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The map label for this gene is thcR [H]

Identifier: 86750162

GI number: 86750162

Start: 3469155

End: 3470147

Strand: Reverse

Name: thcR [H]

Synonym: RPB_3045

Alternate gene names: 86750162

Gene position: 3470147-3469155 (Counterclockwise)

Preceding gene: 86750169

Following gene: 86750161

Centisome position: 65.09

GC content: 65.16

Gene sequence:

>993_bases
ATGTCCGACGCTTCCGCGAGCGCCATCGTCCCCGATTACCCGCTGAATCGGACCCCGGTCGTCCACACCACAGACATCGC
GGAAATGCGCCACGCACTGATCAATTTCTATGGTGCACGGGCGTTCTCGGCGGAGGCCGAGGGGTTCGAGGGGTTCGGCA
GCTTCGTCAAGCTCGACGTGACGGCGTTCGGCTTTTGCCGCTACGCCTCGCAGGCTGTCGCGGAGTTTTCCGAAACCGAT
TTCGCGCGGCTGCAGATCGCGTTATGCGGCACCGGCCGGACCACCTCGGGCGGCTCGAGTGTCGAGGTCGACCCTTCGCG
CTGGTGTGTTTCGTCGCCGGGGGCGCCGACGGTGCTGGAGTTCGGCGCCGACTACGAGCAGCTCATCATCCGGTTCTCCA
ATGAAAAGCTGATGGCCACGCTGGAGGCGATGCTGGGTGTCAAGCCGCGCGGCCGGCTGGTGTTCGCGCCATCGGTGCGG
ATCGACGATTGCGGCGCGCGTGCGCTGCGCGATCTCGGCCTGTTTCTCGCCCGGCATGTCGATCCGGCGCAGGCCCCGCT
GCCGCCGCTGATGCTGCGCGAACTCGAACATACGCTGATGGTGTCGCTGCTCAGCGTGGCGCGGCACAATTTCAGCGACC
AGCTCGACCGCGATGCGCCGGACTGCGCGCCGGACTATGTTCGCGTCGCGGAGGAGTTCATCGCGGCGTCTTGGAACAGG
GCGATCACCATCAACGATCTCGCCGCCGTGACCAATGTCGGGGTCCGCAGCCTGTTCAAATCGTTTCAAAAGCACCGTGG
CTATTCGCCGATGGCGTTCGCCAAGACGGTGCGGCTCAACAAGGCCCGCGAAATGCTGCTGCAGGGCGATCCGTCGCGCT
CGGTCACCTCGGTCGCGTTCGCCTGCGGCTTCAGCAATCTCGGCCATTTCGCCCACGACTATCGCCAGAAACACGGAGAA
TTGCCGTCGGAAACGTTGGCCCGGGCGCGCTGA

Upstream 100 bases:

>100_bases
TCGGTATTGAGCGGTGGGAGCGGTGTCGGACATCTAGGCTGGCGCCGAGCCTGGCTCGTCACAGCCGGGCAAAACTGGTT
CTGGACGGAGTCCTCACCGC

Downstream 100 bases:

>100_bases
CCGGACGCGCCCCTGGCGGCGGCGTGCGACGGTTAGCCGAGATGCGCATAGGCAGCTGCAGCCGGCTCCGCTAGACGGGG
AGTGTGATATCACTGAAGCG

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MSDASASAIVPDYPLNRTPVVHTTDIAEMRHALINFYGARAFSAEAEGFEGFGSFVKLDVTAFGFCRYASQAVAEFSETD
FARLQIALCGTGRTTSGGSSVEVDPSRWCVSSPGAPTVLEFGADYEQLIIRFSNEKLMATLEAMLGVKPRGRLVFAPSVR
IDDCGARALRDLGLFLARHVDPAQAPLPPLMLRELEHTLMVSLLSVARHNFSDQLDRDAPDCAPDYVRVAEEFIAASWNR
AITINDLAAVTNVGVRSLFKSFQKHRGYSPMAFAKTVRLNKAREMLLQGDPSRSVTSVAFACGFSNLGHFAHDYRQKHGE
LPSETLARAR

Sequences:

>Translated_330_residues
MSDASASAIVPDYPLNRTPVVHTTDIAEMRHALINFYGARAFSAEAEGFEGFGSFVKLDVTAFGFCRYASQAVAEFSETD
FARLQIALCGTGRTTSGGSSVEVDPSRWCVSSPGAPTVLEFGADYEQLIIRFSNEKLMATLEAMLGVKPRGRLVFAPSVR
IDDCGARALRDLGLFLARHVDPAQAPLPPLMLRELEHTLMVSLLSVARHNFSDQLDRDAPDCAPDYVRVAEEFIAASWNR
AITINDLAAVTNVGVRSLFKSFQKHRGYSPMAFAKTVRLNKAREMLLQGDPSRSVTSVAFACGFSNLGHFAHDYRQKHGE
LPSETLARAR
>Mature_329_residues
SDASASAIVPDYPLNRTPVVHTTDIAEMRHALINFYGARAFSAEAEGFEGFGSFVKLDVTAFGFCRYASQAVAEFSETDF
ARLQIALCGTGRTTSGGSSVEVDPSRWCVSSPGAPTVLEFGADYEQLIIRFSNEKLMATLEAMLGVKPRGRLVFAPSVRI
DDCGARALRDLGLFLARHVDPAQAPLPPLMLRELEHTLMVSLLSVARHNFSDQLDRDAPDCAPDYVRVAEEFIAASWNRA
ITINDLAAVTNVGVRSLFKSFQKHRGYSPMAFAKTVRLNKAREMLLQGDPSRSVTSVAFACGFSNLGHFAHDYRQKHGEL
PSETLARAR

Specific function: Probably involved in the positive regulation of the thc operon for the degradation of the thiocarbamate herbicide EPTC [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 36153; Mature: 36022

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDASASAIVPDYPLNRTPVVHTTDIAEMRHALINFYGARAFSAEAEGFEGFGSFVKLDV
CCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHCHHHCCCCCCCHHCCCEEEEHH
TAFGFCRYASQAVAEFSETDFARLQIALCGTGRTTSGGSSVEVDPSRWCVSSPGAPTVLE
HHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCEEEECHHHCEECCCCCCHHHH
FGADYEQLIIRFSNEKLMATLEAMLGVKPRGRLVFAPSVRIDDCGARALRDLGLFLARHV
CCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCC
DPAQAPLPPLMLRELEHTLMVSLLSVARHNFSDQLDRDAPDCAPDYVRVAEEFIAASWNR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
AITINDLAAVTNVGVRSLFKSFQKHRGYSPMAFAKTVRLNKAREMLLQGDPSRSVTSVAF
EEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ACGFSNLGHFAHDYRQKHGELPSETLARAR
HHCHHHHHHHHHHHHHHHCCCCHHHHHCCC
>Mature Secondary Structure 
SDASASAIVPDYPLNRTPVVHTTDIAEMRHALINFYGARAFSAEAEGFEGFGSFVKLDV
CCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHCHHHCCCCCCCHHCCCEEEEHH
TAFGFCRYASQAVAEFSETDFARLQIALCGTGRTTSGGSSVEVDPSRWCVSSPGAPTVLE
HHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCEEEECHHHCEECCCCCCHHHH
FGADYEQLIIRFSNEKLMATLEAMLGVKPRGRLVFAPSVRIDDCGARALRDLGLFLARHV
CCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCC
DPAQAPLPPLMLRELEHTLMVSLLSVARHNFSDQLDRDAPDCAPDYVRVAEEFIAASWNR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
AITINDLAAVTNVGVRSLFKSFQKHRGYSPMAFAKTVRLNKAREMLLQGDPSRSVTSVAF
EEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ACGFSNLGHFAHDYRQKHGELPSETLARAR
HHCHHHHHHHHHHHHHHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7836301 [H]