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The map label for this gene is lipB [H]

Identifier: 86749800

GI number: 86749800

Start: 3065291

End: 3066091

Strand: Direct

Name: lipB [H]

Synonym: RPB_2683

Alternate gene names: 86749800

Gene position: 3065291-3066091 (Clockwise)

Preceding gene: 86749799

Following gene: 86749808

Centisome position: 57.49

GC content: 67.29

Gene sequence:

>801_bases
ATGACGCTGATCCTGACCATTCTCGGCTCCGGCTCCTCCGCCGGCGTGCCGCGCCCGGCGCTCGGCTGGGGCGCCGCCGA
TCCGAGCAATCCGAAGAACCGCCGCCGGCGCTGCTCGCTCCTCGCGGAGCGGGTGACACCCGACGGCATCACACGGGTGC
TGATCGACACTTCGCCGGACCTGCGCGAGCAACTGATCGACGCCGACGTCGATCATCTCGATGCGGTGTTTCTGACCCAC
GAACACGCCGACCAGACCCACGGCATCGACGACCTGCGCTCGGTGGCGATGCACATGCGACGACGCATCCCGGTCTATCT
CAACCAGGCGACCGCCGAGCACGTCGTGTTCCGCTTCCACTACTGCTTTGTGACGCCGCCCGGCAGCTCCTATCCGCCGA
TTCTGGACGAGCACCGCATCGAGACCGGCGAAAGCCGCAGCATCGAAGGCGCCGGCGGCGAGCTGACGCTGGCGCCGTTC
CTGGTGCAGCACGGCGACATCCCGGCGCTCGGCTACCGCATCGGCGCCGCCGCCTACACGCCGGACGTCAGCGACATTCC
CGAGCAGAGTTTTCCGGCGCTCGAAGGCCTCGACCTGTGGATCATCGACGGCCTGCGCTACAAGCCCCACGGCAGCCATT
TCCACATCGACGCCGCGCTGGGATGGATCGACCGCTTCAAGCCGAAGCGCGCGGTGATCACCAACATGCACGCCGACATC
GACTACGAGACGCTGCGCAAGGAATTGCCCGACGGCGTGGTGCCGGGGTTCGACGGGATGCGGTTGGAAGTTGAGGGCTG
A

Upstream 100 bases:

>100_bases
TGGCCGAGGTGAGGGGCGTGACGCCCGACGAGATCGCCCGCCAGACCACGGCGAATTTCTTCAACCTGTTCGGCAAGGTG
CCGCCGCCGGACGTCGCCGC

Downstream 100 bases:

>100_bases
GGGTCGCTTCGCGCCCTCCCTCTCTGCCCGTCATTCCGGGGCGCGGGCGCAGCTCGCGAACCCGGAATCCATAACCCCAG
TGCTTGCTACTTGGCGACGG

Product: putative hydrolase

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MTLILTILGSGSSAGVPRPALGWGAADPSNPKNRRRRCSLLAERVTPDGITRVLIDTSPDLREQLIDADVDHLDAVFLTH
EHADQTHGIDDLRSVAMHMRRRIPVYLNQATAEHVVFRFHYCFVTPPGSSYPPILDEHRIETGESRSIEGAGGELTLAPF
LVQHGDIPALGYRIGAAAYTPDVSDIPEQSFPALEGLDLWIIDGLRYKPHGSHFHIDAALGWIDRFKPKRAVITNMHADI
DYETLRKELPDGVVPGFDGMRLEVEG

Sequences:

>Translated_266_residues
MTLILTILGSGSSAGVPRPALGWGAADPSNPKNRRRRCSLLAERVTPDGITRVLIDTSPDLREQLIDADVDHLDAVFLTH
EHADQTHGIDDLRSVAMHMRRRIPVYLNQATAEHVVFRFHYCFVTPPGSSYPPILDEHRIETGESRSIEGAGGELTLAPF
LVQHGDIPALGYRIGAAAYTPDVSDIPEQSFPALEGLDLWIIDGLRYKPHGSHFHIDAALGWIDRFKPKRAVITNMHADI
DYETLRKELPDGVVPGFDGMRLEVEG
>Mature_265_residues
TLILTILGSGSSAGVPRPALGWGAADPSNPKNRRRRCSLLAERVTPDGITRVLIDTSPDLREQLIDADVDHLDAVFLTHE
HADQTHGIDDLRSVAMHMRRRIPVYLNQATAEHVVFRFHYCFVTPPGSSYPPILDEHRIETGESRSIEGAGGELTLAPFL
VQHGDIPALGYRIGAAAYTPDVSDIPEQSFPALEGLDLWIIDGLRYKPHGSHFHIDAALGWIDRFKPKRAVITNMHADID
YETLRKELPDGVVPGFDGMRLEVEG

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG1235

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily I

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the lipB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB; PF00753 Lactamase_B [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 29422; Mature: 29290

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLILTILGSGSSAGVPRPALGWGAADPSNPKNRRRRCSLLAERVTPDGITRVLIDTSPD
CEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCHH
LREQLIDADVDHLDAVFLTHEHADQTHGIDDLRSVAMHMRRRIPVYLNQATAEHVVFRFH
HHHHHHHCCHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEECHHHHEEEEEEE
YCFVTPPGSSYPPILDEHRIETGESRSIEGAGGELTLAPFLVQHGDIPALGYRIGAAAYT
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCHHHHEECCEEEC
PDVSDIPEQSFPALEGLDLWIIDGLRYKPHGSHFHIDAALGWIDRFKPKRAVITNMHADI
CCHHHCCCCCCCCCCCCEEEEECCEEECCCCCEEEEHHHHHHHHHCCCCHHHEECCCCCC
DYETLRKELPDGVVPGFDGMRLEVEG
CHHHHHHHCCCCCCCCCCCEEEEECC
>Mature Secondary Structure 
TLILTILGSGSSAGVPRPALGWGAADPSNPKNRRRRCSLLAERVTPDGITRVLIDTSPD
EEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCHH
LREQLIDADVDHLDAVFLTHEHADQTHGIDDLRSVAMHMRRRIPVYLNQATAEHVVFRFH
HHHHHHHCCHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEECHHHHEEEEEEE
YCFVTPPGSSYPPILDEHRIETGESRSIEGAGGELTLAPFLVQHGDIPALGYRIGAAAYT
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCHHHHEECCEEEC
PDVSDIPEQSFPALEGLDLWIIDGLRYKPHGSHFHIDAALGWIDRFKPKRAVITNMHADI
CCHHHCCCCCCCCCCCCEEEEECCEEECCCCCEEEEHHHHHHHHHCCCCHHHEECCCCCC
DYETLRKELPDGVVPGFDGMRLEVEG
CHHHHHHHCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]