Click here to switch to the map view.

The map label for this gene is 86750698

Identifier: 86750698

GI number: 86750698

Start: 4112286

End: 4113425

Strand: Direct

Name: 86750698

Synonym: RPB_3588

Alternate gene names: NA

Gene position: 4112286-4113425 (Clockwise)

Preceding gene: 86750697

Following gene: 86750699

Centisome position: 77.13

GC content: 67.02

Gene sequence:

>1140_bases
ATGCGTCGCAATCAGGTCGCCGTCGTCGGCGCCGCCGAGACCACCAAGCTCGGCGTCATTCCCGACATGTCGCAGATCCA
GCTCCACGCCGACGCCGCGCTGAACGCGATGGCCGATTGCGGGCTGAAGCCGTCCGACATCGACGGCGTCGCCACCGCGG
TCGAGAGCCCGCAGCAGATCGCGCATTATCTCGGCATCACCCCGAGCTGGGTCGACGGCACGTCGGTCGGCGGCTGCTCG
TTCATGCTGCACGTCCGTCACGCGGCGGCAGCGATCGAGGCCGGGCTGTGCAAGACCGTGCTGATCACCCACGCCGAGAG
CGGCAAATCGATGATCGGCAAGCTGCCGCGCTCGATCCCCGCCGACAGCCTGCAGGGCCAGTTCGAGGCGCCCTACGGCA
TCTACGGGCCGCCGAGCCAGTTTCCGATCCCGGTGCTGCGCTTCATGAAGACCTGGGGCATCACCCACGAGCAGCTCGCG
ATGGTCGCCGTGGTGCAGCGCGAATGGGCGGCGAAGAATCCGCGCGCGACCATGAAGGACCCGATCACCGTCGCCGACGT
GCTGAACTCGCGGATGATCGCCTATCCGTTCCGGCTGCTGCAATGCTGCCTCGTCACCGACGGCGGCGGCGCGCTGATCA
TGACCTCGGCCGATCGCGCCAAGGACTTCCCGCACAAGCCGGTCTATGTGCTCGGCACCGGCGAGAGCGTGGAAACGCCG
ATGGTCAGCCAGATGGAGAGCTTCAACTCCTCGCGCGCCTTCAAGGTGGCGGGGCCGACCGCGTTCCGCGAGGCCGGCAT
CAGCCACAGCGACGTCGACCACCTGATGATCTACGACGCCTTCGCGCATCTGCCGCTGTTCGGCCTCGGCGACCTCGGCT
TCATGCCGTATGAGGAGACCGGCAAGTTCATTGCCGACGGCAACACCCGCCCCGGCGGCAAGCTGCCGCTCAACACCAAT
GGCGGCGGGCTGAGCTATATGCACTCCGGCATGTACGGCATGTACGCGCTGCAGGAGAGCGTCCGGCAGATGCGCGGCAT
CGCGCCGGCGCAGGTGGAAGGCGCGAAGATCTCGGTCTGCCACGGCGTCGGCGGCATGTTCGCGGCGTCGGGAACGATCA
TCTTTACGAACGAGAAGTAG

Upstream 100 bases:

>100_bases
CGGAGGCGCTCGAGCTCGACATGAAGCTCGAAGTCACCTTCCAGAAAATCGACGACAATCTCACCCTTCCGCAATTCCGT
CCGGCGAAGGGGTAAGCGCC

Downstream 100 bases:

>100_bases
TTCGGCGCAAGCCGCAATAGACCACGTCATCGCCGGGCTCGACCCGGCGATCCATCGCTCGAAGAAGATGGATGCGCGGG
TCAAGCCCGCGCATGACGAC

Product: thiolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MRRNQVAVVGAAETTKLGVIPDMSQIQLHADAALNAMADCGLKPSDIDGVATAVESPQQIAHYLGITPSWVDGTSVGGCS
FMLHVRHAAAAIEAGLCKTVLITHAESGKSMIGKLPRSIPADSLQGQFEAPYGIYGPPSQFPIPVLRFMKTWGITHEQLA
MVAVVQREWAAKNPRATMKDPITVADVLNSRMIAYPFRLLQCCLVTDGGGALIMTSADRAKDFPHKPVYVLGTGESVETP
MVSQMESFNSSRAFKVAGPTAFREAGISHSDVDHLMIYDAFAHLPLFGLGDLGFMPYEETGKFIADGNTRPGGKLPLNTN
GGGLSYMHSGMYGMYALQESVRQMRGIAPAQVEGAKISVCHGVGGMFAASGTIIFTNEK

Sequences:

>Translated_379_residues
MRRNQVAVVGAAETTKLGVIPDMSQIQLHADAALNAMADCGLKPSDIDGVATAVESPQQIAHYLGITPSWVDGTSVGGCS
FMLHVRHAAAAIEAGLCKTVLITHAESGKSMIGKLPRSIPADSLQGQFEAPYGIYGPPSQFPIPVLRFMKTWGITHEQLA
MVAVVQREWAAKNPRATMKDPITVADVLNSRMIAYPFRLLQCCLVTDGGGALIMTSADRAKDFPHKPVYVLGTGESVETP
MVSQMESFNSSRAFKVAGPTAFREAGISHSDVDHLMIYDAFAHLPLFGLGDLGFMPYEETGKFIADGNTRPGGKLPLNTN
GGGLSYMHSGMYGMYALQESVRQMRGIAPAQVEGAKISVCHGVGGMFAASGTIIFTNEK
>Mature_379_residues
MRRNQVAVVGAAETTKLGVIPDMSQIQLHADAALNAMADCGLKPSDIDGVATAVESPQQIAHYLGITPSWVDGTSVGGCS
FMLHVRHAAAAIEAGLCKTVLITHAESGKSMIGKLPRSIPADSLQGQFEAPYGIYGPPSQFPIPVLRFMKTWGITHEQLA
MVAVVQREWAAKNPRATMKDPITVADVLNSRMIAYPFRLLQCCLVTDGGGALIMTSADRAKDFPHKPVYVLGTGESVETP
MVSQMESFNSSRAFKVAGPTAFREAGISHSDVDHLMIYDAFAHLPLFGLGDLGFMPYEETGKFIADGNTRPGGKLPLNTN
GGGLSYMHSGMYGMYALQESVRQMRGIAPAQVEGAKISVCHGVGGMFAASGTIIFTNEK

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=389, Percent_Identity=24.9357326478149, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI302344760, Length=324, Percent_Identity=25.6172839506173, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI302344767, Length=261, Percent_Identity=26.0536398467433, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI302344762, Length=261, Percent_Identity=26.0536398467433, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17537653, Length=378, Percent_Identity=22.7513227513227, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI19921506, Length=229, Percent_Identity=27.0742358078603, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24585051, Length=229, Percent_Identity=27.0742358078603, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 40433; Mature: 40433

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRNQVAVVGAAETTKLGVIPDMSQIQLHADAALNAMADCGLKPSDIDGVATAVESPQQI
CCCCCEEEEECCCCCEECCCCCHHHEEEEHHHHHHHHHHCCCCCCCCCHHHHHHCCHHHH
AHYLGITPSWVDGTSVGGCSFMLHVRHAAAAIEAGLCKTVLITHAESGKSMIGKLPRSIP
HHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHCCCCCC
ADSLQGQFEAPYGIYGPPSQFPIPVLRFMKTWGITHEQLAMVAVVQREWAAKNPRATMKD
CHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCC
PITVADVLNSRMIAYPFRLLQCCLVTDGGGALIMTSADRAKDFPHKPVYVLGTGESVETP
CCHHHHHHCCCHHHHHHHHHHHHEEECCCCEEEEECCHHHCCCCCCCEEEEECCCCCCCH
MVSQMESFNSSRAFKVAGPTAFREAGISHSDVDHLMIYDAFAHLPLFGLGDLGFMPYEET
HHHHHHHCCCCCEEEEECCHHHHHCCCCCCCCHHHHHHHHHHHCCEECCCCCCCCCHHHC
GKFIADGNTRPGGKLPLNTNGGGLSYMHSGMYGMYALQESVRQMRGIAPAQVEGAKISVC
CCEEECCCCCCCCEEEECCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCEECCCEEEEE
HGVGGMFAASGTIIFTNEK
ECCCCCEECCCEEEEECCC
>Mature Secondary Structure
MRRNQVAVVGAAETTKLGVIPDMSQIQLHADAALNAMADCGLKPSDIDGVATAVESPQQI
CCCCCEEEEECCCCCEECCCCCHHHEEEEHHHHHHHHHHCCCCCCCCCHHHHHHCCHHHH
AHYLGITPSWVDGTSVGGCSFMLHVRHAAAAIEAGLCKTVLITHAESGKSMIGKLPRSIP
HHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHCCCCCC
ADSLQGQFEAPYGIYGPPSQFPIPVLRFMKTWGITHEQLAMVAVVQREWAAKNPRATMKD
CHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCC
PITVADVLNSRMIAYPFRLLQCCLVTDGGGALIMTSADRAKDFPHKPVYVLGTGESVETP
CCHHHHHHCCCHHHHHHHHHHHHEEECCCCEEEEECCHHHCCCCCCCEEEEECCCCCCCH
MVSQMESFNSSRAFKVAGPTAFREAGISHSDVDHLMIYDAFAHLPLFGLGDLGFMPYEET
HHHHHHHCCCCCEEEEECCHHHHHCCCCCCCCHHHHHHHHHHHCCEECCCCCCCCCHHHC
GKFIADGNTRPGGKLPLNTNGGGLSYMHSGMYGMYALQESVRQMRGIAPAQVEGAKISVC
CCEEECCCCCCCCEEEECCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCEECCCEEEEE
HGVGGMFAASGTIIFTNEK
ECCCCCEECCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]