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The map label for this gene is kdsB [H]

Identifier: 87199305

GI number: 87199305

Start: 1326432

End: 1327220

Strand: Reverse

Name: kdsB [H]

Synonym: Saro_1284

Alternate gene names: 87199305

Gene position: 1327220-1326432 (Counterclockwise)

Preceding gene: 87199306

Following gene: 87199303

Centisome position: 37.26

GC content: 69.96

Gene sequence:

>789_bases
ATGAAGGTTCTGGTCGTGATTCCCGCGCGTTACGGATCGCATCGCTTCCCAGGCAAGCCGCTCCACCCCTTGCGCAGGCA
CGATGGCAGCGCCGCTCCGCTGATCGAATGGACCTGGCGCGCGGGCGTGGCTGCGGCAGGCGCGGAGAATGTCGTGTTCG
CGACGGACGACGAGCGCATCGCGAGGGTCGCCAAGGGGTTCGGCGCGCGCGTGGCGCTAACGCCGGAAGGGTGCCGCAAC
GGAACCGAGCGCTGTGCGGCGGCTCTCGCGGCGATCGGACCGGACGGATGGGGCGGCGAAGCGGAAATCGTGGTCAACCT
GCAAGGCGACAGTCCACTCGTGCCGCCCGAAATGATCCACGCGCTGCTGGCCGCGTTCGACGACCCAGCGACCGCAGTCG
CCACGCCCTGCATCCGTTGCGACGAGGCGCAGGCACGCCTCGTGCTGGACGAATGCGCAGCCGGACGGGTAGGCGGGACG
TGCGTCGTAGCGCGGGGGGACGGTACGGCCGCATACTTCAGCAAGCGCCCGATCCCGTTCGGCGCGCCGTCGGCCATGCC
GCTGCGCCTGCACGTCGGCCTATACGCCTACCGCCGCGCCGCGCTTGACCGCTATGTGGCGCTGGGGCCGTGCGAACTGG
AACTGGCCGAGGGGCTGGAGCAACTGCGCTTCATACACGCGGGCCTGCCAGTGACGCTGGTGGACGTGCCCGCGCCGCCG
GGCGGGCTGTGGGAAGTGAACAACCCGGAAGATGTCCGGGTGGTCGAGGAAATGCTGCCGCAGGGGTGA

Upstream 100 bases:

>100_bases
GCTGCCTCGTGCGGGGCGGCATTGCCAGCAGGAGCGCGGTCGAAATGCTGGTCGACAATGTCACGGCGCGACTGCTCGCC
GCTTCCCCGAAGGTGCCCGC

Downstream 100 bases:

>100_bases
TGGCGGGAGGGCGCGCCCATACCAGCGCTCCCTCCCTGCCGGTTTTACTTGCCCTGCCAGTTGGGCTTGCGCTTCTCGGC
GAAAGCGGCGGCGCCTTCGC

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MKVLVVIPARYGSHRFPGKPLHPLRRHDGSAAPLIEWTWRAGVAAAGAENVVFATDDERIARVAKGFGARVALTPEGCRN
GTERCAAALAAIGPDGWGGEAEIVVNLQGDSPLVPPEMIHALLAAFDDPATAVATPCIRCDEAQARLVLDECAAGRVGGT
CVVARGDGTAAYFSKRPIPFGAPSAMPLRLHVGLYAYRRAALDRYVALGPCELELAEGLEQLRFIHAGLPVTLVDVPAPP
GGLWEVNNPEDVRVVEEMLPQG

Sequences:

>Translated_262_residues
MKVLVVIPARYGSHRFPGKPLHPLRRHDGSAAPLIEWTWRAGVAAAGAENVVFATDDERIARVAKGFGARVALTPEGCRN
GTERCAAALAAIGPDGWGGEAEIVVNLQGDSPLVPPEMIHALLAAFDDPATAVATPCIRCDEAQARLVLDECAAGRVGGT
CVVARGDGTAAYFSKRPIPFGAPSAMPLRLHVGLYAYRRAALDRYVALGPCELELAEGLEQLRFIHAGLPVTLVDVPAPP
GGLWEVNNPEDVRVVEEMLPQG
>Mature_262_residues
MKVLVVIPARYGSHRFPGKPLHPLRRHDGSAAPLIEWTWRAGVAAAGAENVVFATDDERIARVAKGFGARVALTPEGCRN
GTERCAAALAAIGPDGWGGEAEIVVNLQGDSPLVPPEMIHALLAAFDDPATAVATPCIRCDEAQARLVLDECAAGRVGGT
CVVARGDGTAAYFSKRPIPFGAPSAMPLRLHVGLYAYRRAALDRYVALGPCELELAEGLEQLRFIHAGLPVTLVDVPAPP
GGLWEVNNPEDVRVVEEMLPQG

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=268, Percent_Identity=31.7164179104478, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27734; Mature: 27734

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVVIPARYGSHRFPGKPLHPLRRHDGSAAPLIEWTWRAGVAAAGAENVVFATDDERI
CEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCEEEEHHCCCEEECCCCCEEEECCHHHH
ARVAKGFGARVALTPEGCRNGTERCAAALAAIGPDGWGGEAEIVVNLQGDSPLVPPEMIH
HHHHHCCCCEEEECCHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHH
ALLAAFDDPATAVATPCIRCDEAQARLVLDECAAGRVGGTCVVARGDGTAAYFSKRPIPF
HHHHHCCCCCHHHHCCCEECCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCCCCC
GAPSAMPLRLHVGLYAYRRAALDRYVALGPCELELAEGLEQLRFIHAGLPVTLVDVPAPP
CCCCCCEEEEEHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCC
GGLWEVNNPEDVRVVEEMLPQG
CCCEECCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKVLVVIPARYGSHRFPGKPLHPLRRHDGSAAPLIEWTWRAGVAAAGAENVVFATDDERI
CEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCEEEEHHCCCEEECCCCCEEEECCHHHH
ARVAKGFGARVALTPEGCRNGTERCAAALAAIGPDGWGGEAEIVVNLQGDSPLVPPEMIH
HHHHHCCCCEEEECCHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHH
ALLAAFDDPATAVATPCIRCDEAQARLVLDECAAGRVGGTCVVARGDGTAAYFSKRPIPF
HHHHHCCCCCHHHHCCCEECCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCCCCC
GAPSAMPLRLHVGLYAYRRAALDRYVALGPCELELAEGLEQLRFIHAGLPVTLVDVPAPP
CCCCCCEEEEEHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCC
GGLWEVNNPEDVRVVEEMLPQG
CCCEECCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA