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The map label for this gene is nreB [H]

Identifier: 86751551

GI number: 86751551

Start: 5039903

End: 5041033

Strand: Direct

Name: nreB [H]

Synonym: RPB_4453

Alternate gene names: 86751551

Gene position: 5039903-5041033 (Clockwise)

Preceding gene: 86751550

Following gene: 86751552

Centisome position: 94.53

GC content: 63.75

Gene sequence:

>1131_bases
ATGAGTAGGCTCGCGACCAGGATTCTGCTGGTCGACGACGCGCAGATTGAATGTCTCGCTTTCGAGCGCCAGTTACACAA
GATTCCCTTCCACCGCCTGCAACTGGATTGGGTCTCGACCTATGCCGATGCGCTCGTGGCGTTCGATCGCGACCAGCACG
ATTTGTATTTCGTCGATTTCCGGCTCGGTCCGGACAACGGCCTCGATCTCGTGCGTCGTGCACGAGTGAACGGAATGACG
AAGCCGATCATCGTGTTGACCGGCCACGGCAGCGCGGCGGTCGACAAGGCGGCGACCGACGCTGGCGCCAACGATTATCT
GGTGAAGGGGGAGTTCGACGCGGTGCTGCTCGAGCGGTCGATTCGTTATGCCTCGCGCAACGCCGACGCGCTTGCGGAGG
TGGGACGCCGCCTGGTCGAAAGCAGGGCGACCGCCCGCGAACTAATGGAGCAGACCAAGCGGCGCGCCGCCGCCGAGGCG
GATGTTCTCCAGGTGCTCAGACAGACGATGACGGACCAGGAGGCCGAGCGTCAGCGGATTGCCCGGGAAATGCACGACAA
TCTCGGCCAGTCGGTAACGCTGGTTCAGCTCGGCCTCGACTCGATCGCACGCAGCGCGTCGGCGCAGAGCGACATCGCGA
GCAAGGCCGCGTCGTTGAAACGCATCACGCACGATATGAGTAGGAGCCTGCATCGGATCGCCTGGGAGGTCCGCCCGACG
GCGCTCGATGCACTCGGCCTGGAGGACGCGATCGGCCAGCTCGTCGCCGAGTGGGAGCCGCATTGCAGCCTGTGCTTCGA
TCTTCACTTCGGGCTCGGCGACCGGAGGTTGCCGCCTGATGTCGAAAGCGCCCTGTATCGCGTAATTCAGGAAGGCATCA
CCAACGTGGTGCGCCACGCAAAGGCGACCCGGGTCGGGGTGATCCTGGAGATGCGGGGCAACGAACTGATCTGCATCGTC
GAAGACGATGGCTGCGGTGTGCCCGAGGTCGAGTCGGGCGTCGCTGAAAAAACGTCGCGTCGACTGGGCCTGCTGGGTAT
GCGCGAGCGGCTGGCTCTCGTCAATGGAACGGTCGAACTCGAATCTCATCCAGAAAAGGGCACGGCGGTGTTCGCGCGCG
TGCCGCTCTAG

Upstream 100 bases:

>100_bases
GTCAAGCCGGCCAGTATCCCCGACTACGTCTCCGCGATCGAATCGCTCTGGCAATTCTGGATGAAGACTGCGTCTCTGCC
GATGACGGAGAGGTTCGGCC

Downstream 100 bases:

>100_bases
GTGAACATGCTCAAGCAAGACCTTGTGCCGCAATTCCTGACACCGGAACCCCGCCGACCGAGTCGTCAGGGGCTGACCCG
GATGTGCCTGCTCCTGCACC

Product: response regulator receiver sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MSRLATRILLVDDAQIECLAFERQLHKIPFHRLQLDWVSTYADALVAFDRDQHDLYFVDFRLGPDNGLDLVRRARVNGMT
KPIIVLTGHGSAAVDKAATDAGANDYLVKGEFDAVLLERSIRYASRNADALAEVGRRLVESRATARELMEQTKRRAAAEA
DVLQVLRQTMTDQEAERQRIAREMHDNLGQSVTLVQLGLDSIARSASAQSDIASKAASLKRITHDMSRSLHRIAWEVRPT
ALDALGLEDAIGQLVAEWEPHCSLCFDLHFGLGDRRLPPDVESALYRVIQEGITNVVRHAKATRVGVILEMRGNELICIV
EDDGCGVPEVESGVAEKTSRRLGLLGMRERLALVNGTVELESHPEKGTAVFARVPL

Sequences:

>Translated_376_residues
MSRLATRILLVDDAQIECLAFERQLHKIPFHRLQLDWVSTYADALVAFDRDQHDLYFVDFRLGPDNGLDLVRRARVNGMT
KPIIVLTGHGSAAVDKAATDAGANDYLVKGEFDAVLLERSIRYASRNADALAEVGRRLVESRATARELMEQTKRRAAAEA
DVLQVLRQTMTDQEAERQRIAREMHDNLGQSVTLVQLGLDSIARSASAQSDIASKAASLKRITHDMSRSLHRIAWEVRPT
ALDALGLEDAIGQLVAEWEPHCSLCFDLHFGLGDRRLPPDVESALYRVIQEGITNVVRHAKATRVGVILEMRGNELICIV
EDDGCGVPEVESGVAEKTSRRLGLLGMRERLALVNGTVELESHPEKGTAVFARVPL
>Mature_375_residues
SRLATRILLVDDAQIECLAFERQLHKIPFHRLQLDWVSTYADALVAFDRDQHDLYFVDFRLGPDNGLDLVRRARVNGMTK
PIIVLTGHGSAAVDKAATDAGANDYLVKGEFDAVLLERSIRYASRNADALAEVGRRLVESRATARELMEQTKRRAAAEAD
VLQVLRQTMTDQEAERQRIAREMHDNLGQSVTLVQLGLDSIARSASAQSDIASKAASLKRITHDMSRSLHRIAWEVRPTA
LDALGLEDAIGQLVAEWEPHCSLCFDLHFGLGDRRLPPDVESALYRVIQEGITNVVRHAKATRVGVILEMRGNELICIVE
DDGCGVPEVESGVAEKTSRRLGLLGMRERLALVNGTVELESHPEKGTAVFARVPL

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4564

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=231, Percent_Identity=29.004329004329, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787474, Length=195, Percent_Identity=25.1282051282051, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 41669; Mature: 41538

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLATRILLVDDAQIECLAFERQLHKIPFHRLQLDWVSTYADALVAFDRDQHDLYFVDF
CCCHHEEEEEEECCCHHHHHHHHHHHHCCHHHEEHHHHHHHHHHHHHCCCCCCCEEEEEE
RLGPDNGLDLVRRARVNGMTKPIIVLTGHGSAAVDKAATDAGANDYLVKGEFDAVLLERS
EECCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHCCCCCCCEEEECCHHHHHHHHH
IRYASRNADALAEVGRRLVESRATARELMEQTKRRAAAEADVLQVLRQTMTDQEAERQRI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AREMHDNLGQSVTLVQLGLDSIARSASAQSDIASKAASLKRITHDMSRSLHRIAWEVRPT
HHHHHHHHCCEEEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ALDALGLEDAIGQLVAEWEPHCSLCFDLHFGLGDRRLPPDVESALYRVIQEGITNVVRHA
HHHHCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KATRVGVILEMRGNELICIVEDDGCGVPEVESGVAEKTSRRLGLLGMRERLALVNGTVEL
HHHHEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
ESHPEKGTAVFARVPL
CCCCCCCCEEEEECCC
>Mature Secondary Structure 
SRLATRILLVDDAQIECLAFERQLHKIPFHRLQLDWVSTYADALVAFDRDQHDLYFVDF
CCHHEEEEEEECCCHHHHHHHHHHHHCCHHHEEHHHHHHHHHHHHHCCCCCCCEEEEEE
RLGPDNGLDLVRRARVNGMTKPIIVLTGHGSAAVDKAATDAGANDYLVKGEFDAVLLERS
EECCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHCCCCCCCEEEECCHHHHHHHHH
IRYASRNADALAEVGRRLVESRATARELMEQTKRRAAAEADVLQVLRQTMTDQEAERQRI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AREMHDNLGQSVTLVQLGLDSIARSASAQSDIASKAASLKRITHDMSRSLHRIAWEVRPT
HHHHHHHHCCEEEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ALDALGLEDAIGQLVAEWEPHCSLCFDLHFGLGDRRLPPDVESALYRVIQEGITNVVRHA
HHHHCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KATRVGVILEMRGNELICIVEDDGCGVPEVESGVAEKTSRRLGLLGMRERLALVNGTVEL
HHHHEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
ESHPEKGTAVFARVPL
CCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]