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The map label for this gene is lig [H]

Identifier: 87198093

GI number: 87198093

Start: 68777

End: 69850

Strand: Direct

Name: lig [H]

Synonym: Saro_0067

Alternate gene names: 87198093

Gene position: 68777-69850 (Clockwise)

Preceding gene: 87198092

Following gene: 87198094

Centisome position: 1.93

GC content: 69.46

Gene sequence:

>1074_bases
ATGCGCCAGGGCCACCCGGCACCAAGGGCACTGGAACCCGAAGCCGCGACCGGCCATTTCATGACAATGGCCCCGCCCTT
TTCCTGGCTTCGACCCGAACCGCACGGCCTTCACGTGGTGCCGGCCGACGCCTGGGTCGATCCGGCGCGTGCCGTCGACA
CCGCCCTCGTCACCCACGGCCACGCCGATCATGCGCGCGGCGGGCACGGCCGCACGGTCGCCACACCCGAGACGCTGGCG
ATCATGGCGCTGCGCTATGGCGTCATGGAGGCAGGCTCGCAGCCGGTGGGTTATGGCGAGACGGTTACGCTGCGCGGCGA
CGTGCGGGCGACCTATTACCCGGCGGGCCATGTCCTGGGTTCCGCCCAGATCCTGCTTGAACACGCGGGCGAGCGGGTCA
TCATCACGGGCGACTACAAGCGTCGCCCCGATCCCACCTGCCCGCCCTTCGAGGTCGTGCCCTGCGACGTGTTCGTCACC
GAAGCGACCTTCGGCCTTCCGGTCTTCCGCCACCCGCCCATCGCGCAGGAGATGGGCAAACTTCTGGCCGCCCGCGAGAA
CGACGCGGGCCGCTGCGTCCTCGTGGGCGCCTATGCCCTGGGCAAGGCGCAGCGCGTCATCGCGGAGCTGCGCGCCGCAG
GCTTCGCCGACACCATCTGGCTCCATGGCGCCATGGAGCGGATGTGCCGTCTCTATGAGGATCACGGCGTCGACCTGGGC
GATCTCAGGCCGGTGGCGGGCGTGCCCAAGGCGGCGCTGGCCAATGCCGTGATCGTCTGCCCGCCATCGGCGCTCAACGA
CCGCTGGAGCCGACGCCTTCCCGATCCGGTGACCGCAATGGCATCTGGCTGGATGCGGGTCCGCCAGCGCGTTCGCCAGC
GCAACGTCGAACTGCCGCTGGTCATTTCCGACCACGCCGACTGGGACGAGCTGACCGCCACCATCGCGGATGTGAACCCG
TCCGAGACATGGATCACCCACGGGCGGGAGGAGGCGCTCCTGCGATGGTGCGAACTCACCCAGCGCCGGGCGCGGGCACT
GGCGCTTGCAGGATACGAGGACGAGGATGATTGA

Upstream 100 bases:

>100_bases
GCGATACCACCGCCGAGGAACCCAACGCCGACGAGGCCTGATTCTCCGCTCGAGACCTGACAGAAGAAGGCCTGCCTTTC
GGGGCGGGCCTTTTTTCTGC

Downstream 100 bases:

>100_bases
GGCTGGCCCGTTCCAGCCCGGCTCGGGATGGTCACTCTCCGCGTGGCGGAGAAGGCCTGCATGAACCGCTTTGCCGCCCT
GCTCGACGCGCTCGTGCTCA

Product: putative mRNA 3-end processing factor

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MRQGHPAPRALEPEAATGHFMTMAPPFSWLRPEPHGLHVVPADAWVDPARAVDTALVTHGHADHARGGHGRTVATPETLA
IMALRYGVMEAGSQPVGYGETVTLRGDVRATYYPAGHVLGSAQILLEHAGERVIITGDYKRRPDPTCPPFEVVPCDVFVT
EATFGLPVFRHPPIAQEMGKLLAARENDAGRCVLVGAYALGKAQRVIAELRAAGFADTIWLHGAMERMCRLYEDHGVDLG
DLRPVAGVPKAALANAVIVCPPSALNDRWSRRLPDPVTAMASGWMRVRQRVRQRNVELPLVISDHADWDELTATIADVNP
SETWITHGREEALLRWCELTQRRARALALAGYEDEDD

Sequences:

>Translated_357_residues
MRQGHPAPRALEPEAATGHFMTMAPPFSWLRPEPHGLHVVPADAWVDPARAVDTALVTHGHADHARGGHGRTVATPETLA
IMALRYGVMEAGSQPVGYGETVTLRGDVRATYYPAGHVLGSAQILLEHAGERVIITGDYKRRPDPTCPPFEVVPCDVFVT
EATFGLPVFRHPPIAQEMGKLLAARENDAGRCVLVGAYALGKAQRVIAELRAAGFADTIWLHGAMERMCRLYEDHGVDLG
DLRPVAGVPKAALANAVIVCPPSALNDRWSRRLPDPVTAMASGWMRVRQRVRQRNVELPLVISDHADWDELTATIADVNP
SETWITHGREEALLRWCELTQRRARALALAGYEDEDD
>Mature_357_residues
MRQGHPAPRALEPEAATGHFMTMAPPFSWLRPEPHGLHVVPADAWVDPARAVDTALVTHGHADHARGGHGRTVATPETLA
IMALRYGVMEAGSQPVGYGETVTLRGDVRATYYPAGHVLGSAQILLEHAGERVIITGDYKRRPDPTCPPFEVVPCDVFVT
EATFGLPVFRHPPIAQEMGKLLAARENDAGRCVLVGAYALGKAQRVIAELRAAGFADTIWLHGAMERMCRLYEDHGVDLG
DLRPVAGVPKAALANAVIVCPPSALNDRWSRRLPDPVTAMASGWMRVRQRVRQRNVELPLVISDHADWDELTATIADVNP
SETWITHGREEALLRWCELTQRRARALALAGYEDEDD

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent DNA ligase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323307, Length=220, Percent_Identity=30.4545454545455, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011108 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N; PF07521 RMMBL [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 39098; Mature: 39098

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQGHPAPRALEPEAATGHFMTMAPPFSWLRPEPHGLHVVPADAWVDPARAVDTALVTHG
CCCCCCCCCCCCCCCCCCCEEEECCCCHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCC
HADHARGGHGRTVATPETLAIMALRYGVMEAGSQPVGYGETVTLRGDVRATYYPAGHVLG
CCCCCCCCCCCEECCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEECCHHHHH
SAQILLEHAGERVIITGDYKRRPDPTCPPFEVVPCDVFVTEATFGLPVFRHPPIAQEMGK
HHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEECEEEEECHHHCCCCCCCCCHHHHHHH
LLAARENDAGRCVLVGAYALGKAQRVIAELRAAGFADTIWLHGAMERMCRLYEDHGVDLG
HHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHH
DLRPVAGVPKAALANAVIVCPPSALNDRWSRRLPDPVTAMASGWMRVRQRVRQRNVELPL
CCCCCCCCCHHHHCCEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
VISDHADWDELTATIADVNPSETWITHGREEALLRWCELTQRRARALALAGYEDEDD
EECCCCCHHHHHEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHEEEEECCCCCCC
>Mature Secondary Structure
MRQGHPAPRALEPEAATGHFMTMAPPFSWLRPEPHGLHVVPADAWVDPARAVDTALVTHG
CCCCCCCCCCCCCCCCCCCEEEECCCCHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCC
HADHARGGHGRTVATPETLAIMALRYGVMEAGSQPVGYGETVTLRGDVRATYYPAGHVLG
CCCCCCCCCCCEECCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEECCHHHHH
SAQILLEHAGERVIITGDYKRRPDPTCPPFEVVPCDVFVTEATFGLPVFRHPPIAQEMGK
HHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEECEEEEECHHHCCCCCCCCCHHHHHHH
LLAARENDAGRCVLVGAYALGKAQRVIAELRAAGFADTIWLHGAMERMCRLYEDHGVDLG
HHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHH
DLRPVAGVPKAALANAVIVCPPSALNDRWSRRLPDPVTAMASGWMRVRQRVRQRNVELPL
CCCCCCCCCHHHHCCEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
VISDHADWDELTATIADVNPSETWITHGREEALLRWCELTQRRARALALAGYEDEDD
EECCCCCHHHHHEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA