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The map label for this gene is mcp4 [H]

Identifier: 86751383

GI number: 86751383

Start: 4862824

End: 4864515

Strand: Direct

Name: mcp4 [H]

Synonym: RPB_4280

Alternate gene names: 86751383

Gene position: 4862824-4864515 (Clockwise)

Preceding gene: 86751378

Following gene: 86751384

Centisome position: 91.21

GC content: 67.79

Gene sequence:

>1692_bases
ATGCTATCGAGACTGCACATGACCATCGGTCGCCGCATCTACCTGCTGATCGGCCTCGGCTTCCTCGGGCTGCTGGGCAC
GACCTTCATGGCGTCGCAGGAGATCGGCGGCGGCCTGAAGCAGCAGAAGCAGATCGAACTCGCCCATCTCACCGACCTCG
CGCTGGCGATCATCAAGGACGAATACGACGCGGCACAGCGCGGCGAGATCAAGGTCGACGAGGCGCAGAAGCGCGCGCAG
GCGCGGCTCTCCAAGCTGCGCTACGGCGGCAAGGAGTACTTCTTCGTCACCGACATGCAGAGCATGATGCTGATGCATCC
GATCGCGACGCAACTGATCGGCAAGGATCAGTCGAACGCCCGCGACCCCAACGGCAAGCCGCTGTTCACCGAAATGGTCG
ACACCGTCCGCCGCAACGGCAGCGGCTTCGTCGACTACGCCTGGCCGAAGCCTGGCTCGGACACGCCCTATCCCAAGCTG
ACCCATGTGGCCGGCTTCGCGCCGTGGGGCTGGATCGTCGGCACCGGCGTGTATATCGACGACCTCGACGCCCAGACCTG
GAGCGCGACGCAGCGCCTGCTGATCGCCGCGACGATCGCGCTGCTGATCATCACCGCGGTGTCGATCCTGGTGGCGCGCG
GCATCACCCGGCCGATCGATGCGATCACCTCGGCGATGAAGACTCTCGCCGGCGGCCGGCTCGACGCCGAGGTGCCCGGC
GTCGGGCGTCGCGACGAGATCGGCGACATGGCCGGCGCGGTCGAAGTGTTCAAGCACAACGCCATCGAGCGCCAGCGGCT
CGAGGCCGAACAGCACGTGACCGAGGAACGCGCCGCCGCGCAGCGCAAGGCCGACACCGTCCGCCTCGCCGACGAGTTCG
AGCGGGCGATCGGCGAGATCGTCGAGACGGTGTCCTCCGCCTCGCACGAACTAGAAGCCTCGGCGACGACGCTGACCACC
ACCGCGGAGCGCTCGCAGCACCTCGCCACGATGGTGTCTTCCGCCTCGGAAGAAGCCTCCACCAACGTCCAGTCGGTGGC
GTCGGCGACCGAGGAGATGAGTTCGTCGGTGAACGAGATCAGCCGCCAGGTGCAGGAATCCGCGCGGATCGCCCATGAGG
CGGTCGAGCAGGCCCGCACCACCAACGGCCGGGTGGAAGAACTCGCCAAGGCGGCGGCGCGGATCGGCGACGTCGTCGAA
CTGATCAACACCATCGCCGGCCAGACCAACCTGCTGGCGCTGAATGCCACGATCGAGGCGGCGCGCGCCGGCGAGGCCGG
TCGCGGCTTCGCCGTGGTCGCCGCGGAAGTCAAGGCGCTGGCCGAGCAGACCGCCAAGGCCACCGGCGAGATCAGCCAGC
AGATCAACGGCATCCAGGTCGCCACCGACCAGTCGGTGACGGCGATCAAGGAGATCGGCGGGACCATCGGGCGGATGTCG
GAAATCTCCTCGACCATCGCCTCGGCGGTGGAAGAACAGGGCGCGGCGACCCAGGAGATTTCGCGCAACGTCCAGCAGGC
GGCGATCGGCACCCAGCAGGTGTCGGTCAACATCACCGACGTGCAGCGCGGCGCCACCGAGACCGGCTCGGCCTCCAGCC
AGGTGCTGTCGGCGGCGAAGTCGCTGTCGCGGGACAGCAACCGCCTCAAGGTCGAGGTGTCGAAGTTCCTCGACAACGTC
CGCGCCGCCTGA

Upstream 100 bases:

>100_bases
TGTCGGGCGTCGCAAGGTCGAACGCGCGATGCCAAGATCGCGCACTGAGCGCAACACCTCCAGCGGGCCGACCCCCGGGG
ACGACAACCGGAGATCACCA

Downstream 100 bases:

>100_bases
GCGGACCACGGCACCCAAGACCGGCCGGCGCCCGCGTGGCGCCGGCTTTCGTTTGAGCTCCGCCTCGGGACCATCCGAGG
CCAGAAGTAAAGCCGGCATT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MLSRLHMTIGRRIYLLIGLGFLGLLGTTFMASQEIGGGLKQQKQIELAHLTDLALAIIKDEYDAAQRGEIKVDEAQKRAQ
ARLSKLRYGGKEYFFVTDMQSMMLMHPIATQLIGKDQSNARDPNGKPLFTEMVDTVRRNGSGFVDYAWPKPGSDTPYPKL
THVAGFAPWGWIVGTGVYIDDLDAQTWSATQRLLIAATIALLIITAVSILVARGITRPIDAITSAMKTLAGGRLDAEVPG
VGRRDEIGDMAGAVEVFKHNAIERQRLEAEQHVTEERAAAQRKADTVRLADEFERAIGEIVETVSSASHELEASATTLTT
TAERSQHLATMVSSASEEASTNVQSVASATEEMSSSVNEISRQVQESARIAHEAVEQARTTNGRVEELAKAAARIGDVVE
LINTIAGQTNLLALNATIEAARAGEAGRGFAVVAAEVKALAEQTAKATGEISQQINGIQVATDQSVTAIKEIGGTIGRMS
EISSTIASAVEEQGAATQEISRNVQQAAIGTQQVSVNITDVQRGATETGSASSQVLSAAKSLSRDSNRLKVEVSKFLDNV
RAA

Sequences:

>Translated_563_residues
MLSRLHMTIGRRIYLLIGLGFLGLLGTTFMASQEIGGGLKQQKQIELAHLTDLALAIIKDEYDAAQRGEIKVDEAQKRAQ
ARLSKLRYGGKEYFFVTDMQSMMLMHPIATQLIGKDQSNARDPNGKPLFTEMVDTVRRNGSGFVDYAWPKPGSDTPYPKL
THVAGFAPWGWIVGTGVYIDDLDAQTWSATQRLLIAATIALLIITAVSILVARGITRPIDAITSAMKTLAGGRLDAEVPG
VGRRDEIGDMAGAVEVFKHNAIERQRLEAEQHVTEERAAAQRKADTVRLADEFERAIGEIVETVSSASHELEASATTLTT
TAERSQHLATMVSSASEEASTNVQSVASATEEMSSSVNEISRQVQESARIAHEAVEQARTTNGRVEELAKAAARIGDVVE
LINTIAGQTNLLALNATIEAARAGEAGRGFAVVAAEVKALAEQTAKATGEISQQINGIQVATDQSVTAIKEIGGTIGRMS
EISSTIASAVEEQGAATQEISRNVQQAAIGTQQVSVNITDVQRGATETGSASSQVLSAAKSLSRDSNRLKVEVSKFLDNV
RAA
>Mature_563_residues
MLSRLHMTIGRRIYLLIGLGFLGLLGTTFMASQEIGGGLKQQKQIELAHLTDLALAIIKDEYDAAQRGEIKVDEAQKRAQ
ARLSKLRYGGKEYFFVTDMQSMMLMHPIATQLIGKDQSNARDPNGKPLFTEMVDTVRRNGSGFVDYAWPKPGSDTPYPKL
THVAGFAPWGWIVGTGVYIDDLDAQTWSATQRLLIAATIALLIITAVSILVARGITRPIDAITSAMKTLAGGRLDAEVPG
VGRRDEIGDMAGAVEVFKHNAIERQRLEAEQHVTEERAAAQRKADTVRLADEFERAIGEIVETVSSASHELEASATTLTT
TAERSQHLATMVSSASEEASTNVQSVASATEEMSSSVNEISRQVQESARIAHEAVEQARTTNGRVEELAKAAARIGDVVE
LINTIAGQTNLLALNATIEAARAGEAGRGFAVVAAEVKALAEQTAKATGEISQQINGIQVATDQSVTAIKEIGGTIGRMS
EISSTIASAVEEQGAATQEISRNVQQAAIGTQQVSVNITDVQRGATETGSASSQVLSAAKSLSRDSNRLKVEVSKFLDNV
RAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=376, Percent_Identity=27.6595744680851, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1788194, Length=196, Percent_Identity=33.6734693877551, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788195, Length=317, Percent_Identity=27.7602523659306, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI2367378, Length=345, Percent_Identity=26.6666666666667, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1789453, Length=341, Percent_Identity=26.6862170087977, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 60194; Mature: 60194

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCCHHEEEHHHHHHHHCCC
>Mature Secondary Structure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HHCCCCCHHEEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]