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The map label for this gene is 86749840

Identifier: 86749840

GI number: 86749840

Start: 3107292

End: 3108320

Strand: Reverse

Name: 86749840

Synonym: RPB_2723

Alternate gene names: NA

Gene position: 3108320-3107292 (Counterclockwise)

Preceding gene: 86749842

Following gene: 86749838

Centisome position: 58.3

GC content: 68.03

Gene sequence:

>1029_bases
ATGCCGCCTTGGCGCGGTTGCGACACCGTGAACCGCAACCGCGCAGCCTGCGACAAAGCCGTCAACGCAGGCGCGAGGGA
AACCGACATGCGATCTCACATGGTCTCGTCGAATGTCGTGGCGGTCGCGCTGTTCGCGTTGCTGTCGCAAAGTGCCGCGG
CCGAGGACGCCGCGTGGAAAGGCTGTGTCGGACTGCAGGGCTCTCCGGCGGAGCGCGTCGCCGCCTGCAGCACGGTGATC
GAGACCAACGCCGAAACTGGCCGGCGGCTGGCGGCGGCGTATTGCAACCGGGGCCACGGCCTGACCGAACAGCGCAAGCT
CGACGAGGCGATGGCCGATCTCGAAGCGGCGGTGCGGCTCGATCCGGGATTCGCCTGCGCCTACAACAATCGGGGCCGGG
TCTATGCGTTCAAGGGAGAGGGCGATCGCGCGTTGGCCGACTACGACGAAGCAATCAGGCTCGATGCGAAATTCGCGCTG
GCCTACAACAACCGCGCCATGATCTGGCTCGCCCGGCGCGACCCCGACCGCGCACTGGACGACCTCTCCGCGGCGATCAC
AGCGGACCCGGGGCTCGCCGTCGCTTACGGCAATCGCGGCCACATCTACTATCAGCAGCGCGACATGGCTCGTGCGCTGG
CGGATTTCGACGCCGAGATCGCCTTGCGGCCCAACGTGCTCGCCTACATCAATCGCGGCAATGTCCATCGCGACACCGAG
CAACTCGACCGCGCCGCCGCGGATTACGGCGAGGCGATCCGGCTGGCGCCGGAGGACGCCCGCGGCTGGCGCAATCGGGC
GCTGATCAAGCTGTACCAGGGCGACAACAAGGGCGGCCTCGCCGACTACGACAAGGCGCTACGCTACGATCCGGCCGACG
TGTTCTCCTGGAACAACCGCGCCCAGGCCAGGATGCGGCTCGGCGACCGCAGCGGCGCGATCGCGGATTTCCGCAAGGCG
CTGGAATTGCGGCCGGGCCTGCAGACCGCGCGGGATTCGCTGAAGCGGCTCGGCGCTGCGGTGAACTGA

Upstream 100 bases:

>100_bases
CGCCCTCGCATCGACGCGCACTGTGAATCGAAGGTCCGACGTTAAAGCCATAGTGAAATGCCGGACGCAATCCGGGCAAT
CCCTGAGGTCGGCATTCCGG

Downstream 100 bases:

>100_bases
TCGCAGCGCTGCCTCGATCGATACCGTCAGCGCTTGAGCGAGTCGGCCAGCAATTTGCGCACCGACCACGCTTCGCCGTC
GACCGCGCCGCGGATGTCGT

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MPPWRGCDTVNRNRAACDKAVNAGARETDMRSHMVSSNVVAVALFALLSQSAAAEDAAWKGCVGLQGSPAERVAACSTVI
ETNAETGRRLAAAYCNRGHGLTEQRKLDEAMADLEAAVRLDPGFACAYNNRGRVYAFKGEGDRALADYDEAIRLDAKFAL
AYNNRAMIWLARRDPDRALDDLSAAITADPGLAVAYGNRGHIYYQQRDMARALADFDAEIALRPNVLAYINRGNVHRDTE
QLDRAAADYGEAIRLAPEDARGWRNRALIKLYQGDNKGGLADYDKALRYDPADVFSWNNRAQARMRLGDRSGAIADFRKA
LELRPGLQTARDSLKRLGAAVN

Sequences:

>Translated_342_residues
MPPWRGCDTVNRNRAACDKAVNAGARETDMRSHMVSSNVVAVALFALLSQSAAAEDAAWKGCVGLQGSPAERVAACSTVI
ETNAETGRRLAAAYCNRGHGLTEQRKLDEAMADLEAAVRLDPGFACAYNNRGRVYAFKGEGDRALADYDEAIRLDAKFAL
AYNNRAMIWLARRDPDRALDDLSAAITADPGLAVAYGNRGHIYYQQRDMARALADFDAEIALRPNVLAYINRGNVHRDTE
QLDRAAADYGEAIRLAPEDARGWRNRALIKLYQGDNKGGLADYDKALRYDPADVFSWNNRAQARMRLGDRSGAIADFRKA
LELRPGLQTARDSLKRLGAAVN
>Mature_341_residues
PPWRGCDTVNRNRAACDKAVNAGARETDMRSHMVSSNVVAVALFALLSQSAAAEDAAWKGCVGLQGSPAERVAACSTVIE
TNAETGRRLAAAYCNRGHGLTEQRKLDEAMADLEAAVRLDPGFACAYNNRGRVYAFKGEGDRALADYDEAIRLDAKFALA
YNNRAMIWLARRDPDRALDDLSAAITADPGLAVAYGNRGHIYYQQRDMARALADFDAEIALRPNVLAYINRGNVHRDTEQ
LDRAAADYGEAIRLAPEDARGWRNRALIKLYQGDNKGGLADYDKALRYDPADVFSWNNRAQARMRLGDRSGAIADFRKAL
ELRPGLQTARDSLKRLGAAVN

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=245, Percent_Identity=29.7959183673469, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI32307148, Length=245, Percent_Identity=29.7959183673469, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI310110582, Length=227, Percent_Identity=28.1938325991189, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI310131789, Length=227, Percent_Identity=28.1938325991189, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI310123097, Length=227, Percent_Identity=28.1938325991189, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115532692, Length=251, Percent_Identity=27.8884462151394, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI115532690, Length=254, Percent_Identity=27.5590551181102, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17647755, Length=245, Percent_Identity=30.6122448979592, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24585827, Length=245, Percent_Identity=30.6122448979592, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24585829, Length=245, Percent_Identity=30.6122448979592, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 37496; Mature: 37365

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPWRGCDTVNRNRAACDKAVNAGARETDMRSHMVSSNVVAVALFALLSQSAAAEDAAWK
CCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHC
GCVGLQGSPAERVAACSTVIETNAETGRRLAAAYCNRGHGLTEQRKLDEAMADLEAAVRL
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEE
DPGFACAYNNRGRVYAFKGEGDRALADYDEAIRLDAKFALAYNNRAMIWLARRDPDRALD
CCCEEEEECCCCCEEEECCCCCCCHHCCHHHHEECEEEEEEECCEEEEEEECCCCHHHHH
DLSAAITADPGLAVAYGNRGHIYYQQRDMARALADFDAEIALRPNVLAYINRGNVHRDTE
HHHHHEECCCCEEEEECCCCEEEEEHHHHHHHHHCCCCCEEECCCEEEEEECCCCCCCHH
QLDRAAADYGEAIRLAPEDARGWRNRALIKLYQGDNKGGLADYDKALRYDPADVFSWNNR
HHHHHHHHHCCEEEECCHHHCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCHHHCCCCCC
AQARMRLGDRSGAIADFRKALELRPGLQTARDSLKRLGAAVN
HHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PPWRGCDTVNRNRAACDKAVNAGARETDMRSHMVSSNVVAVALFALLSQSAAAEDAAWK
CCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHC
GCVGLQGSPAERVAACSTVIETNAETGRRLAAAYCNRGHGLTEQRKLDEAMADLEAAVRL
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEE
DPGFACAYNNRGRVYAFKGEGDRALADYDEAIRLDAKFALAYNNRAMIWLARRDPDRALD
CCCEEEEECCCCCEEEECCCCCCCHHCCHHHHEECEEEEEEECCEEEEEEECCCCHHHHH
DLSAAITADPGLAVAYGNRGHIYYQQRDMARALADFDAEIALRPNVLAYINRGNVHRDTE
HHHHHEECCCCEEEEECCCCEEEEEHHHHHHHHHCCCCCEEECCCEEEEEECCCCCCCHH
QLDRAAADYGEAIRLAPEDARGWRNRALIKLYQGDNKGGLADYDKALRYDPADVFSWNNR
HHHHHHHHHCCEEEECCHHHCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCHHHCCCCCC
AQARMRLGDRSGAIADFRKALELRPGLQTARDSLKRLGAAVN
HHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]