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The map label for this gene is ntrY [H]

Identifier: 86749998

GI number: 86749998

Start: 3279161

End: 3281449

Strand: Reverse

Name: ntrY [H]

Synonym: RPB_2881

Alternate gene names: 86749998

Gene position: 3281449-3279161 (Counterclockwise)

Preceding gene: 86749999

Following gene: 86749997

Centisome position: 61.55

GC content: 66.4

Gene sequence:

>2289_bases
ATGACCAGCGCAGAGACGTCGACCCCAACCGTTGACGACCCGTCGATCGCCGAGCCGCGCGCCGCCTTCTGGCGCCGGCT
GCTGGCGCCGATCGCGGTGTGCGTGGCGCTGCTGTCGGCCTTCCTCACCTTCGTCATCCTGACCGGACTGACGCCGATTG
CGCCCACCCGGGCCGTCGTCGTCACCTTCCTGCTGATCAACGGCGCCACCATCCTGCTGCTGGTGGCGATCATCGTCCGC
GAGGTCTGGAAGATCATCCAGGCCCGGCGGCGCGGACGGGCGGCGGCGCGGCTCCACGTCCAGATCGTCAGCCTGTTCTC
GGTGATCGCCGTGCTGCCGGCGGTGCTGGTGTCGGTCGTCGCCAATGTCACGCTCGACCGCGGCCTCGACCGGCTGTTCT
CAGGGCCGACCCGGGCGGTGATCCAGAATTCGCTGATCGTCGCCAATGCCTATCTGCACGAACACGGCCAGCTGATCCGC
GGCGACATCATCGGCATGGCGAACGACATCTCGCGGGTCCGGCCGCTGTTCGACCAGGACCGCAAGTCCTTCCGCGAATT
TCTCACCACCGATGCCGCGTCGCGCAATCTTCCCGGCGCGATGCTGATCGACAAGGACCGCAACATCGTGGAGTCGGCCC
AGACCGGCATCCAGCGCGATTTCGACACGCCGGCCCCCGAATTCCTCAGCAATGTCGACGACACCGAGCCGCAGATCGCG
GTGTTCATCGAGGCCAATTACGTCGCCGCGGTGATCCGGCTGAAGGGCTTCGACGACACCTTCCTGTATGTCGCGCGGCT
GCTCGACCCCCGCGTGGTGGCGCAATTGCGGCAGACCCAGGCCAGCGTCGCCGAATATGCCGAGATCGAGGCGCGCCGGC
TCGGCGTTCAGGTCGCGTTCGCGCTGATGTTCACGGTGATCGCGCTGACGGTGCTGATGTCGTCGGTGCTGATCGGGCTG
AACTTCGCCAATTGGCTGGTGGCGCCGATCCGCCGCCTGATGGGCGCGGCGCAGATGGTCTCGACCGGCGATCTGCACGT
CCAGGTGCCGGTGTTCAAATCCGAGGGCGACCTGTCGCAACTCGGCGAGACTTTCAACAAGATGACGCAGGAGCTGCGGA
CCCAGCGCGACGAACTGGTCAGCGCCAGCGATCTGATCGACAGTCGCCGCCGCTTCATCGAAGCGGTGCTGTCGTCGGCC
AGCGCCGGCATCATCGGCGTCGACGGCTCGCTCAGCATCGGCATTCTCAACCGCTCGGCGGAGAAGCTGATCGGGCATTC
GGAATCCGAGACGCTGGGGCATCCGCTGTCCGAGGTGATTCCCGAGCTCGACGAAATGATGGCCGCGGCCTGCGAAGGCG
CGCAGCGTCTGGTGCAGGGCCAGATCACCATCACCCGCGATGGCCGCGAACGCATTCTCTCGGTGCGCGTCACGGCCGAG
CAGACCGGCCACGCCCGCGACAGCTACATCATCACGCTCGACGATATCACCGAGCTGGTGTCGGCGCAGCGGACCTCGGC
CTGGGGCGATGTCGCGCGCCGGATCGCGCACGAGATCAAGAACCCGCTGACCCCGATCCAGCTGTCGGCGGAGCGGATCA
AGCGCAAGTTCGGCAAGGTGATCGTCGAGGACAAGGGCATCTTCGAGCAGTGCACCGACACCATCGTGCGCCAGGTCGAC
GACATCCGCCGCATGGTCGACGAATTCTCGCGCTTCGCGCGGATGCCGAAGCCGGTAATCGAAGGCGAGGATGTCGCCGA
CACCGTGCGCCAGGTGGTGTTCCTGATGCGCGTCGGCCATCCCGAGGTCGAGATCGAGACCGAGATCAAGGACGACCCGC
TGCGGGCGCGGTTCGACCGCCGTCTGATTTCGCAGGCGTTGACCAACATCATCAAGAACGCGGCCGAGGCGATCGAGGCG
GTGCCGCCGGAGGAACTCGGCAAGGGCAGGATCGAGGTGGTGGCGGCGCGCGACGGCGACGACGTCGTCATCGACGTCGT
CGACAACGGCATCGGTCTGCCCAAACAAAGCCGCTCACGCCTGCTCGAACCCTACGTGACCACGCGCGAGAAGGGCACCG
GCCTCGGGCTCGCGATCGTCGGGCGCGTGCTGGTCGATCATGGCGGCGGCATCGAACTCAACGACGCATCCGACTTCCGG
CCCGGGCAACGTGGCGCGTGGATGCGGTTACGATTTGCGATGTCCGGACAGCCCGTGGCACCGCCTGCCGGTGAACCAAA
AGCCAAGGCCGGCAACGAACCGAAGATAGAAGCGGCGAACAGCGGCTAG

Upstream 100 bases:

>100_bases
CGGCGCGCCGCGATATTGTCGTAATTGAGCAACAATGTTGTAGGAATGCATCACTTGCCTTTGCGGCGGTGACCCGTCGC
ATTCATTGATTATTGCCAGA

Downstream 100 bases:

>100_bases
AATGACAGGCTCGACAAATGGCGAATGACATTTTGATCGTCGATGACGAAGCGGATATCCGCGATCTCGTCGCCGGCATT
CTCGAGGACGAAGGCTTCAC

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 762; Mature: 761

Protein sequence:

>762_residues
MTSAETSTPTVDDPSIAEPRAAFWRRLLAPIAVCVALLSAFLTFVILTGLTPIAPTRAVVVTFLLINGATILLLVAIIVR
EVWKIIQARRRGRAAARLHVQIVSLFSVIAVLPAVLVSVVANVTLDRGLDRLFSGPTRAVIQNSLIVANAYLHEHGQLIR
GDIIGMANDISRVRPLFDQDRKSFREFLTTDAASRNLPGAMLIDKDRNIVESAQTGIQRDFDTPAPEFLSNVDDTEPQIA
VFIEANYVAAVIRLKGFDDTFLYVARLLDPRVVAQLRQTQASVAEYAEIEARRLGVQVAFALMFTVIALTVLMSSVLIGL
NFANWLVAPIRRLMGAAQMVSTGDLHVQVPVFKSEGDLSQLGETFNKMTQELRTQRDELVSASDLIDSRRRFIEAVLSSA
SAGIIGVDGSLSIGILNRSAEKLIGHSESETLGHPLSEVIPELDEMMAAACEGAQRLVQGQITITRDGRERILSVRVTAE
QTGHARDSYIITLDDITELVSAQRTSAWGDVARRIAHEIKNPLTPIQLSAERIKRKFGKVIVEDKGIFEQCTDTIVRQVD
DIRRMVDEFSRFARMPKPVIEGEDVADTVRQVVFLMRVGHPEVEIETEIKDDPLRARFDRRLISQALTNIIKNAAEAIEA
VPPEELGKGRIEVVAARDGDDVVIDVVDNGIGLPKQSRSRLLEPYVTTREKGTGLGLAIVGRVLVDHGGGIELNDASDFR
PGQRGAWMRLRFAMSGQPVAPPAGEPKAKAGNEPKIEAANSG

Sequences:

>Translated_762_residues
MTSAETSTPTVDDPSIAEPRAAFWRRLLAPIAVCVALLSAFLTFVILTGLTPIAPTRAVVVTFLLINGATILLLVAIIVR
EVWKIIQARRRGRAAARLHVQIVSLFSVIAVLPAVLVSVVANVTLDRGLDRLFSGPTRAVIQNSLIVANAYLHEHGQLIR
GDIIGMANDISRVRPLFDQDRKSFREFLTTDAASRNLPGAMLIDKDRNIVESAQTGIQRDFDTPAPEFLSNVDDTEPQIA
VFIEANYVAAVIRLKGFDDTFLYVARLLDPRVVAQLRQTQASVAEYAEIEARRLGVQVAFALMFTVIALTVLMSSVLIGL
NFANWLVAPIRRLMGAAQMVSTGDLHVQVPVFKSEGDLSQLGETFNKMTQELRTQRDELVSASDLIDSRRRFIEAVLSSA
SAGIIGVDGSLSIGILNRSAEKLIGHSESETLGHPLSEVIPELDEMMAAACEGAQRLVQGQITITRDGRERILSVRVTAE
QTGHARDSYIITLDDITELVSAQRTSAWGDVARRIAHEIKNPLTPIQLSAERIKRKFGKVIVEDKGIFEQCTDTIVRQVD
DIRRMVDEFSRFARMPKPVIEGEDVADTVRQVVFLMRVGHPEVEIETEIKDDPLRARFDRRLISQALTNIIKNAAEAIEA
VPPEELGKGRIEVVAARDGDDVVIDVVDNGIGLPKQSRSRLLEPYVTTREKGTGLGLAIVGRVLVDHGGGIELNDASDFR
PGQRGAWMRLRFAMSGQPVAPPAGEPKAKAGNEPKIEAANSG
>Mature_761_residues
TSAETSTPTVDDPSIAEPRAAFWRRLLAPIAVCVALLSAFLTFVILTGLTPIAPTRAVVVTFLLINGATILLLVAIIVRE
VWKIIQARRRGRAAARLHVQIVSLFSVIAVLPAVLVSVVANVTLDRGLDRLFSGPTRAVIQNSLIVANAYLHEHGQLIRG
DIIGMANDISRVRPLFDQDRKSFREFLTTDAASRNLPGAMLIDKDRNIVESAQTGIQRDFDTPAPEFLSNVDDTEPQIAV
FIEANYVAAVIRLKGFDDTFLYVARLLDPRVVAQLRQTQASVAEYAEIEARRLGVQVAFALMFTVIALTVLMSSVLIGLN
FANWLVAPIRRLMGAAQMVSTGDLHVQVPVFKSEGDLSQLGETFNKMTQELRTQRDELVSASDLIDSRRRFIEAVLSSAS
AGIIGVDGSLSIGILNRSAEKLIGHSESETLGHPLSEVIPELDEMMAAACEGAQRLVQGQITITRDGRERILSVRVTAEQ
TGHARDSYIITLDDITELVSAQRTSAWGDVARRIAHEIKNPLTPIQLSAERIKRKFGKVIVEDKGIFEQCTDTIVRQVDD
IRRMVDEFSRFARMPKPVIEGEDVADTVRQVVFLMRVGHPEVEIETEIKDDPLRARFDRRLISQALTNIIKNAAEAIEAV
PPEELGKGRIEVVAARDGDDVVIDVVDNGIGLPKQSRSRLLEPYVTTREKGTGLGLAIVGRVLVDHGGGIELNDASDFRP
GQRGAWMRLRFAMSGQPVAPPAGEPKAKAGNEPKIEAANSG

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=375, Percent_Identity=24.2666666666667, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI1790300, Length=349, Percent_Identity=29.2263610315186, Blast_Score=107, Evalue=4e-24,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=27.5555555555556, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789808, Length=206, Percent_Identity=28.6407766990291, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 83434; Mature: 83303

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSAETSTPTVDDPSIAEPRAAFWRRLLAPIAVCVALLSAFLTFVILTGLTPIAPTRAVV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
VTFLLINGATILLLVAIIVREVWKIIQARRRGRAAARLHVQIVSLFSVIAVLPAVLVSVV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANVTLDRGLDRLFSGPTRAVIQNSLIVANAYLHEHGQLIRGDIIGMANDISRVRPLFDQD
HHHHHHHHHHHHHCCCHHHHHHCCHHEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
RKSFREFLTTDAASRNLPGAMLIDKDRNIVESAQTGIQRDFDTPAPEFLSNVDDTEPQIA
HHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCEE
VFIEANYVAAVIRLKGFDDTFLYVARLLDPRVVAQLRQTQASVAEYAEIEARRLGVQVAF
EEEECCCEEEEHEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALMFTVIALTVLMSSVLIGLNFANWLVAPIRRLMGAAQMVSTGDLHVQVPVFKSEGDLSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHH
LGETFNKMTQELRTQRDELVSASDLIDSRRRFIEAVLSSASAGIIGVDGSLSIGILNRSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCCH
EKLIGHSESETLGHPLSEVIPELDEMMAAACEGAQRLVQGQITITRDGRERILSVRVTAE
HHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEEEHH
QTGHARDSYIITLDDITELVSAQRTSAWGDVARRIAHEIKNPLTPIQLSAERIKRKFGKV
HCCCCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCE
IVEDKGIFEQCTDTIVRQVDDIRRMVDEFSRFARMPKPVIEGEDVADTVRQVVFLMRVGH
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCC
PEVEIETEIKDDPLRARFDRRLISQALTNIIKNAAEAIEAVPPEELGKGRIEVVAARDGD
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCC
DVVIDVVDNGIGLPKQSRSRLLEPYVTTREKGTGLGLAIVGRVLVDHGGGIELNDASDFR
CEEEEEECCCCCCCHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCC
PGQRGAWMRLRFAMSGQPVAPPAGEPKAKAGNEPKIEAANSG
CCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TSAETSTPTVDDPSIAEPRAAFWRRLLAPIAVCVALLSAFLTFVILTGLTPIAPTRAVV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
VTFLLINGATILLLVAIIVREVWKIIQARRRGRAAARLHVQIVSLFSVIAVLPAVLVSVV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANVTLDRGLDRLFSGPTRAVIQNSLIVANAYLHEHGQLIRGDIIGMANDISRVRPLFDQD
HHHHHHHHHHHHHCCCHHHHHHCCHHEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
RKSFREFLTTDAASRNLPGAMLIDKDRNIVESAQTGIQRDFDTPAPEFLSNVDDTEPQIA
HHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCEE
VFIEANYVAAVIRLKGFDDTFLYVARLLDPRVVAQLRQTQASVAEYAEIEARRLGVQVAF
EEEECCCEEEEHEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALMFTVIALTVLMSSVLIGLNFANWLVAPIRRLMGAAQMVSTGDLHVQVPVFKSEGDLSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHH
LGETFNKMTQELRTQRDELVSASDLIDSRRRFIEAVLSSASAGIIGVDGSLSIGILNRSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCCH
EKLIGHSESETLGHPLSEVIPELDEMMAAACEGAQRLVQGQITITRDGRERILSVRVTAE
HHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEEEHH
QTGHARDSYIITLDDITELVSAQRTSAWGDVARRIAHEIKNPLTPIQLSAERIKRKFGKV
HCCCCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCE
IVEDKGIFEQCTDTIVRQVDDIRRMVDEFSRFARMPKPVIEGEDVADTVRQVVFLMRVGH
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCC
PEVEIETEIKDDPLRARFDRRLISQALTNIIKNAAEAIEAVPPEELGKGRIEVVAARDGD
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCC
DVVIDVVDNGIGLPKQSRSRLLEPYVTTREKGTGLGLAIVGRVLVDHGGGIELNDASDFR
CEEEEEECCCCCCCHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCC
PGQRGAWMRLRFAMSGQPVAPPAGEPKAKAGNEPKIEAANSG
CCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]