Click here to switch to the map view.

The map label for this gene is virA [H]

Identifier: 86751763

GI number: 86751763

Start: 5276893

End: 5278905

Strand: Direct

Name: virA [H]

Synonym: RPB_4665

Alternate gene names: 86751763

Gene position: 5276893-5278905 (Clockwise)

Preceding gene: 86751755

Following gene: 86751764

Centisome position: 98.97

GC content: 67.06

Gene sequence:

>2013_bases
ATGGTCGGGCTGGTGCGCGCGGTCCCGATCCGCTGGCGCATCCTGTCGATCGCGGCGCTGAACTCGCTGGTGGTGCTGAT
CCTCGCCAGCATGATCTGGAGCGGCGCGCGGGTGCTGAGCTCGGCCTGGGACGACGTCCGCCAGGTCCGCGAATCCGACA
AAGTCCTGGCGCTGCTGGAGAGCGAGACCAGCCGGCTGCAGAACCTGATCCACCGCTACATCAATCAGCCGAGCCCGGAC
CTGTTCGCCGAAATCCTGCTGCTGCGCGAGGCGGTGCTGGGCACGCTCACCAATCGCGCATCGACCGACCCGATGCTGTC
GGGATCGGTCGCCGAGCTCGAGCGCGTGACCGAACGCTTCCTCAACGGCTTCGGCGACCTGCGCGCGCTGCAGGGCAAGA
TCAAGGACACCTACGAAAACCAGGTGCAGGGGCCGGCGCGCGACATCGCCGGGCTGTATTCGATCATCGAGGGCGCGACC
GGGCGGCGCGATGCGGCGATCTGGCCGCCGCTCGGCCGCTCGCGCGAGGCCTTCACGGCGATGTTGGTGGCGGCCAATTC
GTACTATCTGTCGCTGTCCAAACAGGCCGCCGAGGACGCCCGTCGCAACACCGAGACGATCGAGCGCACCGTGCCGGTGA
TGATCGAGTTCGCCGACAACGACCTGCAGAAGATGGCGCTGCAGCGGCTGAAAGCCCGCGTCGCCGCCCTCCGCGACGGA
CTGCAGACGCTGTCGGATCAGCTCGCGAGCCGCAGCGATCTGCTGCGCAATGCGATCGACGCCAGCCAGGCCTCGACCAT
CGGCGCGATCGATGCGCTCTCGGTGAAGATGCGCCAGCGCGAACAGAAAGCGCAGGAGACGTTCGACCGGACGCTCACCG
GCATCTCGCGCAAGGTGCTGTGGATCGCGGTGATCTTCATCGGCGTGATCATGATCGTCGGCACCCTGATCGCGCTCAGC
ATTCGGCTGCCTCTGCAACAGATTTTGGCGGCGATGCACGCGATCACCTCCGGCGACTACGGCCGCCGCGTCGCCGGCAC
CGAAGCCCGCGACGAAGTCGGCGCGATGGCCCGCGCGGTCGAGGTGTTCCGCGAGAACGCCATCGACAAGCGCCGGGCCG
AAGACGATCTGCGCGCCTCCAAGGAGAAGGCCGAGAGCGCGCTGCTCGAATTGAATGCCGCGCAGCAGAATTTGATCGAC
GCCGAACGGCTGGCGGCGCTCGGCGGACTCGTGGCCGGCGTCGCCCACGAGGTCAACAACCCGATCGGAATCAGCCTGAC
GGTAGCGTCGAGCTTCAGCCGCAAGACGACGATGTTCGAGGCGGATCTGAAAGGCGATGCGCCGCTGCGGCGGTCGCAGC
TCGACGAATTCGTCCGCTCCTCCCGCGACGCCGCGCAGCAGTTGGTCGCCAACCTGCAACGCGCCGCCGAACTGATCCAG
TCGTTCAAACAGGTCGCGGTCGACCGCTCCCACGCCGAACGCCGGCAATTCAATCTGCACGAGGCCACCGACCAGATCGT
CGCCAGCCTCAAGCCGGTGCTGAAACGGGCGCCGATCGAGCTCGCGATCGACGTGCCCGACGGCCTGGTGATCGACGGCT
ATCCGGGCGCTTACGGCCAGATCCTGACCAACCTGTTCCTCAACGCCGCCAACCACGCCTTCGCCGACGGCCGCGCCGGC
CGGATCGCCATCACCGCGCGACCACGCGGCGACGACGTCGAGATCGTGTTCGCCGACAACGGCGCCGGCATGACCCCCGA
CGTGCAGCGCCAGGCGTTCGACCCGTTCTTCACCACCCGCCGCAACGAAGGCGGCACCGGGCTCGGCCTGCACATCGTTT
ACAATCTGGTCACCCAGCAGCTCGGCGGGCGGATGATGCTGGAATCAAGGCTGGGACAAGGCACGACTTTTCGCATTATC
ATGCCCCGCACCGCCACCGGCGGGCCGACCGACGCCGACACGCCCATCGACGGAAATGTGAAATGGCCGACCAGGACGAT
ATCCTCCAGCTGA

Upstream 100 bases:

>100_bases
GCAGCGCTCACCATCCGCAAGGCCGAATGAGTTGGACCCGGTAGACCAGCGCCAGGACAACAGCAGCGACGCGCAAGCGA
GCCTTGCGAGCCGGTCCGGC

Downstream 100 bases:

>100_bases
TCGAAGATACCGAGCCCGGGCCCGAGCCGTCGAACACCAAGCGGTGGAAGATCGCGGTGATCGACGACGATCCCGCCGTC
CACGAGGGCACCCGCTTCGC

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: WHR virA [H]

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
MVGLVRAVPIRWRILSIAALNSLVVLILASMIWSGARVLSSAWDDVRQVRESDKVLALLESETSRLQNLIHRYINQPSPD
LFAEILLLREAVLGTLTNRASTDPMLSGSVAELERVTERFLNGFGDLRALQGKIKDTYENQVQGPARDIAGLYSIIEGAT
GRRDAAIWPPLGRSREAFTAMLVAANSYYLSLSKQAAEDARRNTETIERTVPVMIEFADNDLQKMALQRLKARVAALRDG
LQTLSDQLASRSDLLRNAIDASQASTIGAIDALSVKMRQREQKAQETFDRTLTGISRKVLWIAVIFIGVIMIVGTLIALS
IRLPLQQILAAMHAITSGDYGRRVAGTEARDEVGAMARAVEVFRENAIDKRRAEDDLRASKEKAESALLELNAAQQNLID
AERLAALGGLVAGVAHEVNNPIGISLTVASSFSRKTTMFEADLKGDAPLRRSQLDEFVRSSRDAAQQLVANLQRAAELIQ
SFKQVAVDRSHAERRQFNLHEATDQIVASLKPVLKRAPIELAIDVPDGLVIDGYPGAYGQILTNLFLNAANHAFADGRAG
RIAITARPRGDDVEIVFADNGAGMTPDVQRQAFDPFFTTRRNEGGTGLGLHIVYNLVTQQLGGRMMLESRLGQGTTFRII
MPRTATGGPTDADTPIDGNVKWPTRTISSS

Sequences:

>Translated_670_residues
MVGLVRAVPIRWRILSIAALNSLVVLILASMIWSGARVLSSAWDDVRQVRESDKVLALLESETSRLQNLIHRYINQPSPD
LFAEILLLREAVLGTLTNRASTDPMLSGSVAELERVTERFLNGFGDLRALQGKIKDTYENQVQGPARDIAGLYSIIEGAT
GRRDAAIWPPLGRSREAFTAMLVAANSYYLSLSKQAAEDARRNTETIERTVPVMIEFADNDLQKMALQRLKARVAALRDG
LQTLSDQLASRSDLLRNAIDASQASTIGAIDALSVKMRQREQKAQETFDRTLTGISRKVLWIAVIFIGVIMIVGTLIALS
IRLPLQQILAAMHAITSGDYGRRVAGTEARDEVGAMARAVEVFRENAIDKRRAEDDLRASKEKAESALLELNAAQQNLID
AERLAALGGLVAGVAHEVNNPIGISLTVASSFSRKTTMFEADLKGDAPLRRSQLDEFVRSSRDAAQQLVANLQRAAELIQ
SFKQVAVDRSHAERRQFNLHEATDQIVASLKPVLKRAPIELAIDVPDGLVIDGYPGAYGQILTNLFLNAANHAFADGRAG
RIAITARPRGDDVEIVFADNGAGMTPDVQRQAFDPFFTTRRNEGGTGLGLHIVYNLVTQQLGGRMMLESRLGQGTTFRII
MPRTATGGPTDADTPIDGNVKWPTRTISSS
>Mature_670_residues
MVGLVRAVPIRWRILSIAALNSLVVLILASMIWSGARVLSSAWDDVRQVRESDKVLALLESETSRLQNLIHRYINQPSPD
LFAEILLLREAVLGTLTNRASTDPMLSGSVAELERVTERFLNGFGDLRALQGKIKDTYENQVQGPARDIAGLYSIIEGAT
GRRDAAIWPPLGRSREAFTAMLVAANSYYLSLSKQAAEDARRNTETIERTVPVMIEFADNDLQKMALQRLKARVAALRDG
LQTLSDQLASRSDLLRNAIDASQASTIGAIDALSVKMRQREQKAQETFDRTLTGISRKVLWIAVIFIGVIMIVGTLIALS
IRLPLQQILAAMHAITSGDYGRRVAGTEARDEVGAMARAVEVFRENAIDKRRAEDDLRASKEKAESALLELNAAQQNLID
AERLAALGGLVAGVAHEVNNPIGISLTVASSFSRKTTMFEADLKGDAPLRRSQLDEFVRSSRDAAQQLVANLQRAAELIQ
SFKQVAVDRSHAERRQFNLHEATDQIVASLKPVLKRAPIELAIDVPDGLVIDGYPGAYGQILTNLFLNAANHAFADGRAG
RIAITARPRGDDVEIVFADNGAGMTPDVQRQAFDPFFTTRRNEGGTGLGLHIVYNLVTQQLGGRMMLESRLGQGTTFRII
MPRTATGGPTDADTPIDGNVKWPTRTISSS

Specific function: Activates virG, by phosphorylating it, in the presence of acetosyringone or hydroxysyringone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=253, Percent_Identity=31.2252964426877, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788549, Length=277, Percent_Identity=26.7148014440433, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081816, Length=354, Percent_Identity=27.4011299435028, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1789149, Length=399, Percent_Identity=25.31328320802, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI145693157, Length=179, Percent_Identity=30.1675977653631, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73246; Mature: 73246

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGLVRAVPIRWRILSIAALNSLVVLILASMIWSGARVLSSAWDDVRQVRESDKVLALLE
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
SETSRLQNLIHRYINQPSPDLFAEILLLREAVLGTLTNRASTDPMLSGSVAELERVTERF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
LNGFGDLRALQGKIKDTYENQVQGPARDIAGLYSIIEGATGRRDAAIWPPLGRSREAFTA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
MLVAANSYYLSLSKQAAEDARRNTETIERTVPVMIEFADNDLQKMALQRLKARVAALRDG
HHHHHCCCEEEECHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHHHHH
LQTLSDQLASRSDLLRNAIDASQASTIGAIDALSVKMRQREQKAQETFDRTLTGISRKVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WIAVIFIGVIMIVGTLIALSIRLPLQQILAAMHAITSGDYGRRVAGTEARDEVGAMARAV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
EVFRENAIDKRRAEDDLRASKEKAESALLELNAAQQNLIDAERLAALGGLVAGVAHEVNN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PIGISLTVASSFSRKTTMFEADLKGDAPLRRSQLDEFVRSSRDAAQQLVANLQRAAELIQ
CCEEEEEECCCCCHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFKQVAVDRSHAERRQFNLHEATDQIVASLKPVLKRAPIELAIDVPDGLVIDGYPGAYGQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCCCHHHH
ILTNLFLNAANHAFADGRAGRIAITARPRGDDVEIVFADNGAGMTPDVQRQAFDPFFTTR
HHHHHHHHHHCHHCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCHHHHHCCCHHHCC
RNEGGTGLGLHIVYNLVTQQLGGRMMLESRLGQGTTFRIIMPRTATGGPTDADTPIDGNV
CCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
KWPTRTISSS
CCCCCCCCCC
>Mature Secondary Structure
MVGLVRAVPIRWRILSIAALNSLVVLILASMIWSGARVLSSAWDDVRQVRESDKVLALLE
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
SETSRLQNLIHRYINQPSPDLFAEILLLREAVLGTLTNRASTDPMLSGSVAELERVTERF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
LNGFGDLRALQGKIKDTYENQVQGPARDIAGLYSIIEGATGRRDAAIWPPLGRSREAFTA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
MLVAANSYYLSLSKQAAEDARRNTETIERTVPVMIEFADNDLQKMALQRLKARVAALRDG
HHHHHCCCEEEECHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHHHHH
LQTLSDQLASRSDLLRNAIDASQASTIGAIDALSVKMRQREQKAQETFDRTLTGISRKVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WIAVIFIGVIMIVGTLIALSIRLPLQQILAAMHAITSGDYGRRVAGTEARDEVGAMARAV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
EVFRENAIDKRRAEDDLRASKEKAESALLELNAAQQNLIDAERLAALGGLVAGVAHEVNN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PIGISLTVASSFSRKTTMFEADLKGDAPLRRSQLDEFVRSSRDAAQQLVANLQRAAELIQ
CCEEEEEECCCCCHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFKQVAVDRSHAERRQFNLHEATDQIVASLKPVLKRAPIELAIDVPDGLVIDGYPGAYGQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCCCHHHH
ILTNLFLNAANHAFADGRAGRIAITARPRGDDVEIVFADNGAGMTPDVQRQAFDPFFTTR
HHHHHHHHHHCHHCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCHHHHHCCCHHHCC
RNEGGTGLGLHIVYNLVTQQLGGRMMLESRLGQGTTFRIIMPRTATGGPTDADTPIDGNV
CCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
KWPTRTISSS
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2796735; 2194232; 11743193; 11743194 [H]