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The map label for this gene is mngR [H]

Identifier: 86751171

GI number: 86751171

Start: 4634791

End: 4635561

Strand: Direct

Name: mngR [H]

Synonym: RPB_4063

Alternate gene names: 86751171

Gene position: 4634791-4635561 (Clockwise)

Preceding gene: 86751170

Following gene: 86751173

Centisome position: 86.93

GC content: 65.37

Gene sequence:

>771_bases
ATGAGGAAGATCAACGCCAGTTCCGACGCGGATCGTCATGCTCACGGTATGGACCTGAGCATCGACAGCCACGTGCCCAA
ATACGCGCAGATCGCCGACATCTTCCGGCAGCGGATCGCGCGCGGGAGCTGGTCGCGCGGCATGCGGCTGCCGGCCAACG
AGGCGCTGGCCGAAGAATTCGGCGTCTCGCGCGTCACCATCCGGCAGGCGGTCGAGCTGCTCGCGCGCGACGGCATCCTC
GAAGCGCAACAGGGCCGCGGCACCTTCATCACCGGCCAGGTCAAGCAGGACCGCTGGCTGAAGGTCGAGACCTCGCTGTC
CGATCTCGCCGAAGTCTATCAGGACACCTCGCCCGAGATCATCAACATCGCCGAAAGTATCAGCAAGGCTCCCCTGATCG
AGGCCGACGGCAAGGCCGCGGCACGCTACGTCTTCATGCGGCGGGTGCATTCGCGCGGCGGCCAGCCTTATTGCGTGATC
TCGATCTATCTCGACGAGACGATCTTCCGCCGCTCGCCGGCCAAATTCCGCAAGCAGACCGTGATTCCGATCCTGAAAGA
TCTCAAGAACCCGGCGATCGCCAGCGCGCGGCAGACGCTGACCATCGGCACCGCCGACCTCGAAGTCGCGCGGCTGCTGC
GCGTGCCGCTGAACTCGCCGGTCGCCGAAGTGCGCCGCGTCTTCACCGCCGCCGACCGCACCGTGATCTATCTCGGCGAA
GTGACTTACCGCGGCGACTTCGTCCGGATCGACATGGACCTTCGCCCCTGA

Upstream 100 bases:

>100_bases
TGCGCGTGGTCGACGCCTCGGTGATGCCACTGATCACCTCGGCCAATACCAACGCCGCCAGCCTGATGATCGGCGAGAAG
GGCGCCGCCCTGATCGCCTC

Downstream 100 bases:

>100_bases
GCCGAGCCGATCAGCGAAAGAACACTTCCTGATTGCGCCGCTCGAGCTCGGTGGCGAAAGTGCGCAGCACATGCGCCTCG
CTGACGAGGCCGATCGTCAC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: Fatty acyl-responsive regulator; Protein P30 [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MRKINASSDADRHAHGMDLSIDSHVPKYAQIADIFRQRIARGSWSRGMRLPANEALAEEFGVSRVTIRQAVELLARDGIL
EAQQGRGTFITGQVKQDRWLKVETSLSDLAEVYQDTSPEIINIAESISKAPLIEADGKAAARYVFMRRVHSRGGQPYCVI
SIYLDETIFRRSPAKFRKQTVIPILKDLKNPAIASARQTLTIGTADLEVARLLRVPLNSPVAEVRRVFTAADRTVIYLGE
VTYRGDFVRIDMDLRP

Sequences:

>Translated_256_residues
MRKINASSDADRHAHGMDLSIDSHVPKYAQIADIFRQRIARGSWSRGMRLPANEALAEEFGVSRVTIRQAVELLARDGIL
EAQQGRGTFITGQVKQDRWLKVETSLSDLAEVYQDTSPEIINIAESISKAPLIEADGKAAARYVFMRRVHSRGGQPYCVI
SIYLDETIFRRSPAKFRKQTVIPILKDLKNPAIASARQTLTIGTADLEVARLLRVPLNSPVAEVRRVFTAADRTVIYLGE
VTYRGDFVRIDMDLRP
>Mature_256_residues
MRKINASSDADRHAHGMDLSIDSHVPKYAQIADIFRQRIARGSWSRGMRLPANEALAEEFGVSRVTIRQAVELLARDGIL
EAQQGRGTFITGQVKQDRWLKVETSLSDLAEVYQDTSPEIINIAESISKAPLIEADGKAAARYVFMRRVHSRGGQPYCVI
SIYLDETIFRRSPAKFRKQTVIPILKDLKNPAIASARQTLTIGTADLEVARLLRVPLNSPVAEVRRVFTAADRTVIYLGE
VTYRGDFVRIDMDLRP

Specific function: Represses mngA and mngB. Regulates its own expression [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=202, Percent_Identity=28.7128712871287, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI87082252, Length=236, Percent_Identity=23.3050847457627, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790118, Length=202, Percent_Identity=27.7227722772277, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 28705; Mature: 28705

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKINASSDADRHAHGMDLSIDSHVPKYAQIADIFRQRIARGSWSRGMRLPANEALAEEF
CCCCCCCCCCCHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
GVSRVTIRQAVELLARDGILEAQQGRGTFITGQVKQDRWLKVETSLSDLAEVYQDTSPEI
CCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEEECCHHHHHHHHHCCCCHH
INIAESISKAPLIEADGKAAARYVFMRRVHSRGGQPYCVISIYLDETIFRRSPAKFRKQT
HHHHHHHHCCCCEECCCHHHHHHHHHHHHHHCCCCCEEEEEEEECHHHHHCCCHHHHHHH
VIPILKDLKNPAIASARQTLTIGTADLEVARLLRVPLNSPVAEVRRVFTAADRTVIYLGE
HHHHHHHCCCCHHHCCCCEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEEC
VTYRGDFVRIDMDLRP
EEECCCEEEEEECCCC
>Mature Secondary Structure
MRKINASSDADRHAHGMDLSIDSHVPKYAQIADIFRQRIARGSWSRGMRLPANEALAEEF
CCCCCCCCCCCHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
GVSRVTIRQAVELLARDGILEAQQGRGTFITGQVKQDRWLKVETSLSDLAEVYQDTSPEI
CCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEEECCHHHHHHHHHCCCCHH
INIAESISKAPLIEADGKAAARYVFMRRVHSRGGQPYCVISIYLDETIFRRSPAKFRKQT
HHHHHHHHCCCCEECCCHHHHHHHHHHHHHHCCCCCEEEEEEEECHHHHHCCCHHHHHHH
VIPILKDLKNPAIASARQTLTIGTADLEVARLLRVPLNSPVAEVRRVFTAADRTVIYLGE
HHHHHHHCCCCHHHCCCCEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEEC
VTYRGDFVRIDMDLRP
EEECCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548486; 9278503; 9063979; 8905232; 7805834 [H]