Click here to switch to the map view.

The map label for this gene is braD [H]

Identifier: 86751313

GI number: 86751313

Start: 4779303

End: 4780322

Strand: Direct

Name: braD [H]

Synonym: RPB_4207

Alternate gene names: 86751313

Gene position: 4779303-4780322 (Clockwise)

Preceding gene: 86751312

Following gene: 86751314

Centisome position: 89.64

GC content: 66.27

Gene sequence:

>1020_bases
ATGACCGATGTCCCCATCCCCGCCCCCTCCGACGCCCTGCCCAAGCCCAAGCGCGATCTCGTACCGGTGCTACTGCCGCT
GATCCTGGCGCTGCTGATGCTGCCGCTGGTCGGCTCGTTCTCATCCTGGGTGACGCTGACGGTCGCGTCGCTCGCGATGG
GGATGATGATCTTCATCATGGCGTCCGGCCTGACGCTGGTGTTCGGGCTGATGGACGTGCTGAATTTCGGCCACGGTGCC
TTCATTGCGGTCGGCGCCTATGTGGCGACGCTGGTGCTGCTGCCGCTCGCCGGGATGTCACAGGCGGATTCGCTGCTGGT
GAATCTGGCGGTGCTGGCGCCGGCGGCGCTGGCCGCAATGGCGGTGTCGGGCGCGCTCGGCCTGGTCGTCGAGCGCGTGC
TGATCCTGCCGGTCTACGGCCAGCACCTGAAGCAGATCCTGATGACCACCGGCGGGCTCATCGTCGCGGAGCAGGCGCTG
TATGCGCTGTGGGGGCCGCAGATCATCCCGCTGCCGCTGCCGACGGCACTGCGCGGCTCGTTCATCATCGGCGACATCGC
GATCGCCAAATATCGCCTGCTGGTGCTGCTGGTCGGGATCGCGGTGTTCGTCGCGATCCAGCTCGTGCTCAACCGTACCA
AGATCGGGCTGCTGATCCGCGCCGGCGTCGAGAATCGCGAGATGGTCGAGGCGCTCGGCTATCACATCAAGCGGCTGTTC
CTCGGCGTGTTCATGGTCGGCTCGGCGCTCGCCGGATTCGGCGGCATCATGTGGGCGCTGTATCGCGAGCAGGTCCACGC
CTCGATGGGCAACGACCTCACCGTGCTGATTTTCATCGTCGTGATCATCGGCGGGCTCGGCTCGGTCGGCGGTTGTTTCA
TCGGCGCGCTGCTGGTGGCGATGGTCGCCAATTACGGCGGCTTCCTGGTGCCGAAGCTGGCGCTGGTCTCCAACATCCTG
CTGATGGTCGCGATCCTGATGTGGCGGCCGCGCGGGCTCTATGCGGTGACGAGCCGATGA

Upstream 100 bases:

>100_bases
CGTCATTGCGAGCCGAAGGCGAAGCAATCCAGCGCAGTGCACGGGGCCCCTGGATTGCTTCGTCGGCTTCGCCTCCTCGC
AATGACGAATCGTGACTGAC

Downstream 100 bases:

>100_bases
GGGTTAGGCGATGATGCTTCTCTCCGGCGATCCGCCGCGCAGCCGGGTGCTGGCGCTGATCCTGATCGCGATCATCGCGA
TGCTGGCGATCACCCCGTTC

Product: inner-membrane translocator

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MTDVPIPAPSDALPKPKRDLVPVLLPLILALLMLPLVGSFSSWVTLTVASLAMGMMIFIMASGLTLVFGLMDVLNFGHGA
FIAVGAYVATLVLLPLAGMSQADSLLVNLAVLAPAALAAMAVSGALGLVVERVLILPVYGQHLKQILMTTGGLIVAEQAL
YALWGPQIIPLPLPTALRGSFIIGDIAIAKYRLLVLLVGIAVFVAIQLVLNRTKIGLLIRAGVENREMVEALGYHIKRLF
LGVFMVGSALAGFGGIMWALYREQVHASMGNDLTVLIFIVVIIGGLGSVGGCFIGALLVAMVANYGGFLVPKLALVSNIL
LMVAILMWRPRGLYAVTSR

Sequences:

>Translated_339_residues
MTDVPIPAPSDALPKPKRDLVPVLLPLILALLMLPLVGSFSSWVTLTVASLAMGMMIFIMASGLTLVFGLMDVLNFGHGA
FIAVGAYVATLVLLPLAGMSQADSLLVNLAVLAPAALAAMAVSGALGLVVERVLILPVYGQHLKQILMTTGGLIVAEQAL
YALWGPQIIPLPLPTALRGSFIIGDIAIAKYRLLVLLVGIAVFVAIQLVLNRTKIGLLIRAGVENREMVEALGYHIKRLF
LGVFMVGSALAGFGGIMWALYREQVHASMGNDLTVLIFIVVIIGGLGSVGGCFIGALLVAMVANYGGFLVPKLALVSNIL
LMVAILMWRPRGLYAVTSR
>Mature_338_residues
TDVPIPAPSDALPKPKRDLVPVLLPLILALLMLPLVGSFSSWVTLTVASLAMGMMIFIMASGLTLVFGLMDVLNFGHGAF
IAVGAYVATLVLLPLAGMSQADSLLVNLAVLAPAALAAMAVSGALGLVVERVLILPVYGQHLKQILMTTGGLIVAEQALY
ALWGPQIIPLPLPTALRGSFIIGDIAIAKYRLLVLLVGIAVFVAIQLVLNRTKIGLLIRAGVENREMVEALGYHIKRLFL
GVFMVGSALAGFGGIMWALYREQVHASMGNDLTVLIFIVVIIGGLGSVGGCFIGALLVAMVANYGGFLVPKLALVSNILL
MVAILMWRPRGLYAVTSR

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 35758; Mature: 35627

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDVPIPAPSDALPKPKRDLVPVLLPLILALLMLPLVGSFSSWVTLTVASLAMGMMIFIM
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ASGLTLVFGLMDVLNFGHGAFIAVGAYVATLVLLPLAGMSQADSLLVNLAVLAPAALAAM
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AVSGALGLVVERVLILPVYGQHLKQILMTTGGLIVAEQALYALWGPQIIPLPLPTALRGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEECCCCCHHHCCC
FIIGDIAIAKYRLLVLLVGIAVFVAIQLVLNRTKIGLLIRAGVENREMVEALGYHIKRLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHH
LGVFMVGSALAGFGGIMWALYREQVHASMGNDLTVLIFIVVIIGGLGSVGGCFIGALLVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
MVANYGGFLVPKLALVSNILLMVAILMWRPRGLYAVTSR
HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
>Mature Secondary Structure 
TDVPIPAPSDALPKPKRDLVPVLLPLILALLMLPLVGSFSSWVTLTVASLAMGMMIFIM
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH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HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043; 2509433 [H]