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The map label for this gene is exoN [H]

Identifier: 86751633

GI number: 86751633

Start: 5128382

End: 5129257

Strand: Direct

Name: exoN [H]

Synonym: RPB_4535

Alternate gene names: 86751633

Gene position: 5128382-5129257 (Clockwise)

Preceding gene: 86751632

Following gene: 86751635

Centisome position: 96.19

GC content: 65.3

Gene sequence:

>876_bases
ATGAAAATCCGCAAAGCCGTCTTCCCGGTCGCCGGCCTCGGCACCCGCGTCCTTCCCGCCACCAAGGCGATGCCGAAGGA
GATGCTGACGATCGTCGACAAGCCGCTGATCCAGTACGTCGTCGACGAGGCCAAGGAAGCCGGCATCGAGCATTTCATCT
TCGTCACCGGCCGCAACAAGGGCATGATCGAGGACCATTTCGACCGCCAGTTCGAACTGGACATGACGCTGAAGGGCCGC
AACAAGACCGTGGAAATGGAGCTGTTGGCGCGCGACCAGCCGGAAGCCGGCGCGATGAGTTTCACCCGCCAGCAGGCGCC
GCACGGTCTCGGCCACGCGGTGTGGTGCGCCCGCGACATCGTCGGCAACGAACCGTTCGCGGTGGTGCTGCCGGACGAGC
TGGTGCTGAACTCGCCGGGCTGCCTCAAGCAGATGATTCAGGCCGCGGAAAAGCTGGGCGACAAGGCCAACGTCATCGCG
GTCGAGGAAGTGCCGGCCGACATGACCCACCAATACGGCATCTGCGGCGTCGGCAAGCGCGACGGCAAGATCTTCGAGGT
CGACGGCATGGTGGAGAAGCCGACCAAGGGCACCGCGCCGTCCAACCTGTCGATCACCGGCCGCTACATCCTGCAGCCGG
AGATCTTCAAGATCCTCGCCACCCAGGAGCGCGGCGCCGGCGGCGAGATCCAGCTCACCGACGCGATGATCGGGCTGTCG
AAGACGCAGACATTCTACGGCGTCGAATTCGAGGGCGAGCGCCACGATTGCGGCTCGAAGGCCGGCTTCCTGCGCGCCAA
CATCGCCTTCGCGATGCGGCGCGACGATCTGCGCGACGGCCTCGTCGCCGACATGCAGCGCTATCTCGGGACGTGA

Upstream 100 bases:

>100_bases
GAAGGTTGCGGAACTCCACACATCCGCCTTGGTTGCAAGCTGCAACACCCGCCGGCCCGCCGCAGGCTCCCGCCAGCACA
TTTTTGAAAGATCGCGTTCC

Downstream 100 bases:

>100_bases
TCGCGCCGGTCAGGCGACCAGCGTGAGGTCGCTGCGGTTCGCCGCGACCACGGAGCGGTTTCGGCCGAGATCCTTGGCCG
CGTAGAGCGCCTTGTCGGCG

Product: UTP-glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MKIRKAVFPVAGLGTRVLPATKAMPKEMLTIVDKPLIQYVVDEAKEAGIEHFIFVTGRNKGMIEDHFDRQFELDMTLKGR
NKTVEMELLARDQPEAGAMSFTRQQAPHGLGHAVWCARDIVGNEPFAVVLPDELVLNSPGCLKQMIQAAEKLGDKANVIA
VEEVPADMTHQYGICGVGKRDGKIFEVDGMVEKPTKGTAPSNLSITGRYILQPEIFKILATQERGAGGEIQLTDAMIGLS
KTQTFYGVEFEGERHDCGSKAGFLRANIAFAMRRDDLRDGLVADMQRYLGT

Sequences:

>Translated_291_residues
MKIRKAVFPVAGLGTRVLPATKAMPKEMLTIVDKPLIQYVVDEAKEAGIEHFIFVTGRNKGMIEDHFDRQFELDMTLKGR
NKTVEMELLARDQPEAGAMSFTRQQAPHGLGHAVWCARDIVGNEPFAVVLPDELVLNSPGCLKQMIQAAEKLGDKANVIA
VEEVPADMTHQYGICGVGKRDGKIFEVDGMVEKPTKGTAPSNLSITGRYILQPEIFKILATQERGAGGEIQLTDAMIGLS
KTQTFYGVEFEGERHDCGSKAGFLRANIAFAMRRDDLRDGLVADMQRYLGT
>Mature_291_residues
MKIRKAVFPVAGLGTRVLPATKAMPKEMLTIVDKPLIQYVVDEAKEAGIEHFIFVTGRNKGMIEDHFDRQFELDMTLKGR
NKTVEMELLARDQPEAGAMSFTRQQAPHGLGHAVWCARDIVGNEPFAVVLPDELVLNSPGCLKQMIQAAEKLGDKANVIA
VEEVPADMTHQYGICGVGKRDGKIFEVDGMVEKPTKGTAPSNLSITGRYILQPEIFKILATQERGAGGEIQLTDAMIGLS
KTQTFYGVEFEGERHDCGSKAGFLRANIAFAMRRDDLRDGLVADMQRYLGT

Specific function: May Play A Role In Stationary Phase Survival. [C]

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=298, Percent_Identity=43.9597315436242, Blast_Score=220, Evalue=8e-59,
Organism=Escherichia coli, GI1788355, Length=288, Percent_Identity=39.5833333333333, Blast_Score=191, Evalue=3e-50,
Organism=Escherichia coli, GI1788351, Length=235, Percent_Identity=25.1063829787234, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 32039; Mature: 32039

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRKAVFPVAGLGTRVLPATKAMPKEMLTIVDKPLIQYVVDEAKEAGIEHFIFVTGRNK
CCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCC
GMIEDHFDRQFELDMTLKGRNKTVEMELLARDQPEAGAMSFTRQQAPHGLGHAVWCARDI
CCCHHCCCCEEEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHH
VGNEPFAVVLPDELVLNSPGCLKQMIQAAEKLGDKANVIAVEEVPADMTHQYGICGVGKR
CCCCCEEEECCHHHEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHCCCEECCCCC
DGKIFEVDGMVEKPTKGTAPSNLSITGRYILQPEIFKILATQERGAGGEIQLTDAMIGLS
CCEEEEECCCEECCCCCCCCCCEEEEEEEEECHHHHHHEECCCCCCCCEEEEEHHEECCC
KTQTFYGVEFEGERHDCGSKAGFLRANIAFAMRRDDLRDGLVADMQRYLGT
CCCEEEEEEECCCCCCCCCCCCEEEEHEEEEEEHHHHHCHHHHHHHHHHCC
>Mature Secondary Structure
MKIRKAVFPVAGLGTRVLPATKAMPKEMLTIVDKPLIQYVVDEAKEAGIEHFIFVTGRNK
CCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCC
GMIEDHFDRQFELDMTLKGRNKTVEMELLARDQPEAGAMSFTRQQAPHGLGHAVWCARDI
CCCHHCCCCEEEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHH
VGNEPFAVVLPDELVLNSPGCLKQMIQAAEKLGDKANVIAVEEVPADMTHQYGICGVGKR
CCCCCEEEECCHHHEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHCCCEECCCCC
DGKIFEVDGMVEKPTKGTAPSNLSITGRYILQPEIFKILATQERGAGGEIQLTDAMIGLS
CCEEEEECCCEECCCCCCCCCCEEEEEEEEECHHHHHHEECCCCCCCCEEEEEHHEECCC
KTQTFYGVEFEGERHDCGSKAGFLRANIAFAMRRDDLRDGLVADMQRYLGT
CCCEEEEEEECCCCCCCCCCCCEEEEHEEEEEEHHHHHCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8226645; 8226646; 8246891; 11481431 [H]