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The map label for this gene is glmS [H]

Identifier: 87199224

GI number: 87199224

Start: 1249534

End: 1251357

Strand: Direct

Name: glmS [H]

Synonym: Saro_1202

Alternate gene names: 87199224

Gene position: 1249534-1251357 (Clockwise)

Preceding gene: 87199223

Following gene: 87199225

Centisome position: 35.08

GC content: 68.15

Gene sequence:

>1824_bases
ATGTGCGGAATCATCGGAATCGTCGGCAAGGAACAGGTTGCGGACCGGCTGGTCGACGGCCTGCGGCGGATGGAATACCG
CGGCTATGACAGCGCCGGCGTGTGCACCGTGGAAGGCGGCCGGCTGATCCGCCGTCGCGCCGAGGGCAAGCTGAACAACC
TGGTCGCGGAACTGGTGCGCAATCCCGCGTCGGGCCTGATCGGCATCGCGCATACTCGCTGGGCGACGCACGGCGCACCG
ACCACCAGCAACGCGCACCCCCATGCGACCGACGAGGTGGCGCTGGTCCACAACGGCATCATCGAGAACTTCAAGCCGCT
GCGCGAAGCCCTGATCGCGCGGGGGCGCAGGTTCGAGAGCGAGACCGATACCGAAGTGATCGCGCACCTGGTGTCCGAGC
AGGTCGAGGCGGGGCTTTCGCCGCAGGATGCGGTGAAGGCGGTACTGCCGCAACTGCGCGGCGCATTCGCCATCGCCGTG
GCCTTTCGCAGCCACGACGACATGCTGATCGGCGCGCGCCTGGGCTCGCCGCTGGTGGTTGGGTATGGCGAAGGCGAGAC
CTATCTGGGATCGGACGCCATCGCCCTGGCGCCGCTGACCCAGCGCATCGCCTATCTGGAGGAAGGCGACTGGGTCGTCG
TCAAGCGCGAGGGCGCGCAGATCTTCGATGCCGAGAACAAGCCGGTCACGCGCCCGATCGTGGCTTCGGGCGCGACGGCG
GCGGCGATCGAGAAGGGCAACTATCGCCACTTCATGCAGAAGGAAATCTTCGAGCAGCCCGCCGTCGTCGCCCAGACCTT
GCGCAGCTACCTGCGCCGCGTGGAGCAGACCGTGGCGCTGCCACAGATCGACTTCGACCTTGCCAGCATCAACCGCGTCA
CCATCGTCGCCTGCGGGACGAGCTACTATGCCGGCATGGTGGCGAAGTACTGGTTCGAACAGTTCGCCCGCCTGCCGGTG
GACATCGACGTGGCATCCGAGTTCCGTTACCGCGACCCGGTGCTCGAGCCGGGCGGGCTGGCGCTGTTCATCTCGCAGAG
CGGCGAGACCGCCGATACGCTGGCGGCGCTGCGCCACTGCAAGGCGGCCGGACAGACCATCGCGGTCGTCGTCAACGTGC
CGACAAGCTCGATGGCGCGCGAGGCGGACCTGCTGCTGCCGACCCACGCGGGCCCGGAAATCGGCGTCGCTTCGACCAAG
GCGTTCACCTGCCAGCTTGCCGTCCTCGCCGCGCTCGCCGCGCACCTTGCAGTAAAGCGCGGGCGGCTGACGCGCGAGGA
GGAGGCGGCCATCGTAGAGCAGCTTGTCGAGACGCCGGCCGCGCTCAATGCCGCGCTTTCGCACGACGAGGAAATCGCGG
GCATGGCCCACCTCATCGCGCCCGCGCGCGACGTGCTCTACCTCGGGCGCGGGCCGGACTATCCGCTGGCGCTGGAAGGC
GCGCTCAAGCTCAAGGAAATCAGCTACATCCATGCCGAGGGTTACGCCTCGGGCGAGATGAAGCACGGGCCCATCGCGCT
GATCGACGAGGCCGTGCCGGTGATCGTGCTGGCGCCGAGCGGCCCCCTGTTCGAGAAGACGGTCAGCAACATGCAGGAAG
TGCGGGCGCGGGGCGGCAAGATCGTGCTCATTTCCGACGCGGAAGGGCTGGCCGAGGCGGGCGAGGGGTGCCTCGCCACG
ATCGAAATGCCGAAGGTCCACCCGCTGATCGCGCCGCTGGTCTACGCCGTGCCGGTGCAGCTTCTCGCCTACCACGTGGC
CGTGGCCAAGGGCACCGACGTCGACCAGCCGCGCAACCTTGCCAAGAGCGTGACGGTGGAGTGA

Upstream 100 bases:

>100_bases
CAACGGAAGCATTCTGGTTACACGAAATACCAAGGATTTTCCGGCCACCATGCCGGGGATTCGCGTACCCTATACCCTCT
AGCGAAAGTGCCATTTCCCC

Downstream 100 bases:

>100_bases
GCCCGGCGGCGATGCGGATTGCCCTGTACGAGCCGGAGATTGCCGGAAACGTTGGCGCGGTCATGCGCCTCGGTGCGTGC
CTTGGCGTTAATGTCGACCT

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MCGIIGIVGKEQVADRLVDGLRRMEYRGYDSAGVCTVEGGRLIRRRAEGKLNNLVAELVRNPASGLIGIAHTRWATHGAP
TTSNAHPHATDEVALVHNGIIENFKPLREALIARGRRFESETDTEVIAHLVSEQVEAGLSPQDAVKAVLPQLRGAFAIAV
AFRSHDDMLIGARLGSPLVVGYGEGETYLGSDAIALAPLTQRIAYLEEGDWVVVKREGAQIFDAENKPVTRPIVASGATA
AAIEKGNYRHFMQKEIFEQPAVVAQTLRSYLRRVEQTVALPQIDFDLASINRVTIVACGTSYYAGMVAKYWFEQFARLPV
DIDVASEFRYRDPVLEPGGLALFISQSGETADTLAALRHCKAAGQTIAVVVNVPTSSMAREADLLLPTHAGPEIGVASTK
AFTCQLAVLAALAAHLAVKRGRLTREEEAAIVEQLVETPAALNAALSHDEEIAGMAHLIAPARDVLYLGRGPDYPLALEG
ALKLKEISYIHAEGYASGEMKHGPIALIDEAVPVIVLAPSGPLFEKTVSNMQEVRARGGKIVLISDAEGLAEAGEGCLAT
IEMPKVHPLIAPLVYAVPVQLLAYHVAVAKGTDVDQPRNLAKSVTVE

Sequences:

>Translated_607_residues
MCGIIGIVGKEQVADRLVDGLRRMEYRGYDSAGVCTVEGGRLIRRRAEGKLNNLVAELVRNPASGLIGIAHTRWATHGAP
TTSNAHPHATDEVALVHNGIIENFKPLREALIARGRRFESETDTEVIAHLVSEQVEAGLSPQDAVKAVLPQLRGAFAIAV
AFRSHDDMLIGARLGSPLVVGYGEGETYLGSDAIALAPLTQRIAYLEEGDWVVVKREGAQIFDAENKPVTRPIVASGATA
AAIEKGNYRHFMQKEIFEQPAVVAQTLRSYLRRVEQTVALPQIDFDLASINRVTIVACGTSYYAGMVAKYWFEQFARLPV
DIDVASEFRYRDPVLEPGGLALFISQSGETADTLAALRHCKAAGQTIAVVVNVPTSSMAREADLLLPTHAGPEIGVASTK
AFTCQLAVLAALAAHLAVKRGRLTREEEAAIVEQLVETPAALNAALSHDEEIAGMAHLIAPARDVLYLGRGPDYPLALEG
ALKLKEISYIHAEGYASGEMKHGPIALIDEAVPVIVLAPSGPLFEKTVSNMQEVRARGGKIVLISDAEGLAEAGEGCLAT
IEMPKVHPLIAPLVYAVPVQLLAYHVAVAKGTDVDQPRNLAKSVTVE
>Mature_607_residues
MCGIIGIVGKEQVADRLVDGLRRMEYRGYDSAGVCTVEGGRLIRRRAEGKLNNLVAELVRNPASGLIGIAHTRWATHGAP
TTSNAHPHATDEVALVHNGIIENFKPLREALIARGRRFESETDTEVIAHLVSEQVEAGLSPQDAVKAVLPQLRGAFAIAV
AFRSHDDMLIGARLGSPLVVGYGEGETYLGSDAIALAPLTQRIAYLEEGDWVVVKREGAQIFDAENKPVTRPIVASGATA
AAIEKGNYRHFMQKEIFEQPAVVAQTLRSYLRRVEQTVALPQIDFDLASINRVTIVACGTSYYAGMVAKYWFEQFARLPV
DIDVASEFRYRDPVLEPGGLALFISQSGETADTLAALRHCKAAGQTIAVVVNVPTSSMAREADLLLPTHAGPEIGVASTK
AFTCQLAVLAALAAHLAVKRGRLTREEEAAIVEQLVETPAALNAALSHDEEIAGMAHLIAPARDVLYLGRGPDYPLALEG
ALKLKEISYIHAEGYASGEMKHGPIALIDEAVPVIVLAPSGPLFEKTVSNMQEVRARGGKIVLISDAEGLAEAGEGCLAT
IEMPKVHPLIAPLVYAVPVQLLAYHVAVAKGTDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=689, Percent_Identity=37.300435413643, Blast_Score=402, Evalue=1e-112,
Organism=Homo sapiens, GI205277386, Length=687, Percent_Identity=37.117903930131, Blast_Score=396, Evalue=1e-110,
Organism=Escherichia coli, GI1790167, Length=612, Percent_Identity=51.3071895424837, Blast_Score=598, Evalue=1e-172,
Organism=Escherichia coli, GI87082251, Length=313, Percent_Identity=23.961661341853, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1788651, Length=264, Percent_Identity=27.6515151515151, Blast_Score=82, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17539970, Length=723, Percent_Identity=34.3015214384509, Blast_Score=382, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17532899, Length=434, Percent_Identity=37.5576036866359, Blast_Score=282, Evalue=4e-76,
Organism=Caenorhabditis elegans, GI17532897, Length=434, Percent_Identity=37.5576036866359, Blast_Score=281, Evalue=5e-76,
Organism=Saccharomyces cerevisiae, GI6322745, Length=451, Percent_Identity=37.4722838137472, Blast_Score=266, Evalue=1e-71,
Organism=Saccharomyces cerevisiae, GI6323731, Length=437, Percent_Identity=29.5194508009153, Blast_Score=187, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6323730, Length=231, Percent_Identity=35.0649350649351, Blast_Score=124, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6323958, Length=172, Percent_Identity=28.4883720930233, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21357745, Length=686, Percent_Identity=36.8804664723032, Blast_Score=418, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 65049; Mature: 65049

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIIGIVGKEQVADRLVDGLRRMEYRGYDSAGVCTVEGGRLIRRRAEGKLNNLVAELVR
CCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHCCHHHHHHHHHHH
NPASGLIGIAHTRWATHGAPTTSNAHPHATDEVALVHNGIIENFKPLREALIARGRRFES
CCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ETDTEVIAHLVSEQVEAGLSPQDAVKAVLPQLRGAFAIAVAFRSHDDMLIGARLGSPLVV
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCCCEEE
GYGEGETYLGSDAIALAPLTQRIAYLEEGDWVVVKREGAQIFDAENKPVTRPIVASGATA
EECCCCCEECCCCEEEHHHHHHHHHEECCCEEEEEECCCEEEECCCCCCCCCHHCCCCCH
AAIEKGNYRHFMQKEIFEQPAVVAQTLRSYLRRVEQTVALPQIDFDLASINRVTIVACGT
HHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCEEEEEEECC
SYYAGMVAKYWFEQFARLPVDIDVASEFRYRDPVLEPGGLALFISQSGETADTLAALRHC
HHHHHHHHHHHHHHHHCCCCEEEHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
KAAGQTIAVVVNVPTSSMAREADLLLPTHAGPEIGVASTKAFTCQLAVLAALAAHLAVKR
HHCCCEEEEEEECCCHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GRLTREEEAAIVEQLVETPAALNAALSHDEEIAGMAHLIAPARDVLYLGRGPDYPLALEG
CCCCCHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHCCCCCEEEECCCCCCCEEECC
ALKLKEISYIHAEGYASGEMKHGPIALIDEAVPVIVLAPSGPLFEKTVSNMQEVRARGGK
CEEEHHEEEEEECCCCCCCCCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHCCCE
IVLISDAEGLAEAGEGCLATIEMPKVHPLIAPLVYAVPVQLLAYHVAVAKGTDVDQPRNL
EEEEECCCCHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
AKSVTVE
HHHCCCC
>Mature Secondary Structure
MCGIIGIVGKEQVADRLVDGLRRMEYRGYDSAGVCTVEGGRLIRRRAEGKLNNLVAELVR
CCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHCCHHHHHHHHHHH
NPASGLIGIAHTRWATHGAPTTSNAHPHATDEVALVHNGIIENFKPLREALIARGRRFES
CCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ETDTEVIAHLVSEQVEAGLSPQDAVKAVLPQLRGAFAIAVAFRSHDDMLIGARLGSPLVV
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCCCEEE
GYGEGETYLGSDAIALAPLTQRIAYLEEGDWVVVKREGAQIFDAENKPVTRPIVASGATA
EECCCCCEECCCCEEEHHHHHHHHHEECCCEEEEEECCCEEEECCCCCCCCCHHCCCCCH
AAIEKGNYRHFMQKEIFEQPAVVAQTLRSYLRRVEQTVALPQIDFDLASINRVTIVACGT
HHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCEEEEEEECC
SYYAGMVAKYWFEQFARLPVDIDVASEFRYRDPVLEPGGLALFISQSGETADTLAALRHC
HHHHHHHHHHHHHHHHCCCCEEEHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
KAAGQTIAVVVNVPTSSMAREADLLLPTHAGPEIGVASTKAFTCQLAVLAALAAHLAVKR
HHCCCEEEEEEECCCHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GRLTREEEAAIVEQLVETPAALNAALSHDEEIAGMAHLIAPARDVLYLGRGPDYPLALEG
CCCCCHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHCCCCCEEEECCCCCCCEEECC
ALKLKEISYIHAEGYASGEMKHGPIALIDEAVPVIVLAPSGPLFEKTVSNMQEVRARGGK
CEEEHHEEEEEECCCCCCCCCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHCCCE
IVLISDAEGLAEAGEGCLATIEMPKVHPLIAPLVYAVPVQLLAYHVAVAKGTDVDQPRNL
EEEEECCCCHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
AKSVTVE
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA