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The map label for this gene is purN [H]

Identifier: 87198920

GI number: 87198920

Start: 954970

End: 955557

Strand: Reverse

Name: purN [H]

Synonym: Saro_0898

Alternate gene names: 87198920

Gene position: 955557-954970 (Counterclockwise)

Preceding gene: 87198921

Following gene: 87198919

Centisome position: 26.83

GC content: 67.01

Gene sequence:

>588_bases
TTGGCTGAACGCACGCCCGTCGCGGTCTTCATCTCCGGCAGCGGCACCAACATGGCCGCGCTGCTCTATGCCTCGCGCAT
GGCGGGCTGCCCCTACGAGATCGCGCTCGTCCTCTCGAACAATCCCGATGCTTCCGGGCTCAGGTTGGCCCAGGCCGAAA
GCGTTCCCACCTTCTGCCTGCCCCACAAGGGCATTCCCCGCGCCGAGCATGACGCCCTGATGGAAGCCGAAGTGCTCAAG
TCGGGCGCGCAGCTCATCGCGCTCGCCGGCTACATGCGCATCCTCAGCGCGGAATTCGTCGCGCGCTGGGAAGGGCGAAT
GCTCAACATCCACCCTTCGCTCCTGCCGAAGTACAAGGGCCTGCACACCCACGACCGCGCGATCGAGGCCGGCGACACCC
ACGGCGGCTGCACGGTCCACCTGGTGACGGCGGAACTCGACGACGGCCCGATCCTCGGCCAGCTTCCCGTCGCCATTCTC
CCCGGCGACACCGGCGAAACCCTTGCCGCCCGCGTGCTCTTTGCCGAACACCAGCTCTATTCGCGGGTGCTCTCGACCTT
CGCCATCCAGCACCAGACGAGCGTCTGA

Upstream 100 bases:

>100_bases
GTCTACCGCGTCGGCACCATCGTGAAGGGCGAAAAGGGCTGCACCGTCACCGGAAGCGCCGAGACCTGGTCCGCCCGCTC
GGCCTGGGAAGCCACCCACA

Downstream 100 bases:

>100_bases
CACCATGCTCACGACCATCCGCCGGATTTACGCACACACCGCTCTGCAATCGTTTGTTGAAGCAAGCGGCGGCCTCTTCG
TCGTCGGCTTTCTGGTGCGA

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MAERTPVAVFISGSGTNMAALLYASRMAGCPYEIALVLSNNPDASGLRLAQAESVPTFCLPHKGIPRAEHDALMEAEVLK
SGAQLIALAGYMRILSAEFVARWEGRMLNIHPSLLPKYKGLHTHDRAIEAGDTHGGCTVHLVTAELDDGPILGQLPVAIL
PGDTGETLAARVLFAEHQLYSRVLSTFAIQHQTSV

Sequences:

>Translated_195_residues
MAERTPVAVFISGSGTNMAALLYASRMAGCPYEIALVLSNNPDASGLRLAQAESVPTFCLPHKGIPRAEHDALMEAEVLK
SGAQLIALAGYMRILSAEFVARWEGRMLNIHPSLLPKYKGLHTHDRAIEAGDTHGGCTVHLVTAELDDGPILGQLPVAIL
PGDTGETLAARVLFAEHQLYSRVLSTFAIQHQTSV
>Mature_194_residues
AERTPVAVFISGSGTNMAALLYASRMAGCPYEIALVLSNNPDASGLRLAQAESVPTFCLPHKGIPRAEHDALMEAEVLKS
GAQLIALAGYMRILSAEFVARWEGRMLNIHPSLLPKYKGLHTHDRAIEAGDTHGGCTVHLVTAELDDGPILGQLPVAILP
GDTGETLAARVLFAEHQLYSRVLSTFAIQHQTSV

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=187, Percent_Identity=41.1764705882353, Blast_Score=148, Evalue=3e-36,
Organism=Homo sapiens, GI209869995, Length=187, Percent_Identity=41.1764705882353, Blast_Score=148, Evalue=3e-36,
Organism=Homo sapiens, GI209869993, Length=187, Percent_Identity=41.1764705882353, Blast_Score=148, Evalue=3e-36,
Organism=Escherichia coli, GI1788846, Length=183, Percent_Identity=42.0765027322404, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1787483, Length=184, Percent_Identity=31.5217391304348, Blast_Score=90, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17567511, Length=179, Percent_Identity=40.2234636871508, Blast_Score=133, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6320616, Length=198, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24582400, Length=187, Percent_Identity=43.3155080213904, Blast_Score=151, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR001555
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 20878; Mature: 20747

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERTPVAVFISGSGTNMAALLYASRMAGCPYEIALVLSNNPDASGLRLAQAESVPTFCL
CCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEECCCCCCCEEC
PHKGIPRAEHDALMEAEVLKSGAQLIALAGYMRILSAEFVARWEGRMLNIHPSLLPKYKG
CCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHCCCCCC
LHTHDRAIEAGDTHGGCTVHLVTAELDDGPILGQLPVAILPGDTGETLAARVLFAEHQLY
CCCCCCEEECCCCCCCEEEEEEEEECCCCCEECCCCEEEECCCCCHHHHHHHHHHHHHHH
SRVLSTFAIQHQTSV
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
AERTPVAVFISGSGTNMAALLYASRMAGCPYEIALVLSNNPDASGLRLAQAESVPTFCL
CCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEECCCCCCCEEC
PHKGIPRAEHDALMEAEVLKSGAQLIALAGYMRILSAEFVARWEGRMLNIHPSLLPKYKG
CCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHCCCCCC
LHTHDRAIEAGDTHGGCTVHLVTAELDDGPILGQLPVAILPGDTGETLAARVLFAEHQLY
CCCCCCEEECCCCCCCEEEEEEEEECCCCCEECCCCEEEECCCCCHHHHHHHHHHHHHHH
SRVLSTFAIQHQTSV
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]