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The map label for this gene is htpX [H]

Identifier: 86751416

GI number: 86751416

Start: 4897715

End: 4898881

Strand: Direct

Name: htpX [H]

Synonym: RPB_4314

Alternate gene names: 86751416

Gene position: 4897715-4898881 (Clockwise)

Preceding gene: 86751415

Following gene: 86751417

Centisome position: 91.86

GC content: 66.41

Gene sequence:

>1167_bases
ATGGCCGCCTACGGTCTCTATACGCACATCGCCGCCAACAGGACCCGCTCGGTCGCGCTGCTGATCGGGCTGTTTCTGCT
GATCTATGTGCTGGTGTTCGCCGGCGCGTTGATCGCCGAGGTGATGATCGATGGCGGGCGCTCGGTCGCGTATTATCTCA
ATGCGGCGGCGGTCGACCTGGTGAAGGCGCTGCCGTTCGCCACGCTCGGCGCGGCGCTGTGGATTGTGATCGCGTATTTC
TTCCATCAGAAGCTGATCGACGCCGTCACCGGCGGCCATGCGGTGACGCGGCAGGAGCAGCCACGGCTGTACAATCTGCT
CGAGAACCTGTGCATCTCGCGCGGCATCCCGATGCCGCAACTGAAGATCATGGACAGCGCGGCGCTCAACGCCTTCGCCA
GCGGCCTCAATCCCAAGCAATACGCCATCACGGTGACGAGCGGCCTTCTGGCCAATCTCGACGACGCTGAAATCGAGGCG
GTGCTCGGCCACGAGCTGACCCACATCCGCAACGGCGACGTGCAGATGATGGTGATCGCCGTGATCATCGCCGGCGTGGT
CGGGTTCTTCGGCGAGATGATGTTCCGGCTGTTTTTCCAGGGCGGCTTCCGCTTCGGCGGCGGCAGCGGCGGGTCGTCGT
CCTCCTCGTCGTCGTCATCGGGAGACCGCAAAAGCGGTGGCGGCGCGATCTTCGTCGTGATCCTGGCGATCGCGCTGATC
GTGCTGGCCTGGCTACTGTCGCAAGTGGTCAAGCTGGCGCTGTCGCGCGCGCGCGAATATCTCGCCGACGCGGGCTCGGT
GGAATTGACCAAGAACCCCGACGCGATGATCTCGGCGCTGCGCAAGATCGAAAACCGCGGCGAACTGGAAGGCGCGACCT
CGGCGGTGATGGAAATGTGCGTCGACAATCCGCGTTCGGGCTTCGCCGATTTGTTCGCCACCCACCCCTCGGTCGAAAAG
CGGGTGGCGGCGCTGGTGCAATTCGCCGGCGGCCGCGATCCCGGCCCGCTGGCGCTGCCGTCGCCGGCCGATGCAACGGA
GCCGTCGGCCGACGATTCAGCCGCGCCTGCGGCGCCGGACGACGCAGCCCCGCTTGGCCCATGGAGCGAGCCTTCGCCAC
CGCGCGCGCGGCGATTCCTTCGCGGGCCGTGGGGCAAGCGGGTGTGA

Upstream 100 bases:

>100_bases
GTGCGGCCCACCCCCACCCGACCGGCCTTACGGCCGGCCACCCTCCCCGCAAGGGGGAGGGAAATTTAGGCCGGCGCTGC
GACACTAACGGATCGCCCTC

Downstream 100 bases:

>100_bases
CACGGGCCAACCGGACGCAATCGCCCCCGATCGGAACGATTTTGTTGAGATTGCCGTCCTGTGCAGCGGCAACAATTGAA
TTATCCCATGTTTCTGCCAT

Product: peptidase M48, Ste24p

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MAAYGLYTHIAANRTRSVALLIGLFLLIYVLVFAGALIAEVMIDGGRSVAYYLNAAAVDLVKALPFATLGAALWIVIAYF
FHQKLIDAVTGGHAVTRQEQPRLYNLLENLCISRGIPMPQLKIMDSAALNAFASGLNPKQYAITVTSGLLANLDDAEIEA
VLGHELTHIRNGDVQMMVIAVIIAGVVGFFGEMMFRLFFQGGFRFGGGSGGSSSSSSSSSGDRKSGGGAIFVVILAIALI
VLAWLLSQVVKLALSRAREYLADAGSVELTKNPDAMISALRKIENRGELEGATSAVMEMCVDNPRSGFADLFATHPSVEK
RVAALVQFAGGRDPGPLALPSPADATEPSADDSAAPAAPDDAAPLGPWSEPSPPRARRFLRGPWGKRV

Sequences:

>Translated_388_residues
MAAYGLYTHIAANRTRSVALLIGLFLLIYVLVFAGALIAEVMIDGGRSVAYYLNAAAVDLVKALPFATLGAALWIVIAYF
FHQKLIDAVTGGHAVTRQEQPRLYNLLENLCISRGIPMPQLKIMDSAALNAFASGLNPKQYAITVTSGLLANLDDAEIEA
VLGHELTHIRNGDVQMMVIAVIIAGVVGFFGEMMFRLFFQGGFRFGGGSGGSSSSSSSSSGDRKSGGGAIFVVILAIALI
VLAWLLSQVVKLALSRAREYLADAGSVELTKNPDAMISALRKIENRGELEGATSAVMEMCVDNPRSGFADLFATHPSVEK
RVAALVQFAGGRDPGPLALPSPADATEPSADDSAAPAAPDDAAPLGPWSEPSPPRARRFLRGPWGKRV
>Mature_387_residues
AAYGLYTHIAANRTRSVALLIGLFLLIYVLVFAGALIAEVMIDGGRSVAYYLNAAAVDLVKALPFATLGAALWIVIAYFF
HQKLIDAVTGGHAVTRQEQPRLYNLLENLCISRGIPMPQLKIMDSAALNAFASGLNPKQYAITVTSGLLANLDDAEIEAV
LGHELTHIRNGDVQMMVIAVIIAGVVGFFGEMMFRLFFQGGFRFGGGSGGSSSSSSSSSGDRKSGGGAIFVVILAIALIV
LAWLLSQVVKLALSRAREYLADAGSVELTKNPDAMISALRKIENRGELEGATSAVMEMCVDNPRSGFADLFATHPSVEKR
VAALVQFAGGRDPGPLALPSPADATEPSADDSAAPAAPDDAAPLGPWSEPSPPRARRFLRGPWGKRV

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=241, Percent_Identity=33.6099585062241, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 41014; Mature: 40883

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAYGLYTHIAANRTRSVALLIGLFLLIYVLVFAGALIAEVMIDGGRSVAYYLNAAAVDL
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHH
VKALPFATLGAALWIVIAYFFHQKLIDAVTGGHAVTRQEQPRLYNLLENLCISRGIPMPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHCCCCCCH
LKIMDSAALNAFASGLNPKQYAITVTSGLLANLDDAEIEAVLGHELTHIRNGDVQMMVIA
HHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
VIIAGVVGFFGEMMFRLFFQGGFRFGGGSGGSSSSSSSSSGDRKSGGGAIFVVILAIALI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
VLAWLLSQVVKLALSRAREYLADAGSVELTKNPDAMISALRKIENRGELEGATSAVMEMC
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VDNPRSGFADLFATHPSVEKRVAALVQFAGGRDPGPLALPSPADATEPSADDSAAPAAPD
HCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DAAPLGPWSEPSPPRARRFLRGPWGKRV
CCCCCCCCCCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AAYGLYTHIAANRTRSVALLIGLFLLIYVLVFAGALIAEVMIDGGRSVAYYLNAAAVDL
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHH
VKALPFATLGAALWIVIAYFFHQKLIDAVTGGHAVTRQEQPRLYNLLENLCISRGIPMPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHCCCCCCH
LKIMDSAALNAFASGLNPKQYAITVTSGLLANLDDAEIEAVLGHELTHIRNGDVQMMVIA
HHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
VIIAGVVGFFGEMMFRLFFQGGFRFGGGSGGSSSSSSSSSGDRKSGGGAIFVVILAIALI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
VLAWLLSQVVKLALSRAREYLADAGSVELTKNPDAMISALRKIENRGELEGATSAVMEMC
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VDNPRSGFADLFATHPSVEKRVAALVQFAGGRDPGPLALPSPADATEPSADDSAAPAAPD
HCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DAAPLGPWSEPSPPRARRFLRGPWGKRV
CCCCCCCCCCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA