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The map label for this gene is aapM [H]

Identifier: 86750027

GI number: 86750027

Start: 3317374

End: 3318879

Strand: Reverse

Name: aapM [H]

Synonym: RPB_2910

Alternate gene names: 86750027

Gene position: 3318879-3317374 (Counterclockwise)

Preceding gene: 86750028

Following gene: 86750026

Centisome position: 62.25

GC content: 67.6

Gene sequence:

>1506_bases
ATGAGCGAACTCGGTTCGATCACGCCGGCCTTCGTGCGCGCCGAGCTGGTGCCCGAGCGCGCCGCGCCGGTGAAGACCAC
CGGCTTCATCGGCGTGATGCGGGGGCGGCTGTTCAATTCGCCCACCAACATCCTGCTGACCATCGTCGGCGCGCTGCTGA
TGTACTTCACCGTGGTGCCGACGGTGAAATTTCTGCTGGTGGACGCGGTCTGGACCGGCAGCAACCGCACCGATTGCCTG
GCCGAAACGCTGCATCGCGACGTCGGCGCGTGCTGGCCGTTCGTGCAGGCGAAGGCTTCGCAATTCGTCTACGGCTTCTA
TCCGCAGCCGGAGCGCTGGCGCGTCGACCTGACCTTCGCGCTCGCCGCCTTGCTGCTGCTGCCGCTCTTGATCCCGCGCG
CGCCGGCGAAGACGTTGAATGCCGGATTGTTCTTCGTCGCTTTCCCGGTGCTTGCGTTCTTTCTGCTGCATGGCGGCGGG
CTGCAGGGCTTCATGGTGAGCTGGACCGCGGACCTGCTGTCCGGCCTGGTCGGCAGTCTCGGCGAAGCGGGCAGCGAGCT
CGCGCGCGGCGGCGCGCTCGCGGTCGGCATCGGCAAGCCGGTGCTGTGGATCGCCACCGCGCTGAGCTGGCTGATCGCGC
CGCTGGTCTGGCTGCGCGACTGGATCGCGGCCTCCGGCCAGCCGGTGTGGATCGATCTCGGCCTGACGGCGCTGATCGTC
ACCGCGCTGGTCGCCGTTCTGACCGGGCTGCGCAACGGCGGACGACCGCTGCTAATGACGCTCGCGACCTTCATCGGCAT
CGCCGTGGTGATTGCTTGGCTGCGGCTCGATCGCGGCGGCTTGCCGATCGTCGGCACGCGGCAATGGGGCGGATTGCTGG
TGACGCTGGTCGTCTCGGTCACCGGCATCGTCGCCTCGATGCCGATCGGCATCGCGCTGGCGCTCGGCCGGCGCTCGACG
ATTCCGCTGATCCGGCTGTTCTCGGTCGGCTTCATCGAGTTCTGGCGCGGCGTGCCGCTGATCACCGTGCTGTTCTTCGC
GACCTATATGCTGCCGCTGTTCCTGCCCGGCAACTTCACCATCGACGGGCTGATGCGGGTGCTGATCGGCGTCGCGCTGT
TCGCCGGCGCCTACAACGCCGAAGTGGTGCGCGGCGGGCTCAACGCGATTCCGCGCGGCCAGGCCGAAGCCGCCAGCGCG
CTCGGGCTGTCCTATGCCAAGACCACGGGTCTGATCGTGCTGCCGCAGGCGCTGCGCCACGTCATCCCGGGCCTCGTCAA
CAGCTTCATCGCGCTGTTCAAGGACACCTCGCTGGTGTCGATCGTGGCGCTGTTCGATCTCCTGGGCCAGCTCCGCGCCG
CCTTCGCCGATCCGACCTGGTCGACGCCGACCACGCTGTTCACCGGCTTCGCCTTCACCGGGCTGATCTACTTCGTGTTC
TGCTTCGGCATGTCGCGCTATTCGTTGTTCGTCGAACATCGGCTCAATGCCCACCGGCGCACCTGA

Upstream 100 bases:

>100_bases
AGGTGATCGCGATCACCATGGGCGTGTATCTGCTGATCTCGCTGATCACCAGCGCGCTGATGAGCCTGTACAGTTGGCGG
ATCAACCGGAGCATGGGCGC

Downstream 100 bases:

>100_bases
CAGAGGACTCTCGTTGATGGCGGAGAAACCGATCGTCTCGATCGCGGCGCTGAACAAATGGTACGGCGATTTCCACGTGC
TGCGCGACATCAATCTCGAT

Product: polar amino acid ABC transporter, inner membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MSELGSITPAFVRAELVPERAAPVKTTGFIGVMRGRLFNSPTNILLTIVGALLMYFTVVPTVKFLLVDAVWTGSNRTDCL
AETLHRDVGACWPFVQAKASQFVYGFYPQPERWRVDLTFALAALLLLPLLIPRAPAKTLNAGLFFVAFPVLAFFLLHGGG
LQGFMVSWTADLLSGLVGSLGEAGSELARGGALAVGIGKPVLWIATALSWLIAPLVWLRDWIAASGQPVWIDLGLTALIV
TALVAVLTGLRNGGRPLLMTLATFIGIAVVIAWLRLDRGGLPIVGTRQWGGLLVTLVVSVTGIVASMPIGIALALGRRST
IPLIRLFSVGFIEFWRGVPLITVLFFATYMLPLFLPGNFTIDGLMRVLIGVALFAGAYNAEVVRGGLNAIPRGQAEAASA
LGLSYAKTTGLIVLPQALRHVIPGLVNSFIALFKDTSLVSIVALFDLLGQLRAAFADPTWSTPTTLFTGFAFTGLIYFVF
CFGMSRYSLFVEHRLNAHRRT

Sequences:

>Translated_501_residues
MSELGSITPAFVRAELVPERAAPVKTTGFIGVMRGRLFNSPTNILLTIVGALLMYFTVVPTVKFLLVDAVWTGSNRTDCL
AETLHRDVGACWPFVQAKASQFVYGFYPQPERWRVDLTFALAALLLLPLLIPRAPAKTLNAGLFFVAFPVLAFFLLHGGG
LQGFMVSWTADLLSGLVGSLGEAGSELARGGALAVGIGKPVLWIATALSWLIAPLVWLRDWIAASGQPVWIDLGLTALIV
TALVAVLTGLRNGGRPLLMTLATFIGIAVVIAWLRLDRGGLPIVGTRQWGGLLVTLVVSVTGIVASMPIGIALALGRRST
IPLIRLFSVGFIEFWRGVPLITVLFFATYMLPLFLPGNFTIDGLMRVLIGVALFAGAYNAEVVRGGLNAIPRGQAEAASA
LGLSYAKTTGLIVLPQALRHVIPGLVNSFIALFKDTSLVSIVALFDLLGQLRAAFADPTWSTPTTLFTGFAFTGLIYFVF
CFGMSRYSLFVEHRLNAHRRT
>Mature_500_residues
SELGSITPAFVRAELVPERAAPVKTTGFIGVMRGRLFNSPTNILLTIVGALLMYFTVVPTVKFLLVDAVWTGSNRTDCLA
ETLHRDVGACWPFVQAKASQFVYGFYPQPERWRVDLTFALAALLLLPLLIPRAPAKTLNAGLFFVAFPVLAFFLLHGGGL
QGFMVSWTADLLSGLVGSLGEAGSELARGGALAVGIGKPVLWIATALSWLIAPLVWLRDWIAASGQPVWIDLGLTALIVT
ALVAVLTGLRNGGRPLLMTLATFIGIAVVIAWLRLDRGGLPIVGTRQWGGLLVTLVVSVTGIVASMPIGIALALGRRSTI
PLIRLFSVGFIEFWRGVPLITVLFFATYMLPLFLPGNFTIDGLMRVLIGVALFAGAYNAEVVRGGLNAIPRGQAEAASAL
GLSYAKTTGLIVLPQALRHVIPGLVNSFIALFKDTSLVSIVALFDLLGQLRAAFADPTWSTPTTLFTGFAFTGLIYFVFC
FGMSRYSLFVEHRLNAHRRT

Specific function: Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as efflux of these amino acids. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082239, Length=220, Percent_Identity=58.6363636363636, Blast_Score=255, Evalue=5e-69,
Organism=Escherichia coli, GI1788226, Length=206, Percent_Identity=34.9514563106796, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1786873, Length=210, Percent_Identity=30.952380952381, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788646, Length=214, Percent_Identity=30.3738317757009, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787087, Length=139, Percent_Identity=35.2517985611511, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1787030, Length=160, Percent_Identity=33.125, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786874, Length=174, Percent_Identity=27.5862068965517, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788645, Length=206, Percent_Identity=28.6407766990291, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI48994930, Length=132, Percent_Identity=28.7878787878788, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787086, Length=171, Percent_Identity=26.3157894736842, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 53856; Mature: 53725

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELGSITPAFVRAELVPERAAPVKTTGFIGVMRGRLFNSPTNILLTIVGALLMYFTVVP
CCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TVKFLLVDAVWTGSNRTDCLAETLHRDVGACWPFVQAKASQFVYGFYPQPERWRVDLTFA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEHHHHH
LAALLLLPLLIPRAPAKTLNAGLFFVAFPVLAFFLLHGGGLQGFMVSWTADLLSGLVGSL
HHHHHHHHHHCCCCCCHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
GEAGSELARGGALAVGIGKPVLWIATALSWLIAPLVWLRDWIAASGQPVWIDLGLTALIV
HHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHH
TALVAVLTGLRNGGRPLLMTLATFIGIAVVIAWLRLDRGGLPIVGTRQWGGLLVTLVVSV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHH
TGIVASMPIGIALALGRRSTIPLIRLFSVGFIEFWRGVPLITVLFFATYMLPLFLPGNFT
HHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCC
IDGLMRVLIGVALFAGAYNAEVVRGGLNAIPRGQAEAASALGLSYAKTTGLIVLPQALRH
HHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHCCHHHHHCCEEEEHHHHHH
VIPGLVNSFIALFKDTSLVSIVALFDLLGQLRAAFADPTWSTPTTLFTGFAFTGLIYFVF
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
CFGMSRYSLFVEHRLNAHRRT
HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SELGSITPAFVRAELVPERAAPVKTTGFIGVMRGRLFNSPTNILLTIVGALLMYFTVVP
CCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TVKFLLVDAVWTGSNRTDCLAETLHRDVGACWPFVQAKASQFVYGFYPQPERWRVDLTFA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEHHHHH
LAALLLLPLLIPRAPAKTLNAGLFFVAFPVLAFFLLHGGGLQGFMVSWTADLLSGLVGSL
HHHHHHHHHHCCCCCCHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
GEAGSELARGGALAVGIGKPVLWIATALSWLIAPLVWLRDWIAASGQPVWIDLGLTALIV
HHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHH
TALVAVLTGLRNGGRPLLMTLATFIGIAVVIAWLRLDRGGLPIVGTRQWGGLLVTLVVSV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHH
TGIVASMPIGIALALGRRSTIPLIRLFSVGFIEFWRGVPLITVLFFATYMLPLFLPGNFT
HHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCC
IDGLMRVLIGVALFAGAYNAEVVRGGLNAIPRGQAEAASALGLSYAKTTGLIVLPQALRH
HHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHCCHHHHHCCEEEEHHHHHH
VIPGLVNSFIALFKDTSLVSIVALFDLLGQLRAAFADPTWSTPTTLFTGFAFTGLIYFVF
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
CFGMSRYSLFVEHRLNAHRRT
HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8898392 [H]