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The map label for this gene is tldD [H]

Identifier: 86751690

GI number: 86751690

Start: 5186014

End: 5187441

Strand: Direct

Name: tldD [H]

Synonym: RPB_4592

Alternate gene names: 86751690

Gene position: 5186014-5187441 (Clockwise)

Preceding gene: 86751687

Following gene: 86751691

Centisome position: 97.27

GC content: 68.21

Gene sequence:

>1428_bases
ATGACCAGCCTCGCCCAGACCTCCCTGCTCGACCGCGCCAATCTCGATCGTGACGACGTCCGCCGCGAGATCGCGCGGGG
GCTGCAGGGGGCCGATGATGGCGAGCTGTTTCTCGAATACAGCCAGACCGAGGCGCTGGCGTTCGACAATGGCCGGCTGA
AGCAGGCGACCTACGACACCGCGCAGGGGTTTGGTTTACGCGCCGTTAAGGACGACGCGGTCGGCTACGCGCATTCCTCC
GACGTGTCGCTGCCGGCGCTGATCCGCGCCGCGGACGCGGTGGCGGCGGTGCGCGGCGACTACAGCGGCGTGCTTTCGGC
GGCGCCGACCCACACCAATGTCCGGCTCTATGGCGACGACAATCCGCTCGACGCGCCGGGCTTCGAGGCCAAGGTCAAGC
TGCTCGCCGAGATCGACGCCTATGTGCGCGACAAGGATTCGCGCGTGCGGCAGGTGTCGGTGTCGGTCGGCGCGACCTGG
CAGGTGGTCGAGATCCTGCGCCCCGACGGCGAGAGCTATCGCGACATCCGCCCGCTGGTGCGGGTCAACGTCTCGGTGGT
CGCCGGCCAGGGTGACCGGCAGGAGAGCGGCTCCAAGGGTTATGGCGGCCGCGAGCCCTATGCGCGCTTCATCGAGACCA
AGGCCTGGCGCGAGGCCGCCGACGGCGCGCTGCGCGAGGCGATGGTCAATCTGGAATCGGTGCCGGCGCCGGCCGGCGAA
ATGGAGGTGGTGCTCGGCCCCGGCTGGCCGGGCGTGATGCTGCACGAGGCGGTCGGCCACGGCCTCGAAGGCGATTTCAA
CCGCAAGAAGACGTCGGCCTTTGCCGGCCTGCTCGGCCAGCAGGTCGCCGCCAAGGGCGTCACCGTGGTCGACGACGGCA
CCATCTCGGCGCGGCGCGGCTCGCTGTCGATCGACGACGAGGGCACGCCGACCAGCCGCACCGTGCTGATCGAGGACGGC
ATCCTCACCGGCTACATGCAGGACCGCCAGAACGCCCGGCTGATGGGCATGAAGCCGACCGGCAACGGCCGCCGGCAGAG
CTACGCCCACGTGCCGATGCCGCGGATGACCAACACCTACATGCTGGCCGGTGGCCACGATCCGGCCGAGATCCTCGCCT
CTGTGAAGAACGGCATCTATGCGGTGAATTTCGGCGGCGGTCAGGTCGACATCACCTCCGGAAAATACGTGTTCCAGTGC
ACCGAGGCCTACAAGATCGAAAACGGCAAGGTCGGCGCGCCGCTCAAGGGCGCGATGCTGATCGGCAACGGACCGACTGA
TTTGCACCGCATTTCCATGATCGGAAACGACCTGCAGCTCGACGACGGCATCGGCACCTGCGGCAAGAACGGCCAGGGCG
TGCCGGTGGGTGTCGGTCAACCGACGCTGCGGATGGATCGGATCACGGTCGGAGGCACCGGCGGATGA

Upstream 100 bases:

>100_bases
ACTTCAGCTCGGCTGATGATGCGCGCTCTTCCCGCCAGCCCCTCGCAGAAGGGCTGCGAAGCGCCTATCTTGAGCGTCGA
ACCGAAGGGAACCCCGCCTC

Downstream 100 bases:

>100_bases
ACGGCAAGGCAGGCATGGTCGCCGGGACGGTGCGGCGCTGGGGCGCCCAACTCGGGCAATTGGCGGCGGTGGTGGCGATC
GTGCTGGCCGGCAAGGCCGC

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MTSLAQTSLLDRANLDRDDVRREIARGLQGADDGELFLEYSQTEALAFDNGRLKQATYDTAQGFGLRAVKDDAVGYAHSS
DVSLPALIRAADAVAAVRGDYSGVLSAAPTHTNVRLYGDDNPLDAPGFEAKVKLLAEIDAYVRDKDSRVRQVSVSVGATW
QVVEILRPDGESYRDIRPLVRVNVSVVAGQGDRQESGSKGYGGREPYARFIETKAWREAADGALREAMVNLESVPAPAGE
MEVVLGPGWPGVMLHEAVGHGLEGDFNRKKTSAFAGLLGQQVAAKGVTVVDDGTISARRGSLSIDDEGTPTSRTVLIEDG
ILTGYMQDRQNARLMGMKPTGNGRRQSYAHVPMPRMTNTYMLAGGHDPAEILASVKNGIYAVNFGGGQVDITSGKYVFQC
TEAYKIENGKVGAPLKGAMLIGNGPTDLHRISMIGNDLQLDDGIGTCGKNGQGVPVGVGQPTLRMDRITVGGTGG

Sequences:

>Translated_475_residues
MTSLAQTSLLDRANLDRDDVRREIARGLQGADDGELFLEYSQTEALAFDNGRLKQATYDTAQGFGLRAVKDDAVGYAHSS
DVSLPALIRAADAVAAVRGDYSGVLSAAPTHTNVRLYGDDNPLDAPGFEAKVKLLAEIDAYVRDKDSRVRQVSVSVGATW
QVVEILRPDGESYRDIRPLVRVNVSVVAGQGDRQESGSKGYGGREPYARFIETKAWREAADGALREAMVNLESVPAPAGE
MEVVLGPGWPGVMLHEAVGHGLEGDFNRKKTSAFAGLLGQQVAAKGVTVVDDGTISARRGSLSIDDEGTPTSRTVLIEDG
ILTGYMQDRQNARLMGMKPTGNGRRQSYAHVPMPRMTNTYMLAGGHDPAEILASVKNGIYAVNFGGGQVDITSGKYVFQC
TEAYKIENGKVGAPLKGAMLIGNGPTDLHRISMIGNDLQLDDGIGTCGKNGQGVPVGVGQPTLRMDRITVGGTGG
>Mature_474_residues
TSLAQTSLLDRANLDRDDVRREIARGLQGADDGELFLEYSQTEALAFDNGRLKQATYDTAQGFGLRAVKDDAVGYAHSSD
VSLPALIRAADAVAAVRGDYSGVLSAAPTHTNVRLYGDDNPLDAPGFEAKVKLLAEIDAYVRDKDSRVRQVSVSVGATWQ
VVEILRPDGESYRDIRPLVRVNVSVVAGQGDRQESGSKGYGGREPYARFIETKAWREAADGALREAMVNLESVPAPAGEM
EVVLGPGWPGVMLHEAVGHGLEGDFNRKKTSAFAGLLGQQVAAKGVTVVDDGTISARRGSLSIDDEGTPTSRTVLIEDGI
LTGYMQDRQNARLMGMKPTGNGRRQSYAHVPMPRMTNTYMLAGGHDPAEILASVKNGIYAVNFGGGQVDITSGKYVFQCT
EAYKIENGKVGAPLKGAMLIGNGPTDLHRISMIGNDLQLDDGIGTCGKNGQGVPVGVGQPTLRMDRITVGGTGG

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=450, Percent_Identity=52, Blast_Score=442, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 50509; Mature: 50378

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLAQTSLLDRANLDRDDVRREIARGLQGADDGELFLEYSQTEALAFDNGRLKQATYDT
CCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEECCCCEEECCCCH
AQGFGLRAVKDDAVGYAHSSDVSLPALIRAADAVAAVRGDYSGVLSAAPTHTNVRLYGDD
HCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCEEEEEECC
NPLDAPGFEAKVKLLAEIDAYVRDKDSRVRQVSVSVGATWQVVEILRPDGESYRDIRPLV
CCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCCHHHHCCEE
RVNVSVVAGQGDRQESGSKGYGGREPYARFIETKAWREAADGALREAMVNLESVPAPAGE
EEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
MEVVLGPGWPGVMLHEAVGHGLEGDFNRKKTSAFAGLLGQQVAAKGVTVVDDGTISARRG
EEEEECCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCEEECCC
SLSIDDEGTPTSRTVLIEDGILTGYMQDRQNARLMGMKPTGNGRRQSYAHVPMPRMTNTY
CEEECCCCCCCCEEEEEECCEEEEEHHCCCCCEEEEECCCCCCCCCCEECCCCCCCCCEE
MLAGGHDPAEILASVKNGIYAVNFGGGQVDITSGKYVFQCTEAYKIENGKVGAPLKGAML
EEECCCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEEEEEEEEECCCCCCCCCCCEEE
IGNGPTDLHRISMIGNDLQLDDGIGTCGKNGQGVPVGVGQPTLRMDRITVGGTGG
ECCCCCCCEEEEECCCCEEECCCCCCCCCCCCEEEECCCCCCEEEEEEEECCCCC
>Mature Secondary Structure 
TSLAQTSLLDRANLDRDDVRREIARGLQGADDGELFLEYSQTEALAFDNGRLKQATYDT
CCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEECCCCEEECCCCH
AQGFGLRAVKDDAVGYAHSSDVSLPALIRAADAVAAVRGDYSGVLSAAPTHTNVRLYGDD
HCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCEEEEEECC
NPLDAPGFEAKVKLLAEIDAYVRDKDSRVRQVSVSVGATWQVVEILRPDGESYRDIRPLV
CCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCCHHHHCCEE
RVNVSVVAGQGDRQESGSKGYGGREPYARFIETKAWREAADGALREAMVNLESVPAPAGE
EEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
MEVVLGPGWPGVMLHEAVGHGLEGDFNRKKTSAFAGLLGQQVAAKGVTVVDDGTISARRG
EEEEECCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCEEECCC
SLSIDDEGTPTSRTVLIEDGILTGYMQDRQNARLMGMKPTGNGRRQSYAHVPMPRMTNTY
CEEECCCCCCCCEEEEEECCEEEEEHHCCCCCEEEEECCCCCCCCCCEECCCCCCCCCEE
MLAGGHDPAEILASVKNGIYAVNFGGGQVDITSGKYVFQCTEAYKIENGKVGAPLKGAML
EEECCCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEEEEEEEEECCCCCCCCCCCEEE
IGNGPTDLHRISMIGNDLQLDDGIGTCGKNGQGVPVGVGQPTLRMDRITVGGTGG
ECCCCCCCEEEEECCCCEEECCCCCCCCCCCCEEEECCCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]