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The map label for this gene is tesB [H]

Identifier: 87199086

GI number: 87199086

Start: 1107109

End: 1108011

Strand: Reverse

Name: tesB [H]

Synonym: Saro_1064

Alternate gene names: 87199086

Gene position: 1108011-1107109 (Counterclockwise)

Preceding gene: 87199087

Following gene: 87199080

Centisome position: 31.11

GC content: 67.11

Gene sequence:

>903_bases
ATGACCGAGAACGAAAATCCGAGTCCGCAGGAACTGGTGGACGGCCTGCTGACGCTGCTCGACGTGAAGGACCATGGTGG
CGACCGCTTCGAAGGGCGGCGCAAGATCGGCGGCGTGGGGCGCGTCTTCGGCGGGCAGGTCATCGGCCAGGCGCTCGCCA
GTGCAGAGCGCACTGTGCCCGATGACCGTCCGGTCCATTCGCTTCACGCCTATTTCCTGCGCGGCGGTAGCGAGGACCAC
GAAATCGACTTCAAGGTGGAGCGAGACCTCGACGGCGGCTCGTTCTCCAACCGGCGCGTGGTGGCAAGCCAGCTTGGCAA
GCCGATCCTCAACATGGTGGCATCGTTCCACAAGCGCGAGGACGGCGTCTATCATGCGGACGCGATGCCTACGGTCGCCC
CGCCCGAGAATCTGCCGAGCGAAGTGGAATTGCGGCGCAAGTATGCCGACAAGGTGCCCGAGGCGATGCGCCGCCAGATG
CTTCAGCCCCGCCCCATCGAACTGCGCCCGCTCGAAGCGCGCCACTGGATGGACAGCGGCCCCCGCGATCCGGTTTCGCA
CACGTGGTTCCGCTCGGTCGCCTCGCTGCCCGACGATCCGCGCATCCACCGCGCGGTGCTGGCCTATGCCAGCGACATGA
CGCTGCTCGGCACCTCCACGTTGCCCCACGACATAAGCTGGTCCAAGGGCAACATGATGGGGGCCAGCCTGGACCACGCA
GTGTGGTTCCACGACGATTTCCGCGCGGACGAATGGCTGCTCTACGCCTGCGACAGCCCGTGGGCGGGCCGCGCGCGCGG
TTTCAACCGGGGCCGGATCTACACGCGCGAGGGCAGGCTCGTCGCCAGCGTCGCGCAGGAAGGGCTGATCCGCCCGATCA
CGCGAAAGCCCAGGGAAGGCTGA

Upstream 100 bases:

>100_bases
ACAGGGCCAAGGCGATGTGCTGGCGGCTCTACGGCAAGGTACGTGGGCTGCGCTGACGCATACCGTTGACGTAAACGGGA
GCTCGGTTCATCGAACGCAC

Downstream 100 bases:

>100_bases
TCAGCGCGGCGGACAGGCCGGTCCGGCAATCTTCGGCTGCGCCACCATCGCGAAGACAACGCGGCCAAGCGCGGCAGGAC
CGGGGCTTGCCGCAAGGTCG

Product: palmitoyl-CoA hydrolase

Products: Hydrolyzed acyl-CoA thioesters [C]

Alternate protein names: Acyl-CoA thioesterase II; TEII [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTENENPSPQELVDGLLTLLDVKDHGGDRFEGRRKIGGVGRVFGGQVIGQALASAERTVPDDRPVHSLHAYFLRGGSEDH
EIDFKVERDLDGGSFSNRRVVASQLGKPILNMVASFHKREDGVYHADAMPTVAPPENLPSEVELRRKYADKVPEAMRRQM
LQPRPIELRPLEARHWMDSGPRDPVSHTWFRSVASLPDDPRIHRAVLAYASDMTLLGTSTLPHDISWSKGNMMGASLDHA
VWFHDDFRADEWLLYACDSPWAGRARGFNRGRIYTREGRLVASVAQEGLIRPITRKPREG

Sequences:

>Translated_300_residues
MTENENPSPQELVDGLLTLLDVKDHGGDRFEGRRKIGGVGRVFGGQVIGQALASAERTVPDDRPVHSLHAYFLRGGSEDH
EIDFKVERDLDGGSFSNRRVVASQLGKPILNMVASFHKREDGVYHADAMPTVAPPENLPSEVELRRKYADKVPEAMRRQM
LQPRPIELRPLEARHWMDSGPRDPVSHTWFRSVASLPDDPRIHRAVLAYASDMTLLGTSTLPHDISWSKGNMMGASLDHA
VWFHDDFRADEWLLYACDSPWAGRARGFNRGRIYTREGRLVASVAQEGLIRPITRKPREG
>Mature_299_residues
TENENPSPQELVDGLLTLLDVKDHGGDRFEGRRKIGGVGRVFGGQVIGQALASAERTVPDDRPVHSLHAYFLRGGSEDHE
IDFKVERDLDGGSFSNRRVVASQLGKPILNMVASFHKREDGVYHADAMPTVAPPENLPSEVELRRKYADKVPEAMRRQML
QPRPIELRPLEARHWMDSGPRDPVSHTWFRSVASLPDDPRIHRAVLAYASDMTLLGTSTLPHDISWSKGNMMGASLDHAV
WFHDDFRADEWLLYACDSPWAGRARGFNRGRIYTREGRLVASVAQEGLIRPITRKPREG

Specific function: Can hydrolyze a broad range of acyl-CoA thioesters. Its physiological function is not known [H]

COG id: COG1946

COG function: function code I; Acyl-CoA thioesterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C/M/P thioester hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI34577075, Length=284, Percent_Identity=39.7887323943662, Blast_Score=200, Evalue=1e-51,
Organism=Escherichia coli, GI1786657, Length=262, Percent_Identity=43.8931297709924, Blast_Score=233, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI71988741, Length=294, Percent_Identity=37.7551020408163, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17558508, Length=282, Percent_Identity=36.5248226950355, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI115532456, Length=277, Percent_Identity=35.3790613718412, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17531889, Length=277, Percent_Identity=35.3790613718412, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17531885, Length=277, Percent_Identity=35.3790613718412, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71982224, Length=276, Percent_Identity=34.4202898550725, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI212645202, Length=265, Percent_Identity=30.9433962264151, Blast_Score=115, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003703 [H]

Pfam domain/function: PF02551 Acyl_CoA_thio [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 33715; Mature: 33584

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTENENPSPQELVDGLLTLLDVKDHGGDRFEGRRKIGGVGRVFGGQVIGQALASAERTVP
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCC
DDRPVHSLHAYFLRGGSEDHEIDFKVERDLDGGSFSNRRVVASQLGKPILNMVASFHKRE
CCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHC
DGVYHADAMPTVAPPENLPSEVELRRKYADKVPEAMRRQMLQPRPIELRPLEARHWMDSG
CCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHCCCC
PRDPVSHTWFRSVASLPDDPRIHRAVLAYASDMTLLGTSTLPHDISWSKGNMMGASLDHA
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCE
VWFHDDFRADEWLLYACDSPWAGRARGFNRGRIYTREGRLVASVAQEGLIRPITRKPREG
EEECCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TENENPSPQELVDGLLTLLDVKDHGGDRFEGRRKIGGVGRVFGGQVIGQALASAERTVP
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCC
DDRPVHSLHAYFLRGGSEDHEIDFKVERDLDGGSFSNRRVVASQLGKPILNMVASFHKRE
CCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHC
DGVYHADAMPTVAPPENLPSEVELRRKYADKVPEAMRRQMLQPRPIELRPLEARHWMDSG
CCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHCCCC
PRDPVSHTWFRSVASLPDDPRIHRAVLAYASDMTLLGTSTLPHDISWSKGNMMGASLDHA
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCE
VWFHDDFRADEWLLYACDSPWAGRARGFNRGRIYTREGRLVASVAQEGLIRPITRKPREG
EEECCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA thioesters [C]

Specific reaction: Hydrolyzes a broad range of acyl-CoA thioesters [C]

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]