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The map label for this gene is qorA [H]

Identifier: 86751592

GI number: 86751592

Start: 5081241

End: 5082239

Strand: Direct

Name: qorA [H]

Synonym: RPB_4494

Alternate gene names: 86751592

Gene position: 5081241-5082239 (Clockwise)

Preceding gene: 86751589

Following gene: 86751593

Centisome position: 95.3

GC content: 67.77

Gene sequence:

>999_bases
ATGGAACCGGTCCCTTCGCAAATGACCGTGATCGGGATCAGCAAGCCCGGCGGACCCGAGGTGCTGCTGCCGGAAACGCG
CGCCGTGCCCACGCCCGGCCCCGGTGAAATCCTGGTCAAGGTCGCGGCGGCCGGGGTCAACCGTCCCGATGTGGCACAGC
GCTCCGGCAGCTATCCGCCGCCGCCCGGCGCCAGCGACCTGCCCGGCCTGGAGATCGCCGGCGAGGTGGTGGCGATCGGC
GACGGCGCGACCCGGCACAAGCTCGGCGACAAGGTGATGTCGCTGGTCGCCGGCGGCGGCTATGCCGAATATTGCATCGC
GCAGGATGCCCAGGCGATGACGGTGCCGGCCGGCTTCTCGATGATCGAGGCCGGCGCCACGCCGGAGACGCTGATGACGG
TGTGGCACAACGTGTTCGAGCGCGGCGCGCTGCAGCCCGGCGAAACCCTGCTGGTGCATGGCGGCTCGTCCGGCATCGGC
ACGATGGCGATCCAGCTCGCGGTCGCATTTGGCGCCAAGGTGATCGCCACCGTCGGCGCGCCCGACAAGGCCGAGGCCTG
CCTGAAACTCGGCGCCACCCGGGCGATCAACTACAAGACCGAGGATTTCGTCGCAGCCGTCAAGGAAACGACCAGCGGCA
AGGGCGCCGACGTGATCCTCGACATGGTCGGCGGCGACTACATCGAGCGCAATTACGATGCCGCCGCAATGGACGGCCGG
ATCGTCCAGATTGCGTTCCTCGGCGGCGCCAAGACCACGGTGAATTTCACCAAGCTGATGATCAAGCGGCTGCACCACAC
CGGTTCGACGCTGCGGCCGCGCAGCAATGCCGACAAGGCCGCGATGGTCGCCGCGATCGAGACCAGGGTGATGCCGCTGC
TCGCCGAAGGCCGGATCAAGCCGCTGATCGACGGCACCTTCGCGTTGCAAGACGCCGCCGCCGCCCACCGGCGGATGGAG
ACCAGCCAACATATTGGCAAAATTGTGTTGACGGTCTGA

Upstream 100 bases:

>100_bases
CGCCGTTCGTGATCCGGTCCGGTTGCCAGCCGCGCCGCGGCTGTCTAATCAGGCTGTCTCATCAGATGGCACCCGCCACC
CCGCCAGCCAAGGACAAATC

Downstream 100 bases:

>100_bases
ATCGGTCCCCGGTTGTTACGCCTATGTTTTCTCCGGGTTTCATGTCATTTATCCGTCGTCGGACACGCGCGGGGGCCGCG
CTTCCAGACCGGTGTGAACG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MEPVPSQMTVIGISKPGGPEVLLPETRAVPTPGPGEILVKVAAAGVNRPDVAQRSGSYPPPPGASDLPGLEIAGEVVAIG
DGATRHKLGDKVMSLVAGGGYAEYCIAQDAQAMTVPAGFSMIEAGATPETLMTVWHNVFERGALQPGETLLVHGGSSGIG
TMAIQLAVAFGAKVIATVGAPDKAEACLKLGATRAINYKTEDFVAAVKETTSGKGADVILDMVGGDYIERNYDAAAMDGR
IVQIAFLGGAKTTVNFTKLMIKRLHHTGSTLRPRSNADKAAMVAAIETRVMPLLAEGRIKPLIDGTFALQDAAAAHRRME
TSQHIGKIVLTV

Sequences:

>Translated_332_residues
MEPVPSQMTVIGISKPGGPEVLLPETRAVPTPGPGEILVKVAAAGVNRPDVAQRSGSYPPPPGASDLPGLEIAGEVVAIG
DGATRHKLGDKVMSLVAGGGYAEYCIAQDAQAMTVPAGFSMIEAGATPETLMTVWHNVFERGALQPGETLLVHGGSSGIG
TMAIQLAVAFGAKVIATVGAPDKAEACLKLGATRAINYKTEDFVAAVKETTSGKGADVILDMVGGDYIERNYDAAAMDGR
IVQIAFLGGAKTTVNFTKLMIKRLHHTGSTLRPRSNADKAAMVAAIETRVMPLLAEGRIKPLIDGTFALQDAAAAHRRME
TSQHIGKIVLTV
>Mature_332_residues
MEPVPSQMTVIGISKPGGPEVLLPETRAVPTPGPGEILVKVAAAGVNRPDVAQRSGSYPPPPGASDLPGLEIAGEVVAIG
DGATRHKLGDKVMSLVAGGGYAEYCIAQDAQAMTVPAGFSMIEAGATPETLMTVWHNVFERGALQPGETLLVHGGSSGIG
TMAIQLAVAFGAKVIATVGAPDKAEACLKLGATRAINYKTEDFVAAVKETTSGKGADVILDMVGGDYIERNYDAAAMDGR
IVQIAFLGGAKTTVNFTKLMIKRLHHTGSTLRPRSNADKAAMVAAIETRVMPLLAEGRIKPLIDGTFALQDAAAAHRRME
TSQHIGKIVLTV

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=332, Percent_Identity=40.9638554216867, Blast_Score=246, Evalue=2e-65,
Organism=Homo sapiens, GI22538444, Length=332, Percent_Identity=40.9638554216867, Blast_Score=246, Evalue=2e-65,
Organism=Homo sapiens, GI194239674, Length=326, Percent_Identity=30.0613496932515, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI13236495, Length=326, Percent_Identity=30.0613496932515, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=28.6173633440514, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI24308257, Length=344, Percent_Identity=26.1627906976744, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI194239676, Length=203, Percent_Identity=34.4827586206897, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI28557745, Length=334, Percent_Identity=32.0359281437126, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI41872631, Length=319, Percent_Identity=28.5266457680251, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI47519420, Length=378, Percent_Identity=27.5132275132275, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI197927207, Length=197, Percent_Identity=25.3807106598985, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=36.3914373088685, Blast_Score=148, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17507255, Length=318, Percent_Identity=26.1006289308176, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI212642053, Length=313, Percent_Identity=25.5591054313099, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71987554, Length=180, Percent_Identity=30.5555555555556, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=336, Percent_Identity=28.2738095238095, Blast_Score=99, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6323961, Length=331, Percent_Identity=25.0755287009063, Blast_Score=89, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6319621, Length=331, Percent_Identity=25.6797583081571, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324486, Length=337, Percent_Identity=23.7388724035608, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24581345, Length=301, Percent_Identity=28.9036544850498, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI19920632, Length=301, Percent_Identity=28.2392026578073, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI221330659, Length=301, Percent_Identity=28.2392026578073, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI45550423, Length=202, Percent_Identity=28.7128712871287, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34441; Mature: 34441

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPVPSQMTVIGISKPGGPEVLLPETRAVPTPGPGEILVKVAAAGVNRPDVAQRSGSYPP
CCCCCCCEEEEEECCCCCCCEECCCCCCCCCCCCHHEEEEEECCCCCCCCHHHHCCCCCC
PPGASDLPGLEIAGEVVAIGDGATRHKLGDKVMSLVAGGGYAEYCIAQDAQAMTVPAGFS
CCCCCCCCCCEECCCEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEECCCCH
MIEAGATPETLMTVWHNVFERGALQPGETLLVHGGSSGIGTMAIQLAVAFGAKVIATVGA
HHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCEEEEECCC
PDKAEACLKLGATRAINYKTEDFVAAVKETTSGKGADVILDMVGGDYIERNYDAAAMDGR
CHHHHHHHHHCCCEEECCCHHHHHHHHHHCCCCCCCEEEEEECCCCHHHCCCCCCCCCCE
IVQIAFLGGAKTTVNFTKLMIKRLHHTGSTLRPRSNADKAAMVAAIETRVMPLLAEGRIK
EEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
PLIDGTFALQDAAAAHRRMETSQHIGKIVLTV
EEECCHHHHHHHHHHHHHHHHHHHHCEEEEEC
>Mature Secondary Structure
MEPVPSQMTVIGISKPGGPEVLLPETRAVPTPGPGEILVKVAAAGVNRPDVAQRSGSYPP
CCCCCCCEEEEEECCCCCCCEECCCCCCCCCCCCHHEEEEEECCCCCCCCHHHHCCCCCC
PPGASDLPGLEIAGEVVAIGDGATRHKLGDKVMSLVAGGGYAEYCIAQDAQAMTVPAGFS
CCCCCCCCCCEECCCEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEECCCCH
MIEAGATPETLMTVWHNVFERGALQPGETLLVHGGSSGIGTMAIQLAVAFGAKVIATVGA
HHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCEEEEECCC
PDKAEACLKLGATRAINYKTEDFVAAVKETTSGKGADVILDMVGGDYIERNYDAAAMDGR
CHHHHHHHHHCCCEEECCCHHHHHHHHHHCCCCCCCEEEEEECCCCHHHCCCCCCCCCCE
IVQIAFLGGAKTTVNFTKLMIKRLHHTGSTLRPRSNADKAAMVAAIETRVMPLLAEGRIK
EEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
PLIDGTFALQDAAAAHRRMETSQHIGKIVLTV
EEECCHHHHHHHHHHHHHHHHHHHHCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]