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The map label for this gene is murA

Identifier: 86751454

GI number: 86751454

Start: 4935765

End: 4937054

Strand: Reverse

Name: murA

Synonym: RPB_4352

Alternate gene names: 86751454

Gene position: 4937054-4935765 (Counterclockwise)

Preceding gene: 86751455

Following gene: 86751453

Centisome position: 92.6

GC content: 66.05

Gene sequence:

>1290_bases
ATGGATCGCATTCGGATTATCGGCGGCAACAAGCTGCATGGCACCATCCCGATCTCCGGTGCCAAGAATGCTGCACTGCC
CTTGATGATCGCCGCGCTGCTCTCCGACGAAACGCTGATCCTGGACAATGTGCCGCGGCTGGCCGACGTCGCGCTGTTGC
AGCGGATCCTCGGGAATCACGGCGTCGACATCATGGCCGCCGGAAAACGCCCCGGGGACCATGAATATCAGGGCCAGACC
CTGCATATTTCCGCAAAGAACATCATCGACACCACCGCGCCCTATGAGCTGGTCTCGAAGATGCGGGCGAGCTTCTGGGT
GATCGCGCCGCTGTTGGCGCGGATGCACGAGGCCAAAGTGTCGCTGCCCGGCGGCTGCGCCATCGGCACCCGCCCGGTCG
ACCTCTTGATCATGGCGCTGGAAAAGCTCGGCGTCGAATTGTCGATCGATGCCGGCTACGTCGTCGCCAAGGCGCCCGGC
GGCCTGAAGGGCGCGACCATCGAGTTTCCCAAGGTCACCGTCAGCGGCACCCATGTCGCGCTGATGGCGGCGACGCTCGC
CAAGGGCACGACGATCATCTCCAATGCCGCCTGCGAGCCGGAAATCACCGACGTCGCCGATTGCCTCAACAAGATGGGCG
CCAGGATCACCGGCGCCGGCACGCCGCGAATCCTGATCGAAGGCGTCGACAAGCTCCACGGCGCGCGCCACACCGTGCTG
CCGGACCGCATCGAGACCGGCACCTATGCGATGGCGGTGGCGATGACCGGTGGCGAGGTGCAGCTGTCCGGCGCCCGGCC
GGAATTGCTGCAGTCGGCGCTCGACGTGCTGACGCAGGCCGGCGCTACCATCACGATCAACAACGACGGCATCAAGGTCG
CGCGCAACGGCGCCGGCATCAGCCCGGTCACGGTCACCACCGCGCCGTTCCCGGGCTTCCCGACCGATCTGCAGGCGCAA
TTGATGGCGCTGATGACGCGCGCCAAGGGCGCGTCGCACATCACCGAGACGATCTTCGAGAACCGCTTCATGCACGTGCA
GGAGCTCGCGCGGTTCGGGGCGAAGATCTCGCTCGACGGCGAGACCGCGACGATCGACGGCGTCACCAAGCTGCGCGGCG
CGCCGGTGATGGCGACTGATCTGCGCGCCTCGGTATCGCTGGTGATCGCAGCGCTCGCCGCCGAAGGCGAGACCATGGTG
AACCGGATCTACCATCTCGACCGCGGCTTCGAGCGGCTCGAGGAAAAACTCTCCGCCTGCGGCGCGACCATCGAGCGCAT
CAGCGGATGA

Upstream 100 bases:

>100_bases
TGACGCAGCGGCAGCTCATGAAATCGCCTTAAATTCCACGCTTTTGCCATAAGCGGCGCTCCTGCCGTATACACGTCCAC
GGCAAACAGCGGGAATCGGC

Downstream 100 bases:

>100_bases
ACGCCGTCGTGGGGGCTGCCTTGGGCCAGTTGAAGCTGCTCGCGCTGGATCCTGACGATCTCGCCGTGATCTCGGCGCAC
GTCCAGGATGCGCGGGTCGA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MDRIRIIGGNKLHGTIPISGAKNAALPLMIAALLSDETLILDNVPRLADVALLQRILGNHGVDIMAAGKRPGDHEYQGQT
LHISAKNIIDTTAPYELVSKMRASFWVIAPLLARMHEAKVSLPGGCAIGTRPVDLLIMALEKLGVELSIDAGYVVAKAPG
GLKGATIEFPKVTVSGTHVALMAATLAKGTTIISNAACEPEITDVADCLNKMGARITGAGTPRILIEGVDKLHGARHTVL
PDRIETGTYAMAVAMTGGEVQLSGARPELLQSALDVLTQAGATITINNDGIKVARNGAGISPVTVTTAPFPGFPTDLQAQ
LMALMTRAKGASHITETIFENRFMHVQELARFGAKISLDGETATIDGVTKLRGAPVMATDLRASVSLVIAALAAEGETMV
NRIYHLDRGFERLEEKLSACGATIERISG

Sequences:

>Translated_429_residues
MDRIRIIGGNKLHGTIPISGAKNAALPLMIAALLSDETLILDNVPRLADVALLQRILGNHGVDIMAAGKRPGDHEYQGQT
LHISAKNIIDTTAPYELVSKMRASFWVIAPLLARMHEAKVSLPGGCAIGTRPVDLLIMALEKLGVELSIDAGYVVAKAPG
GLKGATIEFPKVTVSGTHVALMAATLAKGTTIISNAACEPEITDVADCLNKMGARITGAGTPRILIEGVDKLHGARHTVL
PDRIETGTYAMAVAMTGGEVQLSGARPELLQSALDVLTQAGATITINNDGIKVARNGAGISPVTVTTAPFPGFPTDLQAQ
LMALMTRAKGASHITETIFENRFMHVQELARFGAKISLDGETATIDGVTKLRGAPVMATDLRASVSLVIAALAAEGETMV
NRIYHLDRGFERLEEKLSACGATIERISG
>Mature_429_residues
MDRIRIIGGNKLHGTIPISGAKNAALPLMIAALLSDETLILDNVPRLADVALLQRILGNHGVDIMAAGKRPGDHEYQGQT
LHISAKNIIDTTAPYELVSKMRASFWVIAPLLARMHEAKVSLPGGCAIGTRPVDLLIMALEKLGVELSIDAGYVVAKAPG
GLKGATIEFPKVTVSGTHVALMAATLAKGTTIISNAACEPEITDVADCLNKMGARITGAGTPRILIEGVDKLHGARHTVL
PDRIETGTYAMAVAMTGGEVQLSGARPELLQSALDVLTQAGATITINNDGIKVARNGAGISPVTVTTAPFPGFPTDLQAQ
LMALMTRAKGASHITETIFENRFMHVQELARFGAKISLDGETATIDGVTKLRGAPVMATDLRASVSLVIAALAAEGETMV
NRIYHLDRGFERLEEKLSACGATIERISG

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=429, Percent_Identity=50.5827505827506, Blast_Score=409, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_RHOP2 (Q2IRX1)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_487950.1
- ProteinModelPortal:   Q2IRX1
- SMR:   Q2IRX1
- STRING:   Q2IRX1
- GeneID:   3912166
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_4352
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- BioCyc:   RPAL316058:RPB_4352-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45121; Mature: 45121

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: ACT_SITE 126-126

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIRIIGGNKLHGTIPISGAKNAALPLMIAALLSDETLILDNVPRLADVALLQRILGNH
CCCEEEEECCEEEEEEECCCCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCC
GVDIMAAGKRPGDHEYQGQTLHISAKNIIDTTAPYELVSKMRASFWVIAPLLARMHEAKV
CCEEEECCCCCCCCCCCCCEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
SLPGGCAIGTRPVDLLIMALEKLGVELSIDAGYVVAKAPGGLKGATIEFPKVTVSGTHVA
CCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCEEEEECCCCCCCCEEECCEEEECCCHHH
LMAATLAKGTTIISNAACEPEITDVADCLNKMGARITGAGTPRILIEGVDKLHGARHTVL
HHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHCCEEECCCCCCHHEECHHHHCCCCCCCC
PDRIETGTYAMAVAMTGGEVQLSGARPELLQSALDVLTQAGATITINNDGIKVARNGAGI
CCCCCCCCEEEEEEEECCEEEECCCCHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCC
SPVTVTTAPFPGFPTDLQAQLMALMTRAKGASHITETIFENRFMHVQELARFGAKISLDG
CCEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEECC
ETATIDGVTKLRGAPVMATDLRASVSLVIAALAAEGETMVNRIYHLDRGFERLEEKLSAC
CEEEECCHHHHCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
GATIERISG
HHHHHHCCC
>Mature Secondary Structure
MDRIRIIGGNKLHGTIPISGAKNAALPLMIAALLSDETLILDNVPRLADVALLQRILGNH
CCCEEEEECCEEEEEEECCCCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCC
GVDIMAAGKRPGDHEYQGQTLHISAKNIIDTTAPYELVSKMRASFWVIAPLLARMHEAKV
CCEEEECCCCCCCCCCCCCEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
SLPGGCAIGTRPVDLLIMALEKLGVELSIDAGYVVAKAPGGLKGATIEFPKVTVSGTHVA
CCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCEEEEECCCCCCCCEEECCEEEECCCHHH
LMAATLAKGTTIISNAACEPEITDVADCLNKMGARITGAGTPRILIEGVDKLHGARHTVL
HHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHCCEEECCCCCCHHEECHHHHCCCCCCCC
PDRIETGTYAMAVAMTGGEVQLSGARPELLQSALDVLTQAGATITINNDGIKVARNGAGI
CCCCCCCCEEEEEEEECCEEEECCCCHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCC
SPVTVTTAPFPGFPTDLQAQLMALMTRAKGASHITETIFENRFMHVQELARFGAKISLDG
CCEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEECC
ETATIDGVTKLRGAPVMATDLRASVSLVIAALAAEGETMVNRIYHLDRGFERLEEKLSAC
CEEEECCHHHHCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
GATIERISG
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA