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The map label for this gene is 87198173

Identifier: 87198173

GI number: 87198173

Start: 147894

End: 149066

Strand: Direct

Name: 87198173

Synonym: Saro_0147

Alternate gene names: NA

Gene position: 147894-149066 (Clockwise)

Preceding gene: 87198172

Following gene: 87198175

Centisome position: 4.15

GC content: 67.35

Gene sequence:

>1173_bases
ATGGAGAAGGCGGAGAGGCCGTATGACGTTGTCGTCTACGGGGCGACGGGGTTCACCGGGCGACTGGTCGCGGAGTATCT
GGCGCGGCATTACGGGCAGGAAGGGCCGCGTTGGGCCATGGCCGGGCGATCTGGCGCGAAACTGGCAGAAGTGCGCGCCC
TGATCGAGGCGCCCAAGAACACGCCGCTGATCGTGGCCGATGCCTCCGATCCCGCCAGCCTTGCCGACATGGTCCGCCAG
GCCAAGGTCGTTCTTACCACAGTAGGGCCGTACCAGCTCTATGGCGAGCCATTGCTGGCGGCCTGCGTCGCGGCGGGGAC
CGACTATGCGGACCTGTGCGGCGAGCCGGTGTGGATGCGGCAGATGATCGACAAGTATGGCGACGATGCCCGGCATTCGG
GCGCGCGCATCTGTTTCTCGTCCGGGTTCGATTCGATCCCGTTCGACCTGGGCGTGCTCATGTTGCAGAAGGAAGCGGTC
GCCCGGTTTGGCCGCCCTGCCCCGCGCGTCAAGGGGCGGGTCCGGGGCATGAAGGGCGGCGCTTCGGGCGGCACGGCGGC
AAGCCTGAAGGCCACGCTCGCGGCGCTCGGCAAGGACCCGTCGCTCATCCCGCTGATGGCCAGCCCATTCTGCCTGACCC
CTGGTTTCGAGGGGCCGGCCCAGCCAGCCGGCGACAAGGTGCAGCACGACGACGCGTTGGGGAGCTGGGAAACGCCCTTC
ATCATGGCGGCGATCAACACCAAGAACGTTCATCGCACCAACGCCTTGCTCGGCCACGCCTGGGGCAAGGACTTCGTCTA
TGACGAGATGGTACTGACCGGTCCCGGCGAACAGGGCAAGGCGGTGGCCGAACACATGGCGAAGACGCCGATGATCGGCC
GCCCCGACGATCCGCTGCCCGGCGAAGGGCCGTCGAAGGAAGAGCGCGAGACCGGCTTCTACGACGTGCTCTTCGTCGGG
GAGATGCCTGGCGGGGAGACGATTCGCTATGGTGTGAAGGGCCGCTATGACCCCGGCTATGGATCGACAAGCCGGATGAT
CGCGGAGACCGGCATCGCGCTGCTTTCGAGTACTGCGGCCGGGGGAATCGGTACGCCCGGCGCGATCCTGGGCGAAACGC
TGGTCGCGCGGCTGCGCGCCCATGCCGAGATTGCGTTCGCGCCCGAGGACTGA

Upstream 100 bases:

>100_bases
GGCGCTGGCGCTTCACGCTTAACCCCGCACTTAAATCCGGTTGCAATCGCCACTGATTCGGCCAAGCTTCGCCGCACAAG
AACAACAGGCGGAGAGGCTG

Downstream 100 bases:

>100_bases
CCTCAAAAGCGACGAAAGCCCGCCTGCCGCTACGGAGGGGATCCGCGGCAGGCGGGCTCGTCTACCGCGCCCGAATCTGG
ATAGGGGGGATCAGGCGACG

Product: saccharopine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MEKAERPYDVVVYGATGFTGRLVAEYLARHYGQEGPRWAMAGRSGAKLAEVRALIEAPKNTPLIVADASDPASLADMVRQ
AKVVLTTVGPYQLYGEPLLAACVAAGTDYADLCGEPVWMRQMIDKYGDDARHSGARICFSSGFDSIPFDLGVLMLQKEAV
ARFGRPAPRVKGRVRGMKGGASGGTAASLKATLAALGKDPSLIPLMASPFCLTPGFEGPAQPAGDKVQHDDALGSWETPF
IMAAINTKNVHRTNALLGHAWGKDFVYDEMVLTGPGEQGKAVAEHMAKTPMIGRPDDPLPGEGPSKEERETGFYDVLFVG
EMPGGETIRYGVKGRYDPGYGSTSRMIAETGIALLSSTAAGGIGTPGAILGETLVARLRAHAEIAFAPED

Sequences:

>Translated_390_residues
MEKAERPYDVVVYGATGFTGRLVAEYLARHYGQEGPRWAMAGRSGAKLAEVRALIEAPKNTPLIVADASDPASLADMVRQ
AKVVLTTVGPYQLYGEPLLAACVAAGTDYADLCGEPVWMRQMIDKYGDDARHSGARICFSSGFDSIPFDLGVLMLQKEAV
ARFGRPAPRVKGRVRGMKGGASGGTAASLKATLAALGKDPSLIPLMASPFCLTPGFEGPAQPAGDKVQHDDALGSWETPF
IMAAINTKNVHRTNALLGHAWGKDFVYDEMVLTGPGEQGKAVAEHMAKTPMIGRPDDPLPGEGPSKEERETGFYDVLFVG
EMPGGETIRYGVKGRYDPGYGSTSRMIAETGIALLSSTAAGGIGTPGAILGETLVARLRAHAEIAFAPED
>Mature_390_residues
MEKAERPYDVVVYGATGFTGRLVAEYLARHYGQEGPRWAMAGRSGAKLAEVRALIEAPKNTPLIVADASDPASLADMVRQ
AKVVLTTVGPYQLYGEPLLAACVAAGTDYADLCGEPVWMRQMIDKYGDDARHSGARICFSSGFDSIPFDLGVLMLQKEAV
ARFGRPAPRVKGRVRGMKGGASGGTAASLKATLAALGKDPSLIPLMASPFCLTPGFEGPAQPAGDKVQHDDALGSWETPF
IMAAINTKNVHRTNALLGHAWGKDFVYDEMVLTGPGEQGKAVAEHMAKTPMIGRPDDPLPGEGPSKEERETGFYDVLFVG
EMPGGETIRYGVKGRYDPGYGSTSRMIAETGIALLSSTAAGGIGTPGAILGETLVARLRAHAEIAFAPED

Specific function: Unknown

COG id: COG3268

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI55770836, Length=171, Percent_Identity=42.6900584795322, Blast_Score=128, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI32567112, Length=156, Percent_Identity=47.4358974358974, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17560066, Length=156, Percent_Identity=47.4358974358974, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71991033, Length=212, Percent_Identity=35.8490566037736, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24646278, Length=161, Percent_Identity=36.0248447204969, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24644140, Length=156, Percent_Identity=37.1794871794872, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24644142, Length=156, Percent_Identity=37.1794871794872, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21356081, Length=156, Percent_Identity=37.1794871794872, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: NA

Molecular weight: Translated: 41241; Mature: 41241

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKAERPYDVVVYGATGFTGRLVAEYLARHYGQEGPRWAMAGRSGAKLAEVRALIEAPKN
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHCCCC
TPLIVADASDPASLADMVRQAKVVLTTVGPYQLYGEPLLAACVAAGTDYADLCGEPVWMR
CCEEEECCCCCHHHHHHHHHCEEEEEECCCHHHHCCHHHHHHHHCCCCHHHHCCCHHHHH
QMIDKYGDDARHSGARICFSSGFDSIPFDLGVLMLQKEAVARFGRPAPRVKGRVRGMKGG
HHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCC
ASGGTAASLKATLAALGKDPSLIPLMASPFCLTPGFEGPAQPAGDKVQHDDALGSWETPF
CCCCCHHHHHHHHHHHCCCCCEEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCE
IMAAINTKNVHRTNALLGHAWGKDFVYDEMVLTGPGEQGKAVAEHMAKTPMIGRPDDPLP
EEEEECCCCCHHHHHHHHHCCCCCCEECCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCC
GEGPSKEERETGFYDVLFVGEMPGGETIRYGVKGRYDPGYGSTSRMIAETGIALLSSTAA
CCCCCCHHHHCCCEEEEEEECCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
GGIGTPGAILGETLVARLRAHAEIAFAPED
CCCCCCHHHHHHHHHHHHHHCCEEEECCCC
>Mature Secondary Structure
MEKAERPYDVVVYGATGFTGRLVAEYLARHYGQEGPRWAMAGRSGAKLAEVRALIEAPKN
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHCCCC
TPLIVADASDPASLADMVRQAKVVLTTVGPYQLYGEPLLAACVAAGTDYADLCGEPVWMR
CCEEEECCCCCHHHHHHHHHCEEEEEECCCHHHHCCHHHHHHHHCCCCHHHHCCCHHHHH
QMIDKYGDDARHSGARICFSSGFDSIPFDLGVLMLQKEAVARFGRPAPRVKGRVRGMKGG
HHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCC
ASGGTAASLKATLAALGKDPSLIPLMASPFCLTPGFEGPAQPAGDKVQHDDALGSWETPF
CCCCCHHHHHHHHHHHCCCCCEEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCE
IMAAINTKNVHRTNALLGHAWGKDFVYDEMVLTGPGEQGKAVAEHMAKTPMIGRPDDPLP
EEEEECCCCCHHHHHHHHHCCCCCCEECCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCC
GEGPSKEERETGFYDVLFVGEMPGGETIRYGVKGRYDPGYGSTSRMIAETGIALLSSTAA
CCCCCCHHHHCCCEEEEEEECCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
GGIGTPGAILGETLVARLRAHAEIAFAPED
CCCCCCHHHHHHHHHHHHHHCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]