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The map label for this gene is yogA [H]

Identifier: 86750198

GI number: 86750198

Start: 3515336

End: 3516349

Strand: Reverse

Name: yogA [H]

Synonym: RPB_3084

Alternate gene names: 86750198

Gene position: 3516349-3515336 (Counterclockwise)

Preceding gene: 86750199

Following gene: 86750197

Centisome position: 65.95

GC content: 64.69

Gene sequence:

>1014_bases
ATGCGTGCAGTGCTGCTTCGTGACCACGGCGGTCTCGACCAGATGGCTCATGTCGAGGATTTCGCCACTCCGGAGCCCGG
CGAAGGCGACGTGCTGATCAAGGTCAAGGCGACGTCCTACAATTATCACGACATCTTCACGCGCCGCGGGATGCCCGGCA
TCCGCATTCCAATGCCTATCATCATGGGAATCGACATCGCCGGCGAAGTCGCTGCGCTCGGCGCGGGGGTCGAAGGCTGG
AATGTCGGCGACCGCGTGTTGATCGATCCGATCAACCGGGTCGAAGGCGGTTTGATGGGCGAAACGCGCGATGGCGGTCT
CGCCGAATACTGCGTCACGCGTGCGCACCAGCTGATCGCGCTGCCCGACGATATCTCGTTCGAGCAGGCATCGTGCCTGC
CGGTGGCGTACGGCACCGCGCTGCGGATGATGACCACCATCGGCCATGTCTCGGCGGGCGAGAAGGTGCTGATCCTCGGC
GCGTCCGGCGGCGTCGGCATCTGCTGCGTGCAACTCGCCAAGGCGGCGGGCGCCTATGTGATCGCCTGTGCTGGATCGGC
GGAGAAGGGCGAGCGCCTGATGGAGATCGGCGCCGACGAGGTCATTCTCTACAACGAAGTCGACTTCATGCAGGAATGCC
GCGCCCGCCACGGCAAGCCGCGTGCCGGCAAGGCTTCGAAAGGGGCGGGGGTCGACATGGTCGTCAACTTCACCGGCGGC
GACAGCTGGGTGCCTTCGCTGAAGTGCCTGCGGAAAGGCGGCCGGCTGGTGACTTGCGGCGCCACCGCGGGGTTCGATCC
GACCGAGGACATCCGCTTCATCTGGACCTTCGAACTGCAGATCCTCGGTTCGAACGGCTGGGAGCGCGAGGACATTCTCA
AGCTGTTCGAGCTCATCCGCGCCGGCAAGATGAAGGCCGTCATCGATCGCACGTTCCCGCTCGAGGGCGCGATCGAGGCG
ATGGGCGTTCTCGAAGACCGCAAGGTGCTCGGCAAGCTCGTGGTGACACCATGA

Upstream 100 bases:

>100_bases
GTCCAGCTTCGGCGTGGTCATCGAGTTCTCTGAATAATCCAAGCCACCGCCTCCGGCGCGCCAGAGCGCCGCAACAGACA
AAGCGAAAAAGGAGAAATGA

Downstream 100 bases:

>100_bases
GCACCGCCGCGGTGAAGACGCTCGGCATTGCCGAGCTGCAGGTGATGGCCGACCGCGCCCCTTTCATCGCGTTCTGCCAG
TTGAAGGTGACGGAGGCCGA

Product: alcohol dehydrogenase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MRAVLLRDHGGLDQMAHVEDFATPEPGEGDVLIKVKATSYNYHDIFTRRGMPGIRIPMPIIMGIDIAGEVAALGAGVEGW
NVGDRVLIDPINRVEGGLMGETRDGGLAEYCVTRAHQLIALPDDISFEQASCLPVAYGTALRMMTTIGHVSAGEKVLILG
ASGGVGICCVQLAKAAGAYVIACAGSAEKGERLMEIGADEVILYNEVDFMQECRARHGKPRAGKASKGAGVDMVVNFTGG
DSWVPSLKCLRKGGRLVTCGATAGFDPTEDIRFIWTFELQILGSNGWEREDILKLFELIRAGKMKAVIDRTFPLEGAIEA
MGVLEDRKVLGKLVVTP

Sequences:

>Translated_337_residues
MRAVLLRDHGGLDQMAHVEDFATPEPGEGDVLIKVKATSYNYHDIFTRRGMPGIRIPMPIIMGIDIAGEVAALGAGVEGW
NVGDRVLIDPINRVEGGLMGETRDGGLAEYCVTRAHQLIALPDDISFEQASCLPVAYGTALRMMTTIGHVSAGEKVLILG
ASGGVGICCVQLAKAAGAYVIACAGSAEKGERLMEIGADEVILYNEVDFMQECRARHGKPRAGKASKGAGVDMVVNFTGG
DSWVPSLKCLRKGGRLVTCGATAGFDPTEDIRFIWTFELQILGSNGWEREDILKLFELIRAGKMKAVIDRTFPLEGAIEA
MGVLEDRKVLGKLVVTP
>Mature_337_residues
MRAVLLRDHGGLDQMAHVEDFATPEPGEGDVLIKVKATSYNYHDIFTRRGMPGIRIPMPIIMGIDIAGEVAALGAGVEGW
NVGDRVLIDPINRVEGGLMGETRDGGLAEYCVTRAHQLIALPDDISFEQASCLPVAYGTALRMMTTIGHVSAGEKVLILG
ASGGVGICCVQLAKAAGAYVIACAGSAEKGERLMEIGADEVILYNEVDFMQECRARHGKPRAGKASKGAGVDMVVNFTGG
DSWVPSLKCLRKGGRLVTCGATAGFDPTEDIRFIWTFELQILGSNGWEREDILKLFELIRAGKMKAVIDRTFPLEGAIEA
MGVLEDRKVLGKLVVTP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=350, Percent_Identity=30.2857142857143, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI22538444, Length=350, Percent_Identity=30.2857142857143, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI194239674, Length=344, Percent_Identity=28.7790697674419, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI13236495, Length=344, Percent_Identity=28.7790697674419, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI194239676, Length=214, Percent_Identity=33.1775700934579, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI18379349, Length=329, Percent_Identity=27.6595744680851, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI24308257, Length=364, Percent_Identity=28.8461538461538, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI47519420, Length=382, Percent_Identity=25.3926701570681, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI67078404, Length=339, Percent_Identity=26.5486725663717, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI28557745, Length=251, Percent_Identity=29.0836653386454, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI67078406, Length=303, Percent_Identity=27.3927392739274, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI41872631, Length=252, Percent_Identity=26.5873015873016, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI197927207, Length=195, Percent_Identity=27.6923076923077, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1790485, Length=359, Percent_Identity=28.133704735376, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1789651, Length=280, Percent_Identity=29.2857142857143, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082125, Length=185, Percent_Identity=31.8918918918919, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788075, Length=351, Percent_Identity=24.2165242165242, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790045, Length=338, Percent_Identity=26.0355029585799, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=342, Percent_Identity=26.0233918128655, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17536829, Length=240, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=350, Percent_Identity=28.8571428571429, Blast_Score=119, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6324486, Length=352, Percent_Identity=26.1363636363636, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6323961, Length=352, Percent_Identity=24.7159090909091, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6323729, Length=340, Percent_Identity=25.5882352941176, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319621, Length=345, Percent_Identity=25.7971014492754, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319955, Length=315, Percent_Identity=26.031746031746, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322619, Length=315, Percent_Identity=26.031746031746, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45550423, Length=331, Percent_Identity=25.3776435045317, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI19920632, Length=160, Percent_Identity=30, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI221330659, Length=160, Percent_Identity=30, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24581345, Length=246, Percent_Identity=25.609756097561, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 36087; Mature: 36087

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVLLRDHGGLDQMAHVEDFATPEPGEGDVLIKVKATSYNYHDIFTRRGMPGIRIPMPI
CEEEEEECCCCCCHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCE
IMGIDIAGEVAALGAGVEGWNVGDRVLIDPINRVEGGLMGETRDGGLAEYCVTRAHQLIA
EEECCCCCCHHHHCCCCCCCCCCCEEEECCHHHHCCCCCCCCCCCCHHHHHHHHCCEEEE
LPDDISFEQASCLPVAYGTALRMMTTIGHVSAGEKVLILGASGGVGICCVQLAKAAGAYV
CCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEE
IACAGSAEKGERLMEIGADEVILYNEVDFMQECRARHGKPRAGKASKGAGVDMVVNFTGG
EEECCCCHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCC
DSWVPSLKCLRKGGRLVTCGATAGFDPTEDIRFIWTFELQILGSNGWEREDILKLFELIR
CCCCHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHH
AGKMKAVIDRTFPLEGAIEAMGVLEDRKVLGKLVVTP
CCCEEEEHCCCCCCCHHHHHHHHHHHHHHHCEEECCC
>Mature Secondary Structure
MRAVLLRDHGGLDQMAHVEDFATPEPGEGDVLIKVKATSYNYHDIFTRRGMPGIRIPMPI
CEEEEEECCCCCCHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCE
IMGIDIAGEVAALGAGVEGWNVGDRVLIDPINRVEGGLMGETRDGGLAEYCVTRAHQLIA
EEECCCCCCHHHHCCCCCCCCCCCEEEECCHHHHCCCCCCCCCCCCHHHHHHHHCCEEEE
LPDDISFEQASCLPVAYGTALRMMTTIGHVSAGEKVLILGASGGVGICCVQLAKAAGAYV
CCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEE
IACAGSAEKGERLMEIGADEVILYNEVDFMQECRARHGKPRAGKASKGAGVDMVVNFTGG
EEECCCCHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCC
DSWVPSLKCLRKGGRLVTCGATAGFDPTEDIRFIWTFELQILGSNGWEREDILKLFELIR
CCCCHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHH
AGKMKAVIDRTFPLEGAIEAMGVLEDRKVLGKLVVTP
CCCEEEEHCCCCCCCHHHHHHHHHHHHHHHCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]