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The map label for this gene is cutL [H]

Identifier: 86750224

GI number: 86750224

Start: 3544543

End: 3546828

Strand: Reverse

Name: cutL [H]

Synonym: RPB_3111

Alternate gene names: 86750224

Gene position: 3546828-3544543 (Counterclockwise)

Preceding gene: 86750225

Following gene: 86750223

Centisome position: 66.52

GC content: 66.75

Gene sequence:

>2286_bases
GTGAACGAGCGCGTGCCGCTGGTTGGACAGCCGATCGAGCGTGTCGAGGATCCAAAGCTGCTGCGCGGACTCGGCAGCTT
CGTCGACGACGTGCATCGCGACGGCATGCTGCATGCCGCGATTCTGCGCAGCTCGGTCGCGCACGGCGTGATCCGGCGCA
TCGACGTCACCGCGGCGCGGGCGATGCCGGGCGTGCATGCGGTCTATACCGCCGAGGATATCGGCGCGGTGCCGCGGATT
CCGGTGCGGCTGTTTCCCAACGAGGCGATGGAGCCGTTCCGGCAGCCGGTGATCGCCGACGGCAAGGTCCGCTTCGTCGG
CGAGCCGATGGCGATCGTGATCGCCGACACACCGGCGCTGGCGGAGGACGCGCTCGAATTGATCGAGGCGGATATCGACC
CCCTGCCGGCGGTCACGAGGTTCGAGGACGAGGTCGCGCACGACGCGCTGCTGTTCGAGGCACACGGCTCCAACCGGGTG
TTCGACTACGAGGTCAGCCGCGGCGAGATCGACGATACCTTCGAGACCGCGCCCTACACCCGCCGCGAGCGGCTGTACGT
GCACCGCCATACCGGTATCACGATGGAGACGCGTGGCGTGGTGTCCGAATGGGACGCCGCCGCAGGCCGGATGACGTCGT
GGGGCGCCACCAAGGTCCCGTTCGCCAACCGCAAGATTCTGGCCGGGATGCTCGATCTGCCCGAAGAGCAGGTGGTGATG
ATCGAGGGTAATGCCGGCGGCAGCTTCGGCGTGCGCGGCGAATTCTTCCCGGAGGATTTCCTGGTCCCGTTCGCCGCGCG
CAAAATCGGCAGGCCGGTCAAATGGATCGAGGACCGCCGGGAGCATTTGCTCGCGGTGACCCATTCGCGCGACGTCGCCG
CCGACCTCGAAATCGCCTGCAATCGCGACGGCCGCATTCTCGCGATCCGCGCCCGGATGCAGATGAACATCGGCGCGTAT
TTCCGCACCTCGACAACGATCGCGCCGCGCAATGTCGGGCAGTTCATGCCCGGCGCCTATCGCGTGCCGCGCTATCGCGC
CGACGTCGCGGTGATCGCGTCGAACAAATCGCCGGCCGGCACCTATCGCGGTCCGGGGCGATTCGAGTCGGATTTCTTCC
GCGAGCGAATGTTCGATCTCACCGCCGATGACCTCGGCATCGATCGCGTCGAATTCCGCCGCCGCAATCTGCTAACGCCG
GAGGAACTGCCGCTGGCGTTTCCGGCGATTGCTCCGAACCCGGTCGTCACCGAACTCGACAGCGGTGCCTATGAAAAGGT
GCTCGATCTCTGCCTCGCCAAAGCGGGCTGGGCCGACAAGCAGCATCTGCAGGGGAAGCTCGTCGACGGCCGCTATCACG
GCCTCGCGGTCGGCTGTTTCGTCGAGGGCGGCGCCGCCGGTCCGCGCGAAAGTGCGCGCATGGTGCTGGAAAGCGACGGC
ACGATCTCGCTCTATGTCGGCTCTTCGGCGGTCGGGCAGGGCGTCGAGACCATCCTGATGCAGATCGCCGCCGATGCGAT
GGACCTGCCGCTCAAGGCGATCCGCGTCTTTCACGGCTCGACGACTTATGTGAAGGAAGGCTGGGGATCCTATCACTCGC
GTTCCACGGTGATGGGCGGCAACGCCGTGCTGCTCGCCGCAGCGGAGATCAAGGCACAGCTGCTGACGGCCGGCGCCGGC
CTGCTGCAATGCGCCGAGCAGGAGGTCAGCTATCAGGCCGGGCGCGTCGCCGCGCAGCACGGCGGGTCGGTCGGGCTGAA
GGAACTGGCGGCGAAGGGCATCGCCTTCGAGGCGACGTTTCACAACACCAAGCACACCTACACCTATGGCAGCCACGTCG
CGCATGTCGCGGTCGATGCCGAGACCGGACATATCGAGATCGTCGACTACGTCGCCATCGAGGATGCCGGCCGCATCATC
AATCCGCTGACGCTGCACGGCCAGGCGATCGGCTCGATCGTGCAGGGGCTCGGCGGCACGCTGCTCGAGCACTTCGTGTA
CGACGACGAGGGGCAGATGCTGTCGGGCTCGCTGGCCGACTATCTGGTTCCGCTCGCGACCGACTATCCCAACATCCGCT
CGTCGTCGATCGAGATGTGTCCGTCGCCGAACCATCCGCTTGGTGCCAAGGGCGCCGGCGAAGGCGGGACGATTCCGGTC
GGCGGGATTCTGGCGAATGCGGTCGCGGCGGCGCTGCGCGATTTTGACGTGCAGCCGAAGGCGCTGCCGCTATCTCCGGA
CCGGATCTGGCGGCTTGTGCAAGCTGCCGCAGCGCGCCCTGCTTAG

Upstream 100 bases:

>100_bases
TGCTGTCCGGCAATGTCTGCCGCTGCACCGGCTATCTGTCGATTGTGAAAGCCGTGATGGAAGCGCGACCGGCCTATCAG
CGTGAGCAGGGAGTGGGGGC

Downstream 100 bases:

>100_bases
CGAGGCGGCTAGCCGGATACTTCCGCTCTGCGGGGCCCGGTGCCCTGCTTGCGGCAGGATGACGCCCGTCTACTGATCGA
GCGGCCTCATTCTTCGTACC

Product: carbon-monoxide dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 761; Mature: 761

Protein sequence:

>761_residues
MNERVPLVGQPIERVEDPKLLRGLGSFVDDVHRDGMLHAAILRSSVAHGVIRRIDVTAARAMPGVHAVYTAEDIGAVPRI
PVRLFPNEAMEPFRQPVIADGKVRFVGEPMAIVIADTPALAEDALELIEADIDPLPAVTRFEDEVAHDALLFEAHGSNRV
FDYEVSRGEIDDTFETAPYTRRERLYVHRHTGITMETRGVVSEWDAAAGRMTSWGATKVPFANRKILAGMLDLPEEQVVM
IEGNAGGSFGVRGEFFPEDFLVPFAARKIGRPVKWIEDRREHLLAVTHSRDVAADLEIACNRDGRILAIRARMQMNIGAY
FRTSTTIAPRNVGQFMPGAYRVPRYRADVAVIASNKSPAGTYRGPGRFESDFFRERMFDLTADDLGIDRVEFRRRNLLTP
EELPLAFPAIAPNPVVTELDSGAYEKVLDLCLAKAGWADKQHLQGKLVDGRYHGLAVGCFVEGGAAGPRESARMVLESDG
TISLYVGSSAVGQGVETILMQIAADAMDLPLKAIRVFHGSTTYVKEGWGSYHSRSTVMGGNAVLLAAAEIKAQLLTAGAG
LLQCAEQEVSYQAGRVAAQHGGSVGLKELAAKGIAFEATFHNTKHTYTYGSHVAHVAVDAETGHIEIVDYVAIEDAGRII
NPLTLHGQAIGSIVQGLGGTLLEHFVYDDEGQMLSGSLADYLVPLATDYPNIRSSSIEMCPSPNHPLGAKGAGEGGTIPV
GGILANAVAAALRDFDVQPKALPLSPDRIWRLVQAAAARPA

Sequences:

>Translated_761_residues
MNERVPLVGQPIERVEDPKLLRGLGSFVDDVHRDGMLHAAILRSSVAHGVIRRIDVTAARAMPGVHAVYTAEDIGAVPRI
PVRLFPNEAMEPFRQPVIADGKVRFVGEPMAIVIADTPALAEDALELIEADIDPLPAVTRFEDEVAHDALLFEAHGSNRV
FDYEVSRGEIDDTFETAPYTRRERLYVHRHTGITMETRGVVSEWDAAAGRMTSWGATKVPFANRKILAGMLDLPEEQVVM
IEGNAGGSFGVRGEFFPEDFLVPFAARKIGRPVKWIEDRREHLLAVTHSRDVAADLEIACNRDGRILAIRARMQMNIGAY
FRTSTTIAPRNVGQFMPGAYRVPRYRADVAVIASNKSPAGTYRGPGRFESDFFRERMFDLTADDLGIDRVEFRRRNLLTP
EELPLAFPAIAPNPVVTELDSGAYEKVLDLCLAKAGWADKQHLQGKLVDGRYHGLAVGCFVEGGAAGPRESARMVLESDG
TISLYVGSSAVGQGVETILMQIAADAMDLPLKAIRVFHGSTTYVKEGWGSYHSRSTVMGGNAVLLAAAEIKAQLLTAGAG
LLQCAEQEVSYQAGRVAAQHGGSVGLKELAAKGIAFEATFHNTKHTYTYGSHVAHVAVDAETGHIEIVDYVAIEDAGRII
NPLTLHGQAIGSIVQGLGGTLLEHFVYDDEGQMLSGSLADYLVPLATDYPNIRSSSIEMCPSPNHPLGAKGAGEGGTIPV
GGILANAVAAALRDFDVQPKALPLSPDRIWRLVQAAAARPA
>Mature_761_residues
MNERVPLVGQPIERVEDPKLLRGLGSFVDDVHRDGMLHAAILRSSVAHGVIRRIDVTAARAMPGVHAVYTAEDIGAVPRI
PVRLFPNEAMEPFRQPVIADGKVRFVGEPMAIVIADTPALAEDALELIEADIDPLPAVTRFEDEVAHDALLFEAHGSNRV
FDYEVSRGEIDDTFETAPYTRRERLYVHRHTGITMETRGVVSEWDAAAGRMTSWGATKVPFANRKILAGMLDLPEEQVVM
IEGNAGGSFGVRGEFFPEDFLVPFAARKIGRPVKWIEDRREHLLAVTHSRDVAADLEIACNRDGRILAIRARMQMNIGAY
FRTSTTIAPRNVGQFMPGAYRVPRYRADVAVIASNKSPAGTYRGPGRFESDFFRERMFDLTADDLGIDRVEFRRRNLLTP
EELPLAFPAIAPNPVVTELDSGAYEKVLDLCLAKAGWADKQHLQGKLVDGRYHGLAVGCFVEGGAAGPRESARMVLESDG
TISLYVGSSAVGQGVETILMQIAADAMDLPLKAIRVFHGSTTYVKEGWGSYHSRSTVMGGNAVLLAAAEIKAQLLTAGAG
LLQCAEQEVSYQAGRVAAQHGGSVGLKELAAKGIAFEATFHNTKHTYTYGSHVAHVAVDAETGHIEIVDYVAIEDAGRII
NPLTLHGQAIGSIVQGLGGTLLEHFVYDDEGQMLSGSLADYLVPLATDYPNIRSSSIEMCPSPNHPLGAKGAGEGGTIPV
GGILANAVAAALRDFDVQPKALPLSPDRIWRLVQAAAARPA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI91823271, Length=740, Percent_Identity=23.7837837837838, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI71773480, Length=776, Percent_Identity=23.9690721649485, Blast_Score=137, Evalue=3e-32,
Organism=Escherichia coli, GI1789230, Length=770, Percent_Identity=27.5324675324675, Blast_Score=225, Evalue=8e-60,
Organism=Escherichia coli, GI1789246, Length=799, Percent_Identity=24.5306633291614, Blast_Score=200, Evalue=4e-52,
Organism=Escherichia coli, GI1786478, Length=774, Percent_Identity=26.2273901808786, Blast_Score=160, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17539860, Length=786, Percent_Identity=20.4834605597964, Blast_Score=118, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32566215, Length=700, Percent_Identity=20.1428571428571, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI17737937, Length=727, Percent_Identity=24.0715268225585, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24647193, Length=782, Percent_Identity=21.7391304347826, Blast_Score=104, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 82294; Mature: 82294

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNERVPLVGQPIERVEDPKLLRGLGSFVDDVHRDGMLHAAILRSSVAHGVIRRIDVTAAR
CCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
AMPGVHAVYTAEDIGAVPRIPVRLFPNEAMEPFRQPVIADGKVRFVGEPMAIVIADTPAL
CCCCCEEEEEHHHCCCCCCCCEEECCCHHHHHHHCCCCCCCEEEEECCCEEEEEECCCHH
AEDALELIEADIDPLPAVTRFEDEVAHDALLFEAHGSNRVFDYEVSRGEIDDTFETAPYT
HHHHHHHHHCCCCCCCCHHHHHHHHHCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCC
RRERLYVHRHTGITMETRGVVSEWDAAAGRMTSWGATKVPFANRKILAGMLDLPEEQVVM
CCCEEEEEECCCEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEE
IEGNAGGSFGVRGEFFPEDFLVPFAARKIGRPVKWIEDRREHLLAVTHSRDVAADLEIAC
EECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCCCCCEEEEE
NRDGRILAIRARMQMNIGAYFRTSTTIAPRNVGQFMPGAYRVPRYRADVAVIASNKSPAG
CCCCCEEEEEEEEEECCCEEEEECCEECCCCHHHCCCCCCCCCCEECCEEEEECCCCCCC
TYRGPGRFESDFFRERMFDLTADDLGIDRVEFRRRNLLTPEELPLAFPAIAPNPVVTELD
CCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHCCEECCCCCCCCCEECCC
SGAYEKVLDLCLAKAGWADKQHLQGKLVDGRYHGLAVGCFVEGGAAGPRESARMVLESDG
CCHHHHHHHHHHHHCCCCCCHHCCCEEECCEECCEEEEEEEECCCCCCCHHCEEEEECCC
TISLYVGSSAVGQGVETILMQIAADAMDLPLKAIRVFHGSTTYVKEGWGSYHSRSTVMGG
EEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEECCCCCCCCCCCEEECC
NAVLLAAAEIKAQLLTAGAGLLQCAEQEVSYQAGRVAAQHGGSVGLKELAAKGIAFEATF
CEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEEEEEE
HNTKHTYTYGSHVAHVAVDAETGHIEIVDYVAIEDAGRIINPLTLHGQAIGSIVQGLGGT
CCCCEEEEECCEEEEEEEECCCCCEEEEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHH
LLEHFVYDDEGQMLSGSLADYLVPLATDYPNIRSSSIEMCPSPNHPLGAKGAGEGGTIPV
HHHHHEECCCCCEECCCHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCH
GGILANAVAAALRDFDVQPKALPLSPDRIWRLVQAAAARPA
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNERVPLVGQPIERVEDPKLLRGLGSFVDDVHRDGMLHAAILRSSVAHGVIRRIDVTAAR
CCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
AMPGVHAVYTAEDIGAVPRIPVRLFPNEAMEPFRQPVIADGKVRFVGEPMAIVIADTPAL
CCCCCEEEEEHHHCCCCCCCCEEECCCHHHHHHHCCCCCCCEEEEECCCEEEEEECCCHH
AEDALELIEADIDPLPAVTRFEDEVAHDALLFEAHGSNRVFDYEVSRGEIDDTFETAPYT
HHHHHHHHHCCCCCCCCHHHHHHHHHCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCC
RRERLYVHRHTGITMETRGVVSEWDAAAGRMTSWGATKVPFANRKILAGMLDLPEEQVVM
CCCEEEEEECCCEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEE
IEGNAGGSFGVRGEFFPEDFLVPFAARKIGRPVKWIEDRREHLLAVTHSRDVAADLEIAC
EECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCCCCCEEEEE
NRDGRILAIRARMQMNIGAYFRTSTTIAPRNVGQFMPGAYRVPRYRADVAVIASNKSPAG
CCCCCEEEEEEEEEECCCEEEEECCEECCCCHHHCCCCCCCCCCEECCEEEEECCCCCCC
TYRGPGRFESDFFRERMFDLTADDLGIDRVEFRRRNLLTPEELPLAFPAIAPNPVVTELD
CCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHCCEECCCCCCCCCEECCC
SGAYEKVLDLCLAKAGWADKQHLQGKLVDGRYHGLAVGCFVEGGAAGPRESARMVLESDG
CCHHHHHHHHHHHHCCCCCCHHCCCEEECCEECCEEEEEEEECCCCCCCHHCEEEEECCC
TISLYVGSSAVGQGVETILMQIAADAMDLPLKAIRVFHGSTTYVKEGWGSYHSRSTVMGG
EEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEECCCCCCCCCCCEEECC
NAVLLAAAEIKAQLLTAGAGLLQCAEQEVSYQAGRVAAQHGGSVGLKELAAKGIAFEATF
CEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEEEEEE
HNTKHTYTYGSHVAHVAVDAETGHIEIVDYVAIEDAGRIINPLTLHGQAIGSIVQGLGGT
CCCCEEEEECCEEEEEEEECCCCCEEEEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHH
LLEHFVYDDEGQMLSGSLADYLVPLATDYPNIRSSSIEMCPSPNHPLGAKGAGEGGTIPV
HHHHHEECCCCCEECCCHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCH
GGILANAVAAALRDFDVQPKALPLSPDRIWRLVQAAAARPA
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]