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The map label for this gene is lrp [H]

Identifier: 87199372

GI number: 87199372

Start: 1397513

End: 1397980

Strand: Direct

Name: lrp [H]

Synonym: Saro_1351

Alternate gene names: 87199372

Gene position: 1397513-1397980 (Clockwise)

Preceding gene: 87199368

Following gene: 87199374

Centisome position: 39.24

GC content: 61.97

Gene sequence:

>468_bases
ATGGCAACCTTGGACGGTATCGACCGGCGGCTTCTCGCCGAACTACAGGCAGAAGGGCGGGTAACCAACGTGGAACTCGC
ACAGCGCGTGGGGCTCACCGCGCCGCCGTGCCTGCGCCGTGTCCGCGCGCTCGAGGATGCGGGCGTCATCAAGGGCTACC
ATGCCGAACTCGATGCCTCGAAGCTCGGATTCGCGATCACTGTCTTCGCGCTTGTCAGCCTCAAGAGCCAGGCCGAGGAA
TCGCTCCGCCAGTTCGAGGATCACATGCGCACGCTGCCCGAAGTGCGAGAGTGTCACATGCTGAACGGCGAGATCGATTT
CATCCTCAAGATCGTCAGCAAGGACCTGCAAAGCTTCCAGGAATTCCTGACGAGCAAGCTTACGCCGGCCCCCAACGTGG
CAAGCGTGAAGACCTCGCTGACGATTCGCACGGCCAAGCAGGTGCCTGGGGTGCCTTTGGAAGACTGA

Upstream 100 bases:

>100_bases
TAAAATTATCGCCCGATCATCGATTTTGTGCGGAAAGTTGCCAGACATGCTTCTTTCTGAACGCTACGACGGGCGAAGGT
GAAACGGACGAATTGAAGGC

Downstream 100 bases:

>100_bases
CGGAAGTCCGAATGGACTTTCGCCTCTCCTGCCTCAGTCCGTCGAACTTGCCGCGCGTTCGTGGTGACGGATCACTTCCT
GGATGACGAAGCGCAGGAAC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MATLDGIDRRLLAELQAEGRVTNVELAQRVGLTAPPCLRRVRALEDAGVIKGYHAELDASKLGFAITVFALVSLKSQAEE
SLRQFEDHMRTLPEVRECHMLNGEIDFILKIVSKDLQSFQEFLTSKLTPAPNVASVKTSLTIRTAKQVPGVPLED

Sequences:

>Translated_155_residues
MATLDGIDRRLLAELQAEGRVTNVELAQRVGLTAPPCLRRVRALEDAGVIKGYHAELDASKLGFAITVFALVSLKSQAEE
SLRQFEDHMRTLPEVRECHMLNGEIDFILKIVSKDLQSFQEFLTSKLTPAPNVASVKTSLTIRTAKQVPGVPLED
>Mature_154_residues
ATLDGIDRRLLAELQAEGRVTNVELAQRVGLTAPPCLRRVRALEDAGVIKGYHAELDASKLGFAITVFALVSLKSQAEES
LRQFEDHMRTLPEVRECHMLNGEIDFILKIVSKDLQSFQEFLTSKLTPAPNVASVKTSLTIRTAKQVPGVPLED

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=144, Percent_Identity=39.5833333333333, Blast_Score=118, Evalue=2e-28,
Organism=Escherichia coli, GI87081742, Length=151, Percent_Identity=31.7880794701987, Blast_Score=96, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17112; Mature: 16981

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLDGIDRRLLAELQAEGRVTNVELAQRVGLTAPPCLRRVRALEDAGVIKGYHAELDAS
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHCCCCHH
KLGFAITVFALVSLKSQAEESLRQFEDHMRTLPEVRECHMLNGEIDFILKIVSKDLQSFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
EFLTSKLTPAPNVASVKTSLTIRTAKQVPGVPLED
HHHHHCCCCCCCCHHHHHHHEEEEHHHCCCCCCCC
>Mature Secondary Structure 
ATLDGIDRRLLAELQAEGRVTNVELAQRVGLTAPPCLRRVRALEDAGVIKGYHAELDAS
CCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHCCCCHH
KLGFAITVFALVSLKSQAEESLRQFEDHMRTLPEVRECHMLNGEIDFILKIVSKDLQSFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
EFLTSKLTPAPNVASVKTSLTIRTAKQVPGVPLED
HHHHHCCCCCCCCHHHHHHHEEEEHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]