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The map label for this gene is frr

Identifier: 87199393

GI number: 87199393

Start: 1419217

End: 1419774

Strand: Direct

Name: frr

Synonym: Saro_1372

Alternate gene names: 87199393

Gene position: 1419217-1419774 (Clockwise)

Preceding gene: 87199392

Following gene: 87199394

Centisome position: 39.85

GC content: 63.08

Gene sequence:

>558_bases
ATGGCCAAGTATGACAAGGCGGACCTCGAGCGCCGCATGAAGGGCGCCGTGGAATCGCTGAGGGGCGATCTTTCGGGCCT
GCGCACCGGCCGCGCCAACACTGCGCTGCTCGATCCGATCGTGGTCGAAGTCTACGGCAGCCACATGCCGCTGGCCCAGG
TGGCGACCGTCTCTGCTCCCGAGCCGCGTCTGCTTTCGGTGCAGGTGTGGGACAAGTCGAATGTGACCCCAGTTGAAAAG
GCGATCCGCTCTGCGGGCCTCGGGCTCAACCCGATCAGCGACGGCAATACGCTGCGCCTGCCTATCCCCGACCTTACCGA
AGAGCGCCGCAAGGAACTGGCCAAGCTTGCCAGCAAGTATGCCGAAAACGCCCGTATCGCGATCCGCAACGTGCGTCGTG
ATGGCATGGACGCGCTGAAGGCGGACGAGAGCAAGAAGGAAATCTCGGAAGACGAGCGCAAGCGCGCCGAGACCGATCTG
CAGAAGCTGACCGACGATATCATCAAGCAGGCGGACGAAGCTGCCGCGGCCAAGGAGAAGGAAATCCTCGGCAAGTGA

Upstream 100 bases:

>100_bases
AACATTCCCATCGTCGTCTTCTCGATCCGCGAACGGGGCAATCTGGCCCGCGTACTTGCGGGTGAGGGGACGCAGACCAC
CGTGAAGAAGGAAGCCTGAC

Downstream 100 bases:

>100_bases
CCGCAGTCCCCGCCTCGACCGGCGGCACCGCGCCGCATGGCGCGCGGCATGTTGCCATCATCATGGATGGCAATGGTCGC
TGGGCGAAGAAGCGCATGAT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MAKYDKADLERRMKGAVESLRGDLSGLRTGRANTALLDPIVVEVYGSHMPLAQVATVSAPEPRLLSVQVWDKSNVTPVEK
AIRSAGLGLNPISDGNTLRLPIPDLTEERRKELAKLASKYAENARIAIRNVRRDGMDALKADESKKEISEDERKRAETDL
QKLTDDIIKQADEAAAAKEKEILGK

Sequences:

>Translated_185_residues
MAKYDKADLERRMKGAVESLRGDLSGLRTGRANTALLDPIVVEVYGSHMPLAQVATVSAPEPRLLSVQVWDKSNVTPVEK
AIRSAGLGLNPISDGNTLRLPIPDLTEERRKELAKLASKYAENARIAIRNVRRDGMDALKADESKKEISEDERKRAETDL
QKLTDDIIKQADEAAAAKEKEILGK
>Mature_184_residues
AKYDKADLERRMKGAVESLRGDLSGLRTGRANTALLDPIVVEVYGSHMPLAQVATVSAPEPRLLSVQVWDKSNVTPVEKA
IRSAGLGLNPISDGNTLRLPIPDLTEERRKELAKLASKYAENARIAIRNVRRDGMDALKADESKKEISEDERKRAETDLQ
KLTDDIIKQADEAAAAKEKEILGK

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=178, Percent_Identity=32.5842696629214, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI291042689, Length=149, Percent_Identity=35.5704697986577, Blast_Score=89, Evalue=2e-18,
Organism=Escherichia coli, GI1786368, Length=178, Percent_Identity=50, Blast_Score=166, Evalue=6e-43,
Organism=Drosophila melanogaster, GI24661488, Length=177, Percent_Identity=31.0734463276836, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_NOVAD (Q2G8K7)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_496650.1
- ProteinModelPortal:   Q2G8K7
- SMR:   Q2G8K7
- STRING:   Q2G8K7
- GeneID:   3917826
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_1372
- NMPDR:   fig|48935.1.peg.1229
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   NARO279238:SARO_1372-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20386; Mature: 20255

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKYDKADLERRMKGAVESLRGDLSGLRTGRANTALLDPIVVEVYGSHMPLAQVATVSAP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCC
EPRLLSVQVWDKSNVTPVEKAIRSAGLGLNPISDGNTLRLPIPDLTEERRKELAKLASKY
CCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHH
AENARIAIRNVRRDGMDALKADESKKEISEDERKRAETDLQKLTDDIIKQADEAAAAKEK
HHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EILGK
HHCCC
>Mature Secondary Structure 
AKYDKADLERRMKGAVESLRGDLSGLRTGRANTALLDPIVVEVYGSHMPLAQVATVSAP
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCC
EPRLLSVQVWDKSNVTPVEKAIRSAGLGLNPISDGNTLRLPIPDLTEERRKELAKLASKY
CCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHH
AENARIAIRNVRRDGMDALKADESKKEISEDERKRAETDLQKLTDDIIKQADEAAAAKEK
HHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EILGK
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA