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The map label for this gene is metX

Identifier: 86751355

GI number: 86751355

Start: 4837799

End: 4839001

Strand: Reverse

Name: metX

Synonym: RPB_4252

Alternate gene names: 86751355

Gene position: 4839001-4837799 (Counterclockwise)

Preceding gene: 86751359

Following gene: 86751354

Centisome position: 90.76

GC content: 66.5

Gene sequence:

>1203_bases
ATGATGAATGTACACCCGGTGAAAGGTCCCGTTGCGACCGGTGGCGAGCGCCCCCACGAGGCCGACCATCCGACGTCGCT
GGTGGCGTCGTTCGGCGCCGACCAGCCGCTGCGGCTCGATTGCGGCGTCGACCTCGCCCCGTTCCAGATCGCCTACCAGA
CCTATGGCACGCTGAACGCCGACAAGAGCAACGCCATTCTGGTCTGCCATGCGCTGACCATGGACCAGCACATCGCCAAT
GTGCATCCGATCACCGGCAAGCCGGGCGGATGGCTGACGCTGGTCGGTCCCGGCAAGCCGATCGACACCGACCGCTATTT
CGTCATCTGCTCCAACGTGATCGGCAGTTGCATGGGCTCGACCGGTCCGGCCTCGACCAATCCGGCCACCGGCAAGGTCT
GGGGCCTCGATTTTCCCGTCATCACCATCCCCGACATGGTCCGCGCCCAGGCGATGCTGGTCGACCGGCTCGGCATCGAC
AAATTGTTCTGCGTCGTCGGCGGCTCGATGGGCGGCATGCAGGTGCTGCAATGGAGCGTCGCCTATCCGGAGCGGGTGTT
CTCGGCGATGCCGATCGCCTGCGCGACGCGGCATTCGGCGCAGAACATCGCCTTCCACGAGCTCGGCCGCCAGGCGGTGA
TGGCCGATCCGGACTGGGCCCATGGCCGCTATGTCGAGACCGGCGCGCATCCGCATCGCGGCCTCGCGGTGGCGCGGATG
GCCGCGCACATCACCTATCTGTCCGACGCCGCCTTGCACCGCAAGTTCGGCCGCAGGATGCAGGACCGCGAACTGCCGAC
GTTCTCGTTCGACGCCGACTTCCAGGTCGAGAGCTATCTGCGCTATCAGGGCTCGTCCTTCGTCGAGCGCTTCGACGCCA
ACTCTTATCTCTATCTGACCCGCGCGATGGATTATTTCGACATCGCCGCCGACCATCACGGCGTGCTGGCGGCGGCGTTC
CGCGGCACCCAGACGCGGTTCTGCGTGGTGTCGTTCACCTCCGACTGGCTGTTCCCGACGCCGGAATCGCGCGCGATCGT
GCATGCGCTCAACGCCGGCGGCGCGCGGGTGTCGTTCGCCGAAGTCGAGACCGACAAAGGCCACGACGCCTTTCTGCTCG
ACGAGCCGGAATTCATCGACATCGCCCGCGCCTTCCTGCACTCGGCTGCGACCGCGCGCGGGCTCGACAAAGCGGGGCGC
TGA

Upstream 100 bases:

>100_bases
TCTGATCCCGGCCGAACCGATGTTCAGGCCGGGTTTTTTATTGGCTCGGTCGCTCTTATCTGAGGTCAGCGGGGATGCCC
TCGCTGAGGCCGTTGGCAGT

Downstream 100 bases:

>100_bases
GATGGCGGTGCAGGAGAGCTTGCCGCTGGAGCCGCCGGCGCGCACCACGCTGCGGGTGCATCGCGCCGATCACCTGCTGG
TCGCCGACATGGTCGAGCCC

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MMNVHPVKGPVATGGERPHEADHPTSLVASFGADQPLRLDCGVDLAPFQIAYQTYGTLNADKSNAILVCHALTMDQHIAN
VHPITGKPGGWLTLVGPGKPIDTDRYFVICSNVIGSCMGSTGPASTNPATGKVWGLDFPVITIPDMVRAQAMLVDRLGID
KLFCVVGGSMGGMQVLQWSVAYPERVFSAMPIACATRHSAQNIAFHELGRQAVMADPDWAHGRYVETGAHPHRGLAVARM
AAHITYLSDAALHRKFGRRMQDRELPTFSFDADFQVESYLRYQGSSFVERFDANSYLYLTRAMDYFDIAADHHGVLAAAF
RGTQTRFCVVSFTSDWLFPTPESRAIVHALNAGGARVSFAEVETDKGHDAFLLDEPEFIDIARAFLHSAATARGLDKAGR

Sequences:

>Translated_400_residues
MMNVHPVKGPVATGGERPHEADHPTSLVASFGADQPLRLDCGVDLAPFQIAYQTYGTLNADKSNAILVCHALTMDQHIAN
VHPITGKPGGWLTLVGPGKPIDTDRYFVICSNVIGSCMGSTGPASTNPATGKVWGLDFPVITIPDMVRAQAMLVDRLGID
KLFCVVGGSMGGMQVLQWSVAYPERVFSAMPIACATRHSAQNIAFHELGRQAVMADPDWAHGRYVETGAHPHRGLAVARM
AAHITYLSDAALHRKFGRRMQDRELPTFSFDADFQVESYLRYQGSSFVERFDANSYLYLTRAMDYFDIAADHHGVLAAAF
RGTQTRFCVVSFTSDWLFPTPESRAIVHALNAGGARVSFAEVETDKGHDAFLLDEPEFIDIARAFLHSAATARGLDKAGR
>Mature_400_residues
MMNVHPVKGPVATGGERPHEADHPTSLVASFGADQPLRLDCGVDLAPFQIAYQTYGTLNADKSNAILVCHALTMDQHIAN
VHPITGKPGGWLTLVGPGKPIDTDRYFVICSNVIGSCMGSTGPASTNPATGKVWGLDFPVITIPDMVRAQAMLVDRLGID
KLFCVVGGSMGGMQVLQWSVAYPERVFSAMPIACATRHSAQNIAFHELGRQAVMADPDWAHGRYVETGAHPHRGLAVARM
AAHITYLSDAALHRKFGRRMQDRELPTFSFDADFQVESYLRYQGSSFVERFDANSYLYLTRAMDYFDIAADHHGVLAAAF
RGTQTRFCVVSFTSDWLFPTPESRAIVHALNAGGARVSFAEVETDKGHDAFLLDEPEFIDIARAFLHSAATARGLDKAGR

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=224, Percent_Identity=39.2857142857143, Blast_Score=163, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_RHOP2 (Q2IS70)

Other databases:

- EMBL:   CP000250
- RefSeq:   YP_487851.1
- STRING:   Q2IS70
- GeneID:   3912065
- GenomeReviews:   CP000250_GR
- KEGG:   rpb:RPB_4252
- eggNOG:   COG2021
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- ProtClustDB:   PRK00175
- BioCyc:   RPAL316058:RPB_4252-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 43581; Mature: 43581

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: ACT_SITE 169-169 ACT_SITE 368-368

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNVHPVKGPVATGGERPHEADHPTSLVASFGADQPLRLDCGVDLAPFQIAYQTYGTLNA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCCCCCCCEEEEECCCCCCC
DKSNAILVCHALTMDQHIANVHPITGKPGGWLTLVGPGKPIDTDRYFVICSNVIGSCMGS
CCCCEEEEEEEECHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEHHHHHHHCCC
TGPASTNPATGKVWGLDFPVITIPDMVRAQAMLVDRLGIDKLFCVVGGSMGGMQVLQWSV
CCCCCCCCCCCEEEECCCCEEECCHHHHHHHHHHHHCCHHEEEEEECCCCCCHHHEEEHH
AYPERVFSAMPIACATRHSAQNIAFHELGRQAVMADPDWAHGRYVETGAHPHRGLAVARM
CCHHHHHHCCCHHHHCCCCCCCHHHHHHCCEEEECCCCCCCCEEEECCCCCCCCHHHHHH
AAHITYLSDAALHRKFGRRMQDRELPTFSFDADFQVESYLRYQGSSFVERFDANSYLYLT
HHHHHHHHHHHHHHHHHCHHHHCCCCEEECCCCCCHHHHHHHCCCHHHHHHCCCCEEEEE
RAMDYFDIAADHHGVLAAAFRGTQTRFCVVSFTSDWLFPTPESRAIVHALNAGGARVSFA
ECCCHHHHCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCCCEEEEE
EVETDKGHDAFLLDEPEFIDIARAFLHSAATARGLDKAGR
EEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHCHHHCCC
>Mature Secondary Structure
MMNVHPVKGPVATGGERPHEADHPTSLVASFGADQPLRLDCGVDLAPFQIAYQTYGTLNA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEECCCCCCCCEEEEECCCCCCC
DKSNAILVCHALTMDQHIANVHPITGKPGGWLTLVGPGKPIDTDRYFVICSNVIGSCMGS
CCCCEEEEEEEECHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEHHHHHHHCCC
TGPASTNPATGKVWGLDFPVITIPDMVRAQAMLVDRLGIDKLFCVVGGSMGGMQVLQWSV
CCCCCCCCCCCEEEECCCCEEECCHHHHHHHHHHHHCCHHEEEEEECCCCCCHHHEEEHH
AYPERVFSAMPIACATRHSAQNIAFHELGRQAVMADPDWAHGRYVETGAHPHRGLAVARM
CCHHHHHHCCCHHHHCCCCCCCHHHHHHCCEEEECCCCCCCCEEEECCCCCCCCHHHHHH
AAHITYLSDAALHRKFGRRMQDRELPTFSFDADFQVESYLRYQGSSFVERFDANSYLYLT
HHHHHHHHHHHHHHHHHCHHHHCCCCEEECCCCCCHHHHHHHCCCHHHHHHCCCCEEEEE
RAMDYFDIAADHHGVLAAAFRGTQTRFCVVSFTSDWLFPTPESRAIVHALNAGGARVSFA
ECCCHHHHCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCCCEEEEE
EVETDKGHDAFLLDEPEFIDIARAFLHSAATARGLDKAGR
EEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA