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The map label for this gene is ccdA [H]

Identifier: 86750796

GI number: 86750796

Start: 4226202

End: 4226936

Strand: Reverse

Name: ccdA [H]

Synonym: RPB_3686

Alternate gene names: 86750796

Gene position: 4226936-4226202 (Counterclockwise)

Preceding gene: 86750798

Following gene: 86750790

Centisome position: 79.28

GC content: 67.21

Gene sequence:

>735_bases
ATGATCCATGACGTCTCGATCCCCGCGGCGCTGCTCGCCGGCTTGGTCAGCTTCCTGTCGCCCTGCGTGCTCCCGCTGGT
GCCGCCATACCTGATCTATCTGACCGGCGCGACCATCGAGCACGTCGCCGCCGACGAATCCCAGCGCAATTCGAAACGCG
CCGTGATGATCTCGGCGCTGGTCTTCGTGCTCGGCTTCTCGACCGTGTTCGTGGCACTCGGCGCCAGCGCCAGCCTGGTC
GGCGGCCTGATCCGGGCCTGGTCGGCCGAACTCGCGATCGTCGCCGGCATCGTCATCATTCTGATGGGGCTGCATTTCCT
CGGCCTGACGCGGCTCAACATCCTGATGCGCGAGGGCCGGCTGCCGATCCCAAAACCAGTGGGCCTGTGGGGCGCCTATG
TGATGGGGCTCGCCTTCGCGTTCGGCTGGACGCCGTGCATCGGCCCGATCCTCGCCGCGATCCTGTCGGTCGCCGCGGCC
GAAGCCACGGTGGCGAAGGGCGCGGGGCTACTGGCGGTCTATTCCGCGGGCCTCGGCATTCCGTTCCTGCTCGCGGCCTT
GATGGTCGAGCAGTTCTCCGGCCTGTTCGCGCGGATGAAGAAGCACCTCGCCATCGTCGAACGCGTGATGGGCGCGCTGA
TGGTTCTGACCGGCATCGCCTTCCTCACCGGCGCCATCACCGACGTCAGCGTCTGGCTGCTGAATACGTTCCCGGCGCTG
GGGACGATCGGGTGA

Upstream 100 bases:

>100_bases
TAAACACTTCGTCGAGCAACCCTCACGCCGCGATCACAAGCTGCGGAAGCTCGCCGCAGCGGGCCTTGCGCGGCCGACGA
GGGCAGGTGCATGTAGCCGC

Downstream 100 bases:

>100_bases
GGCGGCCGGCGCTGAATTGGTAAGGCGCCGATATTCGTCGAACGCGCATCGCCATCAAAGGACGTCATCCTCCGCGAACG
CGGAGGATCCACTATCCCAG

Product: cytochrome c biogenesis protein, transmembrane region

Products: DsbDoxidized; DsbGreduced [C]

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MIHDVSIPAALLAGLVSFLSPCVLPLVPPYLIYLTGATIEHVAADESQRNSKRAVMISALVFVLGFSTVFVALGASASLV
GGLIRAWSAELAIVAGIVIILMGLHFLGLTRLNILMREGRLPIPKPVGLWGAYVMGLAFAFGWTPCIGPILAAILSVAAA
EATVAKGAGLLAVYSAGLGIPFLLAALMVEQFSGLFARMKKHLAIVERVMGALMVLTGIAFLTGAITDVSVWLLNTFPAL
GTIG

Sequences:

>Translated_244_residues
MIHDVSIPAALLAGLVSFLSPCVLPLVPPYLIYLTGATIEHVAADESQRNSKRAVMISALVFVLGFSTVFVALGASASLV
GGLIRAWSAELAIVAGIVIILMGLHFLGLTRLNILMREGRLPIPKPVGLWGAYVMGLAFAFGWTPCIGPILAAILSVAAA
EATVAKGAGLLAVYSAGLGIPFLLAALMVEQFSGLFARMKKHLAIVERVMGALMVLTGIAFLTGAITDVSVWLLNTFPAL
GTIG
>Mature_244_residues
MIHDVSIPAALLAGLVSFLSPCVLPLVPPYLIYLTGATIEHVAADESQRNSKRAVMISALVFVLGFSTVFVALGASASLV
GGLIRAWSAELAIVAGIVIILMGLHFLGLTRLNILMREGRLPIPKPVGLWGAYVMGLAFAFGWTPCIGPILAAILSVAAA
EATVAKGAGLLAVYSAGLGIPFLLAALMVEQFSGLFARMKKHLAIVERVMGALMVLTGIAFLTGAITDVSVWLLNTFPAL
GTIG

Specific function: Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spor

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 25393; Mature: 25393

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHDVSIPAALLAGLVSFLSPCVLPLVPPYLIYLTGATIEHVAADESQRNSKRAVMISAL
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHH
VFVLGFSTVFVALGASASLVGGLIRAWSAELAIVAGIVIILMGLHFLGLTRLNILMREGR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LPIPKPVGLWGAYVMGLAFAFGWTPCIGPILAAILSVAAAEATVAKGAGLLAVYSAGLGI
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCH
PFLLAALMVEQFSGLFARMKKHLAIVERVMGALMVLTGIAFLTGAITDVSVWLLNTFPAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
GTIG
CCCC
>Mature Secondary Structure
MIHDVSIPAALLAGLVSFLSPCVLPLVPPYLIYLTGATIEHVAADESQRNSKRAVMISAL
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHH
VFVLGFSTVFVALGASASLVGGLIRAWSAELAIVAGIVIILMGLHFLGLTRLNILMREGR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LPIPKPVGLWGAYVMGLAFAFGWTPCIGPILAAILSVAAAEATVAKGAGLLAVYSAGLGI
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCH
PFLLAALMVEQFSGLFARMKKHLAIVERVMGALMVLTGIAFLTGAITDVSVWLLNTFPAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
GTIG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DsbGoxidized; DsbDreduced/thiol:disulfide reductase [C]

Specific reaction: DsbDreduced/thiol:disulfide reductase + DsbCoxidized = DsbDoxidized + DsbCreduced DsbGoxidized + DsbDreduced/thiol:disulfide reductase = DsbGreduced + DsbDoxidized [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]