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The map label for this gene is aroA

Identifier: 87199347

GI number: 87199347

Start: 1369010

End: 1370335

Strand: Reverse

Name: aroA

Synonym: Saro_1326

Alternate gene names: 87199347

Gene position: 1370335-1369010 (Counterclockwise)

Preceding gene: 87199351

Following gene: 87199346

Centisome position: 38.48

GC content: 70.14

Gene sequence:

>1326_bases
ATGCGCCCTCGCCGCTTCACCGCCAATGGCCCGCTCAAGGGCCGCATCGGCGTGCCCGGCGACAAGTCGATCAGCCACCG
CTCGATCATGCTCGGCGCGCTGGCAGTGGGCGAGACGCGCGTGACCGGCCTGCTCGAAGGCGAGGACGTCCTTTCCACCG
CCGCCGCGATGCGCGCGATGGGCGCGACGATCGAACGCGACGCGGACGGCATGTGGCACGTTCACGGCGTTGGCGTGGGC
GGCCTGCTCCAGCCGCAACAGGCGCTGGACATGGGCAATTCGGGCACGTCGACCCGCCTGCTGATGGGCCTTGTCGCAAC
CCACCCGATCACGGCGACGTTCGTGGGCGATGCTTCGCTGTCGAAGCGCCCGATGGGCCGCGTGATCGATCCGCTCTCGA
CGATGGGCGCCGAGTTCACCGCATCGCCGGGTGGCCGCCTGCCCCTTACCCTGCGCGGAATTTCACCTGCCGTGCCAATC
GAATACCGCCTCCCCGTCGCATCGGCGCAGGTGAAGAGCGCGGTCCTGCTCGCGGGCCTCAACACGCCCGGCGTGACCAC
GGTAATCGAACCGATCCCCACCCGCGACCATTCCGAACGCATGCTGCGCGGCTTCGGCGCGGAGCTGACCGTCGATGTCG
CCGCCGATGGCGCGCGCGTCATCAGGGTGCGCGGCGAGGCCGAACTCAAGCCGCAGGACATCGCCGTCCCCGGCGACCCG
TCATCCGCCGCGTTCTTCGTGGTGGCGGCGCTGCTGGTCGAAGGCTCGGACCTCGTCGTCGAGAACGTCGGCCTCAACCC
CACCCGCGCCGCGCTGTTCGACGTGCTGCGCCTGATGGGCGGCTCCATCGAGGAGCTGAACCGGCGCGAAGTGGGCGGCG
AACCGGTGGCGGACCTGCGCGTGCGCCACTCGCTGCTGACCGGCATCGATGTCGATCCCGCCGTAGTGCCGAGCATGGTC
GACGAATTCCCGGTGCTGTTCGTCGCCGCCGCCCTTGCCAAGGGCCGCACGGTGACGACCGGCCTCGAGGAACTGCGCGT
GAAGGAAAGCGACCGCATCAGCGCGATGCGCGCCGCGCTCGAACTGGCAGGCGCGACCGTCACCGAGACCGAGGACGGCC
TGATCATCGACGGCACCGGCGGCGACCCCCTGCCCGGCACCGCAGAGGGCGCGAGCGTCGTCACGCACCTCGACCACCGC
ATCGCGATGAGCATGGCGATTGCCGGCATCGCCAGCCGCAACGGCGTGGAAGTGGATGACACCCGCCCCATCGCCACCAG
CTTCCCGGTGTTCGAGAGCCTGCTGGAAAGCGCGACCAGGCCGTGA

Upstream 100 bases:

>100_bases
GCGCGTGTCGCTGTCAAAAGCCCCGCGCTTCAAACCGCACTTCGGCCCTGCCCTTCAGCGCGAAAGACGAAACTCCGTGT
CTTCCCACGACCCTGCCCTC

Downstream 100 bases:

>100_bases
TGTCCGACCTGCTCGTCAATGTGATCGGCTTTGCAGGGATGGCCTGTATCATCTTCGCCTACGGCTATTCGACCAAGCTG
GAGCGGCCCAATCCCTTCGT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MRPRRFTANGPLKGRIGVPGDKSISHRSIMLGALAVGETRVTGLLEGEDVLSTAAAMRAMGATIERDADGMWHVHGVGVG
GLLQPQQALDMGNSGTSTRLLMGLVATHPITATFVGDASLSKRPMGRVIDPLSTMGAEFTASPGGRLPLTLRGISPAVPI
EYRLPVASAQVKSAVLLAGLNTPGVTTVIEPIPTRDHSERMLRGFGAELTVDVAADGARVIRVRGEAELKPQDIAVPGDP
SSAAFFVVAALLVEGSDLVVENVGLNPTRAALFDVLRLMGGSIEELNRREVGGEPVADLRVRHSLLTGIDVDPAVVPSMV
DEFPVLFVAAALAKGRTVTTGLEELRVKESDRISAMRAALELAGATVTETEDGLIIDGTGGDPLPGTAEGASVVTHLDHR
IAMSMAIAGIASRNGVEVDDTRPIATSFPVFESLLESATRP

Sequences:

>Translated_441_residues
MRPRRFTANGPLKGRIGVPGDKSISHRSIMLGALAVGETRVTGLLEGEDVLSTAAAMRAMGATIERDADGMWHVHGVGVG
GLLQPQQALDMGNSGTSTRLLMGLVATHPITATFVGDASLSKRPMGRVIDPLSTMGAEFTASPGGRLPLTLRGISPAVPI
EYRLPVASAQVKSAVLLAGLNTPGVTTVIEPIPTRDHSERMLRGFGAELTVDVAADGARVIRVRGEAELKPQDIAVPGDP
SSAAFFVVAALLVEGSDLVVENVGLNPTRAALFDVLRLMGGSIEELNRREVGGEPVADLRVRHSLLTGIDVDPAVVPSMV
DEFPVLFVAAALAKGRTVTTGLEELRVKESDRISAMRAALELAGATVTETEDGLIIDGTGGDPLPGTAEGASVVTHLDHR
IAMSMAIAGIASRNGVEVDDTRPIATSFPVFESLLESATRP
>Mature_441_residues
MRPRRFTANGPLKGRIGVPGDKSISHRSIMLGALAVGETRVTGLLEGEDVLSTAAAMRAMGATIERDADGMWHVHGVGVG
GLLQPQQALDMGNSGTSTRLLMGLVATHPITATFVGDASLSKRPMGRVIDPLSTMGAEFTASPGGRLPLTLRGISPAVPI
EYRLPVASAQVKSAVLLAGLNTPGVTTVIEPIPTRDHSERMLRGFGAELTVDVAADGARVIRVRGEAELKPQDIAVPGDP
SSAAFFVVAALLVEGSDLVVENVGLNPTRAALFDVLRLMGGSIEELNRREVGGEPVADLRVRHSLLTGIDVDPAVVPSMV
DEFPVLFVAAALAKGRTVTTGLEELRVKESDRISAMRAALELAGATVTETEDGLIIDGTGGDPLPGTAEGASVVTHLDHR
IAMSMAIAGIASRNGVEVDDTRPIATSFPVFESLLESATRP

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=432, Percent_Identity=29.6296296296296, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320332, Length=437, Percent_Identity=27.9176201372998, Blast_Score=114, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_NOVAD (Q2G8Q3)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_496604.1
- ProteinModelPortal:   Q2G8Q3
- SMR:   Q2G8Q3
- STRING:   Q2G8Q3
- GeneID:   3917775
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_1326
- NMPDR:   fig|48935.1.peg.259
- eggNOG:   COG0128
- HOGENOM:   HBG646626
- OMA:   LSRNHTE
- ProtClustDB:   PRK02427
- BioCyc:   NARO279238:SARO_1326-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 45990; Mature: 45990

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPRRFTANGPLKGRIGVPGDKSISHRSIMLGALAVGETRVTGLLEGEDVLSTAAAMRAM
CCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEEEEECCHHEEEEECCHHHHHHHHHHHHH
GATIERDADGMWHVHGVGVGGLLQPQQALDMGNSGTSTRLLMGLVATHPITATFVGDASL
CCCCCCCCCCEEEEEEECCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCEEEEEECCCCC
SKRPMGRVIDPLSTMGAEFTASPGGRLPLTLRGISPAVPIEYRLPVASAQVKSAVLLAGL
CCCCHHHHHCCHHHCCCEEECCCCCCCCEEEECCCCCCCEEEECCCHHHHHHCEEEEEEC
NTPGVTTVIEPIPTRDHSERMLRGFGAELTVDVAADGARVIRVRGEAELKPQDIAVPGDP
CCCCCEEEECCCCCCCHHHHHHHHCCCEEEEEEECCCEEEEEEECCCCCCCCCEECCCCC
SSAAFFVVAALLVEGSDLVVENVGLNPTRAALFDVLRLMGGSIEELNRREVGGEPVADLR
CHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHH
VRHSLLTGIDVDPAVVPSMVDEFPVLFVAAALAKGRTVTTGLEELRVKESDRISAMRAAL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHCCCHHHHHHHHHHH
ELAGATVTETEDGLIIDGTGGDPLPGTAEGASVVTHLDHRIAMSMAIAGIASRNGVEVDD
HHHCCEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TRPIATSFPVFESLLESATRP
CCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MRPRRFTANGPLKGRIGVPGDKSISHRSIMLGALAVGETRVTGLLEGEDVLSTAAAMRAM
CCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEEEEECCHHEEEEECCHHHHHHHHHHHHH
GATIERDADGMWHVHGVGVGGLLQPQQALDMGNSGTSTRLLMGLVATHPITATFVGDASL
CCCCCCCCCCEEEEEEECCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCEEEEEECCCCC
SKRPMGRVIDPLSTMGAEFTASPGGRLPLTLRGISPAVPIEYRLPVASAQVKSAVLLAGL
CCCCHHHHHCCHHHCCCEEECCCCCCCCEEEECCCCCCCEEEECCCHHHHHHCEEEEEEC
NTPGVTTVIEPIPTRDHSERMLRGFGAELTVDVAADGARVIRVRGEAELKPQDIAVPGDP
CCCCCEEEECCCCCCCHHHHHHHHCCCEEEEEEECCCEEEEEEECCCCCCCCCEECCCCC
SSAAFFVVAALLVEGSDLVVENVGLNPTRAALFDVLRLMGGSIEELNRREVGGEPVADLR
CHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHH
VRHSLLTGIDVDPAVVPSMVDEFPVLFVAAALAKGRTVTTGLEELRVKESDRISAMRAAL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHCCCHHHHHHHHHHH
ELAGATVTETEDGLIIDGTGGDPLPGTAEGASVVTHLDHRIAMSMAIAGIASRNGVEVDD
HHHCCEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TRPIATSFPVFESLLESATRP
CCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA