGACGGCGTGACTGCGGGCAGCCTCGTCATGGTGACGCCGACCAAGATTGTTGAAGGAATACTGGAATGA

Upstream 100 bases:

>100_bases
GCCCGCTCACCATCACCTGGCCTGAAGGCGGGACCATCGATATGACCGGGCCTGCGACGCTGAGCTTCGAAGGCGCGTTC
GAGGACTCAGACTTCCCGGC

Downstream 100 bases:

>100_bases
GTGGCGAAAGCTGGTCCGATAGAATCCTCGGGGGCTTCCGCAAGACGTCAGAGCGGCTCGCCGAAAACCTTGGCGGCATC
GTCGGCAGCAGCCGACTGAC

Product: MiaB-like tRNA modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSVEVISLGCRLNIAESEAIRGLIADGPPTVVVNSCAVTAEAVRQSRRAVRRLRRENPEARLVVTGCAATIERDAFAGMV
EVDAVVPNAAKLEPSSWNAPTGARPLPRRAHTRAFIPVQNGCDHSCTFCIIPQGRGKSVSLPVVDVISAVERAIFALRPE
RHLTVHEVVLTGVDVTSWGADLPSGPALGNLIAAILDAFPELPRLRLSSLDGVEIDPLLFDLITGEPRVMPHVHLSLQSG
DDMVLKRMKRRHSRRDAIELVQRMKARRPDIAVGADLIAGFPTETPEMHRNNLSIVRECGIVHGHVFPYSPRPGTPAALM
PQVEPAVVRERAAELRAAVATERARWLASLVGKPAQVLAERDGTGHAGHFATYRVTDGVTAGSLVMVTPTKIVEGILE

Sequences:

>Translated_398_residues
MSVEVISLGCRLNIAESEAIRGLIADGPPTVVVNSCAVTAEAVRQSRRAVRRLRRENPEARLVVTGCAATIERDAFAGMV
EVDAVVPNAAKLEPSSWNAPTGARPLPRRAHTRAFIPVQNGCDHSCTFCIIPQGRGKSVSLPVVDVISAVERAIFALRPE
RHLTVHEVVLTGVDVTSWGADLPSGPALGNLIAAILDAFPELPRLRLSSLDGVEIDPLLFDLITGEPRVMPHVHLSLQSG
DDMVLKRMKRRHSRRDAIELVQRMKARRPDIAVGADLIAGFPTETPEMHRNNLSIVRECGIVHGHVFPYSPRPGTPAALM
PQVEPAVVRERAAELRAAVATERARWLASLVGKPAQVLAERDGTGHAGHFATYRVTDGVTAGSLVMVTPTKIVEGILE
>Mature_397_residues
SVEVISLGCRLNIAESEAIRGLIADGPPTVVVNSCAVTAEAVRQSRRAVRRLRRENPEARLVVTGCAATIERDAFAGMVE
VDAVVPNAAKLEPSSWNAPTGARPLPRRAHTRAFIPVQNGCDHSCTFCIIPQGRGKSVSLPVVDVISAVERAIFALRPER
HLTVHEVVLTGVDVTSWGADLPSGPALGNLIAAILDAFPELPRLRLSSLDGVEIDPLLFDLITGEPRVMPHVHLSLQSGD
DMVLKRMKRRHSRRDAIELVQRMKARRPDIAVGADLIAGFPTETPEMHRNNLSIVRECGIVHGHVFPYSPRPGTPAALMP
QVEPAVVRERAAELRAAVATERARWLASLVGKPAQVLAERDGTGHAGHFATYRVTDGVTAGSLVMVTPTKIVEGILE

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=362, Percent_Identity=26.7955801104972, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI28872784, Length=274, Percent_Identity=29.5620437956204, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI28872782, Length=274, Percent_Identity=29.5620437956204, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1786882, Length=398, Percent_Identity=24.8743718592965, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1787057, Length=400, Percent_Identity=26.75, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17553146, Length=440, Percent_Identity=25.4545454545455, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71996771, Length=287, Percent_Identity=29.9651567944251, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21356207, Length=372, Percent_Identity=25.5376344086022, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI19922432, Length=409, Percent_Identity=25.6723716381418, Blast_Score=109, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 42962; Mature: 42831

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVEVISLGCRLNIAESEAIRGLIADGPPTVVVNSCAVTAEAVRQSRRAVRRLRRENPEA
CCEEEEEECCEEEECHHHHHHEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCE
RLVVTGCAATIERDAFAGMVEVDAVVPNAAKLEPSSWNAPTGARPLPRRAHTRAFIPVQN
EEEEEECHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCC
GCDHSCTFCIIPQGRGKSVSLPVVDVISAVERAIFALRPERHLTVHEVVLTGVDVTSWGA
CCCCCCEEEEEECCCCCEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCC
DLPSGPALGNLIAAILDAFPELPRLRLSSLDGVEIDPLLFDLITGEPRVMPHVHLSLQSG
CCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCEECHHHHHHHCCCCCCCCEEEEEECCC
DDMVLKRMKRRHSRRDAIELVQRMKARRPDIAVGADLIAGFPTETPEMHRNNLSIVRECG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHCCCCCCCHHHHCCCHHHHHHCC
IVHGHVFPYSPRPGTPAALMPQVEPAVVRERAAELRAAVATERARWLASLVGKPAQVLAE
CEECCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RDGTGHAGHFATYRVTDGVTAGSLVMVTPTKIVEGILE
CCCCCCCCCEEEEEEECCCCCCCEEEECHHHHHHHHCC
>Mature Secondary Structure 
SVEVISLGCRLNIAESEAIRGLIADGPPTVVVNSCAVTAEAVRQSRRAVRRLRRENPEA
CEEEEEECCEEEECHHHHHHEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCE
RLVVTGCAATIERDAFAGMVEVDAVVPNAAKLEPSSWNAPTGARPLPRRAHTRAFIPVQN
EEEEEECHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCC
GCDHSCTFCIIPQGRGKSVSLPVVDVISAVERAIFALRPERHLTVHEVVLTGVDVTSWGA
CCCCCCEEEEEECCCCCEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCC
DLPSGPALGNLIAAILDAFPELPRLRLSSLDGVEIDPLLFDLITGEPRVMPHVHLSLQSG
CCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCEECHHHHHHHCCCCCCCCEEEEEECCC
DDMVLKRMKRRHSRRDAIELVQRMKARRPDIAVGADLIAGFPTETPEMHRNNLSIVRECG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHCCCCCCCHHHHCCCHHHHHHCC
IVHGHVFPYSPRPGTPAALMPQVEPAVVRERAAELRAAVATERARWLASLVGKPAQVLAE
CEECCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RDGTGHAGHFATYRVTDGVTAGSLVMVTPTKIVEGILE
CCCCCCCCCEEEEEEECCCCCCCEEEECHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]