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The map label for this gene is betA [C]

Identifier: 86751484

GI number: 86751484

Start: 4963887

End: 4965527

Strand: Reverse

Name: betA [C]

Synonym: RPB_4382

Alternate gene names: 86751484

Gene position: 4965527-4963887 (Counterclockwise)

Preceding gene: 86751485

Following gene: 86751483

Centisome position: 93.13

GC content: 69.71

Gene sequence:

>1641_bases
ATGACACAGGACACGCAGGACATCGATCACGCCCGGGCCGTGGCGGAGAACCAGACTCGTCTGCGCGCGCGATTGGCCGA
CGGCTTCGATTTCATCGTGTGCGGCGCCGGCTCGGCGGGCTGCGTGGTCGCGGCGCGTCTGGCCGAGAAGCCCGACGTGC
GGGTGCTGCTGCTCGAAGCCGGCGACGGCGAGATGTCGCCCAGGCTCGTGGAGCCGGCGATGTGGCCGATGAATCTCGGC
ACCGAGCGCGACTGGGCGTTCGAATCGCAGCCGACGCCGACCCTGAACGGGCGGCGCCTTCCGCTCAACATGGGCAAGGG
GCTCGGCGGCGGCTCGAGTATCAACGTCATGGTCTGGGCGCGCGGTCACCGCGCGGATTGGGACTACTTCGCCGCCGAGG
CGGGCGACGGCTGCTGGGGTTACGAATCCGTGCTCGACACCTATCGCCGCATCGAGAGCTGGCAGGGCCATCCCGACCTG
CGTCGGCGCGGGACCGGCGGCCCCGTGCATGTCGAACAGCCGGCCCAGCCGCGGCCGGTCGCCAGCGCGATGGTCGAGGC
CGCGAGCATGCTCGGCCTGCCGCGCTACGCCAGTCCGAACGGCGAGATGATGGAATCCGCCGGCGGCGTGGCATACGCGG
ATCTGCGGATCAAGAACGGGAAGCGGCAGTCGGTCCATCAGTCCTACACCTATCCGCGCATGCACCAGCCGAACCTCACG
GTGCTGACCCACGCGACCGTCGGCCGGCTCGTGCTGGACGGCCACAAGGCGGTCGGGGTGCAGGCCCTGGTCGGCGATCG
GCTGATGACCTTCGATGCGCGCCGCGAGGTCGTGCTGTCGCTCGGTGCGATCAACACGCCGAAGCTGCTGATGCAGTCCG
GCATCGGCCCCGAGGACGAACTGCGCGCCCACGGCATCGAGGTGGTGCAGCATCTGCCGGGCGTCGGCCAAAATCATCAG
GACCATGTCGCCTTCGGCTGCACCTGGGAATATCTGCGGCCGCAGGAGGTCGGCAGCGGCGGGTGCGAGGCGAAACTGTA
CTGGAAGAGCGATGCCCGCCTGGACGCGCCCGACATCCTGCAGTGTCAGCTCGGATTCGCCGTGCCGTCGCCGGCCGAGG
TGGGGATCGCGCCACCGCAGCACGGCTGGACGATGTTCGCCGGGCTGGCTCAGCCGAAGAGCCGCGGGCGTGTGCGGCTG
TCCGGGCCCGATATCGGCGACGCCATGCTGATCGAGCCCAACGCGCTCAGCGAGCCCGAGGACATGGCCGCGGCGCGGGC
GACCATCGAGCTCTGTCGCGAGATCGGCAATCATCCGGCCTTCGGCCGGCAGGTGCAGCGCGAGGTCGTGCCCCGGCTGG
GCGACCGCCTGGCCATGGACCAGTTCATCCGAAACGCGGCGGTGACCTACTGGCATCAATGCGGCACCGCCAAGATGGGC
CGCGACGCGATGGCCGTGGTCGACCGGCGGCTCCGGGTCTACGGGATCGAGAATCTCCGGATCGCGGATGCGTCGATCAT
GCCGCGGATCACCTCCGGCAACACGATGGCGCCCTGCGTCGTGATCGGCGAGCGCGCCGCCGACATGATCTGCGCCGCGC
ATGACGACTCGTTCGACGTCGTCGAGCCCATCGGCGCGTGA

Upstream 100 bases:

>100_bases
AGCGATGCGTCGATCCGATCGCGTCGGACCGTCGGGCGCTGCCGCCTTCCGTTTCACCTCCATCGATGCCGTCGGACCGG
CACCAATCAAGGATCATGTG

Downstream 100 bases:

>100_bases
GCGGCCGACGTCCGACAGGGCGAGCGGGCGGCATGTGGATCGGCCGCCCGCTCGACATCGACGAAGGCCGCGGCAACGAA
TTCACCATGCGGGTCGGGTG

Product: glucose-methanol-choline oxidoreductase

Products: NA

Alternate protein names: SDH [H]

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MTQDTQDIDHARAVAENQTRLRARLADGFDFIVCGAGSAGCVVAARLAEKPDVRVLLLEAGDGEMSPRLVEPAMWPMNLG
TERDWAFESQPTPTLNGRRLPLNMGKGLGGGSSINVMVWARGHRADWDYFAAEAGDGCWGYESVLDTYRRIESWQGHPDL
RRRGTGGPVHVEQPAQPRPVASAMVEAASMLGLPRYASPNGEMMESAGGVAYADLRIKNGKRQSVHQSYTYPRMHQPNLT
VLTHATVGRLVLDGHKAVGVQALVGDRLMTFDARREVVLSLGAINTPKLLMQSGIGPEDELRAHGIEVVQHLPGVGQNHQ
DHVAFGCTWEYLRPQEVGSGGCEAKLYWKSDARLDAPDILQCQLGFAVPSPAEVGIAPPQHGWTMFAGLAQPKSRGRVRL
SGPDIGDAMLIEPNALSEPEDMAAARATIELCREIGNHPAFGRQVQREVVPRLGDRLAMDQFIRNAAVTYWHQCGTAKMG
RDAMAVVDRRLRVYGIENLRIADASIMPRITSGNTMAPCVVIGERAADMICAAHDDSFDVVEPIGA

Sequences:

>Translated_546_residues
MTQDTQDIDHARAVAENQTRLRARLADGFDFIVCGAGSAGCVVAARLAEKPDVRVLLLEAGDGEMSPRLVEPAMWPMNLG
TERDWAFESQPTPTLNGRRLPLNMGKGLGGGSSINVMVWARGHRADWDYFAAEAGDGCWGYESVLDTYRRIESWQGHPDL
RRRGTGGPVHVEQPAQPRPVASAMVEAASMLGLPRYASPNGEMMESAGGVAYADLRIKNGKRQSVHQSYTYPRMHQPNLT
VLTHATVGRLVLDGHKAVGVQALVGDRLMTFDARREVVLSLGAINTPKLLMQSGIGPEDELRAHGIEVVQHLPGVGQNHQ
DHVAFGCTWEYLRPQEVGSGGCEAKLYWKSDARLDAPDILQCQLGFAVPSPAEVGIAPPQHGWTMFAGLAQPKSRGRVRL
SGPDIGDAMLIEPNALSEPEDMAAARATIELCREIGNHPAFGRQVQREVVPRLGDRLAMDQFIRNAAVTYWHQCGTAKMG
RDAMAVVDRRLRVYGIENLRIADASIMPRITSGNTMAPCVVIGERAADMICAAHDDSFDVVEPIGA
>Mature_545_residues
TQDTQDIDHARAVAENQTRLRARLADGFDFIVCGAGSAGCVVAARLAEKPDVRVLLLEAGDGEMSPRLVEPAMWPMNLGT
ERDWAFESQPTPTLNGRRLPLNMGKGLGGGSSINVMVWARGHRADWDYFAAEAGDGCWGYESVLDTYRRIESWQGHPDLR
RRGTGGPVHVEQPAQPRPVASAMVEAASMLGLPRYASPNGEMMESAGGVAYADLRIKNGKRQSVHQSYTYPRMHQPNLTV
LTHATVGRLVLDGHKAVGVQALVGDRLMTFDARREVVLSLGAINTPKLLMQSGIGPEDELRAHGIEVVQHLPGVGQNHQD
HVAFGCTWEYLRPQEVGSGGCEAKLYWKSDARLDAPDILQCQLGFAVPSPAEVGIAPPQHGWTMFAGLAQPKSRGRVRLS
GPDIGDAMLIEPNALSEPEDMAAARATIELCREIGNHPAFGRQVQREVVPRLGDRLAMDQFIRNAAVTYWHQCGTAKMGR
DAMAVVDRRLRVYGIENLRIADASIMPRITSGNTMAPCVVIGERAADMICAAHDDSFDVVEPIGA

Specific function: Can Catalyze The Oxidation Of Choline To Betaine Aldehyde And Betaine Aldehyde To Glycine Betaine At The Same Rate. [C]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=559, Percent_Identity=35.2415026833631, Blast_Score=272, Evalue=5e-73,
Organism=Escherichia coli, GI1786503, Length=537, Percent_Identity=36.8715083798883, Blast_Score=285, Evalue=4e-78,
Organism=Caenorhabditis elegans, GI17532301, Length=548, Percent_Identity=33.029197080292, Blast_Score=262, Evalue=4e-70,
Organism=Drosophila melanogaster, GI24642048, Length=569, Percent_Identity=35.3251318101933, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24642039, Length=571, Percent_Identity=34.1506129597198, Blast_Score=252, Evalue=5e-67,
Organism=Drosophila melanogaster, GI24642055, Length=590, Percent_Identity=33.0508474576271, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI18859995, Length=572, Percent_Identity=33.9160839160839, Blast_Score=244, Evalue=9e-65,
Organism=Drosophila melanogaster, GI24642042, Length=569, Percent_Identity=33.3919156414763, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI45551458, Length=581, Percent_Identity=33.0464716006885, Blast_Score=239, Evalue=5e-63,
Organism=Drosophila melanogaster, GI45549471, Length=581, Percent_Identity=33.0464716006885, Blast_Score=239, Evalue=5e-63,
Organism=Drosophila melanogaster, GI24642035, Length=574, Percent_Identity=33.9721254355401, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24650267, Length=593, Percent_Identity=31.1973018549747, Blast_Score=229, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24642059, Length=569, Percent_Identity=31.9859402460457, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI17137792, Length=561, Percent_Identity=30.6595365418895, Blast_Score=220, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24642037, Length=569, Percent_Identity=32.3374340949033, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24642051, Length=571, Percent_Identity=30.2977232924694, Blast_Score=199, Evalue=3e-51,
Organism=Drosophila melanogaster, GI18859993, Length=567, Percent_Identity=30.1587301587302, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24645930, Length=581, Percent_Identity=29.4320137693632, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24642057, Length=309, Percent_Identity=29.126213592233, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.32 [H]

Molecular weight: Translated: 59381; Mature: 59250

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00623 GMC_OXRED_1 ; PS00624 GMC_OXRED_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDTQDIDHARAVAENQTRLRARLADGFDFIVCGAGSAGCVVAARLAEKPDVRVLLLEA
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCCCCEEEEEEEC
GDGEMSPRLVEPAMWPMNLGTERDWAFESQPTPTLNGRRLPLNMGKGLGGGSSINVMVWA
CCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHCCCCCCCCCCEEEEEEEE
RGHRADWDYFAAEAGDGCWGYESVLDTYRRIESWQGHPDLRRRGTGGPVHVEQPAQPRPV
CCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEECCCCCCCHH
ASAMVEAASMLGLPRYASPNGEMMESAGGVAYADLRIKNGKRQSVHQSYTYPRMHQPNLT
HHHHHHHHHHHCCCCCCCCCCHHHHHCCCEEEEEEEECCCCCHHHHHHCCCCCCCCCCEE
VLTHATVGRLVLDGHKAVGVQALVGDRLMTFDARREVVLSLGAINTPKLLMQSGIGPEDE
EEEECCCCEEEECCCHHHCHHHHHCCCCEEEHHHHHHHHHHCCCCCHHHHHHCCCCCHHH
LRAHGIEVVQHLPGVGQNHQDHVAFGCTWEYLRPQEVGSGGCEAKLYWKSDARLDAPDIL
HHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHCCCCCCEEEEEECCCCCCCCCCEE
QCQLGFAVPSPAEVGIAPPQHGWTMFAGLAQPKSRGRVRLSGPDIGDAMLIEPNALSEPE
EEEECCCCCCCCCCCCCCCCCCCEEEHCCCCCCCCCEEEECCCCCCCEEEECCCCCCCHH
DMAAARATIELCREIGNHPAFGRQVQREVVPRLGDRLAMDQFIRNAAVTYWHQCGTAKMG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RDAMAVVDRRLRVYGIENLRIADASIMPRITSGNTMAPCVVIGERAADMICAAHDDSFDV
CHHHHHHHHHHEEEECCCEEEECHHHCCEECCCCCCCCEEEECCHHHCEEEEECCCCCCC
VEPIGA
CCCCCC
>Mature Secondary Structure 
TQDTQDIDHARAVAENQTRLRARLADGFDFIVCGAGSAGCVVAARLAEKPDVRVLLLEA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCCCCEEEEEEEC
GDGEMSPRLVEPAMWPMNLGTERDWAFESQPTPTLNGRRLPLNMGKGLGGGSSINVMVWA
CCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHCCCCCCCCCCEEEEEEEE
RGHRADWDYFAAEAGDGCWGYESVLDTYRRIESWQGHPDLRRRGTGGPVHVEQPAQPRPV
CCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEECCCCCCCHH
ASAMVEAASMLGLPRYASPNGEMMESAGGVAYADLRIKNGKRQSVHQSYTYPRMHQPNLT
HHHHHHHHHHHCCCCCCCCCCHHHHHCCCEEEEEEEECCCCCHHHHHHCCCCCCCCCCEE
VLTHATVGRLVLDGHKAVGVQALVGDRLMTFDARREVVLSLGAINTPKLLMQSGIGPEDE
EEEECCCCEEEECCCHHHCHHHHHCCCCEEEHHHHHHHHHHCCCCCHHHHHHCCCCCHHH
LRAHGIEVVQHLPGVGQNHQDHVAFGCTWEYLRPQEVGSGGCEAKLYWKSDARLDAPDIL
HHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHCCCCCCEEEEEECCCCCCCCCCEE
QCQLGFAVPSPAEVGIAPPQHGWTMFAGLAQPKSRGRVRLSGPDIGDAMLIEPNALSEPE
EEEECCCCCCCCCCCCCCCCCCCEEEHCCCCCCCCCEEEECCCCCCCEEEECCCCCCCHH
DMAAARATIELCREIGNHPAFGRQVQREVVPRLGDRLAMDQFIRNAAVTYWHQCGTAKMG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RDAMAVVDRRLRVYGIENLRIADASIMPRITSGNTMAPCVVIGERAADMICAAHDDSFDV
CHHHHHHHHHHEEEECCCEEEECHHHCCEECCCCCCCCEEEECCHHHCEEEEECCCCCCC
VEPIGA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9023923 [H]