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The map label for this gene is cyaB [H]

Identifier: 86750678

GI number: 86750678

Start: 4089872

End: 4091452

Strand: Reverse

Name: cyaB [H]

Synonym: RPB_3568

Alternate gene names: 86750678

Gene position: 4091452-4089872 (Counterclockwise)

Preceding gene: 86750680

Following gene: 86750675

Centisome position: 76.74

GC content: 64.83

Gene sequence:

>1581_bases
GTGCAGAAAGACCGAGACGACAACGACAAGCTGCGATCGCGCAGCGTGCTGACCGGCTGCCTGATCGCGTTGCTGCTGCT
CGCGCTGCCGGTGGCGGTTTGGCTCGACCTCACCCATCTCGCGGACGCGGCGCTGCGGCGGCAGGCCAACGACCTCAATT
CGGTGATCACCAGCGTGCGCGGCTACTACGCCAGCAACGTCGTCGGCCGCGTTCTCGCGCATCCCGACAACGTCCAGGTG
GTGCATGATTATGAGAGCACGCCCGGCGCCATTCCGATCCCGGCGACGCTGTCCCTCGAACTCGGCAAGGTGATCGGCGC
GCAGCAGAGCAACATCACCTATCGGTTCGTTTCCGACTATCCGTTCGCCAATCGCGCGCCGCACCAGCTCGACGGCTTCG
AGCGCGAGGCGCTGGCGACGCTGCGCAGGGATGCGTCCGAGAACGTCGTCGCCGGCACCACGGGGCTGCTCAGCGACAGC
GTGCGGCTGGTGGCGCCGGTGGTGATGGGGCAGGCCTGCGTCGCCTGCCACAACACGCACCCGGAGAGTCCAAAGCGCGA
CTGGAAGGTCGGCGACGTCCGCGGCATCCAGGAGGTGATGATCACCCAGCCGATTGCCGCCAATCTGTTCTCGTTCAAAT
TCCTGCTGGCCTATCTGGTGCTCGCGGCGGTGTCGGGCGTGTCGTTCGTCGCGATGCAGCGCCGGCAGGCGCTGAAGATC
GTGGCGATGAACAAGGAACTGGAGACCAACAACGACTTCCTCGCCTCGCTGTCGATGAAGATCTCGCGCTATATCCCGCC
GCAGATCTACAAGAGCATCTTCTCCGGCCAGAAGGACGTCGTCATCCACACCGAACGCAAGAAGCTGACGATCTTCTTCT
CGGACATCCAGAACTTCACCGCGACCACCGAGCGGCTGCAGCCCGAGCTGATCACCCAATTGCTCAACGAGTACTTCACC
GAAATGTCGGAGATCGCGCATCGTTACGGCGGCACGATCGATAAATTCATCGGTGACGCGATGCTGATCTTCTTCGGCGA
CCCGGACACCAAAGGCGACCGCGCCGACGCGCAGGCCTGCCTGCGGATGGCCTGGGCGATGCAGCGGCGCCTGGCCGAGC
TCAACGGCAAATGGCGCGCCGCCGGGATCGAACAGCCGTTCCGCGCGCGGATCGGGATCAATTCCGGCTATTGCAATGTC
GGCAATTTCGGCAGCGCGGACCGGATGGACTACACCATCATCGGCGCCGAGGCGAACCTCGCGGCGCGGCTGCAGGCGAT
CGCCGAGCCCGGCGGCATCGTCATCAGCTACGAGACCTACGCGCTGGTCAGCGACATCATCGCCGCGCACACGCTGCCGT
CGATCACCATGAAGGGCATCAGCCGCGAAGTGGTGCCCTATGCGGTCGATCATCTGCGCGACGGCAGCGAGGCGTCCGAC
GTGGTGATCGAAAAGCTGCCGGGCCTGGAGTTCTATCTCGACGCCGCCGCGATGAATCCCGCCGACAGCGACAAAGTCCG
CGCCGTGCTGGAGCAGGCGCTGGCGTCGCTGGAACGGAGGGAAGAGAAGGCGGCGGAGTAG

Upstream 100 bases:

>100_bases
CGCTGCGGGAAAAAACGGGTAGCTCTGCACCGTTGACGCTTCTCATTGCCCGCCGCCGCCTCTAGTTTGCCGCCGCTGGC
AAGGAATGGTGGGACGGCGC

Downstream 100 bases:

>100_bases
GTGCGTTTTCGTCCTGGTAGGTCTTGGGGCGATCGAAGGAGATGGATGCGGGTCAAGCCCGCGCATGACGCAGCGTTGCG
GTAATTGGCCCTTCAACCGT

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 2; Adenylyl cyclase 2; AC2 [H]

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MQKDRDDNDKLRSRSVLTGCLIALLLLALPVAVWLDLTHLADAALRRQANDLNSVITSVRGYYASNVVGRVLAHPDNVQV
VHDYESTPGAIPIPATLSLELGKVIGAQQSNITYRFVSDYPFANRAPHQLDGFEREALATLRRDASENVVAGTTGLLSDS
VRLVAPVVMGQACVACHNTHPESPKRDWKVGDVRGIQEVMITQPIAANLFSFKFLLAYLVLAAVSGVSFVAMQRRQALKI
VAMNKELETNNDFLASLSMKISRYIPPQIYKSIFSGQKDVVIHTERKKLTIFFSDIQNFTATTERLQPELITQLLNEYFT
EMSEIAHRYGGTIDKFIGDAMLIFFGDPDTKGDRADAQACLRMAWAMQRRLAELNGKWRAAGIEQPFRARIGINSGYCNV
GNFGSADRMDYTIIGAEANLAARLQAIAEPGGIVISYETYALVSDIIAAHTLPSITMKGISREVVPYAVDHLRDGSEASD
VVIEKLPGLEFYLDAAAMNPADSDKVRAVLEQALASLERREEKAAE

Sequences:

>Translated_526_residues
MQKDRDDNDKLRSRSVLTGCLIALLLLALPVAVWLDLTHLADAALRRQANDLNSVITSVRGYYASNVVGRVLAHPDNVQV
VHDYESTPGAIPIPATLSLELGKVIGAQQSNITYRFVSDYPFANRAPHQLDGFEREALATLRRDASENVVAGTTGLLSDS
VRLVAPVVMGQACVACHNTHPESPKRDWKVGDVRGIQEVMITQPIAANLFSFKFLLAYLVLAAVSGVSFVAMQRRQALKI
VAMNKELETNNDFLASLSMKISRYIPPQIYKSIFSGQKDVVIHTERKKLTIFFSDIQNFTATTERLQPELITQLLNEYFT
EMSEIAHRYGGTIDKFIGDAMLIFFGDPDTKGDRADAQACLRMAWAMQRRLAELNGKWRAAGIEQPFRARIGINSGYCNV
GNFGSADRMDYTIIGAEANLAARLQAIAEPGGIVISYETYALVSDIIAAHTLPSITMKGISREVVPYAVDHLRDGSEASD
VVIEKLPGLEFYLDAAAMNPADSDKVRAVLEQALASLERREEKAAE
>Mature_526_residues
MQKDRDDNDKLRSRSVLTGCLIALLLLALPVAVWLDLTHLADAALRRQANDLNSVITSVRGYYASNVVGRVLAHPDNVQV
VHDYESTPGAIPIPATLSLELGKVIGAQQSNITYRFVSDYPFANRAPHQLDGFEREALATLRRDASENVVAGTTGLLSDS
VRLVAPVVMGQACVACHNTHPESPKRDWKVGDVRGIQEVMITQPIAANLFSFKFLLAYLVLAAVSGVSFVAMQRRQALKI
VAMNKELETNNDFLASLSMKISRYIPPQIYKSIFSGQKDVVIHTERKKLTIFFSDIQNFTATTERLQPELITQLLNEYFT
EMSEIAHRYGGTIDKFIGDAMLIFFGDPDTKGDRADAQACLRMAWAMQRRLAELNGKWRAAGIEQPFRARIGINSGYCNV
GNFGSADRMDYTIIGAEANLAARLQAIAEPGGIVISYETYALVSDIIAAHTLPSITMKGISREVVPYAVDHLRDGSEASD
VVIEKLPGLEFYLDAAAMNPADSDKVRAVLEQALASLERREEKAAE

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI17534659, Length=229, Percent_Identity=26.2008733624454, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221330468, Length=179, Percent_Identity=29.0502793296089, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221330470, Length=179, Percent_Identity=29.0502793296089, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00072 Response_reg [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 57920; Mature: 57920

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKDRDDNDKLRSRSVLTGCLIALLLLALPVAVWLDLTHLADAALRRQANDLNSVITSVR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYYASNVVGRVLAHPDNVQVVHDYESTPGAIPIPATLSLELGKVIGAQQSNITYRFVSDY
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEECHHHHHHHCCCCCCCEEEEECCC
PFANRAPHQLDGFEREALATLRRDASENVVAGTTGLLSDSVRLVAPVVMGQACVACHNTH
CCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCHHHHHCCHHHHHHHHHHHHHHHHCCCC
PESPKRDWKVGDVRGIQEVMITQPIAANLFSFKFLLAYLVLAAVSGVSFVAMQRRQALKI
CCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
VAMNKELETNNDFLASLSMKISRYIPPQIYKSIFSGQKDVVIHTERKKLTIFFSDIQNFT
EEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCEEEEEHHHHHHHH
ATTERLQPELITQLLNEYFTEMSEIAHRYGGTIDKFIGDAMLIFFGDPDTKGDRADAQAC
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCEEEEEECCCCCCCCHHHHHHH
LRMAWAMQRRLAELNGKWRAAGIEQPFRARIGINSGYCNVGNFGSADRMDYTIIGAEANL
HHHHHHHHHHHHHHCCCEEECCCCCCCHHEECCCCCCCCCCCCCCCCCCEEEEEECCCHH
AARLQAIAEPGGIVISYETYALVSDIIAAHTLPSITMKGISREVVPYAVDHLRDGSEASD
HHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHCCCCCCHHH
VVIEKLPGLEFYLDAAAMNPADSDKVRAVLEQALASLERREEKAAE
HHHHHCCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQKDRDDNDKLRSRSVLTGCLIALLLLALPVAVWLDLTHLADAALRRQANDLNSVITSVR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYYASNVVGRVLAHPDNVQVVHDYESTPGAIPIPATLSLELGKVIGAQQSNITYRFVSDY
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEECHHHHHHHCCCCCCCEEEEECCC
PFANRAPHQLDGFEREALATLRRDASENVVAGTTGLLSDSVRLVAPVVMGQACVACHNTH
CCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCHHHHHCCHHHHHHHHHHHHHHHHCCCC
PESPKRDWKVGDVRGIQEVMITQPIAANLFSFKFLLAYLVLAAVSGVSFVAMQRRQALKI
CCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
VAMNKELETNNDFLASLSMKISRYIPPQIYKSIFSGQKDVVIHTERKKLTIFFSDIQNFT
EEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCEEEEEHHHHHHHH
ATTERLQPELITQLLNEYFTEMSEIAHRYGGTIDKFIGDAMLIFFGDPDTKGDRADAQAC
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCEEEEEECCCCCCCCHHHHHHH
LRMAWAMQRRLAELNGKWRAAGIEQPFRARIGINSGYCNVGNFGSADRMDYTIIGAEANL
HHHHHHHHHHHHHHCCCEEECCCCCCCHHEECCCCCCCCCCCCCCCCCCEEEEEECCCHH
AARLQAIAEPGGIVISYETYALVSDIIAAHTLPSITMKGISREVVPYAVDHLRDGSEASD
HHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHCCCCCCHHH
VVIEKLPGLEFYLDAAAMNPADSDKVRAVLEQALASLERREEKAAE
HHHHHCCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]