Click here to switch to the map view.

The map label for this gene is ligD [H]

Identifier: 87198230

GI number: 87198230

Start: 212005

End: 212925

Strand: Direct

Name: ligD [H]

Synonym: Saro_0205

Alternate gene names: 87198230

Gene position: 212005-212925 (Clockwise)

Preceding gene: 87198227

Following gene: 87198231

Centisome position: 5.95

GC content: 66.78

Gene sequence:

>921_bases
GTGCAAAGTTTCGAGAACGAGATCGCCTTCATCACGGGCGGTGCTTCGGGTGCAGGCTTCGGGCAGGCACAGGTCTTCGG
CCGGGCTGGCGCGAAGATCGTCGTCGCCGACGTCCGCGCCGAAGCGGTGGAGCGGGCCGTTGCCGCGCTGAAGGCCGAAG
GCATCGTCGCTCACGGCCTCGTCCTCGATATCACCGACCGCCAGGCCTACGCCGGCGCCGCCGACGAGGTCGAGCAGGTC
TTCGGCGCGGCGCCCACGCTTCTGTTCAACACCGCTGGCGTGAACAGCTTCGGCCCGGTCGAGGATACCTCCTACGACGA
TTTCGACTGGATCGTCGGCGTCAACCTGGGCGGCGTCATCAACGGCATGGTCACGTTCGTGCCGCGCATGATCGCCAGCG
GCAGGCCCGGCCACATCGTCACCACTTCCTCGCTCGGCGGCCTCATGGGCAGCGCGCTTGCCGCACCCTACTCGGCGGCG
AAGGCAGCCGTCATCAACCTGATGGAAAGCTATCGCCAGGGCCTCGACAAGCACGGCATCGGCGTTTCCGTGCTGTGTCC
GGCCAACATCAAGTCGAACATCGCGGAAGCCAGCCGCCTGCGGCCGGCGCAGTTCGGCAAGAGCGGTTATGTCGAAAACG
AGGAGTCGATCGCCTCGCTGCATTCGATCCACCAGCACGGCATGGACCCGGTCGAACTGGCAGAGCACGTCAAGGCGGGC
ATCGTGGCCAATCAACTCTACATCATCCCCTATCCCGAAGCGAAGGACGGGCTGCGCCAGCACTTCGATGCGATCGTGGA
CGCGGTCCTGCCGCTGGAGGCCGATCCCGAGGGCGCCCGCGCCCGTACCGAGGCCCTCAACGCCTGGGCGGCCGACCGCG
CGCGCGTCTTCATGGAGAAGAACGCCGCCCAGAAGGCCTGA

Upstream 100 bases:

>100_bases
AGCGGCAAACCGGGCGCGAGTCACCCACGGCGTTCACTTGCTCCGGCAAGCGGAATTTTGTAAGCAACACTAACAATAAT
CTGCGAGAGAGGATCACCGC

Downstream 100 bases:

>100_bases
AGTCCAGAAGGGCTGAAGTCAACTTCGCTTGACATCCTCTCAATTTTGGTCAAGTTTCCTTGTCATCAGATCAAGGAGGC
TTGACCAATGCTTGCCAGGA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MQSFENEIAFITGGASGAGFGQAQVFGRAGAKIVVADVRAEAVERAVAALKAEGIVAHGLVLDITDRQAYAGAADEVEQV
FGAAPTLLFNTAGVNSFGPVEDTSYDDFDWIVGVNLGGVINGMVTFVPRMIASGRPGHIVTTSSLGGLMGSALAAPYSAA
KAAVINLMESYRQGLDKHGIGVSVLCPANIKSNIAEASRLRPAQFGKSGYVENEESIASLHSIHQHGMDPVELAEHVKAG
IVANQLYIIPYPEAKDGLRQHFDAIVDAVLPLEADPEGARARTEALNAWAADRARVFMEKNAAQKA

Sequences:

>Translated_306_residues
MQSFENEIAFITGGASGAGFGQAQVFGRAGAKIVVADVRAEAVERAVAALKAEGIVAHGLVLDITDRQAYAGAADEVEQV
FGAAPTLLFNTAGVNSFGPVEDTSYDDFDWIVGVNLGGVINGMVTFVPRMIASGRPGHIVTTSSLGGLMGSALAAPYSAA
KAAVINLMESYRQGLDKHGIGVSVLCPANIKSNIAEASRLRPAQFGKSGYVENEESIASLHSIHQHGMDPVELAEHVKAG
IVANQLYIIPYPEAKDGLRQHFDAIVDAVLPLEADPEGARARTEALNAWAADRARVFMEKNAAQKA
>Mature_306_residues
MQSFENEIAFITGGASGAGFGQAQVFGRAGAKIVVADVRAEAVERAVAALKAEGIVAHGLVLDITDRQAYAGAADEVEQV
FGAAPTLLFNTAGVNSFGPVEDTSYDDFDWIVGVNLGGVINGMVTFVPRMIASGRPGHIVTTSSLGGLMGSALAAPYSAA
KAAVINLMESYRQGLDKHGIGVSVLCPANIKSNIAEASRLRPAQFGKSGYVENEESIASLHSIHQHGMDPVELAEHVKAG
IVANQLYIIPYPEAKDGLRQHFDAIVDAVLPLEADPEGARARTEALNAWAADRARVFMEKNAAQKA

Specific function: Catalyzes the C alpha dehydrogenation of arylglycerol- beta-aryl ether (C alpha alcohol type) (compound IV) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=244, Percent_Identity=29.0983606557377, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI210032110, Length=224, Percent_Identity=27.2321428571429, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI7706318, Length=198, Percent_Identity=30.3030303030303, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI157739938, Length=275, Percent_Identity=26.1818181818182, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI66933014, Length=168, Percent_Identity=29.7619047619048, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI32483357, Length=229, Percent_Identity=27.5109170305677, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI33667109, Length=204, Percent_Identity=27.4509803921569, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI40807363, Length=198, Percent_Identity=28.7878787878788, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI5031737, Length=198, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI87082100, Length=242, Percent_Identity=30.1652892561983, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1790717, Length=189, Percent_Identity=29.1005291005291, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787335, Length=198, Percent_Identity=29.2929292929293, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1786701, Length=187, Percent_Identity=27.807486631016, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789057, Length=252, Percent_Identity=26.5873015873016, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=253, Percent_Identity=28.8537549407115, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=235, Percent_Identity=27.2340425531915, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=194, Percent_Identity=27.8350515463918, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=193, Percent_Identity=30.0518134715026, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=192, Percent_Identity=26.0416666666667, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=190, Percent_Identity=27.3684210526316, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=195, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=188, Percent_Identity=27.6595744680851, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=192, Percent_Identity=24.4791666666667, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=208, Percent_Identity=25.4807692307692, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17536651, Length=205, Percent_Identity=24.8780487804878, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6320089, Length=197, Percent_Identity=28.4263959390863, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581726, Length=218, Percent_Identity=29.3577981651376, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24639444, Length=187, Percent_Identity=30.4812834224599, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI221510726, Length=195, Percent_Identity=31.2820512820513, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21358495, Length=256, Percent_Identity=27.734375, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21355631, Length=170, Percent_Identity=30.5882352941176, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640492, Length=199, Percent_Identity=26.1306532663317, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 32112; Mature: 32112

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSFENEIAFITGGASGAGFGQAQVFGRAGAKIVVADVRAEAVERAVAALKAEGIVAHGL
CCCCCCCEEEEECCCCCCCCCHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCEEECCE
VLDITDRQAYAGAADEVEQVFGAAPTLLFNTAGVNSFGPVEDTSYDDFDWIVGVNLGGVI
EEEECCCHHHCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEECCCCHHH
NGMVTFVPRMIASGRPGHIVTTSSLGGLMGSALAAPYSAAKAAVINLMESYRQGLDKHGI
HHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHCCC
GVSVLCPANIKSNIAEASRLRPAQFGKSGYVENEESIASLHSIHQHGMDPVELAEHVKAG
CEEEEECCCHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
IVANQLYIIPYPEAKDGLRQHFDAIVDAVLPLEADPEGARARTEALNAWAADRARVFMEK
HEECEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NAAQKA
HCCCCC
>Mature Secondary Structure
MQSFENEIAFITGGASGAGFGQAQVFGRAGAKIVVADVRAEAVERAVAALKAEGIVAHGL
CCCCCCCEEEEECCCCCCCCCHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCEEECCE
VLDITDRQAYAGAADEVEQVFGAAPTLLFNTAGVNSFGPVEDTSYDDFDWIVGVNLGGVI
EEEECCCHHHCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEECCCCHHH
NGMVTFVPRMIASGRPGHIVTTSSLGGLMGSALAAPYSAAKAAVINLMESYRQGLDKHGI
HHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHCCC
GVSVLCPANIKSNIAEASRLRPAQFGKSGYVENEESIASLHSIHQHGMDPVELAEHVKAG
CEEEEECCCHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
IVANQLYIIPYPEAKDGLRQHFDAIVDAVLPLEADPEGARARTEALNAWAADRARVFMEK
HEECEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NAAQKA
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1744051; 8495726; 7764263 [H]