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The map label for this gene is aroK [H]

Identifier: 86751755

GI number: 86751755

Start: 5268586

End: 5269503

Strand: Direct

Name: aroK [H]

Synonym: RPB_4657

Alternate gene names: 86751755

Gene position: 5268586-5269503 (Clockwise)

Preceding gene: 86751750

Following gene: 86751763

Centisome position: 98.82

GC content: 67.43

Gene sequence:

>918_bases
ATGACCCAGTCCGCCGAATCCGACGCCAGCTTCCTGCTGGAGCTCGGGCAGCGTGTCCGCACGTTGCGCGGGTTGCGCGG
GATGTCGCGCAAGGTGCTGGCCAAAGTATCCGGGATCTCCGAACGCTACATCGCCCAGCTCGAAAGCGGCAAGGGCAACG
TCTCGATCATGCTGCTGCGCCGGGTGTCCGACGCGCTGGCCACGCCGCTGGAAGATCTGCTGCCGAGCGGCGATCCGTCG
ATCGACTGGCCGGTGATCCGCGACCTGGTCCGCCGCGCCACGCCGGTGCAGATCGCGCACGCCAAGGACGTGCTGTCCGG
CATGGGACGTCTCGGCGCCGGCGCCAGGCGCGAACACGCGTTTCACGGCATCGCCTTGATCGGCCTGCGCGGCGCCGGCA
AGTCGACGCTCGGCCGGATGTTGGCCGACAAGATCGGCTGGGCCTTCGTCGAGCTGAACAAGGAAATCGAACGTCAAAAC
GGCTTGTCGGTGGCGGAGATCATCGCGCTGTACGGCCAGGAAGGTTTTCGCCGCATGGAGCAGGCGGCGCTGGCGCAATT
GCTGGCGCGCAAGGAACTGATGGTGCTGGCGACCGGCGGCGGCATCGTCTCCGAAGCGATTACTTTCGATCAGATCCTGT
CGTCGTTCTACACCATCTGGCTGAAGGCCGAGCCCGAGGAGCACATGGCGCGGGTGCGCGGCCAGGGCGACCTGCGGCCG
ATGGCCGACGACCGCGCCGCAATGCAGGAGCTGCGCACCATCCTGCAGAGCCGCGAACCGCTCTACGCCCGCGCCTCCGG
CGTGCTCGACACTGCCGGCCTGACGGTCGAGGCGGCCGCGGCGAAGTTGACCGCAATGGTGTCGCCGGTGCTGTGCCGGG
ATGCGTGTGCGTTCGGATTGAAGAACGAGGCGGTGTAA

Upstream 100 bases:

>100_bases
TCATTAGAATTATAATGCATAGGAAGCCACCGGACCGGGTTGCTGTCAATCCTCAGCGGCACTATGATTCCGCTCAACTT
CTCATGAGCGTGCTTCAGAC

Downstream 100 bases:

>100_bases
GACGCTACAAGTAGCAGCGCCGTCATCCTGAGGTGCTCGCCCGCACGGGCGAGCCTCGAAGGATGCGGCGGCCAGCACTG
CGATTGAGGCTCATCCTTCG

Product: anaerobic benzoate catabolism transcriptional regulator

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MTQSAESDASFLLELGQRVRTLRGLRGMSRKVLAKVSGISERYIAQLESGKGNVSIMLLRRVSDALATPLEDLLPSGDPS
IDWPVIRDLVRRATPVQIAHAKDVLSGMGRLGAGARREHAFHGIALIGLRGAGKSTLGRMLADKIGWAFVELNKEIERQN
GLSVAEIIALYGQEGFRRMEQAALAQLLARKELMVLATGGGIVSEAITFDQILSSFYTIWLKAEPEEHMARVRGQGDLRP
MADDRAAMQELRTILQSREPLYARASGVLDTAGLTVEAAAAKLTAMVSPVLCRDACAFGLKNEAV

Sequences:

>Translated_305_residues
MTQSAESDASFLLELGQRVRTLRGLRGMSRKVLAKVSGISERYIAQLESGKGNVSIMLLRRVSDALATPLEDLLPSGDPS
IDWPVIRDLVRRATPVQIAHAKDVLSGMGRLGAGARREHAFHGIALIGLRGAGKSTLGRMLADKIGWAFVELNKEIERQN
GLSVAEIIALYGQEGFRRMEQAALAQLLARKELMVLATGGGIVSEAITFDQILSSFYTIWLKAEPEEHMARVRGQGDLRP
MADDRAAMQELRTILQSREPLYARASGVLDTAGLTVEAAAAKLTAMVSPVLCRDACAFGLKNEAV
>Mature_304_residues
TQSAESDASFLLELGQRVRTLRGLRGMSRKVLAKVSGISERYIAQLESGKGNVSIMLLRRVSDALATPLEDLLPSGDPSI
DWPVIRDLVRRATPVQIAHAKDVLSGMGRLGAGARREHAFHGIALIGLRGAGKSTLGRMLADKIGWAFVELNKEIERQNG
LSVAEIIALYGQEGFRRMEQAALAQLLARKELMVLATGGGIVSEAITFDQILSSFYTIWLKAEPEEHMARVRGQGDLRPM
ADDRAAMQELRTILQSREPLYARASGVLDTAGLTVEAAAAKLTAMVSPVLCRDACAFGLKNEAV

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=147, Percent_Identity=34.0136054421769, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786587, Length=146, Percent_Identity=31.5068493150685, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 33048; Mature: 32917

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50943 HTH_CROC1 ; PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSAESDASFLLELGQRVRTLRGLRGMSRKVLAKVSGISERYIAQLESGKGNVSIMLLR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEHHHH
RVSDALATPLEDLLPSGDPSIDWPVIRDLVRRATPVQIAHAKDVLSGMGRLGAGARREHA
HHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHH
FHGIALIGLRGAGKSTLGRMLADKIGWAFVELNKEIERQNGLSVAEIIALYGQEGFRRME
HCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QAALAQLLARKELMVLATGGGIVSEAITFDQILSSFYTIWLKAEPEEHMARVRGQGDLRP
HHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHCCCCCCCC
MADDRAAMQELRTILQSREPLYARASGVLDTAGLTVEAAAAKLTAMVSPVLCRDACAFGL
CCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
KNEAV
CCCCC
>Mature Secondary Structure 
TQSAESDASFLLELGQRVRTLRGLRGMSRKVLAKVSGISERYIAQLESGKGNVSIMLLR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEHHHH
RVSDALATPLEDLLPSGDPSIDWPVIRDLVRRATPVQIAHAKDVLSGMGRLGAGARREHA
HHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHH
FHGIALIGLRGAGKSTLGRMLADKIGWAFVELNKEIERQNGLSVAEIIALYGQEGFRRME
HCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QAALAQLLARKELMVLATGGGIVSEAITFDQILSSFYTIWLKAEPEEHMARVRGQGDLRP
HHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHCCCCCCCC
MADDRAAMQELRTILQSREPLYARASGVLDTAGLTVEAAAAKLTAMVSPVLCRDACAFGL
CCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
KNEAV
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12835416 [H]