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The map label for this gene is mtnA [H]

Identifier: 86751795

GI number: 86751795

Start: 5315549

End: 5316673

Strand: Reverse

Name: mtnA [H]

Synonym: RPB_4697

Alternate gene names: 86751795

Gene position: 5316673-5315549 (Counterclockwise)

Preceding gene: 86751796

Following gene: 86751794

Centisome position: 99.72

GC content: 68.62

Gene sequence:

>1125_bases
ATGAAAGTCGACGGCATTCATACCCGCTCCATCTGGCTCGAGCCCGACGGCTGGACCGTCGCGGCGATCGATCAGCGCCG
GCTGCCGCATGAATATGTCGTGGCGCGGCTGACCAATTGCGACCGCGCGGCGGACGCGATCCGCGCGATGCTGGTGCGCG
GCGCGCCGCTGATCGGGGCGACGGCGGCCTACGGCGTGGCGCTGGCGATGCGCGAGGACGCCTCCGATGCGGCGCTGGCC
ATCGCCTACAATAAGCTGATCGCGACGCGGCCGACTGCGATCAATCTGAAATGGGCGCTCGACGAGATGCGCCGTGCGCT
CGCCCCGGTGAAGCCGGCCGACCGCGTCGCCGCCGCTTATCAGCGCGCCGCCGAAATCGCCGACGAGGACGTCGCCATCA
ACCAGGCGATCGGCGCCCACGGGCTGAAGCTGATCGAAGCCATCGCGGCCAGGAAGAAGCCCGGCGAGCGCGTCAACGTG
CTGACGCATTGCAATGCCGGCTGGCTCGCCACCGTCGACTGGGGCACCGCGACTGCGCCGATCTATCAGGCGTTCGACAA
GGGCATTGCGATCCACGTCTATGCCGACGAGACCCGGCCGCGCAATCAGGGCGCCTCGCTCACCGCCTGGGAGCTCGGCC
ATCACGGCGTCGATCATACGGTCATCCCGGACAACACCGGCGGCCATCTGATGCAGCACGGCATGGTCGACCTCTGCATC
GTCGGCACCGACCGCGTCACCGCCGACGGCGACGTCTGCAACAAGATCGGCACCTACCTCAAGGCGCTCGCCGCGCGCGA
CAACAACGTGCCCTTCTACGTGGCATTGCCGTCGCCGACCATCGACTTCACCATCCACGACGGCGTGAAGGAGATCCCGA
TCGAGCAGCGCGACGCCGCCGAGGTCACCGACATGACCGGCCGCACCCATGACGGCCGGATCGAGACCGTACGGATCGTG
CCGCAGGGTTCGAAGGTCGCCAATTACGGCTTCGACGTCACGCCCTCGCGCCTCGTCACCGGCCTGATCACCGAGCGCGG
CGTGCTGAAACCCGACCGGGCGTCGCTGGCGGCGGCGTTCCCGGAGCGGGTGGCGCGCGAGCAGGAACCGTTGCCGGCGT
CGTGA

Upstream 100 bases:

>100_bases
AATCCATCCTCTTCAATGATGGATGCCCGGGTCAAGCCCGGGCATGACGAGTTGAGAAGTTGCGGTCTCATTGTCAGGCT
AGTTGTTCTGAGGTGGCAAG

Downstream 100 bases:

>100_bases
GTTCATCTCACGAACCCAGAAGAACCGCAGCCCGATACCTGTTGTGACGCCCGTCGCCCTCGCGCGGCCGAAGGTCACGC
GCGGTTCTGACGAAACCACT

Product: methylthioribose-1-phosphate isomerase

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MKVDGIHTRSIWLEPDGWTVAAIDQRRLPHEYVVARLTNCDRAADAIRAMLVRGAPLIGATAAYGVALAMREDASDAALA
IAYNKLIATRPTAINLKWALDEMRRALAPVKPADRVAAAYQRAAEIADEDVAINQAIGAHGLKLIEAIAARKKPGERVNV
LTHCNAGWLATVDWGTATAPIYQAFDKGIAIHVYADETRPRNQGASLTAWELGHHGVDHTVIPDNTGGHLMQHGMVDLCI
VGTDRVTADGDVCNKIGTYLKALAARDNNVPFYVALPSPTIDFTIHDGVKEIPIEQRDAAEVTDMTGRTHDGRIETVRIV
PQGSKVANYGFDVTPSRLVTGLITERGVLKPDRASLAAAFPERVAREQEPLPAS

Sequences:

>Translated_374_residues
MKVDGIHTRSIWLEPDGWTVAAIDQRRLPHEYVVARLTNCDRAADAIRAMLVRGAPLIGATAAYGVALAMREDASDAALA
IAYNKLIATRPTAINLKWALDEMRRALAPVKPADRVAAAYQRAAEIADEDVAINQAIGAHGLKLIEAIAARKKPGERVNV
LTHCNAGWLATVDWGTATAPIYQAFDKGIAIHVYADETRPRNQGASLTAWELGHHGVDHTVIPDNTGGHLMQHGMVDLCI
VGTDRVTADGDVCNKIGTYLKALAARDNNVPFYVALPSPTIDFTIHDGVKEIPIEQRDAAEVTDMTGRTHDGRIETVRIV
PQGSKVANYGFDVTPSRLVTGLITERGVLKPDRASLAAAFPERVAREQEPLPAS
>Mature_374_residues
MKVDGIHTRSIWLEPDGWTVAAIDQRRLPHEYVVARLTNCDRAADAIRAMLVRGAPLIGATAAYGVALAMREDASDAALA
IAYNKLIATRPTAINLKWALDEMRRALAPVKPADRVAAAYQRAAEIADEDVAINQAIGAHGLKLIEAIAARKKPGERVNV
LTHCNAGWLATVDWGTATAPIYQAFDKGIAIHVYADETRPRNQGASLTAWELGHHGVDHTVIPDNTGGHLMQHGMVDLCI
VGTDRVTADGDVCNKIGTYLKALAARDNNVPFYVALPSPTIDFTIHDGVKEIPIEQRDAAEVTDMTGRTHDGRIETVRIV
PQGSKVANYGFDVTPSRLVTGLITERGVLKPDRASLAAAFPERVAREQEPLPAS

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=360, Percent_Identity=37.2222222222222, Blast_Score=185, Evalue=7e-47,
Organism=Homo sapiens, GI23943880, Length=170, Percent_Identity=44.7058823529412, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17557462, Length=345, Percent_Identity=33.0434782608696, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6325375, Length=394, Percent_Identity=29.9492385786802, Blast_Score=152, Evalue=8e-38,
Organism=Drosophila melanogaster, GI21357667, Length=349, Percent_Identity=38.9684813753582, Blast_Score=184, Evalue=7e-47,
Organism=Drosophila melanogaster, GI24651647, Length=349, Percent_Identity=38.9684813753582, Blast_Score=184, Evalue=7e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 40398; Mature: 40398

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVDGIHTRSIWLEPDGWTVAAIDQRRLPHEYVVARLTNCDRAADAIRAMLVRGAPLIGA
CCCCCEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
TAAYGVALAMREDASDAALAIAYNKLIATRPTAINLKWALDEMRRALAPVKPADRVAAAY
HHHHHEEEEEECCCCCCEEEEEEHHHHCCCCCEEEEEEHHHHHHHHHCCCCCHHHHHHHH
QRAAEIADEDVAINQAIGAHGLKLIEAIAARKKPGERVNVLTHCNAGWLATVDWGTATAP
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCCHH
IYQAFDKGIAIHVYADETRPRNQGASLTAWELGHHGVDHTVIPDNTGGHLMQHGMVDLCI
HHHHHHCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCEECCCCCCCHHHHCCCEEEEE
VGTDRVTADGDVCNKIGTYLKALAARDNNVPFYVALPSPTIDFTIHDGVKEIPIEQRDAA
EECCCEECCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCHHHCCCCCCCCH
EVTDMTGRTHDGRIETVRIVPQGSKVANYGFDVTPSRLVTGLITERGVLKPDRASLAAAF
HHHHCCCCCCCCCEEEEEEEECCCEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHH
PERVAREQEPLPAS
HHHHHHCCCCCCCC
>Mature Secondary Structure
MKVDGIHTRSIWLEPDGWTVAAIDQRRLPHEYVVARLTNCDRAADAIRAMLVRGAPLIGA
CCCCCEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
TAAYGVALAMREDASDAALAIAYNKLIATRPTAINLKWALDEMRRALAPVKPADRVAAAY
HHHHHEEEEEECCCCCCEEEEEEHHHHCCCCCEEEEEEHHHHHHHHHCCCCCHHHHHHHH
QRAAEIADEDVAINQAIGAHGLKLIEAIAARKKPGERVNVLTHCNAGWLATVDWGTATAP
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCCHH
IYQAFDKGIAIHVYADETRPRNQGASLTAWELGHHGVDHTVIPDNTGGHLMQHGMVDLCI
HHHHHHCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCEECCCCCCCHHHHCCCEEEEE
VGTDRVTADGDVCNKIGTYLKALAARDNNVPFYVALPSPTIDFTIHDGVKEIPIEQRDAA
EECCCEECCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCHHHCCCCCCCCH
EVTDMTGRTHDGRIETVRIVPQGSKVANYGFDVTPSRLVTGLITERGVLKPDRASLAAAF
HHHHCCCCCCCCCEEEEEEEECCCEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHH
PERVAREQEPLPAS
HHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA